[go: up one dir, main page]

MX2014010323A - Composiciones de ciclodextrina alquilada y procesos para preparar y utilizar las mismas. - Google Patents

Composiciones de ciclodextrina alquilada y procesos para preparar y utilizar las mismas.

Info

Publication number
MX2014010323A
MX2014010323A MX2014010323A MX2014010323A MX2014010323A MX 2014010323 A MX2014010323 A MX 2014010323A MX 2014010323 A MX2014010323 A MX 2014010323A MX 2014010323 A MX2014010323 A MX 2014010323A MX 2014010323 A MX2014010323 A MX 2014010323A
Authority
MX
Mexico
Prior art keywords
processes
preparing
same
alkylated cyclodextrin
cyclodextrin compositions
Prior art date
Application number
MX2014010323A
Other languages
English (en)
Other versions
MX353603B (es
Inventor
Vincent D Antle
Original Assignee
Cydex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49083249&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2014010323(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cydex Pharmaceuticals Inc filed Critical Cydex Pharmaceuticals Inc
Publication of MX2014010323A publication Critical patent/MX2014010323A/es
Publication of MX353603B publication Critical patent/MX353603B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B32/00Carbon; Compounds thereof
    • C01B32/30Active carbon
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B32/00Carbon; Compounds thereof
    • C01B32/30Active carbon
    • C01B32/354After-treatment
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B32/00Carbon; Compounds thereof
    • C01B32/30Active carbon
    • C01B32/354After-treatment
    • C01B32/378Purification
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/16Cyclodextrin; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00Applications
    • C08L2203/02Applications for biomedical use

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a composiciones de ciclodextrina alquiladas bajas en cloruro, junto con procesos para preparar y utilizar las mismas. Los procesos de la presente invención proporcionan ciclodextrinas alquiladas con bajos niveles de agentes degradantes de fármacos y cloruro.
MX2014010323A 2012-02-28 2013-02-27 Composiciones de ciclodextrina alquilada y procesos para preparar y utilizar las mismas. MX353603B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261604504P 2012-02-28 2012-02-28
PCT/US2013/028094 WO2013130666A1 (en) 2012-02-28 2013-02-27 Alkylated cyclodextrin compositions and processes for preparing and using the same

Publications (2)

Publication Number Publication Date
MX2014010323A true MX2014010323A (es) 2014-12-08
MX353603B MX353603B (es) 2018-01-19

Family

ID=49083249

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018000787A MX390762B (es) 2012-02-28 2013-02-27 Composiciones de ciclodextrina alquilada y procesos para preparar y utilizar las mismas
MX2014010323A MX353603B (es) 2012-02-28 2013-02-27 Composiciones de ciclodextrina alquilada y procesos para preparar y utilizar las mismas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2018000787A MX390762B (es) 2012-02-28 2013-02-27 Composiciones de ciclodextrina alquilada y procesos para preparar y utilizar las mismas

Country Status (11)

Country Link
US (2) US9493582B2 (es)
EP (1) EP2748205A4 (es)
JP (3) JP2015508846A (es)
KR (3) KR20160033795A (es)
CN (2) CN110066351B (es)
AU (2) AU2013226073B2 (es)
CA (1) CA2865950C (es)
HK (1) HK1211311A1 (es)
MX (2) MX390762B (es)
RU (2) RU2615385C2 (es)
WO (1) WO2013130666A1 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090175810A1 (en) 2008-01-03 2009-07-09 Gareth Winckle Compositions and methods for treating diseases of the nail
US7635773B2 (en) 2008-04-28 2009-12-22 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions
AU2009308516B2 (en) 2008-10-21 2016-08-25 Onyx Therapeutics, Inc. Combination therapy with peptide epoxyketones
US8039494B1 (en) 2010-07-08 2011-10-18 Dow Pharmaceutical Sciences, Inc. Compositions and methods for treating diseases of the nail
PT3702374T (pt) 2012-02-15 2022-06-23 Cydex Pharmaceuticals Inc Processo de fabrico para derivados de ciclodextrina
MX390762B (es) 2012-02-28 2025-03-19 Cydex Pharmaceuticals Inc Composiciones de ciclodextrina alquilada y procesos para preparar y utilizar las mismas
SG10201609318UA (en) 2012-05-08 2016-12-29 Onyx Therapeutics Inc Cyclodextrin complexation methods for formulating peptide proteasome inhibitors
SG11201503089WA (en) 2012-10-22 2015-05-28 Cydex Pharmaceuticals Inc Alkylated cyclodextrin compositions and processes for preparing and using the same
AU2014329421B2 (en) 2013-10-03 2018-08-02 Dow Pharmaceutical Sciences, Inc. Stabilized efinaconazole compositions
KR20160087898A (ko) 2013-11-22 2016-07-22 다우 파마슈티컬 사이언시즈, 인코포레이티드 항­감염 방법,조성물,및 장치
CN103694376B (zh) 2014-01-10 2016-04-13 凯莱英医药集团(天津)股份有限公司 一种制备磺丁基醚-β-环糊精的方法
EP3183295B1 (en) 2014-08-22 2023-08-02 CyDex Pharmaceuticals, Inc. Fractionated alkylated cyclodextrin compositions and processes for preparing and using the same
US10532065B2 (en) 2014-12-19 2020-01-14 Nagasaki University Bisphosphonic acid derivative and application for same
CN105016334A (zh) * 2015-08-22 2015-11-04 钱景 一种烷基化环糊精还原氧化石墨烯的方法
FR3042501B1 (fr) * 2015-10-16 2017-11-03 Roquette Freres Nouvelles cyclodextrines methylees et leurs procedes de preparation
KR20180111948A (ko) 2016-02-18 2018-10-11 멜린타 테라퓨틱스, 인크. 오리타반신 제제
CN110167543A (zh) 2016-09-16 2019-08-23 锡德克斯药物公司 包含对乙酰氨基酚和磺烷基醚环糊精的制剂
WO2019053611A1 (en) 2017-09-14 2019-03-21 Glaxosmithkline Intellectual Property Development Limited POLY THERAPY FOR THE TREATMENT OF CANCER
US11147754B2 (en) 2017-09-20 2021-10-19 Kao Corporation Powder composition comprising hair direct dyes
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
EP3766475A1 (en) 2019-07-15 2021-01-20 OP-Hygiene IP GmbH Wipes
WO2021101842A1 (en) * 2019-11-18 2021-05-27 Cydex Pharmaceuticals, Inc. Alkylated cyclodextrin compositions and processes for preparing and using the same
DE102019133243A1 (de) * 2019-12-05 2021-06-10 Rheinische Friedrich-Wilhelms-Universität Bonn Verfahren zur Herstellung sprühgefriergetrockneter Partikel und entsprechend hergestellte Partikel
EP4134068A4 (en) * 2020-04-09 2024-02-07 Bika Biotechnology (Guangzhou) Co., Ltd. Bendamustine composition and use thereof
EP4217404A4 (en) * 2020-09-24 2024-10-09 CyDex Pharmaceuticals, Inc. ALKYLATED CYCLODEXTRIN COMPOSITIONS AND METHODS OF PREPARATION AND USE THEREOF
JP2023549292A (ja) * 2020-10-27 2023-11-22 バイヨン・セラピューティクス・インコーポレイテッド アゾベンゼン光反応性化合物の製剤
CN113275306B (zh) * 2021-04-19 2022-09-23 龙岩市华研活性炭科技有限公司 动态旋流活性炭酸洗机
US11649299B2 (en) 2021-06-10 2023-05-16 Cyclolab Cyclodextrin Research And Development Laboratory Ltd. Purification of sulfobutylated cyclodextrins with specific ion exchange resins
WO2023220641A2 (en) 2022-05-11 2023-11-16 Juno Therapeutics, Inc. Methods and uses related to t cell therapy and production of same
US20250302954A1 (en) 2022-05-11 2025-10-02 Celgene Corporation Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
CN115166115B (zh) * 2022-07-20 2024-07-09 宁波工程学院 鱼肉中多种汞形态含量检测的样品前处理方法及检测方法
CN115505052B (zh) * 2022-08-23 2023-05-23 安徽普利药业有限公司 一种β-环糊精衍生物的制备方法
WO2024097905A1 (en) 2022-11-02 2024-05-10 Celgene Corporation Methods of treatment with t cell therapy and immunomodulatory agent maintenance therapy
EP4685151A1 (en) 2024-07-24 2026-01-28 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Proteasome inhibitor

Family Cites Families (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US472706A (en) 1892-04-12 Elias m
US2744938A (en) 1952-07-24 1956-05-08 Universal Oil Prod Co Removal of color impurities from organic compounds
US3033900A (en) 1958-03-25 1962-05-08 Pfanstiehl Lab Inc Method of preparing calcium glucoheptonate
US3459731A (en) 1966-12-16 1969-08-05 Corn Products Co Cyclodextrin polyethers and their production
US3426011A (en) 1967-02-13 1969-02-04 Corn Products Co Cyclodextrins with anionic properties
US3453257A (en) 1967-02-13 1969-07-01 Corn Products Co Cyclodextrin with cationic properties
US3453259A (en) 1967-03-22 1969-07-01 Corn Products Co Cyclodextrin polyol ethers and their oxidation products
JPS5953038B2 (ja) 1979-04-07 1984-12-22 メルシャン株式会社 サイクロデキストリンの製造法
NL8104410A (nl) 1981-09-24 1983-04-18 Proefstation Voor Aardappelver Werkwijze ter bereiding van cyclodextrine.
JPS5862152A (ja) 1981-10-08 1983-04-13 Microbial Chem Res Found N−〔4−(3−アミノプロピル)アミノブチル〕−2−(ω−グアニジノ脂肪酸アミド)−2−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法
EP0147685B1 (de) 1983-12-17 1989-04-26 Hoechst Aktiengesellschaft Ether des beta-Cyclodextrins und ein Verfahren zu ihrer Herstellung
US4727064A (en) 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
JPS61169149A (ja) 1985-01-22 1986-07-30 Nippon Mining Co Ltd 連続鋳造方法
US4597946A (en) 1985-04-30 1986-07-01 Uop Inc. Vertical tube reactor with serial downward flow through a plurality of sets of particulate containing tubes
US6407079B1 (en) 1985-07-03 2002-06-18 Janssen Pharmaceutica N.V. Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation
US4920214A (en) 1986-04-16 1990-04-24 American Maize-Products Company Process for producing modified cyclodextrins
US4738923A (en) 1986-05-20 1988-04-19 American Maize-Products Company Process for producing and separating cyclodextrins
EP0274259B1 (en) 1986-12-19 1994-02-16 Sankyo Company Limited New renin-inhibitory oligopeptides, their preparaton and their use
US5019562A (en) 1988-01-19 1991-05-28 The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation Growth inhibiting agent and the use thereof
US5135919A (en) 1988-01-19 1992-08-04 Children's Medical Center Corporation Method and a pharmaceutical composition for the inhibition of angiogenesis
US5760015A (en) 1988-01-19 1998-06-02 The Trustees Of The University Of Pennsylvania Cyclodextrin compounds and methods of making and use thereof
US5183809A (en) 1990-02-15 1993-02-02 The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation Cyclodextrin polymers and cyclodextrins immobilized on a solid surface
US5658894A (en) 1989-04-23 1997-08-19 The Trustees Of The University Of Pennsylvania Compositions for inhibiting restenosis
US4904306A (en) 1988-07-22 1990-02-27 American Maize-Products Company Separation and purification of gamma cyclodextrin
US5173481A (en) 1989-04-03 1992-12-22 The United States Of America As Represented By The Department Of Health And Human Services Preparation of specifically substituted cyclodextrins
KR0163440B1 (ko) 1989-04-03 1998-11-16 디르크 반테 사이클로덱스트린의 위치선택적 치환 방법
US5257985A (en) 1989-12-04 1993-11-02 Richard Puhl Multi-chamber intravenous bag apparatus
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
US5241059A (en) 1990-05-21 1993-08-31 Toppan Printing Co., Ltd. Cyclodextrin derivatives
JP2905573B2 (ja) 1990-06-28 1999-06-14 日本食品化工株式会社 ヒドロキシアルキル化シクロデキストリン精製物及びその製造法
FR2668163B1 (fr) 1990-10-18 1993-01-15 Orsan Procede de fabrication de beta-cyclodextrine.
JPH051102A (ja) 1991-05-29 1993-01-08 Toppan Printing Co Ltd シクロデキストリン誘導体
CN1072185A (zh) 1991-11-13 1993-05-19 美国玉米产品公司 制备非混浊型环糊精的方法
US5324718A (en) 1992-07-14 1994-06-28 Thorsteinn Loftsson Cyclodextrin/drug complexation
US5472954A (en) 1992-07-14 1995-12-05 Cyclops H.F. Cyclodextrin complexation
DE69322721T2 (de) 1992-09-24 1999-06-10 Terumo K.K., Tokio/Tokyo Sulfonierte Verbindungen aus Beta-Cyclodextrinpolymer und diese enthaltendes Medikament welches die Hyperplasie von Gefässwanden hemmt
FR2705963B1 (fr) 1993-06-03 1995-07-13 Commissariat Energie Atomique Dérivés sulfonés de cyclomalto-oligosaccharides, leur procédé de préparation et support de substances actives contenant ces dérivés.
US5393880A (en) 1993-06-17 1995-02-28 American Maize-Products Company Cyclodextrin refining process
DE4333598A1 (de) 1993-10-01 1995-04-06 Consortium Elektrochem Ind Verfahren zur Herstellung von alkylierten Cyclodextrin-Derivaten, nach dem Verfahren herstellbare methylierte Cyclodextrin-Derivate und die Verwendung der Produkte
US5479254A (en) 1993-10-22 1995-12-26 Woskov; Paul P. Continuous, real time microwave plasma element sensor
US5661151A (en) 1993-12-21 1997-08-26 Schering Corporation Tetrahydrofuran antifungals
DE4401618A1 (de) 1994-01-20 1995-07-27 Consortium Elektrochem Ind Verfahren zur Herstellung von aminofunktionellen Cyclodextrin Derivaten
US5658390A (en) 1994-06-29 1997-08-19 American Maize-Products Company Purification of beta cyclodextrin
DE4428654A1 (de) 1994-08-12 1996-02-15 Consortium Elektrochem Ind Wasserlösliche Cyclodextrinderivate mit lipophilen Substituenten und Verfahren zu ihrer Herstellung
US5550222A (en) 1994-12-14 1996-08-27 American Maize-Products Company Process for producing gamma-cyclodextrin
DE4446891A1 (de) 1994-12-27 1996-07-04 Falk Pharma Gmbh Stabile wäßrige Budesonid-Lösung
DE19505263A1 (de) * 1995-02-16 1996-08-22 Consortium Elektrochem Ind Verfahren zur Reinigung von wasserlöslichen Cyclodextrinderivaten
US5569756A (en) 1995-03-21 1996-10-29 American Maize-Products Company Purification of chemically modified cyclodextrins
FR2735136B1 (fr) 1995-06-08 1997-08-14 Roquette Freres Composition pulverulente d'hydroxypropyl-betacyclodextrine et son procede de preparation.
US5935941A (en) 1997-10-24 1999-08-10 Pitha; Josef Alkylations of cyclodextrins leading to derivatives which have a ridgidly extended cavity
US5874418A (en) 1997-05-05 1999-02-23 Cydex, Inc. Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use
US6046177A (en) 1997-05-05 2000-04-04 Cydex, Inc. Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
US6033573A (en) 1997-05-29 2000-03-07 The United States Of America As Represented By The Secretary Of Agriculture Activated nutshell carbons from agricultural waste
US6133248A (en) 1997-06-13 2000-10-17 Cydex, Inc. Polar drug of prodrug compositions with extended shelf-life storage and a method of making thereof
ATE323110T1 (de) * 1997-07-01 2006-04-15 Pfizer Prod Inc Verfahren zur herstellung von einem cyclodextrin
US6316613B1 (en) 1997-07-25 2001-11-13 Beckman Coulter, Inc. Chiral separation of pharmaceutical compounds with charged cyclodextrins using capillary electrophoresis
ATE324122T1 (de) 1997-08-26 2006-05-15 Univ Texas Verwendung einer zusammensetzung die einen chelatbildner und eine antimikrobielle verbindung enthaltet zur behandlung von biofilmen
US6165484A (en) 1997-08-26 2000-12-26 Wake Forest University EDTA and other chelators with or without antifungal antimicrobial agents for the prevention and treatment of fungal infections
US6391862B1 (en) 1997-10-14 2002-05-21 The Texas A&M University System Chiral resolving agents for enantioseparations
AU1598399A (en) 1997-12-01 1999-06-16 Schering Corporation Injectable antifungal formulations
EP1067942A1 (en) 1998-02-23 2001-01-17 Cyclops, EHF. High-energy cyclodextrin complexes
TW394749B (en) 1998-03-05 2000-06-21 Deng Jian Lang Method of manufacturing active carbon by using carbon black
AT410321B (de) 1998-08-11 2003-03-25 Tulln Zuckerforschung Gmbh Verfahren zur herstellung von cyclodextrin
US6831099B1 (en) 1999-05-12 2004-12-14 Yale University Enzyme inhibition
DE19930553A1 (de) 1999-07-02 2001-01-11 Wacker Chemie Gmbh Verfahren zur Herstellung von alkylierten Cyclodextrin-Derivaten
TWI242015B (en) 1999-11-29 2005-10-21 Akzo Nobel Nv 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block
US6479467B1 (en) 1999-12-16 2002-11-12 Eastman Chemical Company Cyclodextrin ethers
FR2808691B1 (fr) 2000-05-12 2005-06-24 Coletica Cyclodextrines substituees preferentiellement sur leur face primaire par des fonctions acide ou amine
JP2005503446A (ja) 2001-01-11 2005-02-03 イーストマン ケミカル カンパニー シクロデキストリンスルホネート、ゲスト包接錯体、その製造方法及び関連物質
AU2002254309B2 (en) 2001-03-20 2006-02-02 Cydex, Inc. Formulations containing propofol and a sulfoalkyl ether cyclodextrin
US7034013B2 (en) 2001-03-20 2006-04-25 Cydex, Inc. Formulations containing propofol and a sulfoalkyl ether cyclodextrin
US6869939B2 (en) 2002-05-04 2005-03-22 Cydex, Inc. Formulations containing amiodarone and sulfoalkyl ether cyclodextrin
KR20050046776A (ko) 2002-09-13 2005-05-18 사이덱스 인크 유도체화된 사이클로덱스트린으로 안정화한 수성 충전조성물을 포함하는 캅셀
AU2004285032A1 (en) 2003-10-31 2005-05-12 The University Of Kansas Sulfoalkyl ether-alkyl ether cyclodextrin derivatives
US20070020196A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid prepared from a unit dose suspension
US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
US20070020298A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid
KR101725225B1 (ko) 2004-04-23 2017-04-12 사이덱스 파마슈티칼스, 인크. 술포알킬 에테르 시클로덱스트린 함유 dpi 제형
MXPA06012777A (es) 2004-05-06 2007-02-14 Cydex Inc Formulaciones de sabor enmascarado que contienen sertralina y eter sulfoalquilico-ciclodextrina.
US7559241B2 (en) 2004-05-27 2009-07-14 Sulphco, Inc. High-throughput continuous-flow ultrasound reactor
US20060009469A1 (en) 2004-05-28 2006-01-12 Leonore Witchey-Lakshmanan Particulate-stabilized injectable pharmacutical compositions of posaconazole
CN103374041B (zh) 2004-06-08 2017-05-10 症变治疗公司 路易斯酸介导的环状酯的合成
AU2005313975B2 (en) 2004-12-07 2012-09-06 Onyx Therapeutics, Inc. Composition for proteasome inhibition
US20060128653A1 (en) 2004-12-10 2006-06-15 Chunlin Tang Pharmaceutical formulation of decitabine
US20070082870A1 (en) 2005-10-11 2007-04-12 Buchanan Charles M Pharmaceutical formulations of cyclodextrins and antifungal azole compounds
HUE035181T2 (hu) 2005-10-26 2018-05-02 Cydex Pharmaceuticals Inc Szulfoalkil-éter-ciklodextrin kompozíciók és eljárások elõállításukra
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
CN100503647C (zh) 2005-11-02 2009-06-24 南京师范大学 羟丙基-磺丁基-β-环糊精及其制备方法、分析方法以及在药学上的应用
PT2061458E (pt) 2006-09-15 2015-03-11 Univ Minnesota Composições de topiramato e métodos para a sua utilização
US20090239942A1 (en) 2006-09-15 2009-09-24 Cloyd James C Topiramate Compositions and Methods of Making and Using the Same
CN101686681B (zh) * 2007-04-27 2015-04-01 锡德克斯药物公司 包含氯吡格雷和磺基烷基醚环糊精的制剂和其使用方法
EP1992334A1 (en) 2007-05-08 2008-11-19 Docpharma NV/SA Storage-stable formulation of oxidation-sensitive phenolic drug, especially paracetamol, comprises aqueous drug solution deoxygenated by a temperature-controlled manufacturing process of the formulation
US7834612B2 (en) * 2007-07-26 2010-11-16 Altronix Corporation Method and apparatus for regulating voltage in a remote device
EP2018866A1 (en) 2007-07-27 2009-01-28 Sandoz AG Pharmaceutical compositions containing voriconazole
WO2009018069A2 (en) * 2007-07-30 2009-02-05 Cydex Pharmaceuticals, Inc Mixtures of cyclodextrin derivatives
US7442830B1 (en) 2007-08-06 2008-10-28 Millenium Pharmaceuticals, Inc. Proteasome inhibitors
MY173938A (en) * 2007-10-04 2020-02-27 Onyx Therapeutics Inc Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides
EP2278957A2 (en) 2008-04-15 2011-02-02 Schering Corporation Oral pharmaceutical compositions in a solid dispersion comprising preferably posaconazole and hpmcas
US7635773B2 (en) * 2008-04-28 2009-12-22 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions
WO2010053487A1 (en) 2008-11-07 2010-05-14 Cydex Pharmaceuticals, Inc. Composition containing sulfoalkyl ether cyclodextrin and latanoprost
KR101912709B1 (ko) 2009-05-13 2018-10-30 사이덱스 파마슈티칼스, 인크. 프라수그렐 및 사이클로덱스트린 유도체를 포함하는 약학 조성물 및 그의 제조 및 사용 방법
CN106389307A (zh) 2009-05-29 2017-02-15 锡德克斯药物公司 包含环糊精衍生物的可注射美法仑组合物及其制备和使用方法
US8492538B1 (en) 2009-06-04 2013-07-23 Jose R. Matos Cyclodextrin derivative salts
CN102040675B (zh) 2010-12-22 2012-10-03 石药集团中诺药业(石家庄)有限公司 一种羟丙基-β-环糊精的制备方法
PT3702374T (pt) 2012-02-15 2022-06-23 Cydex Pharmaceuticals Inc Processo de fabrico para derivados de ciclodextrina
MX390762B (es) 2012-02-28 2025-03-19 Cydex Pharmaceuticals Inc Composiciones de ciclodextrina alquilada y procesos para preparar y utilizar las mismas
SG11201503089WA (en) 2012-10-22 2015-05-28 Cydex Pharmaceuticals Inc Alkylated cyclodextrin compositions and processes for preparing and using the same
EP3183295B1 (en) 2014-08-22 2023-08-02 CyDex Pharmaceuticals, Inc. Fractionated alkylated cyclodextrin compositions and processes for preparing and using the same
CN104892797B (zh) 2015-05-28 2017-03-22 天津大学 特定平均取代度磺丁基醚‑β‑环糊精的合成方法
CN104974275A (zh) 2015-07-30 2015-10-14 淄博千汇生物科技有限公司 磺烷基醚环糊精衍生物的合成方法

Also Published As

Publication number Publication date
JP2015508846A (ja) 2015-03-23
JP2016166368A (ja) 2016-09-15
AU2013226073B2 (en) 2016-05-05
CN110066351A (zh) 2019-07-30
KR101633479B1 (ko) 2016-07-08
EP2748205A4 (en) 2014-07-30
AU2013226073A1 (en) 2014-10-02
RU2016140391A3 (es) 2020-02-21
HK1211311A1 (en) 2016-05-20
AU2016210707A1 (en) 2016-08-25
CN110066351B (zh) 2022-06-14
RU2016140391A (ru) 2018-12-14
US10323103B2 (en) 2019-06-18
CN104704007A (zh) 2015-06-10
CA2865950C (en) 2016-12-20
JP6517725B2 (ja) 2019-05-22
JP2018048350A (ja) 2018-03-29
RU2014136206A (ru) 2016-04-20
RU2615385C2 (ru) 2017-04-04
US20150045311A1 (en) 2015-02-12
EP2748205A1 (en) 2014-07-02
KR20150004797A (ko) 2015-01-13
AU2016210707B2 (en) 2018-03-08
MX353603B (es) 2018-01-19
RU2747757C2 (ru) 2021-05-13
CA2865950A1 (en) 2013-09-06
WO2013130666A1 (en) 2013-09-06
US20170158781A1 (en) 2017-06-08
KR20200106100A (ko) 2020-09-10
MX390762B (es) 2025-03-19
KR20160033795A (ko) 2016-03-28
US9493582B2 (en) 2016-11-15

Similar Documents

Publication Publication Date Title
MX2014010323A (es) Composiciones de ciclodextrina alquilada y procesos para preparar y utilizar las mismas.
PH12015500887A1 (en) Alkylated cyclodextrin compositions and processes for preparing and using the same
IN2015DN00127A (es)
MX2015008999A (es) Inhibidores mk2 y usos de los mismos.
PH12014502602B1 (en) Methods for improving safety of blood-brain barrier transport
MX2015013686A (es) Composiciones y metodos para potenciar la estabilidad microbiana.
MX2015015421A (es) Inhibidores de acetil-coa carboxilasa (acc) y usos de los mismos.
MX2015015417A (es) Inhibidores de acetil-coa carboxilasa (acc) y usos de los mismos.
MX2015006183A (es) Composicion lubricante.
MX2015007518A (es) Metodos para tratar el prurito.
AU2018253594A1 (en) Dihydroxyphenyl neurotransmitter compounds, compositions and methods
MX349282B (es) Polisulfuros de organosilicio reticulados.
MA39824A (fr) Composés azole amido-substitués
IN2014CH00151A (es)
PH12016501183A1 (en) Novel compound for treatment of severe hypoglycemia
UA117567C2 (uk) Композиція, яка стимулює лактацію, на основі фосфатидилсерину
PH12016501182A1 (en) Novel compound for treatment of severe hypoglycemia
PH12016501184A1 (en) Novel compound for treatment of severe hypoglycemia
MX2015009377A (es) Compuestos radiomarcados.
EA201591770A1 (ru) Таксоиды - принцип очистки для жидких наполнителей
UA106373C2 (ru) Применение поллентара как средства фригопротекторного действия
UA96060C2 (ru) Применение липофлавона как средства фригопротекторного действия
UA80618U (en) Use of n-steroylethanolamine as radiomodifier
UA72478U (ru) Применение полентара как средства фригопротекторного действия
UA96059C2 (ru) Применение липина как средства фригопротекторного действия

Legal Events

Date Code Title Description
FG Grant or registration