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MX2009001327A - Compuestos de indol. - Google Patents

Compuestos de indol.

Info

Publication number
MX2009001327A
MX2009001327A MX2009001327A MX2009001327A MX2009001327A MX 2009001327 A MX2009001327 A MX 2009001327A MX 2009001327 A MX2009001327 A MX 2009001327A MX 2009001327 A MX2009001327 A MX 2009001327A MX 2009001327 A MX2009001327 A MX 2009001327A
Authority
MX
Mexico
Prior art keywords
indole compounds
compounds
indole
derivatives
inflammation
Prior art date
Application number
MX2009001327A
Other languages
English (en)
Inventor
John Jeffrey Talley
Mark G Currie
Charles Kim
James Philip Pearson
G Todd Milne
Wayne Schairer
Jane Yang
Timothy Barden
Regina Lundrigan
Ara Mermerian
Kevin Sprott
Original Assignee
Ironwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ironwood Pharmaceuticals Inc filed Critical Ironwood Pharmaceuticals Inc
Publication of MX2009001327A publication Critical patent/MX2009001327A/es

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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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Abstract

La presente invención se refiere a derivados de indol que son de utilidad para tratar dolor, inflamación y otras afecciones patológicas. Algunos de los compuestos son derivados de bencilo y otros son derivados de benzoilo. Los compuestos están sustituidos al menos en la posición 3 del indol.
MX2009001327A 2006-08-07 2007-08-07 Compuestos de indol. MX2009001327A (es)

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WO2008019357A2 (en) 2008-02-14
EP2610244A1 (en) 2013-07-03
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NZ596024A (en) 2013-07-26
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WO2008019357A3 (en) 2008-08-21
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CA2660704A1 (en) 2008-02-14
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AU2007281747A1 (en) 2008-02-14

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