MX2012006720A - Composicion farmceutica para el tratamiento de sindrome del ojo seco. - Google Patents
Composicion farmceutica para el tratamiento de sindrome del ojo seco.Info
- Publication number
- MX2012006720A MX2012006720A MX2012006720A MX2012006720A MX2012006720A MX 2012006720 A MX2012006720 A MX 2012006720A MX 2012006720 A MX2012006720 A MX 2012006720A MX 2012006720 A MX2012006720 A MX 2012006720A MX 2012006720 A MX2012006720 A MX 2012006720A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- pharmaceutical composition
- dry eye
- eye syndrome
- compositions
- Prior art date
Links
- 208000003556 Dry Eye Syndromes Diseases 0.000 title abstract 2
- 206010013774 Dry eye Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 208000009319 Keratoconjunctivitis Sicca Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001335 aliphatic alkanes Chemical class 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La invención proporciona nuevas composiciones farmacéuticas para el tratamiento de la queratoconjuntivitis seca que comprenden vehículos líquidos que incluyen uno o más alcanos semifluorados. Las composiciones incorporan un ingrediente activo escogido entre el grupo de inmunosupresores de macrolida. Se pueden administrar por vía tópica al ojo. La invención además proporciona estuches que comprenden dichas composiciones.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09015423A EP2335735A1 (en) | 2009-12-14 | 2009-12-14 | Pharmaceutical composition for treatment of dry eye syndrome |
| PCT/EP2010/069495 WO2011073134A1 (en) | 2009-12-14 | 2010-12-13 | Pharmaceutical composition for treatment of dry eye syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012006720A true MX2012006720A (es) | 2012-07-30 |
Family
ID=41731659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012006720A MX2012006720A (es) | 2009-12-14 | 2010-12-13 | Composicion farmceutica para el tratamiento de sindrome del ojo seco. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8614178B2 (es) |
| EP (2) | EP2335735A1 (es) |
| JP (5) | JP5663595B2 (es) |
| KR (2) | KR101722039B1 (es) |
| CN (1) | CN102652022B (es) |
| AU (1) | AU2010333039B2 (es) |
| BR (3) | BR122020020872B1 (es) |
| CA (2) | CA2941956C (es) |
| DK (1) | DK2512515T3 (es) |
| ES (1) | ES2449308T3 (es) |
| IN (1) | IN2012DN03128A (es) |
| MX (1) | MX2012006720A (es) |
| PL (1) | PL2512515T3 (es) |
| PT (1) | PT2512515E (es) |
| WO (1) | WO2011073134A1 (es) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4108216A1 (en) | 2009-06-03 | 2022-12-28 | Forsight Vision5, Inc. | Anterior segment drug delivery |
| US10045996B2 (en) | 2010-03-17 | 2018-08-14 | Novaliq Gmbh | Pharmaceutical composition for treatment of increased intraocular pressure |
| EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
| EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
| CN103561724B (zh) | 2011-05-25 | 2016-06-29 | 诺瓦利克有限责任公司 | 给药给甲的药物组合物 |
| ES2623233T3 (es) | 2011-05-25 | 2017-07-10 | Novaliq Gmbh | Composición farmacéutica tópica a base de alcanos semifluorados |
| JP6084987B2 (ja) | 2012-01-23 | 2017-02-22 | ノバリック ゲーエムベーハー | セミフッ素化アルカンに基づく安定化タンパク質組成物 |
| TR201812013T4 (tr) | 2012-09-12 | 2018-09-21 | Novaliq Gmbh | Göz yikama bi̇leşi̇mleri̇. |
| EP3100722B1 (en) * | 2012-09-12 | 2024-03-20 | Novaliq GmbH | Semifluorinated alkanes for use in solubilizing meibum |
| US9770508B2 (en) * | 2012-09-12 | 2017-09-26 | Novaliq Gmbh | Semifluorinated alkane compositions |
| EP2730291A1 (en) * | 2012-11-09 | 2014-05-14 | Fluoron Gmbh | Internal Tamponade Composition |
| AU2014209141B2 (en) | 2013-01-24 | 2018-05-10 | Palvella Therapeutics, Inc. | Compositions for transdermal delivery of mTOR inhibitors |
| JP6304475B2 (ja) * | 2013-01-31 | 2018-04-04 | ロート製薬株式会社 | 点眼剤 |
| JP6265793B2 (ja) * | 2013-03-13 | 2018-01-24 | 参天製薬株式会社 | マイボーム機能不全の治療剤 |
| CN105555311B (zh) | 2013-07-23 | 2021-10-08 | 诺瓦利克有限责任公司 | 稳定的抗体组合物 |
| US20160243291A1 (en) * | 2013-10-15 | 2016-08-25 | Forsight Vision5, Inc. | Formulations and Methods for Increasing or Reducing Mucus |
| US20200237859A1 (en) | 2019-01-25 | 2020-07-30 | Newport Research, Inc. | Aqueous suspensions of cyclosporin |
| US11324800B2 (en) | 2015-01-15 | 2022-05-10 | Wellspring Ophthalmics, Inc. | Aqueous suspensions of cyclosporin |
| WO2016168141A1 (en) | 2015-04-13 | 2016-10-20 | Forsight Vision5, Inc. | Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent |
| US11013403B2 (en) * | 2015-09-29 | 2021-05-25 | The Regents Of The University Of California | Methods of diagnosing diseases of mucosal surfaces |
| ES2953837T3 (es) * | 2015-09-30 | 2023-11-16 | Novaliq Gmbh | 2-perfluorobutil pentano para administración oftálmica |
| WO2017055454A1 (en) | 2015-09-30 | 2017-04-06 | Novaliq Gmbh | Semifluorinated compounds and their compositions |
| PT3442480T (pt) | 2016-06-23 | 2019-12-23 | Novaliq Gmbh | Método de administração tópica |
| US11684589B2 (en) | 2016-09-22 | 2023-06-27 | Novaliq Gmbh | Pharmaceutical compositions for use in the therapy of blepharitis |
| EP3515467B1 (en) * | 2016-09-23 | 2023-11-29 | Novaliq GmbH | Ophthalmic compositions comprising ciclosporin |
| MX2019003544A (es) * | 2016-09-28 | 2019-09-19 | Novaliq Gmbh | Composiciones que comprenden un ligando de union al receptor cannabinoide. |
| AU2017380769B2 (en) * | 2016-12-22 | 2023-12-21 | Novaliq Gmbh | Compositions comprising tacrolimus for the treatment of intraocular inflammatory eye diseases |
| PT3399962T (pt) * | 2016-12-23 | 2020-09-03 | Novaliq Gmbh | Composição oftálmica para o tratamento da doença do olho seco |
| EP3565520A4 (en) | 2017-01-06 | 2020-08-19 | Palvella Therapeutics, Inc. | ANHYDROUS COMPOSITIONS OF MTOR INHIBITORS AND METHODS OF USE |
| WO2018193093A1 (en) * | 2017-04-21 | 2018-10-25 | Novaliq Gmbh | Iodine compositions |
| US10717691B2 (en) | 2017-05-05 | 2020-07-21 | Novaliq Gmbh | Process for the production of semifluorinated alkanes |
| CN110650734B (zh) * | 2017-05-12 | 2024-11-15 | 诺瓦利克有限责任公司 | 治疗与隐形眼镜有关病症的包含半氟化烷烃的药物组合物 |
| KR20200059272A (ko) | 2017-09-27 | 2020-05-28 | 노바리크 게엠베하 | 안구 질환의 치료에서의 사용을 위한 라타노프로스트를 포함하는 안과적 조성물 |
| CN119909046A (zh) | 2017-10-04 | 2025-05-02 | 诺瓦利克有限责任公司 | 包含f6h8的眼用组合物 |
| AU2019228119A1 (en) | 2018-03-02 | 2020-09-10 | Novaliq Gmbh | Pharmaceutical compositions comprising nebivolol |
| WO2019206956A1 (en) | 2018-04-27 | 2019-10-31 | Novaliq Gmbh | Ophthalmic compositions comprising tafluprost for the treatment of glaucoma |
| WO2020010073A1 (en) | 2018-07-02 | 2020-01-09 | Palvella Therapeutics, Inc. | ANHYDROUS COMPOSITIONS OF mTOR INHIBITORS AND METHODS OF USE |
| KR20210080388A (ko) | 2018-09-22 | 2021-06-30 | 노바리크 게엠베하 | 안구 표면 손상 및 건조 증상 치료를 위한 안약 조성물 |
| KR102808092B1 (ko) | 2018-09-27 | 2025-05-22 | 더마리크 테라퓨틱스, 인크. | 지질 장벽 수복 |
| CA3112031A1 (en) | 2018-10-12 | 2020-04-16 | Novaliq Gmbh | Ophthalmic composition for treatment of dry eye disease |
| CN113518619A (zh) * | 2019-01-21 | 2021-10-19 | 诺瓦利克有限责任公司 | 用于治疗眼部新生血管形成的药物组合物 |
| WO2020165132A1 (en) | 2019-02-13 | 2020-08-20 | Novaliq Gmbh | Compositions and methods for the treatment of ocular neovascularization |
| CA3141386A1 (en) | 2019-05-24 | 2020-12-03 | Novaliq Gmbh | Ophthalmic composition for the treatment of ocular allergy |
| WO2021044045A1 (en) | 2019-09-06 | 2021-03-11 | Novaliq Gmbh | Ophthalmic composition for the treatment of uveitis |
| WO2021048803A1 (en) | 2019-09-13 | 2021-03-18 | Minas Coroneo | Eye drop dispenser |
| WO2021191273A1 (en) | 2020-03-24 | 2021-09-30 | Hovione Scientia Limited | Compositions for use in treating meibomian gland dysfunction |
| US11191751B1 (en) * | 2020-10-08 | 2021-12-07 | Ads Therapeutics Llc | Topical ophthalmological atropine free base compositions |
| IL322635A (en) * | 2023-02-13 | 2025-10-01 | Novaliq Gmbh | Ophthalmic preparation for eye surgery in patients with ocular surface disease |
| AU2023270196B2 (en) * | 2023-11-20 | 2025-06-26 | Dyer, Gordon Wayne DR | Method of Arthropod Egress |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4839342A (en) | 1987-09-03 | 1989-06-13 | University Of Georgia Research Foundation, Inc. | Method of increasing tear production by topical administration of cyclosporin |
| KR920003601B1 (ko) | 1987-09-03 | 1992-05-04 | 유니버시티 어브 죠지아 리서취 화운데이션 인코포레이티드 | 점안 싸이클로스포린(cyclosporin)의 조성물 |
| US5874481A (en) * | 1995-06-07 | 1999-02-23 | Alliance Pharmaceutical Corp. | Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents |
| DE19536504C2 (de) * | 1995-09-29 | 1999-09-23 | H Meinert | Verwendung fluorierter Alkane |
| DE19861012A1 (de) * | 1998-03-18 | 1999-09-30 | Pharm Pur Gmbh | Behandlungsmittel für die Ophthalmologie |
| CZ20013769A3 (cs) * | 1999-04-30 | 2002-03-13 | Sucampo Ag | Činidlo pro léčbu suchého oka |
| DE19938668B4 (de) * | 1999-08-14 | 2006-01-26 | Bausch & Lomb Inc. | Tränenersatzmittel |
| US20030018044A1 (en) * | 2000-02-18 | 2003-01-23 | Peyman Gholam A. | Treatment of ocular disease |
| EP1740189B1 (en) * | 2004-04-19 | 2012-06-13 | Centre National De La Recherche Scientifique -Cnrs- | Lung surfactant supplements |
| US20050288197A1 (en) * | 2004-06-08 | 2005-12-29 | Ocularis Pharma, Inc. | Silicone polymer topical eye compositions and methods of use |
| DE102007055046A1 (de) * | 2007-11-19 | 2009-05-28 | Fluoron Gmbh | Infusionslösung |
| DK2110126T3 (da) | 2008-04-18 | 2012-02-27 | Novaliq Gmbh | Inhalations- og instillationsanvendelse af semifluorerede alkaner som aktiv bestanddel-bærere inden for det intrapulmonale område |
-
2009
- 2009-12-14 EP EP09015423A patent/EP2335735A1/en not_active Withdrawn
-
2010
- 2010-12-13 BR BR122020020872-4A patent/BR122020020872B1/pt active IP Right Grant
- 2010-12-13 CN CN201080055507.7A patent/CN102652022B/zh active Active
- 2010-12-13 CA CA2941956A patent/CA2941956C/en active Active
- 2010-12-13 PL PL10790775T patent/PL2512515T3/pl unknown
- 2010-12-13 IN IN3128DEN2012 patent/IN2012DN03128A/en unknown
- 2010-12-13 PT PT107907750T patent/PT2512515E/pt unknown
- 2010-12-13 JP JP2012542577A patent/JP5663595B2/ja active Active
- 2010-12-13 CA CA2776860A patent/CA2776860C/en active Active
- 2010-12-13 DK DK10790775.0T patent/DK2512515T3/en active
- 2010-12-13 AU AU2010333039A patent/AU2010333039B2/en active Active
- 2010-12-13 US US13/513,886 patent/US8614178B2/en active Active
- 2010-12-13 KR KR1020167023214A patent/KR101722039B1/ko active Active
- 2010-12-13 MX MX2012006720A patent/MX2012006720A/es active IP Right Grant
- 2010-12-13 BR BR122017018955-7A patent/BR122017018955B1/pt active IP Right Grant
- 2010-12-13 ES ES10790775.0T patent/ES2449308T3/es active Active
- 2010-12-13 BR BR112012014190A patent/BR112012014190B8/pt active IP Right Grant
- 2010-12-13 WO PCT/EP2010/069495 patent/WO2011073134A1/en not_active Ceased
- 2010-12-13 EP EP10790775.0A patent/EP2512515B1/en active Active
- 2010-12-13 KR KR1020127018066A patent/KR101652714B1/ko active Active
-
2014
- 2014-10-01 JP JP2014203406A patent/JP6096731B2/ja active Active
-
2016
- 2016-12-22 JP JP2016248533A patent/JP6397472B2/ja active Active
-
2018
- 2018-08-31 JP JP2018163569A patent/JP2019006803A/ja active Pending
- 2018-12-28 JP JP2018248700A patent/JP6731039B2/ja active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |