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MX2010001714A - Moduladores de canabinoides 5-vinilfenil-1-fenil-pirazol sustituidos. - Google Patents

Moduladores de canabinoides 5-vinilfenil-1-fenil-pirazol sustituidos.

Info

Publication number
MX2010001714A
MX2010001714A MX2010001714A MX2010001714A MX2010001714A MX 2010001714 A MX2010001714 A MX 2010001714A MX 2010001714 A MX2010001714 A MX 2010001714A MX 2010001714 A MX2010001714 A MX 2010001714A MX 2010001714 A MX2010001714 A MX 2010001714A
Authority
MX
Mexico
Prior art keywords
vinylphenyl
phenyl
substituted
cannabinoid modulators
pyrazole cannabinoid
Prior art date
Application number
MX2010001714A
Other languages
English (en)
Inventor
Meng Pan
Mingde Xia
Michael P Watcher
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MX2010001714A publication Critical patent/MX2010001714A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P3/00—Drugs for disorders of the metabolism
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    • A—HUMAN NECESSITIES
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)

Abstract

La presente invención está dirigida a un compuesto modulador de canabinoides de Fórmula (l): (ver fórmula l) o una forma de éste y a los métodos para su uso en tratar, mejorar o prevenir un síndrome, trastorno o enfermedad mediada(o) por receptores canabinoides.
MX2010001714A 2007-08-13 2008-08-12 Moduladores de canabinoides 5-vinilfenil-1-fenil-pirazol sustituidos. MX2010001714A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95541107P 2007-08-13 2007-08-13
PCT/US2008/072846 WO2009023653A2 (en) 2007-08-13 2008-08-12 Substituted 5-vinylphenyl-1-phenyl-pyrazole cannabinoid modulators

Publications (1)

Publication Number Publication Date
MX2010001714A true MX2010001714A (es) 2010-03-10

Family

ID=40351436

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010001714A MX2010001714A (es) 2007-08-13 2008-08-12 Moduladores de canabinoides 5-vinilfenil-1-fenil-pirazol sustituidos.

Country Status (12)

Country Link
US (2) US7943653B2 (es)
EP (1) EP2192900A4 (es)
JP (1) JP2011504167A (es)
KR (1) KR20100052532A (es)
CN (1) CN101969945A (es)
AU (1) AU2008286976A1 (es)
BR (1) BRPI0816154A2 (es)
CA (1) CA2696006A1 (es)
MX (1) MX2010001714A (es)
NZ (1) NZ583389A (es)
RU (1) RU2010109369A (es)
WO (1) WO2009023653A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7943653B2 (en) * 2007-08-13 2011-05-17 Janssen Pharmaceutica N.V. Substituted 5-vinylphenyl-1-phenyl-pyrazole cannabinoid modulators
US8227461B2 (en) * 2009-04-30 2012-07-24 Hoffmann-La Roche Inc. Isoxazoles
JP5460858B2 (ja) * 2009-05-05 2014-04-02 エフ．ホフマン−ラ ロシュ アーゲー イソオキサゾール−ピラゾール誘導体
US8859606B2 (en) 2010-07-01 2014-10-14 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
BR102017010169A2 (pt) * 2017-05-15 2019-02-26 Remer Consultores Assessoria Empresarial Ltda. composto, intermediário de síntese, uso na preparação de anticonvulsivante, composição farmacêutica anticonvulsivante
WO2020123855A1 (en) 2018-12-12 2020-06-18 University Of Washington Inhibitor compounds for male contraception

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2948718A (en) * 1960-08-09 New n-heterocyclic compounds
US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
JPS5625169A (en) * 1979-06-01 1981-03-10 Wellcome Found Triazine derivative
LU83729A1 (fr) * 1981-11-04 1983-09-01 Galephar Sels d'acide valproique,leur preparation et leur utilisation
US4513006A (en) * 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
EP0330678B1 (en) * 1987-01-05 1990-10-24 E.I. Du Pont De Nemours And Company Insecticidal pyrazolines
FR2665898B1 (fr) * 1990-08-20 1994-03-11 Sanofi Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5242942A (en) * 1992-04-28 1993-09-07 Mcneilab, Inc. Anticonvulsant fructopyranose cyclic sulfites and sulfates
US5384327A (en) * 1992-12-22 1995-01-24 Mcneilab, Inc. Anticonvulsant sorbopyranose sulfamates
AU2096895A (en) * 1994-03-07 1995-09-25 Sugen, Incorporated Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof
US6331555B1 (en) * 1995-06-01 2001-12-18 University Of California Treatment of platelet derived growth factor related disorders such as cancers
EP1223929B1 (en) * 1999-10-18 2006-08-23 The University Of Connecticut Cannabimimetic indole derivatives
US6900236B1 (en) * 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US7452997B2 (en) * 2004-03-24 2008-11-18 Janssen Pharmaceutica, N.V. Tetrahydro-indazole cannabinoid modulators
EP1937646A1 (en) * 2005-09-23 2008-07-02 Janssen Pharmaceutica N.V. Tetrahydro-cyclopentyl pyrazole cannabinoid modulators
WO2007038045A1 (en) * 2005-09-23 2007-04-05 Janssen Pharmaceutica, N.V. Tetrahydro-indazolyl cannabinoid modulators
US20070117858A1 (en) * 2005-11-23 2007-05-24 Mingde Xia Substituted 5-heteroaryl-1-phenyl-pyrazole cannabinoid modulators
US7943653B2 (en) * 2007-08-13 2011-05-17 Janssen Pharmaceutica N.V. Substituted 5-vinylphenyl-1-phenyl-pyrazole cannabinoid modulators

Also Published As

Publication number Publication date
RU2010109369A (ru) 2011-09-20
KR20100052532A (ko) 2010-05-19
US7943653B2 (en) 2011-05-17
US20110178148A1 (en) 2011-07-21
AU2008286976A1 (en) 2009-02-19
CN101969945A (zh) 2011-02-09
WO2009023653A3 (en) 2012-06-21
WO2009023653A2 (en) 2009-02-19
EP2192900A4 (en) 2013-04-10
NZ583389A (en) 2012-07-27
CA2696006A1 (en) 2009-02-19
US20090048235A1 (en) 2009-02-19
EP2192900A2 (en) 2010-06-09
BRPI0816154A2 (pt) 2015-02-18
JP2011504167A (ja) 2011-02-03

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