[go: up one dir, main page]

MX2011012668A - Metodos de administracion de compuestos agonistas de trombopoyetina. - Google Patents

Metodos de administracion de compuestos agonistas de trombopoyetina.

Info

Publication number
MX2011012668A
MX2011012668A MX2011012668A MX2011012668A MX2011012668A MX 2011012668 A MX2011012668 A MX 2011012668A MX 2011012668 A MX2011012668 A MX 2011012668A MX 2011012668 A MX2011012668 A MX 2011012668A MX 2011012668 A MX2011012668 A MX 2011012668A
Authority
MX
Mexico
Prior art keywords
methods
administration
subject
agonist compounds
provide methods
Prior art date
Application number
MX2011012668A
Other languages
English (en)
Inventor
Julian Jenkins
Connie L Erickson-Miller
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43223061&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011012668(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of MX2011012668A publication Critical patent/MX2011012668A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/41521,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Las modalidades proveen métodos de administración de una dosis alta o una dosis de carga de un modulador de TPO a un sujeto; las modalidades también proveen métodos de tratamiento de la trombocitopenia y/o neutropenia en un sujeto; adicionalmente, las modalidades proveen métodos para aumentar la producción de plaquetas y/o aumentar el número de citoblastos de la sangre periférica en un sujeto.
MX2011012668A 2009-05-29 2010-05-27 Metodos de administracion de compuestos agonistas de trombopoyetina. MX2011012668A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18214809P 2009-05-29 2009-05-29
PCT/US2010/036294 WO2010138656A1 (en) 2009-05-29 2010-05-27 Methods of administration of thrombopoietin agonist compounds

Publications (1)

Publication Number Publication Date
MX2011012668A true MX2011012668A (es) 2011-12-16

Family

ID=43223061

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011012668A MX2011012668A (es) 2009-05-29 2010-05-27 Metodos de administracion de compuestos agonistas de trombopoyetina.

Country Status (20)

Country Link
US (1) US8609693B2 (es)
EP (2) EP3127427B1 (es)
JP (3) JP2012528184A (es)
KR (1) KR20120015355A (es)
CN (2) CN104173337A (es)
AU (1) AU2010254046C1 (es)
BR (1) BRPI1014548A2 (es)
CA (1) CA2763768A1 (es)
DK (1) DK3127427T3 (es)
EA (2) EA201690401A1 (es)
ES (2) ES2605593T3 (es)
HU (1) HUE049075T2 (es)
IL (1) IL216365A (es)
MX (1) MX2011012668A (es)
PL (2) PL3127427T3 (es)
PT (2) PT2434894T (es)
SG (1) SG176088A1 (es)
SI (1) SI3127427T1 (es)
WO (1) WO2010138656A1 (es)
ZA (1) ZA201108374B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010045310A1 (en) * 2008-10-16 2010-04-22 Glaxosmithkline Llc Method of treating thrombocytopenia
PL3127427T3 (pl) 2009-05-29 2020-06-15 Novartis Ag Sposoby podawania związków agonistów trombopoetyny

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE193350C (es)
US851444A (en) 1905-11-13 1907-04-23 Agfa Ag Amido-oxy-sulfonic acid of phenylnaphthimidazol and process of making same.
GB779880A (en) 1953-02-27 1957-07-24 Ciba Ltd Functional derivatives of azo-dyestuffs containing sulphonic acid groups and processfor making them
US2809963A (en) 1954-10-26 1957-10-15 Ciba Ltd Azo-dyestuffs
DE1046220B (de) 1956-04-21 1958-12-11 Bayer Ag Verfahren zur Herstellung von Monoazofarbstoffen und deren Metallkomplexverbindungen
GB826207A (en) 1956-07-23 1959-12-31 Bayer Ag ú´-ú´-dihydroxy-monoazo dyestuffs containing pyrrolidonyl residues and their metal complex compounds
US2950273A (en) 1956-11-20 1960-08-23 Agfa Ag Process for the production of symmetrical and unsymmetrical azo compounds
US3366619A (en) 1965-04-09 1968-01-30 Interchem Corp Disazo pyrazolone pigments
US4435417A (en) 1981-02-20 1984-03-06 Gruppo Lepetit S.P.A. Antiinflammatory 3H-naphtho[1,2-d]imidazoles
ES523609A0 (es) 1982-07-05 1985-03-01 Erba Farmitalia Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos.
FR2559483B1 (fr) 1984-02-10 1986-12-05 Sandoz Sa Composes heterocycliques contenant des groupes basiques et/ou cationiques, leur preparation et leur utilisation comme colorants
US4582831A (en) 1984-11-16 1986-04-15 Pfizer Inc. Anti-inflammatory polymorphic monoethanolamine salt of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide compound, composition, and method of use therefor
FI91869C (fi) 1987-03-18 1994-08-25 Tanabe Seiyaku Co Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi
US4880788A (en) 1987-10-30 1989-11-14 Baylor College Of Medicine Method for preventing and treating thrombosis
WO1993017681A1 (en) 1992-03-02 1993-09-16 Abbott Laboratories Angiotensin ii receptor antagonists
IL109570A0 (en) 1993-05-17 1994-08-26 Fujisawa Pharmaceutical Co Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof
EP0638617A1 (de) 1993-08-13 1995-02-15 Ciba-Geigy Ag Pigmentsalze
US5532202A (en) 1993-12-28 1996-07-02 Dai Nippon Printing Co., Ltd. Thermal transfer sheet
US5482546A (en) 1994-03-30 1996-01-09 Canon Kabushiki Kaisha Dye, ink containing the same, and ink-jet recording method and instrument using the ink
CN1229385C (zh) 1994-03-31 2005-11-30 安姆根有限公司 刺激巨核细胞生长和分化的组合物及方法
US5760038A (en) 1995-02-06 1998-06-02 Bristol-Myers Squibb Company Substituted biphenyl sulfonamide endothelin antagonists
US5746821A (en) 1995-02-13 1998-05-05 Engelhard Corporation Pigment compositions
KR100436680B1 (ko) 1995-06-07 2004-09-18 글락소 그룹 리미티드 트롬보포이에틴 수용체에 결합하는 펩티드 및 화합물
US5622818A (en) 1995-11-29 1997-04-22 Eastman Kodak Company Color photographic elements containing yellow colored magenta dye forming masking couplers
US5669967A (en) 1996-05-30 1997-09-23 Engelhard Corporation Pigment compositions
US5932546A (en) 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
SE9701398D0 (sv) 1997-04-15 1997-04-15 Astra Pharma Prod Novel compounds
GB9715830D0 (en) 1997-07-25 1997-10-01 Basf Ag Reactive dyes containing piperazine
WO1999011262A1 (en) 1997-09-02 1999-03-11 Roche Diagnostics Gmbh Mpl-receptor ligands, process for their preparation, medicaments containing them and their use for the treatment and prevention of thrombocytopaenia and anaemia
GB9718913D0 (en) 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
AU738473B2 (en) 1997-10-31 2001-09-20 Glaxosmithkline Llc Novel metal complexes
DE19851389A1 (de) 1998-11-07 2000-05-11 Dystar Textilfarben Gmbh & Co Gelbe Farbstoffmischungen von wasserlöslichen faserreaktiven Azofarbstoffen und ihre Verwendung
GC0000177A (en) 1998-12-17 2006-03-29 Smithkline Beecham Thrombopoietin mimetics
CO5210907A1 (es) 1999-05-12 2002-10-30 Novartis Ag Solvatos de pometrozina, insecticidamente activos, composiciones que contienen estos compuestos y metodos tanto para producir dichos compuestos y composiciones como para controlar plagas animales con estas composiciones
KR20020069183A (ko) 1999-07-26 2002-08-29 시오노기세이야쿠가부시키가이샤 트롬보포이에틴 작동성을 나타내는 의약 조성물
JP4488663B2 (ja) 1999-09-10 2010-06-23 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー トロンボポイエチン模倣物
WO2001021180A1 (en) 1999-09-24 2001-03-29 Smithkline Beecham Corporation Thrombopoietin mimetics
JP2003513965A (ja) 1999-11-05 2003-04-15 スミスクライン・ビーチャム・コーポレイション セミカルバゾン誘導体およびそれらのトロンボポエチン模倣物としての使用
ES2160560T1 (es) 1999-11-10 2001-11-16 Curacyte Ag Colorantes o,o'-dihidroxi-azoicos como constituyentes de medicamentos para el tratamiento de trombopenias.
TWI284639B (en) 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
US6214813B1 (en) 2000-04-07 2001-04-10 Kinetek Pharmaceuticals, Inc. Pyrazole compounds
HUP0001417A2 (hu) 2000-04-07 2002-12-28 Sanofi-Synthelabo Gyógyászatilag alkalmazható új sók, eljárás előállításukra és azokat tartalmazó gyógyászati készítmények
US6436915B1 (en) 2000-04-07 2002-08-20 Kinetek Pharmaceuticals, Inc. Pyrazole compounds
CY2010012I2 (el) * 2000-05-25 2020-05-29 Novartis Ag Μιμητικα θρομβοποιητινης
CA2436288A1 (en) 2000-12-19 2002-06-27 Smithkline Beecham Corporation Thrombopoietin mimetics
CA2432800A1 (en) 2000-12-21 2002-07-25 Smithkline Beecham Corporation Regulated activation of cell-membrane receptors by metal-chelating agonists
WO2002059099A1 (en) 2001-01-26 2002-08-01 Shionogi & Co., Ltd. Cyclic compounds having thrombopoietin receptor agonism
JP4145655B2 (ja) 2001-01-26 2008-09-03 塩野義製薬株式会社 トロンボポエチン受容体アゴニスト作用を有するハロゲン化合物
WO2002085343A1 (en) 2001-03-01 2002-10-31 Smithkline Beecham Corporation Thrombopoietin mimetics
JP3927001B2 (ja) 2001-06-15 2007-06-06 三菱化学株式会社 色素セット、インクセット並びに記録方法
WO2003045379A1 (en) 2001-11-30 2003-06-05 Kinetek Pharmaceuticals, Inc. Hydrazonopyrazole derivatives and their use as therapeutics
US20040176372A1 (en) 2002-03-01 2004-09-09 Pintex Pharmaceuticals, Inc. Pin1-modulating compounds and methods of use thereof
MY142390A (en) * 2002-05-22 2010-11-30 Glaxosmithkline Llc 3' - [(2z)-[1-(3,4-dimethylphenyl)-1,5- dihydro-3- methyl-5-0xo-4h-pyrazol-4- ylidene]hydrazino]-2' -hydroxy -[1,1' -biphenyl]-3-carboxylic acid bis-(monoethanolamine)
WO2003103686A1 (en) 2002-06-06 2003-12-18 Smithkline Beecham Corporation Thrombopoietin mimetics
AU2003268687A1 (en) 2002-09-30 2004-04-19 Yamanouchi Pharmaceutical Co., Ltd. Novel salt of 2-acylaminothiazole derivative
JP2006514951A (ja) 2002-12-13 2006-05-18 スミスクライン・ビーチャム・コーポレイション トロンボポエチン模倣物
US20070105824A1 (en) 2003-04-29 2007-05-10 Erickson-Miller Connie L Methods for treating degenerative diseases/injuries
TW200526638A (en) 2003-10-22 2005-08-16 Smithkline Beecham Corp 2-(3,4-dimethylphenyl)-4-{[2-hydroxy-3'-(1H-tetrazol-5-yl)biphenyl-3-yl]-hydrazono}-5-methyl-2,4-dihydropyrazol-3-one choline
MX2008003054A (es) * 2005-08-31 2008-03-25 Centocor Inc Lineas de celulas hospederas para la produccion de la region constante de anticuerpos, con fusion efectora mejorada.
JP2009521472A (ja) * 2005-12-22 2009-06-04 シェーリング コーポレイション 心肺手術の合併症の予防としてのトロンビンレセプターアンタゴニスト
WO2008073864A1 (en) 2006-12-12 2008-06-19 Smithkline Beecham Corporation Novel combinations
UY30915A1 (es) 2007-02-16 2008-09-02 Smithkline Beecham Corp Método de tratamiento de canceres
ECSP077628A (es) 2007-05-03 2008-12-30 Smithkline Beechman Corp Nueva composición farmacéutica
WO2009151862A1 (en) 2008-05-15 2009-12-17 Smithkline Beecham Corporation Method of treatment
WO2010045310A1 (en) 2008-10-16 2010-04-22 Glaxosmithkline Llc Method of treating thrombocytopenia
JP2012526137A (ja) 2009-05-07 2012-10-25 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 血小板減少症を治療する方法
PL3127427T3 (pl) 2009-05-29 2020-06-15 Novartis Ag Sposoby podawania związków agonistów trombopoetyny
JP6999080B2 (ja) 2015-04-11 2022-02-04 株式会社アーティエンス・ラボ 画像認識システム、画像認識方法、ホログラム記録媒体、ホログラム再生装置および画像撮影装置

Also Published As

Publication number Publication date
BRPI1014548A2 (pt) 2015-08-25
JP2012528184A (ja) 2012-11-12
AU2010254046B2 (en) 2013-10-10
EP2434894A4 (en) 2013-02-20
ZA201108374B (en) 2012-07-25
JP2017226668A (ja) 2017-12-28
HUE049075T2 (hu) 2020-08-28
IL216365A0 (en) 2012-01-31
EA024557B1 (ru) 2016-09-30
JP2016020360A (ja) 2016-02-04
EP3127427B1 (en) 2020-01-08
SG176088A1 (en) 2011-12-29
US20120064036A1 (en) 2012-03-15
SI3127427T1 (sl) 2020-07-31
PT3127427T (pt) 2020-04-17
DK3127427T3 (da) 2020-04-06
PL3127427T3 (pl) 2020-06-15
IL216365A (en) 2015-09-24
EP2434894A1 (en) 2012-04-04
AU2010254046C1 (en) 2014-03-06
ES2782898T3 (es) 2020-09-16
ES2605593T3 (es) 2017-03-15
CA2763768A1 (en) 2010-12-02
EA201690401A1 (ru) 2016-06-30
EP3127427A1 (en) 2017-02-08
AU2010254046A1 (en) 2011-12-08
EA201171462A1 (ru) 2012-05-30
PL2434894T3 (pl) 2017-04-28
US8609693B2 (en) 2013-12-17
CN104173337A (zh) 2014-12-03
WO2010138656A1 (en) 2010-12-02
PT2434894T (pt) 2016-11-29
KR20120015355A (ko) 2012-02-21
CN102458120A (zh) 2012-05-16
EP2434894B1 (en) 2016-08-31

Similar Documents

Publication Publication Date Title
EA201290833A1 (ru) Применение амисульприда в качестве противорвотного средства
GB201111485D0 (en) Drug composition and its use in therapy
MX2014014337A (es) Metodo de produccion de alta concentracion de celulas madre.
MX2011007589A (es) Tratamiento de un cancer usando una combinacion de bendamustine y un anticuerpo anti-cd20.
MX2012007806A (es) Composiciones farmaceuticas para administracion oral de peptidos de insulina.
MX2010010026A (es) Agente para tratar enfermedad.
MX2013012253A (es) Conjugados novedosos de aglutinante-farmaco (adc) y su uso.
NZ620326A (en) Cd37 immunotherapeutic combination therapies and uses thereof
NZ625440A (en) Anti-cxcr1 compositions and methods
UA108885C2 (uk) Композиція рисперидону для ін'єкційної депо-форми
MX2013014849A (es) 1-piperazino-3-fenil-indanos deuterados para el tratamiento de esquizofrenia.
MX2010008280A (es) Composicion para estimular la actividad de celula asesina natural.
SG179069A1 (en) Cancer stem cell-targeted and drug resistant cancer therapy
MX363549B (es) Composiciones farmacéuticas sólidas antidiabéticas.
MX2011012668A (es) Metodos de administracion de compuestos agonistas de trombopoyetina.
NZ604009A (en) A combination composition comprising ibuprofen and paracetamol
PH12013501896A1 (en) Use of a sprayable composition comprising ambroxol
UA55885U (ru) Способ коррекции повышенной агрегации тромбоцитов у больных гипертонической болезнью низкого и умеренного дополнительного риска
UA48009U (ru) Способ лечения пациентов с дисфункцией сфинктера одди
UA36393U (ru) Средство "панкреофил" для лечения и профилактики желудочно-кишечных заболеваний
UA38340U (ru) Способ лечения женщин с патологическим прелиминарным периодом
UA59660U (ru) Способ коррекции нарушений перекисных процессов в организме
UA44140U (en) Metallic nanoparticle
UA53280U (ru) Способ лечения больных стабильной стенокардией напряжения
UA46330U (ru) Способ назначения монотерапии пролонгированными гипотензивными средствами больным метаболическим синдромом

Legal Events

Date Code Title Description
FG Grant or registration