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MX2012004550A - Formulacion de absorcion transdermica que contiene donepezil. - Google Patents

Formulacion de absorcion transdermica que contiene donepezil.

Info

Publication number
MX2012004550A
MX2012004550A MX2012004550A MX2012004550A MX2012004550A MX 2012004550 A MX2012004550 A MX 2012004550A MX 2012004550 A MX2012004550 A MX 2012004550A MX 2012004550 A MX2012004550 A MX 2012004550A MX 2012004550 A MX2012004550 A MX 2012004550A
Authority
MX
Mexico
Prior art keywords
donepezil
containing preparation
transdermally absorbable
absorption
base material
Prior art date
Application number
MX2012004550A
Other languages
English (en)
Inventor
Masahiro Yamaji
Satoshi Kawakami
Original Assignee
Teikoku Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Seiyaku Kk filed Critical Teikoku Seiyaku Kk
Publication of MX2012004550A publication Critical patent/MX2012004550A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se proporciona una formulación de absorción transdérmica que contiene donepezil que puede administrar de manera sostenida donepezil durante un período prolongado de tiempo, y puede proporcionar tanto un incremento rápido en el nivel sanguíneo de donepezil como propiedades de liberación sostenida de donepezil. La formulación de absorción transdérmica que contiene donepezil es una formulación de absorción transdérmica producida al disolver donepezil, que es el ingrediente activo, en una base de parche adhesivo que contiene un polímero hidrófobo y un promotor de absorción. El promotor de absorción es una clase o dos o más clases seleccionadas de alcohol laurílico, citrato de trietilo, miristato de isopropilo, lactato de cetilo, alcohol oleilico, monooleato de sorbitan, monoestearato de polietilenglicol, lauromacrogol, N-metil-2-pirrolidona, y triacetina.
MX2012004550A 2009-10-21 2010-10-18 Formulacion de absorcion transdermica que contiene donepezil. MX2012004550A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009242656 2009-10-21
PCT/JP2010/068260 WO2011049038A1 (ja) 2009-10-21 2010-10-18 ドネペジル含有経皮吸収型製剤

Publications (1)

Publication Number Publication Date
MX2012004550A true MX2012004550A (es) 2012-05-29

Family

ID=43900264

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012004550A MX2012004550A (es) 2009-10-21 2010-10-18 Formulacion de absorcion transdermica que contiene donepezil.

Country Status (13)

Country Link
US (1) US8840922B2 (es)
EP (1) EP2491931B1 (es)
JP (1) JP5913981B2 (es)
KR (1) KR101734602B1 (es)
CN (1) CN102573843B (es)
AU (1) AU2010309030B2 (es)
BR (1) BR112012011334A2 (es)
CA (1) CA2778103C (es)
ES (1) ES2652491T3 (es)
MX (1) MX2012004550A (es)
RU (1) RU2545696C2 (es)
TW (1) TWI481425B (es)
WO (1) WO2011049038A1 (es)

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US20120282303A1 (en) * 2009-12-16 2012-11-08 Takeshi Ito Percutaneous absorption preparation comprising anti-dementia drug
US20130202677A1 (en) * 2010-09-30 2013-08-08 Sekisui Medical Co. Ltd Patch
TWI433904B (zh) * 2011-01-12 2014-04-11 Taiwan Biotech Co Ltd 多奈哌齊經皮貼片
WO2013035850A1 (ja) * 2011-09-08 2013-03-14 株式会社 ケイ・エム トランスダーム 経皮吸収製剤
WO2013187451A1 (ja) * 2012-06-12 2013-12-19 株式会社 ケイ・エム トランスダーム 貼付剤
CN102895217A (zh) * 2012-11-13 2013-01-30 沈阳药科大学 长效多奈哌齐经皮吸收贴剂
KR101811797B1 (ko) * 2013-04-03 2017-12-22 동국제약 주식회사 도네페질을 포함하는 비경구투여용 약제학적 조성물
KR101485822B1 (ko) 2014-01-22 2015-01-23 주식회사 대웅제약 도네페질 또는 그의 염을 함유하는 경피흡수제제
KR20160120778A (ko) * 2014-02-20 2016-10-18 날 파마슈티칼 그룹 리미티드 도네페질을 함유하는 경피흡수제제
WO2017014306A1 (ja) * 2015-07-22 2017-01-26 積水化学工業株式会社 製剤
US10835499B2 (en) 2015-12-30 2020-11-17 Corium, Inc. Systems and methods for long term transdermal administration
US11541018B2 (en) 2016-06-23 2023-01-03 Corium, Llc Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent
AU2017302305A1 (en) 2016-07-27 2019-02-14 Corium, LLC. Transdermal delivery systems with pharmacokinetics bioequivalent to oral delivery
CA3032103A1 (en) 2016-07-27 2018-02-01 Corium International, Inc. Memantine transdermal delivery systems
KR20230109782A (ko) 2016-07-27 2023-07-20 코리움, 엘엘씨 아민 약물의 나트륨 바이카보네이트 제자리 전환 구동된경피성 전달
KR102033686B1 (ko) 2017-05-19 2019-10-18 보령제약 주식회사 도네페질을 함유하는 마이크로니들 경피 패치
JP2019034905A (ja) * 2017-08-17 2019-03-07 コスメディ製薬株式会社 デヒドロ酢酸含有経皮吸収製剤
WO2019088010A1 (ja) * 2017-10-30 2019-05-09 帝國製薬株式会社 経皮投与製剤
US11173132B2 (en) 2017-12-20 2021-11-16 Corium, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point
KR102024996B1 (ko) * 2017-12-27 2019-09-25 동아에스티 주식회사 도네페질을 함유하는 치매 치료용 경피흡수제제
KR102115102B1 (ko) 2018-12-21 2020-05-26 동아에스티 주식회사 안정화된 도네페질 함유 경피 흡수제제
KR102372630B1 (ko) 2019-05-15 2022-03-14 주식회사 대웅제약 고함량의 도네페질 또는 그의 염을 포함하는 경피흡수제제
CN112823793A (zh) * 2019-11-20 2021-05-21 成都康弘药业集团股份有限公司 一种含有多奈哌齐的透皮贴剂及其制备方法
KR20210133816A (ko) 2020-04-29 2021-11-08 신신제약 주식회사 도네페질을 함유하는 경피흡수제제
KR102227100B1 (ko) * 2020-08-14 2021-03-12 주식회사 종근당 도네페질 에테르 팔미테이트 또는 이의 약제학적으로 허용가능한 염
JP2022122784A (ja) 2021-02-10 2022-08-23 コスメディ製薬株式会社 酸化防止剤含有経皮吸収製剤
CN114796164B (zh) * 2022-05-24 2022-12-23 河南羚锐制药股份有限公司 一种挥发类药物快速释放的贴膏剂基质制备方法
JPWO2024127805A1 (es) * 2022-12-16 2024-06-20

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US5601839A (en) 1995-04-26 1997-02-11 Theratech, Inc. Triacetin as a penetration enhancer for transdermal delivery of a basic drug
JP3987655B2 (ja) 1998-03-03 2007-10-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗痴呆薬を含有した経皮適用製剤又は坐剤
WO2002045701A2 (en) * 2000-12-05 2002-06-13 Noven Pharmaceuticals, Inc. Crystallization inhibition of drugs in transdermal drug delivery systems
CN1571664A (zh) 2001-10-17 2005-01-26 久光制药株式会社 经皮吸收型制剂
JP5075334B2 (ja) * 2004-11-22 2012-11-21 久光製薬株式会社 薬物含有貼付剤
JP5097359B2 (ja) * 2006-05-09 2012-12-12 久光製薬株式会社 ドネペジル経皮吸収型製剤
JP5243254B2 (ja) * 2006-10-11 2013-07-24 久光製薬株式会社 結晶含有貼付剤
TW200838479A (en) * 2006-12-01 2008-10-01 Nitto Denko Corp Percutaneously absorbable preparation
JP2009022730A (ja) * 2007-06-18 2009-02-05 Kyoritsu Yakuhin Kogyo Kk 貼付剤
KR101454362B1 (ko) * 2008-03-24 2014-10-23 아이큐어 주식회사 도네페질을 유효성분으로 함유하는 치매 치료용경피흡수제제
KR20110020788A (ko) 2008-05-30 2011-03-03 에자이 알앤드디 매니지먼트 가부시키가이샤 경피 흡수 제제

Also Published As

Publication number Publication date
JPWO2011049038A1 (ja) 2013-03-14
EP2491931A1 (en) 2012-08-29
WO2011049038A1 (ja) 2011-04-28
AU2010309030B2 (en) 2013-10-31
EP2491931B1 (en) 2017-09-20
CA2778103C (en) 2017-11-07
CN102573843B (zh) 2014-09-24
BR112012011334A2 (pt) 2020-08-25
EP2491931A4 (en) 2013-06-12
US8840922B2 (en) 2014-09-23
AU2010309030A1 (en) 2012-05-10
TWI481425B (zh) 2015-04-21
CA2778103A1 (en) 2011-04-28
KR20120093293A (ko) 2012-08-22
RU2012120745A (ru) 2013-11-27
RU2545696C2 (ru) 2015-04-10
JP5913981B2 (ja) 2016-05-11
ES2652491T3 (es) 2018-02-02
US20120207816A1 (en) 2012-08-16
CN102573843A (zh) 2012-07-11
KR101734602B1 (ko) 2017-05-11
TW201119691A (en) 2011-06-16

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