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MX2012013193A - Nuevo proceso para preparar aminas olefinicas sustituidas con arilo. - Google Patents

Nuevo proceso para preparar aminas olefinicas sustituidas con arilo.

Info

Publication number
MX2012013193A
MX2012013193A MX2012013193A MX2012013193A MX2012013193A MX 2012013193 A MX2012013193 A MX 2012013193A MX 2012013193 A MX2012013193 A MX 2012013193A MX 2012013193 A MX2012013193 A MX 2012013193A MX 2012013193 A MX2012013193 A MX 2012013193A
Authority
MX
Mexico
Prior art keywords
preparation
aryl substituted
new process
substituted olefinic
olefinic amines
Prior art date
Application number
MX2012013193A
Other languages
English (en)
Inventor
Gary Maurice Dull
John Genus
Tommi Ratilainen
Per Olof Ryberg
Janna Hellstroem
Niklas Wahlstroem
Thomas Waennman
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2012013193A publication Critical patent/MX2012013193A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01D—COMPOUNDS OF ALKALI METALS, i.e. LITHIUM, SODIUM, POTASSIUM, RUBIDIUM, CAESIUM, OR FRANCIUM
    • C01D15/00—Lithium compounds
    • C01D15/06—Sulfates; Sulfites
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/02—Crystallisation from solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/20—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C07C211/21—Monoamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Un proceso mejorado para preparar aminas olefínicas sustituidas con arilo, tales como (2S)-(4E)-N-metil-5-[3-(5-isopropoxipiridin) il]-4-penten-2-amina y (2S)-(4E)-N-metil-5-[3-(5-metoxipiridin)il] -4-penten-2-amina, y nuevos intermedios utilizados en el proceso.
MX2012013193A 2010-05-20 2011-05-19 Nuevo proceso para preparar aminas olefinicas sustituidas con arilo. MX2012013193A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34650410P 2010-05-20 2010-05-20
PCT/SE2011/050630 WO2011146009A1 (en) 2010-05-20 2011-05-19 New process for the preparation of aryl substituted olefinic amines

Publications (1)

Publication Number Publication Date
MX2012013193A true MX2012013193A (es) 2012-12-17

Family

ID=44991920

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012013193A MX2012013193A (es) 2010-05-20 2011-05-19 Nuevo proceso para preparar aminas olefinicas sustituidas con arilo.

Country Status (15)

Country Link
US (1) US8703802B2 (es)
EP (1) EP2574188A4 (es)
JP (1) JP2013528601A (es)
KR (1) KR20130081221A (es)
CN (1) CN103180277A (es)
AR (1) AR081405A1 (es)
AU (1) AU2011256866B2 (es)
BR (1) BR112012029326A2 (es)
CA (1) CA2799650A1 (es)
IL (1) IL222940A0 (es)
MX (1) MX2012013193A (es)
RU (1) RU2012150449A (es)
SG (1) SG185497A1 (es)
TW (1) TW201213287A (es)
WO (1) WO2011146009A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108715573A (zh) * 2018-08-02 2018-10-30 江西力田维康科技有限公司 一种3-丁烯-1-醇的制备方法
CN118063288A (zh) * 2022-11-24 2024-05-24 顺毅宜昌化工有限公司 一种芳基乙醇衍生物的制备方法

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Also Published As

Publication number Publication date
CN103180277A (zh) 2013-06-26
AU2011256866A1 (en) 2012-12-20
CA2799650A1 (en) 2011-11-24
IL222940A0 (en) 2012-12-31
WO2011146009A8 (en) 2012-01-19
EP2574188A1 (en) 2013-04-03
BR112012029326A2 (pt) 2017-08-08
EP2574188A4 (en) 2015-09-02
AU2011256866B2 (en) 2014-05-22
JP2013528601A (ja) 2013-07-11
SG185497A1 (en) 2012-12-28
US20130225827A1 (en) 2013-08-29
KR20130081221A (ko) 2013-07-16
WO2011146009A1 (en) 2011-11-24
TW201213287A (en) 2012-04-01
AR081405A1 (es) 2012-08-29
RU2012150449A (ru) 2014-06-27
US8703802B2 (en) 2014-04-22

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