MX2015010296A - Tratamiento de formas progresivas de esclerosis multiple con laquinimod. - Google Patents
Tratamiento de formas progresivas de esclerosis multiple con laquinimod.Info
- Publication number
- MX2015010296A MX2015010296A MX2015010296A MX2015010296A MX2015010296A MX 2015010296 A MX2015010296 A MX 2015010296A MX 2015010296 A MX2015010296 A MX 2015010296A MX 2015010296 A MX2015010296 A MX 2015010296A MX 2015010296 A MX2015010296 A MX 2015010296A
- Authority
- MX
- Mexico
- Prior art keywords
- laquinimod
- multiple sclerosis
- human subject
- treating
- treatment
- Prior art date
Links
- GKWPCEFFIHSJOE-UHFFFAOYSA-N laquinimod Chemical compound OC=1C2=C(Cl)C=CC=C2N(C)C(=O)C=1C(=O)N(CC)C1=CC=CC=C1 GKWPCEFFIHSJOE-UHFFFAOYSA-N 0.000 title abstract 4
- 229960004577 laquinimod Drugs 0.000 title abstract 4
- 201000006417 multiple sclerosis Diseases 0.000 title abstract 4
- 230000000750 progressive effect Effects 0.000 abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Esta invención proporciona un método para tratar a un sujeto humano afligido con una forma progresiva de esclerosis múltiple, que comprende administrar periódicamente al sujeto humano una cantidad de laquinimod efectiva para tratar al sujeto humano. Esta invención también proporciona laquinimod para utilizarse en el tratamiento de un sujeto humano afligido con una forma progresiva de esclerosis múltiple. Esta invención proporciona además las composiciones farmacéuticas y paquetes que comprenden una cantidad efectiva de laquinimod para tratar una forma progresiva de esclerosis múltiple.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361765394P | 2013-02-15 | 2013-02-15 | |
| US201361911106P | 2013-12-03 | 2013-12-03 | |
| PCT/US2014/016278 WO2014127139A1 (en) | 2013-02-15 | 2014-02-13 | Treatment of multiple sclerosis with laquinimod |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015010296A true MX2015010296A (es) | 2016-05-05 |
Family
ID=51351655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015010296A MX2015010296A (es) | 2013-02-15 | 2014-02-13 | Tratamiento de formas progresivas de esclerosis multiple con laquinimod. |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20140235670A1 (es) |
| EP (1) | EP2956137A4 (es) |
| JP (1) | JP2016510343A (es) |
| KR (1) | KR20150119227A (es) |
| CN (1) | CN105163737A (es) |
| AU (1) | AU2014216199A1 (es) |
| BR (1) | BR112015019564A2 (es) |
| CA (1) | CA2900503A1 (es) |
| CL (1) | CL2015002181A1 (es) |
| EA (1) | EA201591507A1 (es) |
| HK (2) | HK1218254A1 (es) |
| IL (1) | IL240014A0 (es) |
| MX (1) | MX2015010296A (es) |
| PE (1) | PE20151526A1 (es) |
| SG (1) | SG11201505818WA (es) |
| TW (1) | TW201442709A (es) |
| UY (1) | UY35328A (es) |
| WO (1) | WO2014127139A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9161935B2 (en) | 2012-02-03 | 2015-10-20 | Teva Pharmaceutical Industries, Ltd. | Use of laquinimod for treating Crohn's disease patients who failed first-line anti-TNF therapy |
| TW201804997A (zh) * | 2012-05-02 | 2018-02-16 | 以色列商泰瓦藥品工業有限公司 | 高劑量拉喹莫德(laquinimod)於治療多發性硬化症之用途 |
| WO2015168103A1 (en) | 2014-04-29 | 2015-11-05 | Teva Pharmaceutical Industries Ltd. | Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status |
| KR20170068480A (ko) | 2014-10-16 | 2017-06-19 | 노파르티스 아게 | 다발성 경화증의 치료를 위한 시포니모드 및 라퀴니모드를 포함하는 조합물 |
| US10091217B2 (en) | 2016-06-21 | 2018-10-02 | Logrhythm, Inc. | Risk based priority processing of data |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| FI3506921T3 (fi) | 2016-08-31 | 2023-07-21 | Mapi Pharma Ltd | Glatirameeriasetaattia käsittäviä depot-järjestelmiä |
| MX2019010174A (es) | 2017-03-26 | 2019-10-15 | Mapi Pharma Ltd | Sistemas de deposito de glatiramer para el tratamiento de formas progresivas de esclerosis multiple. |
| US20230296628A1 (en) * | 2020-07-09 | 2023-09-21 | Oklahoma Medical Research Foundation | Biomarkers for Identifying Relapses in Multiple Sclerosis |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9801474D0 (sv) * | 1998-04-27 | 1998-04-27 | Active Biotech Ab | Quinoline Derivatives |
| US6077851A (en) * | 1998-04-27 | 2000-06-20 | Active Biotech Ab | Quinoline derivatives |
| CN101466379B (zh) * | 2006-06-12 | 2012-10-31 | 泰华制药工业有限公司 | 稳定的拉喹莫德的制剂 |
| BRPI0814624A2 (pt) * | 2007-07-11 | 2015-01-27 | Medicinova Inc | Tratamento de doença neurodegenerativa progresiva com ibudilaste |
| AR073295A1 (es) * | 2008-09-16 | 2010-10-28 | Genentech Inc | Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion. |
| EP2375900B1 (en) * | 2008-12-11 | 2016-03-02 | Biovista, Inc. | Methods for treating multiple sclerosis using tetracyclic pyrazinoindoles |
| EA201270041A1 (ru) * | 2009-06-19 | 2012-06-29 | Тева Фармасьютикал Индастриз Лтд. | Лечение рассеянного склероза лаквинимодом |
| EP2648732A4 (en) * | 2010-12-07 | 2014-04-30 | Teva Pharma | USE OF LAQUINIMOD TO REDUCE TEMPERATURE, IMPROVE FUNCTIONAL STATUS AND IMPROVE LIFE QUALITY IN PATIENTS WITH MULTIPLE SCLEROSIS |
| HK1198278A1 (en) * | 2011-07-28 | 2015-03-27 | Teva Pharmaceutical Industries Ltd. | Treatment of multiple sclerosis with combination of laquinimod and interferon-beta |
| TW201804997A (zh) * | 2012-05-02 | 2018-02-16 | 以色列商泰瓦藥品工業有限公司 | 高劑量拉喹莫德(laquinimod)於治療多發性硬化症之用途 |
| EP2961406A4 (en) * | 2012-10-12 | 2017-01-04 | Teva Pharmaceutical Industries Ltd. | Laquinimod for reducing thalamic damage in multiple sclerosis |
| WO2015168103A1 (en) * | 2014-04-29 | 2015-11-05 | Teva Pharmaceutical Industries Ltd. | Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status |
-
2014
- 2014-02-13 CA CA2900503A patent/CA2900503A1/en not_active Abandoned
- 2014-02-13 HK HK16106269.3A patent/HK1218254A1/zh unknown
- 2014-02-13 EA EA201591507A patent/EA201591507A1/ru unknown
- 2014-02-13 KR KR1020157024953A patent/KR20150119227A/ko not_active Withdrawn
- 2014-02-13 MX MX2015010296A patent/MX2015010296A/es unknown
- 2014-02-13 BR BR112015019564A patent/BR112015019564A2/pt active Search and Examination
- 2014-02-13 US US14/180,173 patent/US20140235670A1/en not_active Abandoned
- 2014-02-13 AU AU2014216199A patent/AU2014216199A1/en not_active Abandoned
- 2014-02-13 SG SG11201505818WA patent/SG11201505818WA/en unknown
- 2014-02-13 WO PCT/US2014/016278 patent/WO2014127139A1/en not_active Ceased
- 2014-02-13 HK HK16106220.1A patent/HK1218251A1/zh unknown
- 2014-02-13 EP EP14751103.4A patent/EP2956137A4/en not_active Withdrawn
- 2014-02-13 PE PE2015001745A patent/PE20151526A1/es not_active Application Discontinuation
- 2014-02-13 CN CN201480009035.XA patent/CN105163737A/zh active Pending
- 2014-02-13 JP JP2015558130A patent/JP2016510343A/ja active Pending
- 2014-02-14 TW TW103104987A patent/TW201442709A/zh unknown
- 2014-02-14 UY UY0001035328A patent/UY35328A/es not_active Application Discontinuation
-
2015
- 2015-07-19 IL IL240014A patent/IL240014A0/en unknown
- 2015-08-05 CL CL2015002181A patent/CL2015002181A1/es unknown
-
2017
- 2017-11-13 US US15/811,139 patent/US20180064702A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EA201591507A1 (ru) | 2015-12-30 |
| IL240014A0 (en) | 2015-09-24 |
| CN105163737A (zh) | 2015-12-16 |
| UY35328A (es) | 2014-09-30 |
| US20140235670A1 (en) | 2014-08-21 |
| TW201442709A (zh) | 2014-11-16 |
| SG11201505818WA (en) | 2015-08-28 |
| CL2015002181A1 (es) | 2016-06-03 |
| PE20151526A1 (es) | 2015-11-20 |
| EP2956137A4 (en) | 2016-08-03 |
| WO2014127139A1 (en) | 2014-08-21 |
| BR112015019564A2 (pt) | 2017-07-18 |
| JP2016510343A (ja) | 2016-04-07 |
| HK1218251A1 (zh) | 2017-02-10 |
| AU2014216199A1 (en) | 2015-09-03 |
| KR20150119227A (ko) | 2015-10-23 |
| CA2900503A1 (en) | 2014-08-21 |
| US20180064702A1 (en) | 2018-03-08 |
| EP2956137A1 (en) | 2015-12-23 |
| HK1218254A1 (zh) | 2017-02-10 |
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