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MX2014015285A - Produccion biotecnologica de acido 2-hidroxiisobutirico. - Google Patents

Produccion biotecnologica de acido 2-hidroxiisobutirico.

Info

Publication number
MX2014015285A
MX2014015285A MX2014015285A MX2014015285A MX2014015285A MX 2014015285 A MX2014015285 A MX 2014015285A MX 2014015285 A MX2014015285 A MX 2014015285A MX 2014015285 A MX2014015285 A MX 2014015285A MX 2014015285 A MX2014015285 A MX 2014015285A
Authority
MX
Mexico
Prior art keywords
hydroxyisobutyric acid
bacterium
biotechnological
acid production
acetogenic
Prior art date
Application number
MX2014015285A
Other languages
English (en)
Inventor
Thomas Haas
Yvonne Schiemann
Denise Przybylski
Thore Rohwerder
Roland H Müller
Hauke Harms
Original Assignee
Evonik Industries Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Industries Ag filed Critical Evonik Industries Ag
Publication of MX2014015285A publication Critical patent/MX2014015285A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/52—Propionic acid; Butyric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/99—Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente invención se refiere a una bacteria del gas detonante o bacteria acetogénica que expresan una 2-hidroxiisobutiril-coenzi ma A mutasa, a un método para la producción de ácido 2-hidroxiisobutírico, que comprende poner en contacto en un medio acuoso la bacteria del gas detonante o acetogénica con una mezcla de gas que comprende hidrógeno y dióxido de carbono y al uso de la bacteria del gas detonante o bacteria acetogénica para la producción de ácido 2-hidroxiisobutírico.
MX2014015285A 2012-06-15 2013-06-14 Produccion biotecnologica de acido 2-hidroxiisobutirico. MX2014015285A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12172192 2012-06-15
EP20120173010 EP2674489A1 (en) 2012-06-15 2012-06-21 Biotechnological 2-hydroxyisobutyric acid production
PCT/EP2013/062336 WO2013186340A1 (en) 2012-06-15 2013-06-14 Biotechnological 2-hydroxyisobutyric acid production

Publications (1)

Publication Number Publication Date
MX2014015285A true MX2014015285A (es) 2015-02-20

Family

ID=46354049

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014015285A MX2014015285A (es) 2012-06-15 2013-06-14 Produccion biotecnologica de acido 2-hidroxiisobutirico.

Country Status (9)

Country Link
US (1) US20150267231A1 (es)
EP (2) EP2674489A1 (es)
KR (1) KR20150018813A (es)
CN (1) CN104364373A (es)
BR (1) BR112014030760A2 (es)
CA (1) CA2875453A1 (es)
MX (1) MX2014015285A (es)
RU (1) RU2015100279A (es)
WO (1) WO2013186340A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2602328A1 (de) * 2011-12-05 2013-06-12 Evonik Industries AG Verfahren zur Oxidation von Alkanen unter Verwendung einer AlkB Alkan 1-Monooxygenase
EP2631298A1 (en) 2012-02-22 2013-08-28 Evonik Industries AG Biotechnological method for producing butanol and butyric acid
EP2647696A1 (de) 2012-04-02 2013-10-09 Evonik Degussa GmbH Verfahren zur aeroben Herstellung von Alanin oder einer unter Verbrauch von Alanin entstehenden Verbindung
DE102012207921A1 (de) 2012-05-11 2013-11-14 Evonik Industries Ag Mehrstufiges Syntheseverfahren mit Synthesegas
EP2759598A1 (de) 2013-01-24 2014-07-30 Evonik Industries AG Verfahren zur Herstellung von alpha, omega-Alkandiol
EP2944697A1 (en) 2014-05-13 2015-11-18 Evonik Degussa GmbH Method of producing nylon
EP3020819A1 (en) * 2014-11-17 2016-05-18 Evonik Degussa GmbH Fatty acid and derivatives production
CA2937594A1 (en) 2015-02-26 2016-08-26 Evonik Degussa Gmbh Alkene production
US11174496B2 (en) 2015-12-17 2021-11-16 Evonik Operations Gmbh Genetically modified acetogenic cell
WO2017165397A1 (en) 2016-03-22 2017-09-28 University Of Georgia Research Foundation, Inc. Genetically engineered microbes and methods for producing citramalate
US11124813B2 (en) 2016-07-27 2021-09-21 Evonik Operations Gmbh N-acetyl homoserine
ES2808800T3 (es) 2016-12-22 2021-03-01 Evonik Operations Gmbh Compuestos a base de aductos con isocianatos para composiciones de revestimiento
CN109868231B (zh) * 2017-12-01 2022-05-06 中国科学院烟台海岸带研究所 一种贪铜菌(Cupriavidus)及其应用
US11661613B2 (en) 2018-02-01 2023-05-30 Inv Nylon Chemicals Americas, Llc Methods and materials for the biosynthesis of hydroxy fatty acid anions and/or derivatives thereof and/or compounds related thereto
US12338428B2 (en) 2018-03-30 2025-06-24 Inv Nylon Chemicals Americas, Llc Materials and methods for managing aerobic gas fermentation
US11512276B2 (en) 2018-03-30 2022-11-29 Inv Nylon Chemicals Americas, Llc Methods for controlling oxygen concentration during aerobic biosynthesis
US12065636B2 (en) 2018-03-30 2024-08-20 Inv Nylon Chemicals Americas, Llc High hydrogen utilization and gas recycle
US10975363B2 (en) 2018-03-30 2021-04-13 Inv Nylon Chemicals Americas, Llc Materials and methods for biosynthetic manufacture and utilization of synthetic polypeptides, and products therefrom
EP3775246A1 (en) 2018-03-30 2021-02-17 INVISTA Textiles (U.K.) Limited Materials and methods for biosynthetic manufacture of carbon-based chemicals
US11702680B2 (en) 2018-05-02 2023-07-18 Inv Nylon Chemicals Americas, Llc Materials and methods for controlling PHA biosynthesis in PHA-generating species of the genera Ralstonia or Cupriavidus and organisms related thereto
US11053287B2 (en) 2018-05-02 2021-07-06 Inv Nylon Chemicals Americas, Llc Materials and methods for differential biosynthesis in species of the genera Ralstonia and Cupriavidus and organisms related thereto
US11999943B2 (en) 2018-05-02 2024-06-04 Inv Nylon Chemicals Americas, Llc Materials and methods for maximizing biosynthesis through alteration of pyruvate-acetyl-CoA-TCA balance in species of the genera ralstonia and cupriavidus and organisms related thereto
EP3788057A1 (en) 2018-05-02 2021-03-10 INVISTA Textiles (U.K.) Limited Materials and methods for controlling regulation in biosynthesis in species of the genera ralstonia or cupriavidus and organisms related thereto
US11788055B2 (en) 2018-05-02 2023-10-17 Inv Nylon Chemicals Americas, Llc Materials and methods for controlling oxidation and reduction in biosynthetic pathways of species of the genera ralstonia and cupriavidus and organisms related thereto
FI129574B (en) * 2021-04-28 2022-05-13 Solar Foods Oy Variant bacterial strains and processes for protein or biomass production

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003014330A2 (en) 2001-08-06 2003-02-20 Degussa Ag Coryneform bacteria which produce chemical compounds ii
BR0211723A (pt) 2001-08-06 2004-09-21 Degussa Bactérias corineformes que produzem compostos quìmicos i
DE102006017760A1 (de) * 2006-03-24 2007-09-27 Ufz-Umweltforschungszentrum Leipzig-Halle Gmbh Verfahren zur enzymatischen Herstellung von 2-Hydroxy-2-methylcarbonsäuren
WO2009135074A2 (en) * 2008-05-01 2009-11-05 Genomatica, Inc. Microorganisms for the production of methacrylic acid
DE102008002715A1 (de) 2008-06-27 2009-12-31 Evonik Röhm Gmbh 2-Hydroxyisobuttersäure produzierende rekombinante Zelle
WO2010022763A1 (en) * 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
DE102009046623A1 (de) * 2009-11-11 2011-05-12 Evonik Röhm Gmbh Verwendung eines zu einem MeaB-Protein homologen Proteins zur Erhöhung der enzymatischen Aktivität einer 3-Hydroxycarbonsäure-CoA-Mutase

Also Published As

Publication number Publication date
EP2674489A1 (en) 2013-12-18
EP2861730A1 (en) 2015-04-22
CN104364373A (zh) 2015-02-18
RU2015100279A (ru) 2016-08-10
WO2013186340A1 (en) 2013-12-19
US20150267231A1 (en) 2015-09-24
KR20150018813A (ko) 2015-02-24
BR112014030760A2 (pt) 2017-07-25
CA2875453A1 (en) 2013-12-19

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