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MX2010001993A - Metodos y composiciones para diagnosticar una enfermedad. - Google Patents

Metodos y composiciones para diagnosticar una enfermedad.

Info

Publication number
MX2010001993A
MX2010001993A MX2010001993A MX2010001993A MX2010001993A MX 2010001993 A MX2010001993 A MX 2010001993A MX 2010001993 A MX2010001993 A MX 2010001993A MX 2010001993 A MX2010001993 A MX 2010001993A MX 2010001993 A MX2010001993 A MX 2010001993A
Authority
MX
Mexico
Prior art keywords
compositions
methods
disease
disorder
diagnosing disease
Prior art date
Application number
MX2010001993A
Other languages
English (en)
Inventor
Thomas D Reed
Robert P Beech
Robert Patzig
Original Assignee
Intrexon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intrexon Corp filed Critical Intrexon Corp
Publication of MX2010001993A publication Critical patent/MX2010001993A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders
    • G01N2800/245—Transplantation related diseases, e.g. graft versus host disease

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención se relaciona a métodos y composiciones para diagnosticar una enfermedad o trastorno en un sujeto por introducir en las células del sujeto una construcción de interruptor genético de diagnóstico y monitorear la expresión de un gen indicador. La invención además se relaciona a métodos y composiciones para monitorear la progresión de una enfermedad o trastorno o la efectividad de un tratamiento de una enfermedad o trastorno.
MX2010001993A 2007-08-23 2008-08-25 Metodos y composiciones para diagnosticar una enfermedad. MX2010001993A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95747407P 2007-08-23 2007-08-23
US1465407P 2007-12-18 2007-12-18
US4794008P 2008-04-25 2008-04-25
PCT/US2008/010040 WO2009025866A1 (en) 2007-08-23 2008-08-25 Methods and compositions for diagnosing disease

Publications (1)

Publication Number Publication Date
MX2010001993A true MX2010001993A (es) 2010-03-11

Family

ID=40378488

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010001993A MX2010001993A (es) 2007-08-23 2008-08-25 Metodos y composiciones para diagnosticar una enfermedad.

Country Status (11)

Country Link
US (5) US20090098055A1 (es)
EP (1) EP2185730A4 (es)
JP (1) JP2010536373A (es)
KR (1) KR20100049084A (es)
CN (1) CN101835908A (es)
AU (1) AU2008289461A1 (es)
CA (1) CA2698212A1 (es)
MX (1) MX2010001993A (es)
NZ (1) NZ583430A (es)
WO (1) WO2009025866A1 (es)
ZA (1) ZA201000983B (es)

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RU2524431C2 (ru) * 2007-09-26 2014-07-27 Интрексон Корпорейшн Синтетические 5 utr (нетранслируемые области), экспрессионные векторы и способ повышения трансгенной экспрессии
RU2499599C2 (ru) * 2007-09-28 2013-11-27 Интрексон Корпорейшн Конструкции терапевтического переключения генов и биореакторы для экспрессии биотерапевтических молекул и их применение
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CN105510586B (zh) * 2015-12-22 2017-09-12 湖北鹊景生物医学有限公司 用于肺癌诊断的试剂盒及其使用方法
CN111848733B (zh) * 2019-04-30 2024-03-12 上海细胞治疗集团有限公司 一种多肽组合物及疫苗
CN111848732B (zh) * 2019-04-30 2024-03-12 上海细胞治疗集团有限公司 多肽组合物及疫苗
CN110051841B (zh) * 2019-05-28 2021-02-02 北京大学 Nat10抑制剂在制备用于抑制hif表达的药物中的应用
CN111304226A (zh) * 2019-11-21 2020-06-19 福州福瑞医学检验实验室有限公司 一种编码cyp1b1基因突变体的核酸及其应用
RU2728683C1 (ru) * 2019-12-03 2020-07-30 Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО КубГМУ Минздрава России) Способ ранней диагностики отторжения трансплантата
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Also Published As

Publication number Publication date
EP2185730A4 (en) 2010-10-27
KR20100049084A (ko) 2010-05-11
CA2698212A1 (en) 2009-02-26
CN101835908A (zh) 2010-09-15
US20170145520A1 (en) 2017-05-25
NZ583430A (en) 2012-06-29
US9222121B2 (en) 2015-12-29
US20150056631A1 (en) 2015-02-26
WO2009025866A1 (en) 2009-02-26
US20160145688A1 (en) 2016-05-26
ZA201000983B (en) 2011-04-28
US20130266947A1 (en) 2013-10-10
JP2010536373A (ja) 2010-12-02
AU2008289461A1 (en) 2009-02-26
EP2185730A1 (en) 2010-05-19
US20090098055A1 (en) 2009-04-16
US9605316B2 (en) 2017-03-28

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