MX2012013362A - Una composicion farmaceutica de liberacion controlada de losartan. - Google Patents
Una composicion farmaceutica de liberacion controlada de losartan.Info
- Publication number
- MX2012013362A MX2012013362A MX2012013362A MX2012013362A MX2012013362A MX 2012013362 A MX2012013362 A MX 2012013362A MX 2012013362 A MX2012013362 A MX 2012013362A MX 2012013362 A MX2012013362 A MX 2012013362A MX 2012013362 A MX2012013362 A MX 2012013362A
- Authority
- MX
- Mexico
- Prior art keywords
- losartan
- controlled release
- release composition
- pharmaceutical controlled
- prophylaxis
- Prior art date
Links
- 239000002083 C09CA01 - Losartan Substances 0.000 title abstract 4
- KJJZZJSZUJXYEA-UHFFFAOYSA-N losartan Chemical group CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C=2[N]N=NN=2)C=C1 KJJZZJSZUJXYEA-UHFFFAOYSA-N 0.000 title abstract 4
- 229960004773 losartan Drugs 0.000 title abstract 4
- 238000013270 controlled release Methods 0.000 title abstract 3
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000000717 retained effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a una composición farmacéutica de liberación controlada de losartan que comprende un núcleo de retención gástrica con losartan y una cantidad comprendida entre 5 y 25% en peso de hidroxipropilmetilcelulosa como único polímero de liberación controlada, y una capa activa de liberación inmediata que contiene losartan, a su procedimiento de preparación y a su uso para la profilaxis y el tratamiento de la hipertensión.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10382135A EP2392318A1 (en) | 2010-05-21 | 2010-05-21 | A pharmaceutical controlled release composition of losartan |
| PCT/EP2011/058229 WO2011144724A1 (en) | 2010-05-21 | 2011-05-20 | A pharmaceutical controlled release composition of losartan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012013362A true MX2012013362A (es) | 2013-05-01 |
Family
ID=42635468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012013362A MX2012013362A (es) | 2010-05-21 | 2011-05-20 | Una composicion farmaceutica de liberacion controlada de losartan. |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP2392318A1 (es) |
| AR (1) | AR081400A1 (es) |
| BR (1) | BR112012029565A2 (es) |
| MX (1) | MX2012013362A (es) |
| TW (1) | TW201201800A (es) |
| UY (1) | UY33393A (es) |
| WO (1) | WO2011144724A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018002673A1 (en) * | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
| CN119112811A (zh) * | 2016-08-29 | 2024-12-13 | 北京科信聚润医药科技有限公司 | 一种氢氯噻嗪微片及其制备方法 |
| IT201800011123A1 (it) | 2018-12-14 | 2020-06-14 | Dpl Pharma S P A | Composizioni farmaceutiche orali solide per la somministrazione cronotropica di sartani |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1438027A1 (en) | 2001-10-25 | 2004-07-21 | DepoMed, Inc. | Methods of treatment using a gastric retained losartan dosage |
| KR100888131B1 (ko) * | 2006-10-10 | 2009-03-11 | 한올제약주식회사 | 시간차 투약 원리를 이용한 심혈관계 질환 치료용 복합제제 |
| EP2086519B1 (en) * | 2006-10-30 | 2017-06-21 | HanAll Biopharma Co., Ltd. | Controlled release complex composition comprising angiotensin-ii-receptor blockers and hmg-coa reductase inhibitors |
-
2010
- 2010-05-21 EP EP10382135A patent/EP2392318A1/en not_active Withdrawn
-
2011
- 2011-05-16 TW TW100117019A patent/TW201201800A/zh unknown
- 2011-05-17 UY UY0001033393A patent/UY33393A/es not_active Application Discontinuation
- 2011-05-17 AR ARP110101685A patent/AR081400A1/es not_active Application Discontinuation
- 2011-05-20 BR BR112012029565A patent/BR112012029565A2/pt not_active Application Discontinuation
- 2011-05-20 WO PCT/EP2011/058229 patent/WO2011144724A1/en not_active Ceased
- 2011-05-20 MX MX2012013362A patent/MX2012013362A/es active IP Right Grant
- 2011-05-20 EP EP11720522A patent/EP2571495A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011144724A1 (en) | 2011-11-24 |
| TW201201800A (en) | 2012-01-16 |
| AR081400A1 (es) | 2012-08-29 |
| BR112012029565A2 (pt) | 2016-12-13 |
| EP2571495A1 (en) | 2013-03-27 |
| UY33393A (es) | 2011-12-30 |
| EP2392318A1 (en) | 2011-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |