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MX2009012085A - Métodos para la expansión dirigida de epítopes para el uso como ligandos de anticuerpos. - Google Patents

Métodos para la expansión dirigida de epítopes para el uso como ligandos de anticuerpos.

Info

Publication number
MX2009012085A
MX2009012085A MX2009012085A MX2009012085A MX2009012085A MX 2009012085 A MX2009012085 A MX 2009012085A MX 2009012085 A MX2009012085 A MX 2009012085A MX 2009012085 A MX2009012085 A MX 2009012085A MX 2009012085 A MX2009012085 A MX 2009012085A
Authority
MX
Mexico
Prior art keywords
epitopes
methods
antibodies
antibody ligands
directed expansion
Prior art date
Application number
MX2009012085A
Other languages
English (en)
Inventor
Dustan Bonnin
Original Assignee
Peptimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peptimmune Inc filed Critical Peptimmune Inc
Publication of MX2009012085A publication Critical patent/MX2009012085A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención comprende un procedimiento para seleccionar y elaborar anticuerpos útiles para propósitos terapéuticos, profilácticos, de diagnóstico o de investigación utilizando mezclas de epítopo péptido sintetizadas a través de síntesis de fase sólida, dicho procedimiento se define por un grupo de reglas con respecto a la identidad y la frecuencia de ocurrencia de aminoácidos que substituyen una base o aminoácido nativo de un epítopo conocido. Los anticuerpos resultantes están relacionados con, pero son distintos de, anticuerpos que se unen al epítopo conocido.
MX2009012085A 2007-05-07 2008-05-07 Métodos para la expansión dirigida de epítopes para el uso como ligandos de anticuerpos. MX2009012085A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US92822507P 2007-05-07 2007-05-07
US99928307P 2007-10-16 2007-10-16
US99928407P 2007-10-16 2007-10-16
US12468908P 2008-04-17 2008-04-17
PCT/US2008/005919 WO2009023047A2 (en) 2007-05-07 2008-05-07 Methods for the directed expansion of epitopes for use as antibody ligands

Publications (1)

Publication Number Publication Date
MX2009012085A true MX2009012085A (es) 2010-01-20

Family

ID=40351332

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012085A MX2009012085A (es) 2007-05-07 2008-05-07 Métodos para la expansión dirigida de epítopes para el uso como ligandos de anticuerpos.

Country Status (11)

Country Link
US (1) US20100298547A1 (es)
EP (1) EP2157980A2 (es)
JP (1) JP2010540410A (es)
KR (1) KR20100019487A (es)
CN (1) CN101848731A (es)
AU (1) AU2008287530A1 (es)
BR (1) BRPI0811293A2 (es)
CA (1) CA2686817A1 (es)
IL (1) IL201997A0 (es)
MX (1) MX2009012085A (es)
WO (1) WO2009023047A2 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP3467A (en) 2007-10-16 2015-11-30 Peptimmune Inc Methods for designing and preparing vaccines comprising directed sequence polymer compositions via the directed expansion of epitopes
US8546532B2 (en) * 2008-04-17 2013-10-01 Declion Pharmaceuticals, Inc. Synthesis of directed sequence polymer compositions and antibodies thereof for the treatment of protein conformational disorders
US8389689B2 (en) * 2009-10-28 2013-03-05 Janssen Biotech, Inc. Anti-GLP-1R antibodies and their uses
KR101694523B1 (ko) 2015-07-01 2017-01-23 박성진 위험을 알리는 cctv 카메라용 브라켓
CN111363043B (zh) * 2020-04-09 2021-07-23 福州迈新生物技术开发有限公司 抗cd20蛋白单克隆抗体、细胞系及其制备方法和应用
CN112661816B (zh) * 2021-01-13 2022-10-11 江西省人民医院 用于利妥昔单抗血药浓度检测的人工抗原及试剂盒

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5859204A (en) * 1992-04-07 1999-01-12 Emory University Modified factor VIII
PT735893E (pt) * 1993-09-14 2009-03-06 Pharmexa Inc Péptidos que se ligam aos alelos pan dr para aumentar a resposta imunitária
US6093396A (en) * 1996-09-27 2000-07-25 Diamyd Therapeutics Ab Modified glutamic acid decarboxylase (GAD)
FR2765688B1 (fr) * 1997-07-04 1999-09-10 Pasteur Institut Reactif de detection et de suivi des infections provoquees par le virus d'epstein-barr et ses applications
US6541011B2 (en) * 1998-02-11 2003-04-01 Maxygen, Inc. Antigen library immunization
US7118874B2 (en) * 1998-10-09 2006-10-10 Variation Biotechnologies Inc. Immunogenic formulation and process for preparation thereof
WO2002059143A2 (en) * 2001-01-24 2002-08-01 President And Fellows Of Harvard College Therapeutic peptides for demyelinating conditions
JP2004085206A (ja) * 2002-08-22 2004-03-18 Ajinomoto Co Inc タンパク質間の相互作用界面情報を用いた疾患関連アミノ酸残基の特定方法およびそれを用いた薬物スクリーニング法
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
DE102004041964B4 (de) * 2004-08-04 2012-04-26 Schaeffler Technologies Gmbh & Co. Kg Maschinenelement für Wälzbelastung
EP1676859A1 (en) * 2004-12-30 2006-07-05 Pevion Biotech Ltd. Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide
US20090104216A1 (en) * 2005-06-01 2009-04-23 Variation Biotechnologies, Inc. Peptide-Based Influenza Vaccine Formulation
US20090162383A1 (en) * 2006-12-26 2009-06-25 Padlan Eduardo A Method for designing vaccines against constantly mutating pathogens

Also Published As

Publication number Publication date
IL201997A0 (en) 2010-06-16
EP2157980A2 (en) 2010-03-03
AU2008287530A1 (en) 2009-02-19
WO2009023047A3 (en) 2009-05-28
US20100298547A1 (en) 2010-11-25
BRPI0811293A2 (pt) 2017-05-16
CA2686817A1 (en) 2009-02-19
KR20100019487A (ko) 2010-02-18
JP2010540410A (ja) 2010-12-24
CN101848731A (zh) 2010-09-29
WO2009023047A2 (en) 2009-02-19

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Legal Events

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