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MX2012010084A - Compuestos utiles para tratar transtornos neurodegenerativos. - Google Patents

Compuestos utiles para tratar transtornos neurodegenerativos.

Info

Publication number
MX2012010084A
MX2012010084A MX2012010084A MX2012010084A MX2012010084A MX 2012010084 A MX2012010084 A MX 2012010084A MX 2012010084 A MX2012010084 A MX 2012010084A MX 2012010084 A MX2012010084 A MX 2012010084A MX 2012010084 A MX2012010084 A MX 2012010084A
Authority
MX
Mexico
Prior art keywords
compounds useful
neurodegenerative disorders
treating neurodegenerative
treating
lessening
Prior art date
Application number
MX2012010084A
Other languages
English (en)
Inventor
Brian Scott Bronk
Steffen Phillip Creaser
Wesley Francis Austin
Mark Arthur Findeis
Nathan Oliver Fuller
Jed Lee Hubbs
Jeffrey Lee Ives
Ruichao Shen
Original Assignee
Satori Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Satori Pharmaceuticals Inc filed Critical Satori Pharmaceuticals Inc
Publication of MX2012010084A publication Critical patent/MX2012010084A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07GCOMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G3/00Glycosides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036Nitrogen-containing hetero ring
    • C07J71/0057Nitrogen and oxygen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

La invención se refiere a compuestos que resulta de utilidad para tratar o atenuar la gravedad de un trastorno neurodegenerativo. La presente invención también se refiere s un método para tratar o atenuar la gravedad de los trastornos, donde el método comprende administrarle aun paciente un compuesto de la presente invención o una composición de éste. El método resulta de utilidad para tratar o atenuar la gravedad de, por ejemplo, el mal de Alzheirme.
MX2012010084A 2010-03-03 2011-03-03 Compuestos utiles para tratar transtornos neurodegenerativos. MX2012010084A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31015210P 2010-03-03 2010-03-03
PCT/US2011/027084 WO2011109657A1 (en) 2010-03-03 2011-03-03 Compounds useful for treating neurodegenerative disorders

Publications (1)

Publication Number Publication Date
MX2012010084A true MX2012010084A (es) 2013-01-18

Family

ID=44542588

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012010084A MX2012010084A (es) 2010-03-03 2011-03-03 Compuestos utiles para tratar transtornos neurodegenerativos.

Country Status (14)

Country Link
US (1) US20110251379A1 (es)
EP (1) EP2542085A4 (es)
JP (1) JP2013521307A (es)
KR (1) KR20120136378A (es)
CN (1) CN102939011A (es)
AR (1) AR080455A1 (es)
AU (1) AU2011223542A1 (es)
BR (1) BR112012022224A2 (es)
CA (1) CA2790060A1 (es)
IL (1) IL221415A0 (es)
MX (1) MX2012010084A (es)
RU (1) RU2012135118A (es)
TW (1) TW201134476A (es)
WO (1) WO2011109657A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR087789A1 (es) * 2011-09-07 2014-04-16 Satori Pharmaceuticals Inc Metodos para la sintesis de compuestos utiles para tratar trastornos neurodegenerativos y para obtener compuestos intermedios de los mismos
TW201317257A (zh) * 2011-09-07 2013-05-01 Satori Pharmaceuticals Inc 用於治療神經退化性病症之化合物
CN105246486B (zh) * 2013-03-13 2020-11-03 萨奇治疗股份有限公司 神经活性甾类化合物
KR101472916B1 (ko) * 2013-06-27 2014-12-16 한국과학기술연구원 모르폴린 또는 피페라진 화합물, 및 도네페질을 포함하는 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물
CN108426999B (zh) * 2017-02-15 2020-10-23 江苏美正生物科技有限公司 一种金刚烷胺残留的快速检测试剂盒及其制备方法和应用
DE102017008073A1 (de) * 2017-08-28 2019-02-28 Henkel Ag & Co. Kgaa Neue anionische Tenside und Wasch- und Reinigungsmittel, welche diese enthalten
CN112457362B (zh) * 2019-09-06 2023-09-19 上海青东生物科技有限公司 一种卤代四环三萜衍生物及其制备与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9600229D0 (sv) * 1996-01-23 1996-01-23 Pharmacia Ab Novel potentiating agents
US20070149491A1 (en) * 2005-05-17 2007-06-28 Findeis Mark A Compounds useful for treating neurodegenerative disorders
NZ563888A (en) * 2005-05-17 2009-11-27 Satori Pharmaceuticals Inc Compounds isolated from black cohosh root that are useful for treating neurodegenerative disorders by inhibiting amyloid-beta peptide production
NZ577081A (en) * 2006-11-20 2012-11-30 Satori Pharmaceuticals Inc Synthesis of compounds useful as modulators of amyloid-beta production
CN101339167B (zh) * 2008-08-27 2011-12-14 中国药科大学 基于靶蛋白亲和选择的活性成分高通量筛选方法
EP2438921A1 (en) * 2010-10-11 2012-04-11 Universität Innsbruck 23-O-Acetylshengmanol-3-O-beta-D-xylopyranoside and its medical use

Also Published As

Publication number Publication date
EP2542085A4 (en) 2013-12-04
US20110251379A1 (en) 2011-10-13
JP2013521307A (ja) 2013-06-10
BR112012022224A2 (pt) 2016-08-23
WO2011109657A1 (en) 2011-09-09
CA2790060A1 (en) 2011-09-09
AR080455A1 (es) 2012-04-11
TW201134476A (en) 2011-10-16
KR20120136378A (ko) 2012-12-18
IL221415A0 (en) 2012-10-31
RU2012135118A (ru) 2014-04-10
EP2542085A1 (en) 2013-01-09
CN102939011A (zh) 2013-02-20
AU2011223542A1 (en) 2012-09-13

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal