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MX2014001282A - Oxazolidinona que contiene compuestos de dimero, composicones y metodos para elaborar y usar. - Google Patents

Oxazolidinona que contiene compuestos de dimero, composicones y metodos para elaborar y usar.

Info

Publication number
MX2014001282A
MX2014001282A MX2014001282A MX2014001282A MX2014001282A MX 2014001282 A MX2014001282 A MX 2014001282A MX 2014001282 A MX2014001282 A MX 2014001282A MX 2014001282 A MX2014001282 A MX 2014001282A MX 2014001282 A MX2014001282 A MX 2014001282A
Authority
MX
Mexico
Prior art keywords
methods
compositions
make
oxazolidinone
compound
Prior art date
Application number
MX2014001282A
Other languages
English (en)
Inventor
John Finn
D Keith Hester
Robert J Duguid
Original Assignee
Trius Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trius Therapeutics Inc filed Critical Trius Therapeutics Inc
Publication of MX2014001282A publication Critical patent/MX2014001282A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Formas de dosificación o composiciones farmacéuticas que comprenden un compuesto con la estructura de fórmula IV: (ver Fórmula) en donde n es un entero no negativo; en donde cada Z es una región que contiene oxazolidinona con actividad antibiótica in vivo al clivaje, en donde M es independientemente OR1 o NR1R2 en donde R1 y R2 son independientemente seleccionados del grupo que consiste de H, residuo hidrocarbilo opcionalmente sustituido o un catión farmacéuticamente aceptable; en donde el compuesto en la forma de dosificación o una composición farmacéutica está presente en una cantidad efectiva para el tratamiento o prevención de una infección antibacterial en un sujeto mamífero. Métodos de preparación y uso de las formas de dosificación o composiciones farmacéuticas también se describen.
MX2014001282A 2009-05-28 2014-01-30 Oxazolidinona que contiene compuestos de dimero, composicones y metodos para elaborar y usar. MX2014001282A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18195509P 2009-05-28 2009-05-28
US12/787,293 US8580767B2 (en) 2009-05-28 2010-05-25 Oxazolidinone containing dimer compounds, compositions and methods to make and use

Publications (1)

Publication Number Publication Date
MX2014001282A true MX2014001282A (es) 2014-06-10

Family

ID=42333294

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2011012544A MX2011012544A (es) 2009-05-28 2010-05-27 Oxazolidinona que contiene compuestos de dimero, composiciones y metodos para elaborar y usar.
MX2014001282A MX2014001282A (es) 2009-05-28 2014-01-30 Oxazolidinona que contiene compuestos de dimero, composicones y metodos para elaborar y usar.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2011012544A MX2011012544A (es) 2009-05-28 2010-05-27 Oxazolidinona que contiene compuestos de dimero, composiciones y metodos para elaborar y usar.

Country Status (13)

Country Link
US (2) US8580767B2 (es)
EP (1) EP2435051A1 (es)
JP (2) JP5785939B2 (es)
KR (1) KR101745511B1 (es)
CN (2) CN102497866B (es)
AU (1) AU2010254039B2 (es)
BR (1) BRPI1012047A2 (es)
CA (1) CA2769769A1 (es)
IL (2) IL216547A0 (es)
MX (2) MX2011012544A (es)
NZ (2) NZ620552A (es)
RU (2) RU2015122032A (es)
WO (1) WO2010138649A1 (es)

Families Citing this family (9)

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KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
SG10201702946RA (en) 2008-10-10 2017-05-30 Merck Sharp & Dohme Methods for preparing oxazolidinones and compositions containing them
UA114068C2 (xx) 2009-02-03 2017-04-25 Кристалічні частинки (r)-3-(4-(2-(2-метилтетразол-5-іл)піридин-5-іл)-3-фторфеніл)-5-гідроксиметилоксазолідин-2-ондиводеньфосфату
US8580767B2 (en) 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
WO2015158202A1 (zh) * 2014-04-18 2015-10-22 杭州普晒医药科技有限公司 一种噁唑烷酮类抗生素的晶型及制备方法、组合物和用途
WO2016063246A1 (en) * 2014-10-22 2016-04-28 Sun Pharmaceutical Industries Limited Crystalline form r of tedizolid phosphate
EP3723758A4 (en) 2017-12-13 2021-06-23 Merck Sharp & Dohme Corp. PHARMACEUTICAL COMPOSITIONS OF TEDICOLIDE PHOSPHATE
CN111825666B (zh) * 2019-04-23 2024-03-08 上海仕谱生物科技有限公司 二聚或多聚体形式的突变型idh抑制剂
US20230219941A1 (en) 2020-06-18 2023-07-13 Akagera Medicines, Inc. Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and methods of use thereof

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Also Published As

Publication number Publication date
CN102497866B (zh) 2014-09-17
RU2557910C2 (ru) 2015-07-27
IL239049A0 (en) 2015-07-30
IL216547A0 (en) 2012-02-29
IL239049A (en) 2017-07-31
NZ596602A (en) 2014-02-28
JP5785939B2 (ja) 2015-09-30
JP2012528182A (ja) 2012-11-12
MX2011012544A (es) 2012-02-28
AU2010254039A1 (en) 2011-12-15
BRPI1012047A2 (pt) 2019-09-24
CN103923122B (zh) 2016-08-24
CA2769769A1 (en) 2010-12-02
WO2010138649A1 (en) 2010-12-02
JP6010196B2 (ja) 2016-10-19
KR20120026568A (ko) 2012-03-19
CN102497866A (zh) 2012-06-13
CN103923122A (zh) 2014-07-16
US20140057874A1 (en) 2014-02-27
EP2435051A1 (en) 2012-04-04
JP2016026145A (ja) 2016-02-12
KR101745511B1 (ko) 2017-06-20
NZ620552A (en) 2015-08-28
US8580767B2 (en) 2013-11-12
RU2015122032A (ru) 2015-12-10
US20100305069A1 (en) 2010-12-02
AU2010254039B2 (en) 2016-03-03

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