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MX2013014564A - Piridin-2-amidas utiles como agonistas canabinoides 2 (cb2). - Google Patents

Piridin-2-amidas utiles como agonistas canabinoides 2 (cb2).

Info

Publication number
MX2013014564A
MX2013014564A MX2013014564A MX2013014564A MX2013014564A MX 2013014564 A MX2013014564 A MX 2013014564A MX 2013014564 A MX2013014564 A MX 2013014564A MX 2013014564 A MX2013014564 A MX 2013014564A MX 2013014564 A MX2013014564 A MX 2013014564A
Authority
MX
Mexico
Prior art keywords
pyridin
agonists
amides useful
amides
useful
Prior art date
Application number
MX2013014564A
Other languages
English (en)
Other versions
MX339992B (es
Inventor
Tanja Schulz-Gasch
Matthias Nettekoven
Mark Rogers-Evans
Caterina Bissantz
Uwe Grether
Paul Hebeisen
Atsushi Kimbara
Qingping Liu
Marco Prunotto
Stephan Roever
Christoph Ullmer
Zhiwei Wang
Wulun Yang
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2013014564A publication Critical patent/MX2013014564A/es
Publication of MX339992B publication Critical patent/MX339992B/es

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract

La invención se refiere a un compuesto de la fórmula (I) (Ver Formula) en la que de R1 a R4 tienen los significados definidos en la descripción y en las reivindicaciones. El compuesto de la fórmula (I) puede utilizarse como medicamento.
MX2013014564A 2011-06-10 2012-06-07 Piridin-2-amidas utiles como agonistas canabinoides 2 (cb2). MX339992B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2011075606 2011-06-10
PCT/EP2012/060785 WO2012168350A1 (en) 2011-06-10 2012-06-07 Pyridin- 2 -amides useful as cb2 agonists

Publications (2)

Publication Number Publication Date
MX2013014564A true MX2013014564A (es) 2014-03-21
MX339992B MX339992B (es) 2016-06-21

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MX2013014564A MX339992B (es) 2011-06-10 2012-06-07 Piridin-2-amidas utiles como agonistas canabinoides 2 (cb2).

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US (2) US9321727B2 (es)
EP (2) EP3072886B1 (es)
JP (3) JP5997265B2 (es)
KR (1) KR20140042848A (es)
CN (2) CN103608332B (es)
AR (1) AR086881A1 (es)
AU (2) AU2012266369B2 (es)
BR (1) BR112013031463A2 (es)
CA (1) CA2835745A1 (es)
CL (1) CL2013003486A1 (es)
CO (1) CO6811864A2 (es)
CR (1) CR20130616A (es)
CY (1) CY1117878T1 (es)
DK (2) DK3072886T3 (es)
EA (2) EA027247B1 (es)
EC (1) ECSP13013074A (es)
ES (2) ES2588327T3 (es)
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