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MX2010011154A - Tiazolopiridin-2-iloxi-fenilo y tiazolopirazin-2-iloxifenilaminas como moduladores de la leucotrieno a4 hidrolasa. - Google Patents

Tiazolopiridin-2-iloxi-fenilo y tiazolopirazin-2-iloxifenilaminas como moduladores de la leucotrieno a4 hidrolasa.

Info

Publication number
MX2010011154A
MX2010011154A MX2010011154A MX2010011154A MX2010011154A MX 2010011154 A MX2010011154 A MX 2010011154A MX 2010011154 A MX2010011154 A MX 2010011154A MX 2010011154 A MX2010011154 A MX 2010011154A MX 2010011154 A MX2010011154 A MX 2010011154A
Authority
MX
Mexico
Prior art keywords
yloxy
phenyl
thiazolopyrazin
thiazolopyridin
modulators
Prior art date
Application number
MX2010011154A
Other languages
English (en)
Inventor
Laurent Gomez
Xiaohu Deng
Jimmy T Liang
Anne M Fourie
Cheryl A Grice
John J M Wiener
Aaron M Kearney
Genesis M Bacani
Alice Lee-Dutra
Diego Broggini
Eugene Y Cheung
Christa C Chrovian
Alvah T Wickboldt
Hartmut Zinser
Adrienne M Landry-Bayle
Susanne Lochner
Neelakandha S Mani
Alejandro Santillan Jr
Kathleen C Sappey
Kia Sepassi
Virginia M Tanis
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MX2010011154A publication Critical patent/MX2010011154A/es

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    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
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    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se describen compuestos de tiazolopiridin-2-iloxi-fenilo y tiazolopirazin-2-iloxi-fenilamina, los cuales son útiles como moduladores de LTA4 hidrolasa (LTA4H); dichos compuestos pueden usarse en composiciones farmacéuticas y métodos para la modulación de LTA4H y para el tratamiento de estados de enfermedad, trastornos y condiciones mediadas por la actividad de LTA4 hidrolasa.
MX2010011154A 2008-04-11 2009-04-09 Tiazolopiridin-2-iloxi-fenilo y tiazolopirazin-2-iloxifenilaminas como moduladores de la leucotrieno a4 hidrolasa. MX2010011154A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4434908P 2008-04-11 2008-04-11
US14912909P 2009-02-02 2009-02-02
PCT/US2009/040070 WO2009126806A2 (en) 2008-04-11 2009-04-09 Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase

Publications (1)

Publication Number Publication Date
MX2010011154A true MX2010011154A (es) 2010-12-21

Family

ID=41130551

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010011154A MX2010011154A (es) 2008-04-11 2009-04-09 Tiazolopiridin-2-iloxi-fenilo y tiazolopirazin-2-iloxifenilaminas como moduladores de la leucotrieno a4 hidrolasa.

Country Status (35)

Country Link
US (3) US7939527B2 (es)
EP (2) EP2268646B9 (es)
JP (2) JP5530423B2 (es)
KR (1) KR101228378B1 (es)
CN (1) CN102056933B (es)
AR (1) AR072353A1 (es)
AU (1) AU2009234140B2 (es)
BR (1) BRPI0911336A2 (es)
CA (1) CA2721099C (es)
CL (1) CL2009000877A1 (es)
CO (1) CO6260069A2 (es)
CY (1) CY1114628T1 (es)
DK (2) DK2268646T3 (es)
EA (1) EA018802B1 (es)
EC (1) ECSP10010558A (es)
ES (2) ES2440746T3 (es)
HN (1) HN2010002074A (es)
HR (2) HRP20131192T1 (es)
IL (2) IL208480A (es)
JO (1) JO2911B1 (es)
MX (1) MX2010011154A (es)
MY (1) MY157597A (es)
NI (1) NI201000168A (es)
NZ (2) NZ588341A (es)
PE (1) PE20091779A1 (es)
PH (1) PH12013500094B1 (es)
PL (2) PL2336125T3 (es)
PT (2) PT2336125E (es)
RS (2) RS52712B (es)
SI (2) SI2336125T1 (es)
SV (1) SV2010003694A (es)
TW (2) TWI461196B (es)
UY (1) UY31760A (es)
WO (1) WO2009126806A2 (es)
ZA (1) ZA201008054B (es)

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