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MX2012007834A - Derivados de acido carboxilico que comprenden un anillo de oxazolopirimidina 2,5-sustituido. - Google Patents

Derivados de acido carboxilico que comprenden un anillo de oxazolopirimidina 2,5-sustituido.

Info

Publication number
MX2012007834A
MX2012007834A MX2012007834A MX2012007834A MX2012007834A MX 2012007834 A MX2012007834 A MX 2012007834A MX 2012007834 A MX2012007834 A MX 2012007834A MX 2012007834 A MX2012007834 A MX 2012007834A MX 2012007834 A MX2012007834 A MX 2012007834A
Authority
MX
Mexico
Prior art keywords
carboxylic acid
acid derivatives
oxazolopyrimidine ring
substituted oxazolopyrimidine
substituted
Prior art date
Application number
MX2012007834A
Other languages
English (en)
Inventor
Matthias Schaefer
Dieter Kadereit
Stephanie Hachtel
Axel Dietrich
Thomas Huebschle
Katrin Hiss
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MX2012007834A publication Critical patent/MX2012007834A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a compuestos de oxazolopirimidina de la fórmula I, (ver fórmula (I)) en la que A, R1, R2, R3 y X se definen como se ha indicado en las reivindicaciones. Los compuestos de la fórmula I son adecuados, p. ej., para la curación de heridas.
MX2012007834A 2010-01-14 2011-01-12 Derivados de acido carboxilico que comprenden un anillo de oxazolopirimidina 2,5-sustituido. MX2012007834A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10305042 2010-01-14
PCT/EP2011/050301 WO2011086079A1 (de) 2010-01-14 2011-01-12 Carbonsäurederivate mit einem 2,5-substituierten oxazolopyrimidinring

Publications (1)

Publication Number Publication Date
MX2012007834A true MX2012007834A (es) 2012-07-30

Family

ID=41800578

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012007834A MX2012007834A (es) 2010-01-14 2011-01-12 Derivados de acido carboxilico que comprenden un anillo de oxazolopirimidina 2,5-sustituido.

Country Status (31)

Country Link
US (1) US8846692B2 (es)
EP (1) EP2523962B1 (es)
JP (1) JP5841067B2 (es)
KR (1) KR101759128B1 (es)
CN (1) CN102791717B (es)
AR (1) AR079997A1 (es)
AU (1) AU2011206615B2 (es)
BR (1) BR112012017437B1 (es)
CA (1) CA2784560C (es)
CL (1) CL2012001972A1 (es)
CO (1) CO6612239A2 (es)
CY (1) CY1115055T1 (es)
DK (1) DK2523962T3 (es)
ES (1) ES2441954T3 (es)
HR (1) HRP20140179T1 (es)
IL (1) IL220720A (es)
MA (1) MA33917B1 (es)
MX (1) MX2012007834A (es)
MY (1) MY156550A (es)
NZ (1) NZ601113A (es)
PH (1) PH12012501265A1 (es)
PL (1) PL2523962T3 (es)
PT (1) PT2523962E (es)
RS (1) RS53254B (es)
RU (1) RU2564018C2 (es)
SG (1) SG182484A1 (es)
SI (1) SI2523962T1 (es)
TW (1) TWI510242B (es)
UY (1) UY33179A (es)
WO (1) WO2011086079A1 (es)
ZA (1) ZA201204174B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY33177A (es) 2010-01-13 2011-08-31 Sanofi Aventis Derivados de ácido carboxílico que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido
AR079980A1 (es) 2010-01-13 2012-03-07 Sanofi Aventis Derivados de oxazolopirimidina sustituida en 2,5,7
AU2011206617B2 (en) * 2010-01-14 2015-07-16 Sanofi 2,5-substituted oxazolopyrimidine derivatives
EP2523960B1 (de) * 2010-01-14 2013-10-16 Sanofi Heterocyclische carbonsäurederivate mit einem 2,5-substituierten oxazolopyrimidinring
US9321787B2 (en) * 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring
EP2862574A1 (en) * 2013-10-15 2015-04-22 Sanofi {4-[5-(3-chloro-phenoxy)-oxazolo[5,4 d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-acetic acid for use in the prevention or treatment of acute kidney injury

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679682A (en) * 1970-04-23 1972-07-25 Fmc Corp CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES
JPH01242587A (ja) * 1988-03-25 1989-09-27 Sankyo Co Ltd 縮環オキサゾロチエノピリミジン誘導体
MXPA05010802A (es) 2003-04-25 2005-12-14 Univ Cardiff Compuestos heterociclicos para el uso en el tratamiento de infecciones virales.
EP1622866B1 (en) * 2003-04-30 2012-07-25 Novartis AG Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators
EP2644195A1 (en) * 2003-05-19 2013-10-02 Irm Llc Immunosuppressant Compounds and Compositions
PL1638551T3 (pl) * 2003-05-19 2012-05-31 Irm Llc Związki i kompozycje immunosupresyjne
JP2009506046A (ja) * 2005-08-23 2009-02-12 アイアールエム・リミテッド・ライアビリティ・カンパニー 免疫抑制剤化合物および組成物
JP5191497B2 (ja) * 2007-03-21 2013-05-08 エピックス ファーマシューティカルズ，インコーポレイテッド Ｓ１ｐ受容体調節化合物およびその使用
TW201000099A (en) * 2008-06-20 2010-01-01 Amgen Inc S1P1 receptor agonists and use thereof
JP5449346B2 (ja) 2008-07-15 2014-03-19 サノフイ Ｅｄｇ−１受容体アゴニストとしてのオキサゾロピリミジン類
UY33177A (es) * 2010-01-13 2011-08-31 Sanofi Aventis Derivados de ácido carboxílico que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido
AR079980A1 (es) * 2010-01-13 2012-03-07 Sanofi Aventis Derivados de oxazolopirimidina sustituida en 2,5,7
AR079982A1 (es) * 2010-01-13 2012-03-07 Sanofi Aventis Derivados de acido carboxilico heterociclicos que comprenden un anillo de oxazolopirimidina 2,5,7- sustituido., composiciones farmaceuticas y procesos para prepararlos.
AU2011206617B2 (en) * 2010-01-14 2015-07-16 Sanofi 2,5-substituted oxazolopyrimidine derivatives
EP2523960B1 (de) * 2010-01-14 2013-10-16 Sanofi Heterocyclische carbonsäurederivate mit einem 2,5-substituierten oxazolopyrimidinring

Also Published As

Publication number Publication date
ES2441954T3 (es) 2014-02-07
RS53254B (sr) 2014-08-29
ZA201204174B (en) 2013-02-27
US20130079358A1 (en) 2013-03-28
CY1115055T1 (el) 2016-12-14
SI2523962T1 (sl) 2014-02-28
CN102791717A (zh) 2012-11-21
NZ601113A (en) 2013-07-26
CL2012001972A1 (es) 2012-10-19
CN102791717B (zh) 2016-03-30
WO2011086079A1 (de) 2011-07-21
JP5841067B2 (ja) 2016-01-06
HK1178885A1 (en) 2013-09-19
RU2564018C2 (ru) 2015-09-27
AU2011206615B2 (en) 2015-03-19
EP2523962A1 (de) 2012-11-21
PH12012501265A1 (en) 2016-07-27
SG182484A1 (en) 2012-08-30
KR101759128B1 (ko) 2017-07-18
UY33179A (es) 2011-08-31
JP2013517241A (ja) 2013-05-16
CA2784560C (en) 2017-12-05
AU2011206615A1 (en) 2012-08-02
BR112012017437B1 (pt) 2022-03-03
MY156550A (en) 2016-02-26
CA2784560A1 (en) 2011-07-21
BR112012017437A2 (pt) 2021-03-02
RU2012134630A (ru) 2014-02-20
IL220720A0 (en) 2012-08-30
CO6612239A2 (es) 2013-02-01
HRP20140179T1 (hr) 2014-03-28
PT2523962E (pt) 2014-02-06
TWI510242B (zh) 2015-12-01
MA33917B1 (fr) 2013-01-02
EP2523962B1 (de) 2013-11-27
KR20120101732A (ko) 2012-09-14
AR079997A1 (es) 2012-03-07
PL2523962T3 (pl) 2014-05-30
DK2523962T3 (en) 2014-03-10
IL220720A (en) 2015-02-26
TW201134475A (en) 2011-10-16
US8846692B2 (en) 2014-09-30

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