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MX2011013902A - Tratamiento de esclerosis multiple con laquinimod. - Google Patents

Tratamiento de esclerosis multiple con laquinimod.

Info

Publication number
MX2011013902A
MX2011013902A MX2011013902A MX2011013902A MX2011013902A MX 2011013902 A MX2011013902 A MX 2011013902A MX 2011013902 A MX2011013902 A MX 2011013902A MX 2011013902 A MX2011013902 A MX 2011013902A MX 2011013902 A MX2011013902 A MX 2011013902A
Authority
MX
Mexico
Prior art keywords
laquinimod
reducing
multiple sclerosis
treatment
relapsing
Prior art date
Application number
MX2011013902A
Other languages
English (en)
Inventor
Nora Tarcic
Dan Bar-Zohar
Dina Kofler
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of MX2011013902A publication Critical patent/MX2011013902A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La invención objeto proporciona métodos para reducir la velocidad de recaída y/o reducir la acumulación de discapacidad física en un paciente humano con esclerosis múltiple recurrente-remitente, el método comprende administrar oralmente al paciente una dosis diaria de 0.6 mg de laquinimod. La invención objeto también proporciona formas de dosificación de unidad oral farmacéuticas de 0.6 mg de laquinimod para usar en reducir la velocidad de recaída y/o para usar en reducir la acumulación de discapacidad física en un paciente humano con esclerosis múltiple recurrente-remitente.
MX2011013902A 2009-06-19 2010-06-18 Tratamiento de esclerosis multiple con laquinimod. MX2011013902A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26907009P 2009-06-19 2009-06-19
PCT/US2010/001759 WO2010147665A1 (en) 2009-06-19 2010-06-18 Treatment of multiple sclerosis with laquinimod

Publications (1)

Publication Number Publication Date
MX2011013902A true MX2011013902A (es) 2012-02-23

Family

ID=43354572

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011013902A MX2011013902A (es) 2009-06-19 2010-06-18 Tratamiento de esclerosis multiple con laquinimod.

Country Status (25)

Country Link
US (7) US20100322900A1 (es)
EP (2) EP3028572A1 (es)
JP (4) JP2012530701A (es)
KR (2) KR20170109091A (es)
CN (2) CN107308162A (es)
AU (2) AU2010260455A1 (es)
BR (1) BR112012000568A2 (es)
CY (1) CY1116727T1 (es)
DK (1) DK2442651T3 (es)
EA (1) EA201270041A1 (es)
ES (1) ES2548999T3 (es)
HR (1) HRP20150988T1 (es)
HU (1) HUE026406T2 (es)
IL (2) IL216780A0 (es)
ME (1) ME02282B (es)
MX (1) MX2011013902A (es)
NZ (1) NZ597378A (es)
PL (1) PL2442651T3 (es)
PT (1) PT2442651E (es)
RS (1) RS54328B1 (es)
SG (2) SG176840A1 (es)
SI (1) SI2442651T1 (es)
SM (1) SMT201500262B (es)
WO (1) WO2010147665A1 (es)
ZA (1) ZA201200029B (es)

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TW201410244A (zh) 2012-08-13 2014-03-16 Teva Pharma 用於治療ｇａｂａ媒介之疾病之拉喹莫德（ｌａｑｕｉｎｉｍｏｄ）
JP2015533163A (ja) * 2012-10-12 2015-11-19 テバ ファーマシューティカル インダストリーズ リミティド 多発性硬化症における視床損傷を低減するためのラキニモド
KR20150091077A (ko) 2012-11-07 2015-08-07 테바 파마슈티컬 인더스트리즈 리미티드 라퀴니모드의 아민염
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Also Published As

Publication number Publication date
JP2016199555A (ja) 2016-12-01
HRP20150988T1 (hr) 2015-11-20
JP2015107981A (ja) 2015-06-11
US20170128435A1 (en) 2017-05-11
SMT201500262B (it) 2016-01-08
HK1169563A1 (en) 2013-02-01
JP2018021045A (ja) 2018-02-08
EP2442651B1 (en) 2015-07-29
KR20120037477A (ko) 2012-04-19
SG176840A1 (en) 2012-02-28
DK2442651T3 (en) 2015-09-21
US20150164880A1 (en) 2015-06-18
HUE026406T2 (en) 2016-06-28
PL2442651T3 (pl) 2015-12-31
IL252699A0 (en) 2017-07-31
US20160082001A1 (en) 2016-03-24
IL216780A0 (en) 2012-02-29
US20140105850A1 (en) 2014-04-17
BR112012000568A2 (pt) 2015-10-06
EP3028572A1 (en) 2016-06-08
WO2010147665A1 (en) 2010-12-23
RS54328B1 (sr) 2016-02-29
CY1116727T1 (el) 2017-03-15
EP2442651A1 (en) 2012-04-25
KR20170109091A (ko) 2017-09-27
JP2012530701A (ja) 2012-12-06
EP2442651A4 (en) 2012-10-31
NZ597378A (en) 2014-08-29
ME02282B (me) 2016-02-20
PT2442651E (pt) 2015-10-22
EA201270041A1 (ru) 2012-06-29
US20130272996A1 (en) 2013-10-17
AU2010260455A1 (en) 2012-02-02
US20180042916A1 (en) 2018-02-15
ES2548999T3 (es) 2015-10-22
US20100322900A1 (en) 2010-12-23
CN102802415A (zh) 2012-11-28
AU2016216586A1 (en) 2016-09-01
SG10201403397TA (en) 2014-10-30
ZA201200029B (en) 2013-03-27
CN107308162A (zh) 2017-11-03
SI2442651T1 (sl) 2015-10-30

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