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MX2012006851A - Granulos para preparaciones farmceuticas, metodos y aparatos para su produccion. - Google Patents

Granulos para preparaciones farmceuticas, metodos y aparatos para su produccion.

Info

Publication number
MX2012006851A
MX2012006851A MX2012006851A MX2012006851A MX2012006851A MX 2012006851 A MX2012006851 A MX 2012006851A MX 2012006851 A MX2012006851 A MX 2012006851A MX 2012006851 A MX2012006851 A MX 2012006851A MX 2012006851 A MX2012006851 A MX 2012006851A
Authority
MX
Mexico
Prior art keywords
granules
pharmaceutical preparations
methods
production
preparations
Prior art date
Application number
MX2012006851A
Other languages
English (en)
Inventor
Jorgen Wittendorff
Carsten Hoeg-Moller
Crilles Casper Larsen
Brigitte Nissen
Kenneth Manby Pedersen
Tue Hansen
Helle Poulsen
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42110308&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2012006851(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferring Bv filed Critical Ferring Bv
Publication of MX2012006851A publication Critical patent/MX2012006851A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/609—Amides, e.g. salicylamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/606—Salicylic acid; Derivatives thereof having amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se dan a conocer preparaciones farmacéuticas granulares mejoradas, junto con métodos y aparatos mejorados para la preparación de gránulos para el uso en estas preparaciones. Estos métodos son especialmente útiles para hacer gránulos para preparaciones farmacéuticas de dosis orales sólidas y son particularmente adecuados para la producción de gránulos que comprenden ácido 5-aminosalicílico (5-ASA) para el tratamiento de la enfermedad inflamatoria intestinal. Los gránulos exhiben una distribución de longitud con picos más agudos, y por lo tanto una distribución de relación de aspecto, y consecuentemente tienen un perfil de disolución mucho más agudo después del procesamiento adicional.
MX2012006851A 2009-12-18 2010-12-15 Granulos para preparaciones farmceuticas, metodos y aparatos para su produccion. MX2012006851A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09179877A EP2340812A1 (en) 2009-12-18 2009-12-18 Granules for pharmaceutical preparations, methods and apparatus for their production
PCT/EP2010/069733 WO2011073245A2 (en) 2009-12-18 2010-12-15 Granules for pharmaceutical preparations, methods and apparatus for their production

Publications (1)

Publication Number Publication Date
MX2012006851A true MX2012006851A (es) 2012-08-31

Family

ID=42110308

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2012006851A MX2012006851A (es) 2009-12-18 2010-12-15 Granulos para preparaciones farmceuticas, metodos y aparatos para su produccion.
MX2014011350A MX351365B (es) 2009-12-18 2010-12-15 Gránulos para preparaciones farmacéuticas, métodos y aparatos para su producción.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2014011350A MX351365B (es) 2009-12-18 2010-12-15 Gránulos para preparaciones farmacéuticas, métodos y aparatos para su producción.

Country Status (28)

Country Link
US (2) US8765185B2 (es)
EP (2) EP2340812A1 (es)
JP (1) JP5593396B2 (es)
KR (1) KR101882880B1 (es)
CN (2) CN102791257B (es)
AR (1) AR079536A1 (es)
AU (1) AU2010332884B2 (es)
BR (1) BR112012014935B1 (es)
CA (1) CA2784235C (es)
DK (1) DK2512453T4 (es)
ES (1) ES2612870T5 (es)
FI (1) FI2512453T4 (es)
HR (1) HRP20161639T4 (es)
HU (1) HUE031228T2 (es)
IL (1) IL220319A (es)
JO (1) JO3762B1 (es)
LT (1) LT2512453T (es)
MX (2) MX2012006851A (es)
NL (1) NL1038373C2 (es)
NZ (1) NZ600582A (es)
PL (1) PL2512453T5 (es)
PT (1) PT2512453T (es)
RS (1) RS55438B2 (es)
RU (1) RU2584349C2 (es)
SI (1) SI2512453T2 (es)
TW (1) TWI511723B (es)
WO (1) WO2011073245A2 (es)
ZA (1) ZA201204441B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2520197A1 (en) * 2003-04-23 2004-11-04 Ferring B.V. Sachet for a pharmaceutical composition
EP4342465A3 (en) 2008-10-02 2024-06-12 Salix Pharmaceuticals, Inc. Methods of treating hepatic encephalopathy
EP2340812A1 (en) 2009-12-18 2011-07-06 Ferring International Center S.A. Granules for pharmaceutical preparations, methods and apparatus for their production
US20140141075A1 (en) 2012-11-21 2014-05-22 Warner Chilcott Company, Llc 5-aminosalicylic acid capsule formulation
DE202017102645U1 (de) * 2017-05-03 2018-08-06 Romaco Kilian Gmbh Ablaufvorrichtung für Presslinge einer Rundläufer-Tablettenpresse sowie Rundläufer-Tablettenpresse mit Ablaufvorrichtung
RU2667637C1 (ru) * 2017-06-26 2018-09-21 Гермес Арцнаймиттель ГмбХ Фармацевтическая композиция для перорального применения, содержащая n-ацетилцистеин с маскированным вкусом
EP3459529A1 (en) 2017-09-20 2019-03-27 Tillotts Pharma Ag Preparation of sustained release solid dosage forms comprising antibodies by spray drying
EP3459527B1 (en) 2017-09-20 2022-11-23 Tillotts Pharma Ag Method for preparing a solid dosage form comprising antibodies by wet granulation, extrusion and spheronization
ES2938609T3 (es) 2017-09-20 2023-04-13 Tillotts Pharma Ag Preparación de formas farmacéuticas sólidas que comprenden anticuerpos mediante estratificación de solución/suspensión
KR102161235B1 (ko) * 2020-07-22 2020-09-29 주식회사 피티케이 이송 일체형 과립 제조 장치 및 방법
CN116033892A (zh) * 2020-08-18 2023-04-28 悠哈味觉糖有限公司 口中速崩性固体食品及其制造方法
CN114472139A (zh) * 2022-01-04 2022-05-13 安徽宏信药业发展有限公司 一种中药药丸干燥筛选装置
CN115445902B (zh) * 2022-09-21 2023-06-06 重庆科技学院 一种条形颗粒物三维尺寸分选方法及装置
WO2024200722A1 (en) 2023-03-28 2024-10-03 Tillotts Pharma Ag Solid oral dosage form comprising antibodies for sustained release in the lower gastrointestinal tract
CN116942532B (zh) * 2023-09-20 2023-12-12 北京爱力佳医药科技有限公司 一种粉状药物制备装置

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US4720473A (en) * 1986-03-10 1988-01-19 Cri International, Inc. Production of improved catalyst-type particles using length and density grading
DE3786544T2 (de) * 1986-03-10 1994-02-03 Cri Int Inc Verfahren zur Sortierung und Isolierung von Katalysator-Formteilchen nach ihrer Länge.
JPH0827133B2 (ja) 1993-07-13 1996-03-21 不二パウダル株式会社 湿潤粉粒体の処理装置
CZ289290B6 (cs) 1995-12-21 2001-12-12 Farmaceutisk Laboratorium Ferring A/S Orální přípravek s modifikovaným uvolňováním
US6004581A (en) * 1995-12-21 1999-12-21 Farmaceutisk Laboratorium Ferring A/S Modified release oral pharmaceutical composition and method for the treatment of bowel diseases
AUPO637197A0 (en) 1997-04-23 1997-05-15 F.H. Faulding & Co. Limited Taste-masked pharmaceutical compositions
DE19724181A1 (de) * 1997-06-09 1998-12-10 Bayer Ag Multiple-unit-retard-Zubereitungen und Verfahren zu ihrer Herstellung
JP2000128774A (ja) 1998-10-26 2000-05-09 Tanabe Seiyaku Co Ltd 薬物を含有する球形微粒子の製法
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BR9916972B1 (pt) * 1999-01-29 2010-05-18 composições farmacêuticas de liberação retardada melhorada, bem como seu processo de produção.
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Also Published As

Publication number Publication date
WO2011073245A3 (en) 2011-08-11
MX351365B (es) 2017-10-12
HRP20161639T4 (hr) 2025-06-20
IL220319A0 (en) 2012-08-30
EP2512453B1 (en) 2016-11-09
TWI511723B (zh) 2015-12-11
CN105769772A (zh) 2016-07-20
US8765185B2 (en) 2014-07-01
ZA201204441B (en) 2013-02-27
US20130022681A1 (en) 2013-01-24
DK2512453T4 (da) 2025-06-02
JP2013514312A (ja) 2013-04-25
ES2612870T3 (es) 2017-05-19
HUE031228T2 (en) 2017-07-28
EP2340812A1 (en) 2011-07-06
EP2512453A2 (en) 2012-10-24
CA2784235A1 (en) 2011-06-23
KR20120102775A (ko) 2012-09-18
WO2011073245A2 (en) 2011-06-23
DK2512453T3 (en) 2017-01-09
IL220319A (en) 2016-03-31
NL1038373C2 (en) 2011-06-21
BR112012014935B1 (pt) 2021-12-21
CN102791257A (zh) 2012-11-21
RU2584349C2 (ru) 2016-05-20
US20140328934A1 (en) 2014-11-06
ES2612870T5 (en) 2025-05-09
US9114083B2 (en) 2015-08-25
RS55438B2 (sr) 2025-06-30
AU2010332884A1 (en) 2012-07-05
LT2512453T (lt) 2016-12-27
AR079536A1 (es) 2012-02-01
SI2512453T2 (sl) 2025-06-30
JO3762B1 (ar) 2021-01-31
PT2512453T (pt) 2016-12-16
NZ600582A (en) 2014-09-26
TW201125556A (en) 2011-08-01
KR101882880B1 (ko) 2018-07-27
JP5593396B2 (ja) 2014-09-24
RS55438B1 (sr) 2017-04-28
PL2512453T3 (pl) 2017-03-31
CN102791257B (zh) 2017-03-01
FI2512453T4 (fi) 2025-05-23
FI2512453T9 (fi) 2025-06-13
CA2784235C (en) 2019-01-15
SI2512453T1 (sl) 2017-02-28
EP2512453B2 (en) 2025-03-12
BR112012014935A2 (pt) 2016-03-08
RU2012124834A (ru) 2014-01-27
HRP20161639T1 (hr) 2017-02-10
AU2010332884B2 (en) 2015-12-10
PL2512453T5 (pl) 2025-07-07

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