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MX2012012004A - Proceso para preparar amidas de acidos carboxilicos pirazolicos. - Google Patents

Proceso para preparar amidas de acidos carboxilicos pirazolicos.

Info

Publication number
MX2012012004A
MX2012012004A MX2012012004A MX2012012004A MX2012012004A MX 2012012004 A MX2012012004 A MX 2012012004A MX 2012012004 A MX2012012004 A MX 2012012004A MX 2012012004 A MX2012012004 A MX 2012012004A MX 2012012004 A MX2012012004 A MX 2012012004A
Authority
MX
Mexico
Prior art keywords
formula
compound
reacting
preparation
carboxylic acid
Prior art date
Application number
MX2012012004A
Other languages
English (en)
Inventor
Thomas Vettiger
Denis Gribkov
Michael Rommel
Remo Stohler
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of MX2012012004A publication Critical patent/MX2012012004A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
    • C07C25/24—Halogenated aromatic hydrocarbons with unsaturated side chains

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)

Abstract

La invención se refiere a un proceso para preparar la fórmula (I) (Ver Formula) comprendiendo el proceso a) hacer reaccionar un compuesto de fórmula (II) (Ver Formula) (II), donde X es cloro o bromo, con una especie organometálica para obtener (III) (Ver Formula) (III), donde X es cloro o bromo; hacer reaccionar el halobencino con un fulveno (IV) (Ver Formula) (IV), para obtener un compuesto de fórmula (V) (Ver Formula) donde X es cloro o bromo; b) hidrogenar (V) en presencia de un catalizador metálico adecuado para obtener un compuesto de fórmula (VI) (Ver Formula) (VI), donde X es cloro o bromo; y o bien (i) hacer reaccionar el compuesto de fórmula (VI) con NH3 en presencia de un catalizador que comprenda paladio y al menos un ligando para obtener el compuesto de fórmula (VII) (Ver Formula) (VII); y d) hacer reaccionar el compuesto de fórmula (VII) en presencia de una base con un compuesto de fórmula (VIII) (Ver Formula) (VIII), para obtener el compuesto de fórmula (I); o bien c2) hacer reaccionar el compuesto de fórmula (VI) en presencia de un catalizador de cobre y un ligando con el compuesto de fórmula (VIIIa) (Ver Formula) (Villa), para obtener el compuesto de fórmula (1).
MX2012012004A 2010-04-20 2011-04-14 Proceso para preparar amidas de acidos carboxilicos pirazolicos. MX2012012004A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10160437 2010-04-20
PCT/EP2011/055872 WO2011131546A1 (en) 2010-04-20 2011-04-14 Process for the preparation of pyrazole carboxylic acid amides

Publications (1)

Publication Number Publication Date
MX2012012004A true MX2012012004A (es) 2012-12-17

Family

ID=44070080

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012012004A MX2012012004A (es) 2010-04-20 2011-04-14 Proceso para preparar amidas de acidos carboxilicos pirazolicos.

Country Status (12)

Country Link
US (1) US8519151B2 (es)
EP (1) EP2560958B1 (es)
JP (1) JP5684897B2 (es)
CN (1) CN102844306B (es)
AR (1) AR080921A1 (es)
BR (1) BR112012026752B1 (es)
ES (1) ES2453919T3 (es)
IL (1) IL222401A (es)
MX (1) MX2012012004A (es)
TW (1) TWI428324B (es)
UY (1) UY33339A (es)
WO (1) WO2011131546A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102858749B (zh) * 2010-04-20 2014-07-02 先正达参股股份有限公司 吡唑羧酸酰胺的制备方法
EP2433922A1 (en) * 2010-08-25 2012-03-28 Syngenta Participations AG Process for the preparation of dichlorofulvene
TWI534126B (zh) 2011-01-25 2016-05-21 先正達合夥公司 用於製備吡唑羧酸醯胺之方法
CN103483407B (zh) * 2013-10-10 2015-11-18 宁夏启元药业有限公司 一种硫氰酸红霉素萃取结晶用复合溶媒及萃取结晶方法
GB201403438D0 (en) * 2014-02-27 2014-04-16 Syngenta Participations Ag Polymorphs
CN111138364A (zh) * 2018-11-01 2020-05-12 东莞市东阳光菌阳氢专利农药有限公司 一种氟苯醚酰胺的制备方法
EP4558484A1 (en) 2022-07-22 2025-05-28 Syngenta Crop Protection AG Solid form of a heterocyclic amide derivative
CN116143635B (zh) * 2022-12-01 2025-02-25 江苏七洲绿色科技研究院有限公司 一种9-二氯亚甲基-5-氨基-苯并降冰片烯的制备方法
CN117362179B (zh) * 2023-09-22 2025-07-08 浙江工业大学 一种苯并烯氟菌唑中间体9-二氯亚甲基-1,4-二氢-5-硝基-1,4-甲桥萘的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH075487B2 (ja) 1985-11-14 1995-01-25 住友化学工業株式会社 １―ブロモ―２―クロロ―４―フルオロベンゼンの製造法
US5093347A (en) 1991-01-28 1992-03-03 Monsanto Company 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use
US7223879B2 (en) 1998-07-10 2007-05-29 Massachusetts Institute Of Technology Ligands for metals and improved metal-catalyzed processes based thereon
CA2626312C (en) * 2005-10-25 2014-10-07 Hans Tobler Heterocyclic amide derivatives useful as microbiocides
WO2007124907A2 (en) * 2006-04-27 2007-11-08 Syngenta Participations Ag Heterocyclyl-carboxylic acid (benzonorbornene-5-yl)amide derivatives as fungicides for agrochemical use
WO2007129736A1 (ja) * 2006-05-10 2007-11-15 Idemitsu Kosan Co., Ltd. ジシクロペンタジエンの製造方法
ATE511350T1 (de) 2006-10-25 2011-06-15 Syngenta Ltd Verfahren für die herstellung von substituierten brombenzolen
JP5406302B2 (ja) * 2008-10-27 2014-02-05 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト ベンゾノルボルネンの製造方法
EP2373625B1 (en) * 2008-12-24 2014-10-08 Syngenta Limited Methods for the preparation of aryl amides

Also Published As

Publication number Publication date
EP2560958A1 (en) 2013-02-27
BR112012026752A2 (pt) 2015-09-15
AR080921A1 (es) 2012-05-16
UY33339A (es) 2011-12-01
JP5684897B2 (ja) 2015-03-18
ES2453919T3 (es) 2014-04-08
CN102844306B (zh) 2015-01-14
IL222401A (en) 2015-04-30
US20130035495A1 (en) 2013-02-07
US8519151B2 (en) 2013-08-27
TW201204703A (en) 2012-02-01
JP2013527841A (ja) 2013-07-04
WO2011131546A1 (en) 2011-10-27
CN102844306A (zh) 2012-12-26
TWI428324B (zh) 2014-03-01
BR112012026752B1 (pt) 2018-02-06
EP2560958B1 (en) 2014-01-01

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