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MX2010009670A - Conjugados de paclitaxel polimericos y metodos para tratamiento de cancer. - Google Patents

Conjugados de paclitaxel polimericos y metodos para tratamiento de cancer.

Info

Publication number
MX2010009670A
MX2010009670A MX2010009670A MX2010009670A MX2010009670A MX 2010009670 A MX2010009670 A MX 2010009670A MX 2010009670 A MX2010009670 A MX 2010009670A MX 2010009670 A MX2010009670 A MX 2010009670A MX 2010009670 A MX2010009670 A MX 2010009670A
Authority
MX
Mexico
Prior art keywords
methods
treating cancer
cancer
paclitaxel conjugates
polymer paclitaxel
Prior art date
Application number
MX2010009670A
Other languages
English (en)
Inventor
Gang Zhao
Lei Yu
Xinghe Wang
Van Sang
Zhongling Feng
Original Assignee
Nitto Denko Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitto Denko Corp filed Critical Nitto Denko Corp
Publication of MX2010009670A publication Critical patent/MX2010009670A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describen composiciones farmacéuticas que comprenden un conjugado de PGGA-PTX. Las composiciones farmacéuticas son usadas para tratar una variedad de cánceres, tales como cáncer de pulmón, cáncer de piel, cáncer de riñón, cáncer de hígado y cáncer de bazo.
MX2010009670A 2008-03-06 2009-02-26 Conjugados de paclitaxel polimericos y metodos para tratamiento de cancer. MX2010009670A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3442308P 2008-03-06 2008-03-06
US4421408P 2008-04-11 2008-04-11
PCT/US2009/035335 WO2009111271A1 (en) 2008-03-06 2009-02-26 Polymer paclitaxel conjugates and methods for treating cancer

Publications (1)

Publication Number Publication Date
MX2010009670A true MX2010009670A (es) 2010-09-22

Family

ID=40810091

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010009670A MX2010009670A (es) 2008-03-06 2009-02-26 Conjugados de paclitaxel polimericos y metodos para tratamiento de cancer.

Country Status (11)

Country Link
US (1) US20090226393A1 (es)
EP (1) EP2262537A1 (es)
JP (1) JP2011513412A (es)
KR (1) KR20100122510A (es)
CN (2) CN104096236A (es)
AU (1) AU2009222230A1 (es)
CA (1) CA2716662A1 (es)
MX (1) MX2010009670A (es)
RU (1) RU2010137032A (es)
TW (1) TW200940053A (es)
WO (1) WO2009111271A1 (es)

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US8197828B2 (en) * 2007-05-09 2012-06-12 Nitto Denko Corporation Compositions that include a hydrophobic compound and a polyamino acid conjugate
RU2011117935A (ru) * 2008-10-15 2012-11-27 Нитто Денко Корпорейшн Способ получения конъюгатов полиглутаматов
BR112012013305A2 (pt) * 2009-12-16 2016-03-01 Nitto Denko Corp processos para a preparação de ácido poliglutâmico
US20110224148A1 (en) * 2010-03-11 2011-09-15 Nitto Denko Corporation Carbohydrate-polyamino acid-drug conjugates
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Also Published As

Publication number Publication date
CN102083468A (zh) 2011-06-01
AU2009222230A1 (en) 2009-09-11
JP2011513412A (ja) 2011-04-28
CN104096236A (zh) 2014-10-15
WO2009111271A1 (en) 2009-09-11
TW200940053A (en) 2009-10-01
RU2010137032A (ru) 2012-04-20
CA2716662A1 (en) 2009-03-11
EP2262537A1 (en) 2010-12-22
US20090226393A1 (en) 2009-09-10
KR20100122510A (ko) 2010-11-22

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