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MX2014014021A - Composiciones y metodos de polipeptidos-complejo de quelato de oligonucleotido. - Google Patents

Composiciones y metodos de polipeptidos-complejo de quelato de oligonucleotido.

Info

Publication number
MX2014014021A
MX2014014021A MX2014014021A MX2014014021A MX2014014021A MX 2014014021 A MX2014014021 A MX 2014014021A MX 2014014021 A MX2014014021 A MX 2014014021A MX 2014014021 A MX2014014021 A MX 2014014021A MX 2014014021 A MX2014014021 A MX 2014014021A
Authority
MX
Mexico
Prior art keywords
methods
chelate complex
polypeptide compositions
oligonucleotide chelate
polypeptide
Prior art date
Application number
MX2014014021A
Other languages
English (en)
Other versions
MX346239B (es
Inventor
Andrew Vaillant
Michel Bazinet
Original Assignee
Replicor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49581470&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2014014021(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Replicor Inc filed Critical Replicor Inc
Publication of MX2014014021A publication Critical patent/MX2014014021A/es
Publication of MX346239B publication Critical patent/MX346239B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2292—Thymosin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se describe una composición farmacéutica que contiene un complejo de quelato de oligonucleótido y al menos un polipéptido o polipéptido pegilado. La presente descripción también describe composiciones farmacéuticas adicionales y métodos para el tratamiento de enfermedades que incluyen infecciones virales.
MX2014014021A 2012-05-18 2013-05-17 Composiciones y metodos de polipeptidos-complejo de quelato de oligonucleotido. MX346239B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261648711P 2012-05-18 2012-05-18
US201261695035P 2012-08-30 2012-08-30
PCT/CA2013/050379 WO2013170386A1 (en) 2012-05-18 2013-05-17 Oligonucleotide chelate complex-polypeptide compositions and methods

Publications (2)

Publication Number Publication Date
MX2014014021A true MX2014014021A (es) 2015-02-10
MX346239B MX346239B (es) 2017-03-13

Family

ID=49581470

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014014021A MX346239B (es) 2012-05-18 2013-05-17 Composiciones y metodos de polipeptidos-complejo de quelato de oligonucleotido.

Country Status (34)

Country Link
US (1) US9492506B2 (es)
EP (1) EP2849798B1 (es)
JP (1) JP2015517504A (es)
KR (1) KR102068109B1 (es)
CN (1) CN104349793B (es)
AU (1) AU2013262416B2 (es)
BR (1) BR112014028654A2 (es)
CA (1) CA2873529C (es)
CL (1) CL2014003134A1 (es)
CO (1) CO7131387A2 (es)
CR (1) CR20140527A (es)
CY (1) CY1124345T1 (es)
DK (1) DK2849798T3 (es)
DO (1) DOP2014000264A (es)
EA (1) EA035967B1 (es)
EC (1) ECSP14027694A (es)
ES (1) ES2873844T3 (es)
HR (1) HRP20210840T1 (es)
HU (1) HUE054875T2 (es)
IL (1) IL235548B (es)
LT (1) LT2849798T (es)
MX (1) MX346239B (es)
MY (1) MY168778A (es)
NZ (1) NZ703095A (es)
PH (1) PH12014502551B1 (es)
PL (1) PL2849798T3 (es)
PT (1) PT2849798T (es)
RS (1) RS62030B1 (es)
SG (1) SG11201407599SA (es)
SI (1) SI2849798T1 (es)
SM (1) SMT202100319T1 (es)
TW (1) TWI635864B (es)
WO (1) WO2013170386A1 (es)
ZA (1) ZA201408674B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2158316T3 (en) 2007-05-11 2015-07-20 Adynxx Inc Gene expression and pain
AU2013259402B2 (en) 2012-05-10 2017-12-21 Adynxx, Inc. Formulations for the delivery of active ingredients
EP2890403A4 (en) 2012-08-30 2016-03-09 Replicor Inc METHOD FOR THE TREATMENT OF HEPATITIS B AND HEPATITIS D INFECTIONS
SMT202300380T1 (it) * 2014-07-10 2024-01-10 Replicor Inc Polimeri chelati di acido nucleico fosforotioato da utilizzare in combinazione con un inibitore della polimerasi hbv per il trattamento delle infezioni da virus dell'epatite b e dell'epatite d
ES2750689T3 (es) 2014-08-15 2020-03-26 Adynxx Inc Señuelos oligonucleotídicos para el tratamiento del dolor
US20200147124A1 (en) * 2018-11-08 2020-05-14 Aligos Therapeutics, Inc. S-antigen transport inhibiting oligonucleotide polymers and methods
US11166976B2 (en) 2018-11-08 2021-11-09 Aligos Therapeutics, Inc. S-antigen transport inhibiting oligonucleotide polymers and methods
WO2024255846A1 (en) * 2023-06-16 2024-12-19 Ractigen Therapeutics Oligonucleotide formulation

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2769114B2 (ja) * 1993-10-29 1998-06-25 サイクローン・ファーマシューティカルズ ミニマルｂ型肝炎感染症治療用医薬組成物
UA78726C2 (en) * 2001-11-01 2007-04-25 Sciclone Pharmaceuticals Inc Pharmaceutical composition of thymosin alpha 1 conjugated with polyethylene glycol, method for production, and method for treatment
CA2498777C (en) * 2002-09-13 2015-01-13 Replicor, Inc. Non-sequence complementary antiviral oligonucleotides
JP2006519235A (ja) * 2003-02-26 2006-08-24 インターミューン インコーポレイティッド ポリエチレングリコール修飾インターフェロン組成物およびその使用方法
JP2007509950A (ja) * 2003-10-27 2007-04-19 バーテックス　ファーマシューティカルズ　インコーポレイテッド Ｈｃｖ処置の組合せ剤
EP1802643A1 (en) * 2004-10-19 2007-07-04 Replicor Inc. Antiviral oligonucleotides
WO2007022642A2 (en) * 2005-08-25 2007-03-01 Replicor Inc. Anti-inflammatory molecules and their uses
CA2624686A1 (en) * 2005-09-29 2007-04-05 Replicor Inc. Therapeutic molecules and their uses
WO2007041279A2 (en) * 2005-09-29 2007-04-12 S-Cell Biosciences, Inc. Methods to treat t-cell disorders using tisf
GB0715383D0 (en) * 2007-08-08 2007-09-19 Asterion Ltd Interferon
WO2009065181A1 (en) * 2007-11-21 2009-05-28 Apollo Life Sciences Limited Nanostructures suitable for delivery of agents
WO2009076679A2 (en) 2007-12-13 2009-06-18 Alnylam Pharmaceuticals Inc. Methods and compositions for prevention or treatment of rsv infection
AU2009221064B2 (en) * 2008-03-07 2014-12-11 Roche Innovation Center Copenhagen A/S Pharmaceutical compositions for treatment of microRNA related diseases
ES2618576T3 (es) * 2009-05-28 2017-06-21 Curna, Inc. Tratamiento de enfermedades relacionadas con un gen antivírico mediante la inhibición de una transcripción antisentido natural a un gen antivírico
AU2010306639B2 (en) * 2009-10-16 2017-02-16 Glaxo Group Limited HBV antisense inhibitors
SI2605794T1 (sl) * 2010-08-20 2017-01-31 Replicor Inc. Oligonukleotidni kelatni kompleksi
EP2890403A4 (en) 2012-08-30 2016-03-09 Replicor Inc METHOD FOR THE TREATMENT OF HEPATITIS B AND HEPATITIS D INFECTIONS

Also Published As

Publication number Publication date
US20130309201A1 (en) 2013-11-21
DOP2014000264A (es) 2015-01-31
EP2849798B1 (en) 2021-04-07
EA035967B1 (ru) 2020-09-07
NZ703095A (en) 2016-07-29
IL235548A0 (en) 2015-01-29
IL235548B (en) 2019-07-31
KR102068109B1 (ko) 2020-01-21
SMT202100319T1 (it) 2021-09-14
CO7131387A2 (es) 2014-12-01
RS62030B1 (sr) 2021-07-30
HUE054875T2 (hu) 2021-10-28
EP2849798A4 (en) 2016-03-09
TW201408308A (zh) 2014-03-01
ZA201408674B (en) 2016-01-27
AU2013262416A1 (en) 2014-12-18
CA2873529C (en) 2020-08-18
EP2849798A1 (en) 2015-03-25
JP2015517504A (ja) 2015-06-22
AU2013262416B2 (en) 2017-05-11
HRP20210840T1 (hr) 2021-08-06
CA2873529A1 (en) 2013-11-21
PT2849798T (pt) 2021-05-18
US9492506B2 (en) 2016-11-15
LT2849798T (lt) 2021-08-10
ECSP14027694A (es) 2015-12-31
DK2849798T3 (da) 2021-05-31
SG11201407599SA (en) 2014-12-30
CN104349793A (zh) 2015-02-11
KR20150013309A (ko) 2015-02-04
PH12014502551B1 (en) 2019-10-11
ES2873844T3 (es) 2021-11-04
EA201401278A1 (ru) 2015-04-30
MX346239B (es) 2017-03-13
HK1204279A1 (en) 2015-11-13
CL2014003134A1 (es) 2015-02-13
CR20140527A (es) 2014-12-15
MY168778A (en) 2018-12-04
CY1124345T1 (el) 2022-07-22
PL2849798T3 (pl) 2021-10-18
WO2013170386A1 (en) 2013-11-21
CN104349793B (zh) 2017-11-10
TWI635864B (zh) 2018-09-21
SI2849798T1 (sl) 2021-08-31
BR112014028654A2 (pt) 2017-10-10
PH12014502551A1 (en) 2015-01-21

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