MX2011011329A - Forma de cristal novedosa de compuesto de benzopirano triciclico y metodo de reproduccion de la misma. - Google Patents
Forma de cristal novedosa de compuesto de benzopirano triciclico y metodo de reproduccion de la misma.Info
- Publication number
- MX2011011329A MX2011011329A MX2011011329A MX2011011329A MX2011011329A MX 2011011329 A MX2011011329 A MX 2011011329A MX 2011011329 A MX2011011329 A MX 2011011329A MX 2011011329 A MX2011011329 A MX 2011011329A MX 2011011329 A MX2011011329 A MX 2011011329A
- Authority
- MX
- Mexico
- Prior art keywords
- processes
- crystal forms
- solvent
- producing same
- novel crystal
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 4
- -1 benzopyran compound Chemical class 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 abstract 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002168 ethanoic acid esters Chemical class 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Se describen formas de cristal de (3R, 4S)-7-hidroximetil-2,2,9-tr imetil-4-(fenetilamino)-3 4-dihidro-2H-pirano(2,3-g]quinolin-3-ol que es una excelente medicina, y un proceso para producir las formas de cristal. El método comprende cristalizar (3R, 4S)-7-hidroximetil-2,2,9-trimetil-4-(fenetilamino)-3,4-dihidro-2H -pirano[2,3-g]quinolin-3-ol a partir de un solvente de éster de ácido acético, un solvente de hidrocarburo alifático, un solvente de nitrilo, un solvente de hidrocarburo aromático, un solvente de cetona o un solvente de éter. Se obtienen las formas de cristal por los procesos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009111281 | 2009-04-30 | ||
| PCT/JP2010/057698 WO2010126138A1 (ja) | 2009-04-30 | 2010-04-30 | ３環性ベンゾピラン化合物の新規な結晶形態及びその製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2011011329A true MX2011011329A (es) | 2011-11-18 |
| MX340918B MX340918B (es) | 2016-07-20 |
Family
ID=43032280
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011011329A MX340918B (es) | 2009-04-30 | 2010-04-30 | Forma de cristal novedosa de compuesto de benzopirano triciclico y metodo de produccion de la misma. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9242992B2 (es) |
| EP (1) | EP2426133B1 (es) |
| JP (1) | JP5664870B2 (es) |
| KR (1) | KR101703202B1 (es) |
| CN (1) | CN102414213B (es) |
| AR (1) | AR076524A1 (es) |
| AU (1) | AU2010242339B2 (es) |
| BR (1) | BRPI1007112A2 (es) |
| CA (1) | CA2759073C (es) |
| ES (1) | ES2562027T3 (es) |
| IL (1) | IL215930A (es) |
| MX (1) | MX340918B (es) |
| NZ (1) | NZ596060A (es) |
| PL (1) | PL2426133T3 (es) |
| RU (1) | RU2523279C2 (es) |
| SG (1) | SG175377A1 (es) |
| TW (1) | TWI480281B (es) |
| UA (1) | UA105385C2 (es) |
| WO (1) | WO2010126138A1 (es) |
| ZA (1) | ZA201107662B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220071951A1 (en) | 2018-12-28 | 2022-03-10 | Osaka University | Therapeutic agent for inherited bradyarrhythmia |
| KR102819183B1 (ko) | 2019-03-29 | 2025-06-13 | 한미약품 주식회사 | 퓨로피리미딘 화합물의 산 부가염의 결정형 |
| EP4083040A4 (en) | 2020-01-21 | 2024-04-24 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | IRAQ4 INHIBITOR CRYSTAL AND PREPARATION METHOD THEREFOR |
| JP7733887B2 (ja) * | 2020-06-26 | 2025-09-04 | 国立大学法人大阪大学 | 薬剤誘発性徐脈および徐脈性不整脈治療薬 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2446497A1 (de) * | 1974-09-28 | 1976-04-08 | Boehringer Sohn Ingelheim | 4-oxo-4h-pyrano- eckige klammer auf 3,2-c eckige klammer zu -chinolin-2-carbonsaeuren und ihre salze |
| US5164509A (en) * | 1990-11-26 | 1992-11-17 | E. R. Squibb & Sons, Inc. | Benzodiazolo analogs |
| GB9224169D0 (en) * | 1992-11-18 | 1993-01-06 | Lilly Industries Ltd | Pharmaceutical compounds |
| KR960700713A (ko) * | 1993-04-02 | 1996-02-24 | 도쿠시마 슈이치 | 심부전증 치료약(medicines for cardiac insufficiency) |
| EP0807629B1 (de) * | 1996-05-15 | 2004-03-03 | Aventis Pharma Deutschland GmbH | Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| EP0918774B9 (en) * | 1996-06-27 | 2002-04-10 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
| UA91189C2 (en) * | 2004-03-23 | 2010-07-12 | Ниссан Кемикал Индастриз, Лтд. | Tricyclic benzopyran compound as anti-arrhythmic agents |
-
2010
- 2010-04-30 PL PL10769836T patent/PL2426133T3/pl unknown
- 2010-04-30 CA CA2759073A patent/CA2759073C/en active Active
- 2010-04-30 ES ES10769836.7T patent/ES2562027T3/es active Active
- 2010-04-30 UA UAA201114121A patent/UA105385C2/uk unknown
- 2010-04-30 TW TW099113885A patent/TWI480281B/zh active
- 2010-04-30 JP JP2011511472A patent/JP5664870B2/ja active Active
- 2010-04-30 WO PCT/JP2010/057698 patent/WO2010126138A1/ja not_active Ceased
- 2010-04-30 AR ARP100101484A patent/AR076524A1/es not_active Application Discontinuation
- 2010-04-30 MX MX2011011329A patent/MX340918B/es active IP Right Grant
- 2010-04-30 BR BRPI1007112-1A patent/BRPI1007112A2/pt active Search and Examination
- 2010-04-30 NZ NZ596060A patent/NZ596060A/xx unknown
- 2010-04-30 KR KR1020117028198A patent/KR101703202B1/ko active Active
- 2010-04-30 US US13/318,230 patent/US9242992B2/en active Active
- 2010-04-30 EP EP10769836.7A patent/EP2426133B1/en active Active
- 2010-04-30 AU AU2010242339A patent/AU2010242339B2/en not_active Ceased
- 2010-04-30 SG SG2011079126A patent/SG175377A1/en unknown
- 2010-04-30 CN CN201080018858.0A patent/CN102414213B/zh active Active
- 2010-04-30 RU RU2011148595/04A patent/RU2523279C2/ru active
-
2011
- 2011-10-19 ZA ZA2011/07662A patent/ZA201107662B/en unknown
- 2011-10-25 IL IL215930A patent/IL215930A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010242339B2 (en) | 2015-10-01 |
| TWI480281B (zh) | 2015-04-11 |
| ZA201107662B (en) | 2012-12-27 |
| UA105385C2 (uk) | 2014-05-12 |
| NZ596060A (en) | 2012-12-21 |
| IL215930A (en) | 2016-09-29 |
| HK1166501A1 (en) | 2012-11-02 |
| EP2426133A4 (en) | 2013-01-09 |
| TW201111387A (en) | 2011-04-01 |
| KR20120024655A (ko) | 2012-03-14 |
| RU2011148595A (ru) | 2013-06-10 |
| AR076524A1 (es) | 2011-06-15 |
| US20120059169A1 (en) | 2012-03-08 |
| CN102414213A (zh) | 2012-04-11 |
| BRPI1007112A2 (pt) | 2015-08-18 |
| SG175377A1 (en) | 2011-12-29 |
| RU2523279C2 (ru) | 2014-07-20 |
| AU2010242339A1 (en) | 2011-11-17 |
| PL2426133T3 (pl) | 2016-04-29 |
| US9242992B2 (en) | 2016-01-26 |
| CN102414213B (zh) | 2014-12-24 |
| JP5664870B2 (ja) | 2015-02-04 |
| EP2426133B1 (en) | 2015-12-16 |
| CA2759073C (en) | 2017-03-14 |
| CA2759073A1 (en) | 2010-11-04 |
| IL215930A0 (en) | 2011-12-29 |
| JPWO2010126138A1 (ja) | 2012-11-01 |
| MX340918B (es) | 2016-07-20 |
| ES2562027T3 (es) | 2016-03-02 |
| KR101703202B1 (ko) | 2017-02-06 |
| EP2426133A1 (en) | 2012-03-07 |
| WO2010126138A1 (ja) | 2010-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |