[go: up one dir, main page]

MX2015011671A - Co-administracion de esteroides y acido zoledronico para prevenir y tratar la osteoartritis. - Google Patents

Co-administracion de esteroides y acido zoledronico para prevenir y tratar la osteoartritis.

Info

Publication number
MX2015011671A
MX2015011671A MX2015011671A MX2015011671A MX2015011671A MX 2015011671 A MX2015011671 A MX 2015011671A MX 2015011671 A MX2015011671 A MX 2015011671A MX 2015011671 A MX2015011671 A MX 2015011671A MX 2015011671 A MX2015011671 A MX 2015011671A
Authority
MX
Mexico
Prior art keywords
administration
zoledronic acid
steroids
osteoarthritis
prevent
Prior art date
Application number
MX2015011671A
Other languages
English (en)
Other versions
MX377447B (es
Inventor
Ketan Desai
Original Assignee
Levolta Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Levolta Pharmaceuticals Inc filed Critical Levolta Pharmaceuticals Inc
Publication of MX2015011671A publication Critical patent/MX2015011671A/es
Publication of MX377447B publication Critical patent/MX377447B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se revela una terapia de combinación para tratar la osteoartritis. La terapia de combinación incluye la co- administración de un esteroide y Ácido Zoledrónico. La coadministración de un esteroide reduce la producción de citocinas y, en consecuencia, reduce los efectos proinflamatorios del Ácido Zoledrónico. La co-administración del Ácido Zoledrónico con esteroides trata la osteoartritis y contribuye a prevenir el inicio de la osteoartritis en pacientes en riesgo de desarrollar osteoartritis.
MX2015011671A 2013-03-08 2014-03-07 Co-administracion de esteroides y acido zoledronico para prevenir y tratar la osteoartritis. MX377447B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/791,685 US9012432B2 (en) 2013-03-08 2013-03-08 Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis
PCT/US2014/022169 WO2014138712A1 (en) 2013-03-08 2014-03-07 Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis

Publications (2)

Publication Number Publication Date
MX2015011671A true MX2015011671A (es) 2016-05-12
MX377447B MX377447B (es) 2025-03-10

Family

ID=51488530

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015011671A MX377447B (es) 2013-03-08 2014-03-07 Co-administracion de esteroides y acido zoledronico para prevenir y tratar la osteoartritis.

Country Status (12)

Country Link
US (1) US9012432B2 (es)
EP (1) EP2964209B1 (es)
JP (2) JP6839491B2 (es)
KR (1) KR102253394B1 (es)
CN (1) CN105324113B (es)
AU (1) AU2014225373B2 (es)
BR (1) BR112015021503B1 (es)
CA (1) CA2941346C (es)
EA (1) EA032067B1 (es)
ES (1) ES2904365T3 (es)
MX (1) MX377447B (es)
WO (1) WO2014138712A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10913772B2 (en) 2016-03-09 2021-02-09 Kine Sciences Co., Ltd. Peptide for preventing or treating inflammatory diseases and use thereof
KR101897122B1 (ko) 2016-03-09 2018-09-10 주식회사 바이오펩 염증성 질환의 예방 또는 치료용 펩타이드 및 이의 용도
US10913771B2 (en) 2016-03-09 2021-02-09 Kine Sciences Co., Ltd. Peptide for preventing or treating inflammatory diseases and use thereof
WO2017155234A1 (ko) 2016-03-09 2017-09-14 주식회사 바이오펩 염증성 질환의 예방 또는 치료용 펩타이드 및 이의 용도
WO2017155233A1 (ko) 2016-03-09 2017-09-14 주식회사 바이오펩 염증성 질환의 예방 또는 치료용 펩타이드 및 이의 용도
JP7127616B2 (ja) 2019-06-04 2022-08-30 横河電機株式会社 情報処理装置、アラーム管理システム、及びアラーム管理方法
WO2021163432A1 (en) * 2020-02-12 2021-08-19 Levolta Pharmaceuticals, Inc. Co-administration of prednisolone/methyl prednisolone and zoledronic acid to treat and prevent osteoarthritis
CN114028571B (zh) * 2021-11-18 2023-04-28 中国医学科学院基础医学研究所 含氮双膦酸盐联合糖皮质激素在预防或治疗病毒性肺炎中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE72816T1 (de) 1986-11-21 1992-03-15 Ciba Geigy Ag Neue substituierte alkandiphosphonsaeuren.
US7018647B1 (en) * 1999-12-27 2006-03-28 Teikoku Seiyaku Co., Ltd Patches for external use
GB0029111D0 (en) * 2000-11-29 2001-01-10 Novartis Ag Organic compounds
JP2005516888A (ja) * 2001-06-08 2005-06-09 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 過分極活性化型環状ヌクレオチド依存性チャンネルに標的を定めることによる疼痛の治療
US20050176685A1 (en) * 2002-04-05 2005-08-11 Daifotis Anastasia G. Method for inhibiting bone resorption with an alendronate and vitamin d formulation
WO2005027921A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a bisphosphonate
US20090035315A1 (en) * 2004-06-17 2009-02-05 Stephan Christgau Method of Improving Treatments in Rheumatic and Arthritic Diseases
EP1890727B1 (en) * 2005-05-25 2012-10-03 CaloSyn Pharma, Inc Method and composition for treating osteoarthritis
US20070048372A1 (en) * 2005-08-18 2007-03-01 Srz Properties, Inc. Method for treating non-inflammatory osteoarthritic pain
PT2049123E (pt) * 2006-08-03 2013-03-06 Horizon Pharma Ag Tratamento de doença reumatóide com glucocorticóide de libertação retardada
US20100158905A1 (en) * 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Combination therapy of arthritis with tranilast
MX2011011698A (es) * 2009-05-04 2012-02-29 Zars Pharma Inc Metodo para tratar dolores asociados con neuroma, entrapamiento nervioso y otras condiciones.
US8946199B2 (en) 2010-04-26 2015-02-03 Ketan Desai Co-administration of steroids and Zoledronic acid to prevent and treat side effects from Zoledronic acid infusion

Also Published As

Publication number Publication date
MX377447B (es) 2025-03-10
KR20150125001A (ko) 2015-11-06
CN105324113B (zh) 2018-07-03
EP2964209A1 (en) 2016-01-13
AU2014225373B2 (en) 2018-07-05
JP2019104762A (ja) 2019-06-27
JP2016510765A (ja) 2016-04-11
US20140256681A1 (en) 2014-09-11
KR102253394B1 (ko) 2021-05-20
EA032067B1 (ru) 2019-04-30
AU2014225373A1 (en) 2015-10-22
CA2941346C (en) 2020-03-10
EA201591638A1 (ru) 2016-02-29
BR112015021503A2 (en) 2018-05-15
US9012432B2 (en) 2015-04-21
ES2904365T3 (es) 2022-04-04
CN105324113A (zh) 2016-02-10
WO2014138712A1 (en) 2014-09-12
BR112015021503B1 (pt) 2022-09-06
EP2964209A4 (en) 2016-08-03
CA2941346A1 (en) 2014-09-12
JP6839491B2 (ja) 2021-03-17
EP2964209B1 (en) 2021-10-27

Similar Documents

Publication Publication Date Title
MX2015011671A (es) Co-administracion de esteroides y acido zoledronico para prevenir y tratar la osteoartritis.
EA201790737A1 (ru) Комбинированная терапия
CR20150376A (es) Compuestos sustituidos de pirrolopirimidina, compuestos de los mismos y metodos de tratamiento con los mismos
ES2765949T8 (es) Terapia que involucra anticuerpos contra la claudina 18.2 para el tratamiento del cáncer
MX2020011772A (es) Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer.
NI201400112A (es) Tratamiento del cáncer con inhibidores tor cinasa
MX380370B (es) Modulador del receptor de androgeno y usos de este.
UY36307A (es) Terapias combinadas para el tratamiento del cáncer
CL2016000354A1 (es) Modulación de la inmunidad tumoral
MX2017013802A (es) Métodos para tratar el cáncer.
AR102553A1 (es) Terapia de combinación con agonistas de unión ox40 e inhibidores de tigit
MX2016005294A (es) Metodos para tratar y prevenir enfermedad injerto contra huésped.
CL2016000055A1 (es) Métodos para tratar o prevenir afecciones oftalmológicas
EA201690206A1 (ru) Терапевтически активные соединения и способы их применения
CL2017000290A1 (es) Inhibidores de la proteína kinasa c y métodos de su uso.
MX2015016100A (es) Inhibidores de criopirina para prevenir y tratar la inflamacion.
BR112017018964A2 (pt) uso de plinabulin e métodos para tratar tumor cerebral
EP3141603A4 (en) Gpc3-targeted therapeutic agent for administration to patients for whom gpc3-targeted therapeutic agent therapy is effective
NI201500150A (es) TRATAMIENTO DE CÁNCER CON DIHIDROPIRAZINO-PIRAZINAS×Se proporcionan en la presente método
MX2015014344A (es) Terapia contra el cancer.
MX2016013245A (es) Regimen de dosificacion de liberacion inmediata de moduladores s1p.
MX2021007899A (es) Composiciones con inhibidor selectivo de la trans-se?alizacion de il-6.
NI201500151A (es) Terapia de combinación que comprende un compuesto de dihidropirazino-pirazina y un antagonista de receptor de andrógenos para tratar cáncer de próstata.
CR20140400A (es) Terapia combinada para el tratamiento del cancer de ovario
UY36286A (es) Tratamientos médicos basados en anamorelina

Legal Events

Date Code Title Description
FG Grant or registration