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MX2012010528A - Composicion farmaceutica con actividad antimicrobiana y antiinflamatoria para administracion parenteral y procedimiento de produccion de la misma. - Google Patents

Composicion farmaceutica con actividad antimicrobiana y antiinflamatoria para administracion parenteral y procedimiento de produccion de la misma.

Info

Publication number
MX2012010528A
MX2012010528A MX2012010528A MX2012010528A MX2012010528A MX 2012010528 A MX2012010528 A MX 2012010528A MX 2012010528 A MX2012010528 A MX 2012010528A MX 2012010528 A MX2012010528 A MX 2012010528A MX 2012010528 A MX2012010528 A MX 2012010528A
Authority
MX
Mexico
Prior art keywords
pharmaceutical composition
preparing
parenteral administration
antimicrobial
silicon dioxide
Prior art date
Application number
MX2012010528A
Other languages
English (en)
Inventor
Viktor Lvovich Limonov
Konstantin Valentinovich Gaidul
Aleksandr Valerevich Dushkin
Original Assignee
Viktor Lvovich Limonov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viktor Lvovich Limonov filed Critical Viktor Lvovich Limonov
Publication of MX2012010528A publication Critical patent/MX2012010528A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a farmacología, medicina, veterinaria e industria farmacéutica. Se refiere en particular al procedimiento de producción de preparaciones antimicrobianas compuestas originales para administración parenteral, que presentan una eficacia terapéutica superior en el caso de enfermedades infecciosas e inflamatorias graves. Los agentes activos de las composiciones farmacéuticas propuestas son fosfomicina y dióxido de silicio nanoestructurado finamente disperso. Dicho procedimiento de producción de composición farmacéutica incluye mezclar fosfomicina con dióxido de silicio nanoestructurado finamente disperso. Se caracteriza principalmente porque dicha mezcla de sustancias con una razón en peso de desde 10:1 hasta 75:1, respectivamente, se expone a procesamiento mecánico mediante operaciones de abrasión por impacto hasta que aumenta la proporción en peso de la fracción de polvo fino (< 5 micrómetros) y pasa a ser no inferior al 25%. La mezcla obtenida se usa para la preparación de inyecciones.
MX2012010528A 2010-09-20 2011-05-11 Composicion farmaceutica con actividad antimicrobiana y antiinflamatoria para administracion parenteral y procedimiento de produccion de la misma. MX2012010528A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EA201001507A EA021876B1 (ru) 2010-09-20 2010-09-20 Фармацевтическая композиция антимикробного и противовоспалительного действия для парентерального введения, способ ее получения
PCT/RU2011/000321 WO2012039641A1 (ru) 2010-09-20 2011-05-11 Фармацевтическая композиция антимикробного и противовоспалительного действия для парентерального введения, способ её получения

Publications (1)

Publication Number Publication Date
MX2012010528A true MX2012010528A (es) 2012-12-17

Family

ID=45874027

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012010528A MX2012010528A (es) 2010-09-20 2011-05-11 Composicion farmaceutica con actividad antimicrobiana y antiinflamatoria para administracion parenteral y procedimiento de produccion de la misma.

Country Status (11)

Country Link
US (1) US20130164336A1 (es)
EP (1) EP2476419A4 (es)
JP (1) JP2013537226A (es)
CN (1) CN102740858A (es)
AU (1) AU2011304261C1 (es)
BR (1) BR112012023963A2 (es)
CA (1) CA2780785A1 (es)
EA (1) EA021876B1 (es)
MX (1) MX2012010528A (es)
UA (1) UA103116C2 (es)
WO (1) WO2012039641A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2476206C1 (ru) * 2011-11-22 2013-02-27 Виктор Львович Лимонов Фармацевтическая композиция для приготовления инфузионных растворов антимикробных препаратов, способ ее получения (варианты)
EP3219305A1 (de) 2016-03-16 2017-09-20 Apostolos Georgopoulos Fosfomycin-formulierung zur parenteralen verabreichung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2179944A (en) * 1985-09-03 1987-03-18 Espan Penicilin & Antibioticos Mixtures of mono- and disodium salts of fosfomycin
ITMI20021725A1 (it) * 2002-08-01 2002-10-31 Zambon Spa Composizioni farmaceutiche ad attivita' antibiotica.
ES2244333B1 (es) * 2004-05-18 2006-08-01 Simbec Iberica, Sl Preparado farmaceutico oral de fosfomicina estable y apto para diabeticos.

Also Published As

Publication number Publication date
CN102740858A (zh) 2012-10-17
EP2476419A4 (en) 2013-07-17
EA021876B1 (ru) 2015-09-30
WO2012039641A1 (ru) 2012-03-29
AU2011304261B2 (en) 2012-06-28
JP2013537226A (ja) 2013-09-30
CA2780785A1 (en) 2012-03-29
AU2011304261A8 (en) 2012-07-05
AU2011304261C1 (en) 2012-11-29
EP2476419A1 (en) 2012-07-18
EA201001507A1 (ru) 2012-02-28
BR112012023963A2 (pt) 2016-08-02
AU2011304261A1 (en) 2012-04-19
US20130164336A1 (en) 2013-06-27
UA103116C2 (ru) 2013-09-10
AU2011304261B8 (en) 2012-07-05

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal