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MX2009013815A - Compuestos de quinazolinona y metodos de uso para los mismos. - Google Patents

Compuestos de quinazolinona y metodos de uso para los mismos.

Info

Publication number
MX2009013815A
MX2009013815A MX2009013815A MX2009013815A MX2009013815A MX 2009013815 A MX2009013815 A MX 2009013815A MX 2009013815 A MX2009013815 A MX 2009013815A MX 2009013815 A MX2009013815 A MX 2009013815A MX 2009013815 A MX2009013815 A MX 2009013815A
Authority
MX
Mexico
Prior art keywords
methods
present
compounds
quinazolinone
quinazolinone compounds
Prior art date
Application number
MX2009013815A
Other languages
English (en)
Inventor
Jifeng Liu
Syed M Ali
Mark A Ashwell
Ping Ye
Yousheng Guan
Shi-Chung Ng
Rocio Palma
Dan Yohannes
Original Assignee
Arqule Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arqule Inc filed Critical Arqule Inc
Publication of MX2009013815A publication Critical patent/MX2009013815A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a compuestos de quinazolinona, y métodos de preparación de estos compuestos; la presente invención también se refiere a composiciones farmacéuticas que comprenden los compuestos de quinazolinona; la presente invención proporciona métodos para tratar un trastorno proliferativo celular, tal como cáncer, al administrar a un sujeto en necesidad del mismo, una cantidad terapéuticamente efectiva de un compuesto de quinazolinona de la presente invención.
MX2009013815A 2007-06-22 2008-06-19 Compuestos de quinazolinona y metodos de uso para los mismos. MX2009013815A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94583807P 2007-06-22 2007-06-22
PCT/US2008/067571 WO2009002808A2 (en) 2007-06-22 2008-06-19 Quinazolinone compounds and methods of use thereof

Publications (1)

Publication Number Publication Date
MX2009013815A true MX2009013815A (es) 2010-03-01

Family

ID=39846620

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009013815A MX2009013815A (es) 2007-06-22 2008-06-19 Compuestos de quinazolinona y metodos de uso para los mismos.

Country Status (13)

Country Link
US (1) US8232285B2 (es)
EP (1) EP2173724B1 (es)
JP (1) JP2010530885A (es)
KR (1) KR20100024494A (es)
CN (1) CN101801937A (es)
AU (1) AU2008268613A1 (es)
BR (1) BRPI0813355A2 (es)
CA (1) CA2704282A1 (es)
IL (1) IL202740A0 (es)
MX (1) MX2009013815A (es)
TW (1) TW200918069A (es)
WO (1) WO2009002808A2 (es)
ZA (1) ZA201000183B (es)

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WO2015051241A1 (en) 2013-10-04 2015-04-09 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
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US9708348B2 (en) 2014-10-03 2017-07-18 Infinity Pharmaceuticals, Inc. Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof
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WO2017161116A1 (en) 2016-03-17 2017-09-21 Infinity Pharmaceuticals, Inc. Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
US10919914B2 (en) 2016-06-08 2021-02-16 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
TW201825465A (zh) 2016-09-23 2018-07-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201813963A (zh) 2016-09-23 2018-04-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201815787A (zh) 2016-09-23 2018-05-01 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
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Also Published As

Publication number Publication date
TW200918069A (en) 2009-05-01
WO2009002808A2 (en) 2008-12-31
US20090130097A1 (en) 2009-05-21
EP2173724A2 (en) 2010-04-14
CN101801937A (zh) 2010-08-11
CA2704282A1 (en) 2008-12-31
IL202740A0 (en) 2010-06-30
AU2008268613A1 (en) 2008-12-31
JP2010530885A (ja) 2010-09-16
ZA201000183B (en) 2011-03-30
KR20100024494A (ko) 2010-03-05
US8232285B2 (en) 2012-07-31
EP2173724B1 (en) 2012-12-05
BRPI0813355A2 (pt) 2014-12-30
WO2009002808A3 (en) 2009-07-23

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