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MX2010006425A - Moduladores de proteina cinasa de objetivos multiples 1,3-ciclopentadiona-substituida de cancer, angiogenesis y las trayectorias inflamatorias asociadas con los mismos. - Google Patents

Moduladores de proteina cinasa de objetivos multiples 1,3-ciclopentadiona-substituida de cancer, angiogenesis y las trayectorias inflamatorias asociadas con los mismos.

Info

Publication number
MX2010006425A
MX2010006425A MX2010006425A MX2010006425A MX2010006425A MX 2010006425 A MX2010006425 A MX 2010006425A MX 2010006425 A MX2010006425 A MX 2010006425A MX 2010006425 A MX2010006425 A MX 2010006425A MX 2010006425 A MX2010006425 A MX 2010006425A
Authority
MX
Mexico
Prior art keywords
angiogenesis
substituted
cyclopentadione
protein kinase
cancer
Prior art date
Application number
MX2010006425A
Other languages
English (en)
Inventor
Veera Konda
Anu Desai
Jeffrey S Bland
Matthew L Tripp
John G Babish
Gary Darland
Brian Carroll
James Traub
Linda M Pacioretty
Dennis Emma
Original Assignee
Metaproteomics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metaproteomics Llc filed Critical Metaproteomics Llc
Publication of MX2010006425A publication Critical patent/MX2010006425A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describen compuestos y métodos para la modulación de proteína cinasa de objetivos múltiples para el tratamiento de angiogénesis, cáncer, o las trayectorias inflamatorias asociadas con esas condiciones. Los compuestos y métodos descritos se basan en compuestos 1,3-ciclopentadiona-substituidos.
MX2010006425A 2007-12-10 2008-12-10 Moduladores de proteina cinasa de objetivos multiples 1,3-ciclopentadiona-substituida de cancer, angiogenesis y las trayectorias inflamatorias asociadas con los mismos. MX2010006425A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1250607P 2007-12-10 2007-12-10
PCT/US2008/086208 WO2009076428A1 (en) 2007-12-10 2008-12-10 Substituted 1,3-cyclopentadione multi-target protein kinase modulators of cancer, angiogenesis and the inflammatory pathways associated therewith

Publications (1)

Publication Number Publication Date
MX2010006425A true MX2010006425A (es) 2010-08-31

Family

ID=40755859

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010006425A MX2010006425A (es) 2007-12-10 2008-12-10 Moduladores de proteina cinasa de objetivos multiples 1,3-ciclopentadiona-substituida de cancer, angiogenesis y las trayectorias inflamatorias asociadas con los mismos.

Country Status (10)

Country Link
US (1) US20100137449A1 (es)
EP (1) EP2229178A4 (es)
JP (1) JP2011506464A (es)
KR (1) KR20100131969A (es)
CN (1) CN101969972A (es)
AU (1) AU2008335156A1 (es)
CA (1) CA2708613A1 (es)
MX (1) MX2010006425A (es)
WO (1) WO2009076428A1 (es)
ZA (1) ZA201004687B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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CA2853974C (en) * 2010-10-30 2020-11-10 Kindex Therapeutics, Llc Cis 3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one derivatives, substantially enantiomerically pure compositions and methods
WO2015017549A1 (en) 2013-07-30 2015-02-05 University Of South Florida (A Florida Non-Profit Corporation) Treating an atypical protein kinase c enzyme abnormality
MA54907A (fr) * 2019-02-06 2022-05-11 Venthera Inc Inhibiteurs de phosphoinositide 3-kinase topiques
CN114452392B (zh) * 2022-02-07 2024-06-18 孙良丹 用于抑制camk2g表达的制剂在制备用于治疗银屑病的药剂中的应用

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Also Published As

Publication number Publication date
JP2011506464A (ja) 2011-03-03
US20100137449A1 (en) 2010-06-03
AU2008335156A1 (en) 2009-06-18
ZA201004687B (en) 2011-03-30
KR20100131969A (ko) 2010-12-16
WO2009076428A1 (en) 2009-06-18
EP2229178A1 (en) 2010-09-22
CN101969972A (zh) 2011-02-09
CA2708613A1 (en) 2009-06-18
EP2229178A4 (en) 2011-03-09

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