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MX2014010278A - Variantes de albumina. - Google Patents

Variantes de albumina.

Info

Publication number
MX2014010278A
MX2014010278A MX2014010278A MX2014010278A MX2014010278A MX 2014010278 A MX2014010278 A MX 2014010278A MX 2014010278 A MX2014010278 A MX 2014010278A MX 2014010278 A MX2014010278 A MX 2014010278A MX 2014010278 A MX2014010278 A MX 2014010278A
Authority
MX
Mexico
Prior art keywords
variants
albumin variants
relates
present
parent albumin
Prior art date
Application number
MX2014010278A
Other languages
English (en)
Inventor
Karen Ann Delahay
Original Assignee
Novozymes Biopharma Dk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2012/058206 external-priority patent/WO2012150319A1/en
Application filed by Novozymes Biopharma Dk As filed Critical Novozymes Biopharma Dk As
Publication of MX2014010278A publication Critical patent/MX2014010278A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Optics & Photonics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a variantes de una albúmina precursora, las variantes tienen vida media en plasma alterada en comparación con la albúmina precursora. La presente invención también se refiere a polinucleótidos que codifican las variantes; construcciones de ácidos nucleicos, vectores, y células huésped que comprenden los polinucleótidos; y a métodos para utilizar las variantes.
MX2014010278A 2012-03-16 2013-03-15 Variantes de albumina. MX2014010278A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP12160007 2012-03-16
PCT/EP2012/058206 WO2012150319A1 (en) 2011-05-05 2012-05-04 Albumin variants
EP12187326 2012-10-05
EP12191086 2012-11-02
EP12191854 2012-11-08
PCT/EP2013/055487 WO2013135896A1 (en) 2012-03-16 2013-03-15 Albumin variants

Publications (1)

Publication Number Publication Date
MX2014010278A true MX2014010278A (es) 2015-03-05

Family

ID=49160283

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014010278A MX2014010278A (es) 2012-03-16 2013-03-15 Variantes de albumina.

Country Status (14)

Country Link
US (3) US9944691B2 (es)
EP (2) EP2825556B1 (es)
JP (2) JP6441682B2 (es)
KR (1) KR20140136934A (es)
CN (1) CN104736559B (es)
AU (2) AU2013234299B2 (es)
BR (1) BR112014018679A2 (es)
CA (1) CA2861592A1 (es)
DK (1) DK2825556T3 (es)
ES (1) ES2664328T3 (es)
IL (1) IL233689A0 (es)
MX (1) MX2014010278A (es)
PL (1) PL2825556T3 (es)
WO (1) WO2013135896A1 (es)

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