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MX2013004127A - Polipeptidos con actividad permeasa. - Google Patents

Polipeptidos con actividad permeasa.

Info

Publication number
MX2013004127A
MX2013004127A MX2013004127A MX2013004127A MX2013004127A MX 2013004127 A MX2013004127 A MX 2013004127A MX 2013004127 A MX2013004127 A MX 2013004127A MX 2013004127 A MX2013004127 A MX 2013004127A MX 2013004127 A MX2013004127 A MX 2013004127A
Authority
MX
Mexico
Prior art keywords
polypeptides
permease activity
polypeptide
permease
activity
Prior art date
Application number
MX2013004127A
Other languages
English (en)
Inventor
Jacobus Thomas Pronk
Hendrik Wouter Wisselink
Paul Klaassen
Antonius Jeroen Adriaan Van Maris
Rene Marcel De Jong
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of MX2013004127A publication Critical patent/MX2013004127A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • C12N1/18Baker's yeast; Brewer's yeast
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • C12P7/08Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • C12P7/08Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • C12P7/10Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Polipéptidos que tienen una mutación en una o más posiciones correspondientes a T219 de la SEQ ID N°: 55, en donde el polipéptido tiene al menos un 50% de identidad de secuencia con la SEQ ID N°: 55 y en donde el polipéptido tiene actividad permeasa.
MX2013004127A 2010-10-13 2011-10-11 Polipeptidos con actividad permeasa. MX2013004127A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39261710P 2010-10-13 2010-10-13
EP10075710 2010-10-13
PCT/EP2011/067726 WO2012049173A1 (en) 2010-10-13 2011-10-11 Polypeptides with permease activity

Publications (1)

Publication Number Publication Date
MX2013004127A true MX2013004127A (es) 2013-05-20

Family

ID=43480439

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013004127A MX2013004127A (es) 2010-10-13 2011-10-11 Polipeptidos con actividad permeasa.
MX2013004121A MX2013004121A (es) 2010-10-13 2011-10-11 Celula de levadura fermentadora de pentosas y glucosa.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2013004121A MX2013004121A (es) 2010-10-13 2011-10-11 Celula de levadura fermentadora de pentosas y glucosa.

Country Status (16)

Country Link
US (2) US9353376B2 (es)
EP (2) EP2627765B1 (es)
JP (2) JP2013542724A (es)
KR (2) KR20140005883A (es)
CN (2) CN103154234B (es)
AR (3) AR083449A1 (es)
AU (2) AU2011315569C1 (es)
BR (2) BR112013009157A2 (es)
CA (2) CA2813531A1 (es)
DK (1) DK2627765T3 (es)
EA (2) EA201300455A1 (es)
ES (1) ES2629252T3 (es)
MX (2) MX2013004127A (es)
MY (1) MY160995A (es)
PL (1) PL2627765T3 (es)
WO (3) WO2012049170A2 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140005883A (ko) 2010-10-13 2014-01-15 디에스엠 아이피 어셋츠 비.브이. 투과효소 활성을 갖는 폴리펩티드
US10189892B2 (en) 2013-03-15 2019-01-29 Alderbio Holdings Llc Fermentation process for antibody production
EP3004146B1 (en) * 2013-06-05 2017-12-20 DSM IP Assets B.V. Polypeptides with permease activity
WO2014195380A1 (en) * 2013-06-05 2014-12-11 Dsm Ip Assets B.V. Polypeptides with permease activity
WO2014195379A1 (en) * 2013-06-05 2014-12-11 Dsm Ip Assets B.V. Polypeptides with permease activity
WO2014195381A2 (en) * 2013-06-05 2014-12-11 Dsm Ip Assets B.V. Polypeptides with permease activity
WO2014195521A2 (en) * 2013-12-18 2014-12-11 Dsm Ip Assets B.V. Polypeptides with permease activity
WO2015091757A1 (en) * 2013-12-19 2015-06-25 Dsm Ip Assets B.V. Polypeptides with permease activity
KR102277898B1 (ko) 2014-07-03 2021-07-15 삼성전자주식회사 산물 생산능이 향상된 효모 및 그를 이용한 산물을 생산하는 방법
WO2016062823A1 (en) 2014-10-22 2016-04-28 Butalco Gmbh Variants of gal2 transporter and their uses
BR112018002284A2 (pt) 2015-08-05 2018-12-11 Cargill Inc método de fermentação para produzir um bioproduto, levedura crabtree negativa geneticamente engenheirada e método para reduzir a produção de glicerol por uma levedura engenheirada
WO2017067698A1 (en) 2015-10-22 2017-04-27 Direvo Industrial Biotechnology Gmbh Method for producing a fermentation product
EP3416740B1 (en) 2016-02-19 2021-01-06 Intercontinental Great Brands LLC Processes to create multiple value streams from biomass sources
CN106222101B (zh) * 2016-07-27 2020-03-27 中国科学技术大学 高温下高效利用菊芋一步生产高纯果糖的耐高温菌株及应用
US11365417B2 (en) * 2017-09-12 2022-06-21 Bio Capital Holdings, LLC Biological devices and methods of use thereof to produce steviol glycosides
DK3710469T3 (da) * 2017-11-14 2022-02-21 Dsm Ip Assets Bv Polypeptider med forbedret transportspecificitet for arabinose
EP3746546A1 (en) 2018-02-01 2020-12-09 DSM IP Assets B.V. Yeast cell capable of simultaneously fermenting hexose and pentose sugars
CN111304228B (zh) * 2020-03-18 2022-02-22 中国热带农业科学院橡胶研究所 一种橡胶树线粒体型己糖激酶基因及其编码蛋白和应用
WO2023000243A1 (zh) * 2021-07-22 2023-01-26 深圳先进技术研究院 重组酵母生物转化生产葡萄糖的方法
CN116064262A (zh) * 2021-07-22 2023-05-05 深圳先进技术研究院 一种重组酵母生物转化生产葡萄糖及其衍生物的方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990014423A1 (en) 1989-05-18 1990-11-29 The Infergene Company Microorganism transformation
CA2063592C (en) 1989-07-07 2003-01-21 Marco L. F. Giuseppin Process for preparing a protein by a fungus transformed by multicopy integration of an expression vector
FR2679920A1 (fr) 1991-08-02 1993-02-05 Rhone Poulenc Rorer Sa Levures recombinantes hautement stables pour la production de proteines recombinantes, leur preparation et leur utilisation.
ATE238425T1 (de) 1993-07-23 2003-05-15 Dsm Nv Selektionmarker-genfreie rekombinante stämme: verfahren zur ihrer herstellung und die verwendung dieser stämme
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
CN1169961C (zh) 1997-04-11 2004-10-06 Dsm公司 基因转变作为工具用于构建重组的工业化丝状真菌
EP1953230A1 (en) 1998-05-19 2008-08-06 DSM IP Assets B.V. Improved in vivo production of cephalosporins
WO2000037671A2 (en) 1998-12-22 2000-06-29 Dsm N.V. Improved in vivo production of cephalosporins
BR0306740A (pt) * 2002-01-23 2004-12-28 Royal Nedalco B V Célula hospedeira transformada com um construto de ácido nucléico, molécula de ácido nucleico isolada, e, processos para a produção de etanol, e de um produto de fermentação
SE0202090D0 (sv) 2002-05-08 2002-07-04 Forskarpatent I Syd Ab A modifierd yeast consuming L-arabinose
CN1735691B (zh) 2002-05-30 2010-05-26 卡吉尔道有限责任公司 利用比氧吸收率作为过程控制的发酵方法
WO2004085627A1 (en) 2003-03-26 2004-10-07 Forskarpatent I Syd Ab New saccharomyces cerevisiae strains utilizing xylose
WO2005056786A2 (en) * 2003-12-05 2005-06-23 Wisconsin Alumni Research Foundation Sugar kinases with expanded substrate specificity and their use
EP1781772B1 (en) 2004-07-16 2016-09-28 DSM IP Assets B.V. Metabolic engineering of xylose fermenting eukaryotic cells
JP2008527985A (ja) 2005-01-24 2008-07-31 ディーエスエム アイピー アセッツ ビー.ブイ. 糸状菌細胞において目的の化合物を産生させるための方法
MX2009003501A (es) 2006-10-02 2009-04-16 Dsm Ip Assets Bv Ingenieria metabolica de celulas eucariotas que fermentan arabinosa.
WO2008086124A1 (en) 2007-01-03 2008-07-17 Vialogy Llc Multi parallax exploitation for omni-directional imaging electronic eye
WO2008121701A1 (en) 2007-03-30 2008-10-09 Cargill Inc. Metabolic engineering of yeasts for the production of 1-butanol
AU2008236563B2 (en) * 2007-04-09 2014-06-19 University Of Georgia Research Foundation, Inc. Substrate-selective co-fermentation process
US20100304454A1 (en) 2007-07-19 2010-12-02 Royal Nedalco B.V. Novel arabinose-fermenting eukaryotic cells
ES2407639T3 (es) 2008-02-04 2013-06-13 Toray Industries, Inc. Procedimiento de producción de ácido láctico por fermentación continua
US20110104736A1 (en) 2008-03-13 2011-05-05 Jacobus Thomas Pronk Selection of organisms capable of fermenting mixed substrates
DE102008029302B4 (de) 2008-06-19 2016-08-11 Insilico Biotechnology Ag Biotechnologische Herstellung von Acrylsäure
FR2934264B1 (fr) 2008-07-22 2012-07-20 Arkema France Fabrication d'esters de vinyle a partir de matieres renouvelables, esters de vinyle obtenus et utilisations
PL2367928T3 (pl) * 2008-12-24 2018-08-31 Dsm Ip Assets B.V. Geny izomerazy ksylozy i ich zastosowanie w fermentacji cukrów pentozowych
JP2012518437A (ja) * 2009-02-25 2012-08-16 インディアナ ユニバーシティ リサーチ アンド テクノロジー コーポレイション D−グルコースの存在下でペントース糖を代謝する酵母菌株を同定・使用するための材料及び方法
AU2010218139B2 (en) 2009-02-25 2012-11-01 Merck Sharp & Dohme Corp. Metabolic engineering of a galactose assimilation pathway in the glycoengineered yeast Pichia pastoris
KR20140005883A (ko) 2010-10-13 2014-01-15 디에스엠 아이피 어셋츠 비.브이. 투과효소 활성을 갖는 폴리펩티드

Also Published As

Publication number Publication date
WO2012049170A3 (en) 2012-06-14
WO2012049179A3 (en) 2012-06-14
PL2627765T3 (pl) 2017-10-31
EP2627767A1 (en) 2013-08-21
KR20130100169A (ko) 2013-09-09
AR083447A1 (es) 2013-02-27
AR083448A1 (es) 2013-02-27
AU2011315569B2 (en) 2015-09-24
CA2813513A1 (en) 2012-04-19
US9353376B2 (en) 2016-05-31
DK2627765T3 (en) 2017-08-28
WO2012049170A2 (en) 2012-04-19
US9034608B2 (en) 2015-05-19
AU2011315569A1 (en) 2013-04-11
BR112013009157A2 (pt) 2016-07-26
EP2627765B1 (en) 2017-05-10
AR083449A1 (es) 2013-02-27
KR20140005883A (ko) 2014-01-15
MY160995A (en) 2017-03-28
AU2011315572B2 (en) 2015-09-03
AU2011315572A1 (en) 2013-04-11
US20130236932A1 (en) 2013-09-12
WO2012049179A2 (en) 2012-04-19
AU2011315569C1 (en) 2016-02-04
WO2012049173A1 (en) 2012-04-19
CN103154234A (zh) 2013-06-12
EP2627765A2 (en) 2013-08-21
JP2013542724A (ja) 2013-11-28
EA201300454A1 (ru) 2013-09-30
ES2629252T3 (es) 2017-08-08
MX2013004121A (es) 2014-02-27
JP5961886B2 (ja) 2016-08-03
BR112013008981A2 (pt) 2017-10-03
CA2813531A1 (en) 2012-04-19
CN103154234B (zh) 2016-08-17
US20130273601A1 (en) 2013-10-17
EA201300455A1 (ru) 2013-09-30
JP2013539655A (ja) 2013-10-28
CN103189505A (zh) 2013-07-03

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