MX2009009200A - Tratamiento de enfermedades caracterizadas por la inflamacion. - Google Patents
Tratamiento de enfermedades caracterizadas por la inflamacion.Info
- Publication number
- MX2009009200A MX2009009200A MX2009009200A MX2009009200A MX2009009200A MX 2009009200 A MX2009009200 A MX 2009009200A MX 2009009200 A MX2009009200 A MX 2009009200A MX 2009009200 A MX2009009200 A MX 2009009200A MX 2009009200 A MX2009009200 A MX 2009009200A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- inflammation
- diseases characterized
- methods
- pathway
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 230000024203 complement activation Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000037361 pathway Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/472—Complement proteins, e.g. anaphylatoxin, C3a, C5a
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Ophthalmology & Optometry (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
Abstract
La invención proporciona, en parte, métodos, ácidos nucleicos, vectores, proteínas y moléculas de enlace que se pueden utilizar para modular una vía tal como una vía del complemento. Estos métodos y composiciones se pueden utilizar, inter alia, para el estudio y/o tratamiento de varias condiciones o enfermedades relacionadas con una vía del complemento.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89239507P | 2007-03-01 | 2007-03-01 | |
| US98502407P | 2007-11-02 | 2007-11-02 | |
| PCT/US2008/055498 WO2008106644A2 (en) | 2007-03-01 | 2008-02-29 | Treatment of diseases characterized by inflammation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009009200A true MX2009009200A (es) | 2009-10-28 |
Family
ID=39721854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009009200A MX2009009200A (es) | 2007-03-01 | 2008-02-29 | Tratamiento de enfermedades caracterizadas por la inflamacion. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20100120665A1 (es) |
| EP (1) | EP2134173A4 (es) |
| JP (1) | JP5332064B2 (es) |
| KR (1) | KR20090122465A (es) |
| AU (2) | AU2008221287A1 (es) |
| CA (1) | CA2678774A1 (es) |
| IL (1) | IL200368A0 (es) |
| MX (1) | MX2009009200A (es) |
| NZ (1) | NZ578873A (es) |
| WO (1) | WO2008106644A2 (es) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007210038B2 (en) | 2006-01-26 | 2013-01-10 | Ionis Pharmaceuticals, Inc. | Compositions and their uses directed to huntingtin |
| JP2011503094A (ja) | 2007-11-08 | 2011-01-27 | ジェネンテック, インコーポレイテッド | 抗b因子抗体およびそれらの使用 |
| US8877896B2 (en) | 2008-02-15 | 2014-11-04 | Tufts University | Compositions, methods and kits for modeling, diagnosing, and treating complement disorders |
| WO2012016162A2 (en) * | 2010-07-29 | 2012-02-02 | Tufts University | Compositions, methods and kits for modeling, diagnosing, and treating complement disorders |
| US8324182B2 (en) * | 2008-02-15 | 2012-12-04 | Tufts University | Humanized model of membrane attack complex (MAC) formation on murine retina and compositions, kits and methods for treatment of macular degeneration |
| EP3192874B1 (en) * | 2008-06-18 | 2019-10-16 | Oxford BioMedica (UK) Limited | Virus purification |
| EP2894166A1 (en) | 2008-11-10 | 2015-07-15 | Alexion Pharmaceuticals, Inc. | Methods and compositions for treating complement-associated disorders |
| US8778999B2 (en) | 2009-03-05 | 2014-07-15 | Insite Vision Incorporated | Non-steroidal anti-inflammatory ophthalmic compositions |
| US11512326B2 (en) | 2009-05-26 | 2022-11-29 | University Of Florida Research Foundation, Incorporated | Small angiotensin peptide expression system in mammalian cells |
| CN104894129B (zh) | 2009-09-11 | 2020-07-10 | Ionis制药公司 | 亨廷顿表达的调节 |
| FR2952639B1 (fr) | 2009-11-16 | 2013-08-30 | Lab Francais Du Fractionnement | Procede de purification de facteur b |
| JP5337096B2 (ja) | 2010-04-28 | 2013-11-06 | 株式会社日立製作所 | 動脈硬化の評価法 |
| CA2843684A1 (en) * | 2010-08-13 | 2012-02-16 | Tufts University | Compositions, kits and methods for treatment of macular degeneration using soluble membrane-independent cd59 protein |
| US9244073B2 (en) | 2011-02-25 | 2016-01-26 | Wellstat Diagnostics, Llc | Assays for detecting enzymatic activity |
| KR101949293B1 (ko) | 2011-05-05 | 2019-02-18 | 웰스태트 이뮤노테라퓨틱스, 엘엘씨 | 보체 인자 b 유사체 및 그의 용도 |
| AU2012272706B2 (en) * | 2011-06-22 | 2017-07-06 | Apellis Pharmaceuticals, Inc. | Methods of treating chronic disorders with complement inhibitors |
| CN110777124A (zh) | 2011-10-27 | 2020-02-11 | 威尔斯达眼科制剂公司 | 编码视杆细胞来源的视锥细胞活力因子的载体 |
| US20130165419A1 (en) * | 2011-12-21 | 2013-06-27 | Insite Vision Incorporated | Combination anti-inflammatory ophthalmic compositions |
| CN103316356B (zh) * | 2012-03-22 | 2016-08-17 | 北京三诺佳邑生物技术有限责任公司 | 一种重组慢病毒载体制剂 |
| WO2013148155A1 (en) * | 2012-03-26 | 2013-10-03 | Digna Biotech Usa, Llc | Compositions and methods for the treatment of dry eye disease |
| US9056874B2 (en) | 2012-05-04 | 2015-06-16 | Novartis Ag | Complement pathway modulators and uses thereof |
| WO2014035876A1 (en) * | 2012-08-27 | 2014-03-06 | William Marsh Rice University | Heat-inactivated complement factor b compositions and methods |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| WO2014164703A1 (en) | 2013-03-11 | 2014-10-09 | University Of Florida Research Foundation, Inc. | Delivery of card protein as therapy for occular inflammation |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| JP6387391B2 (ja) | 2013-03-14 | 2018-09-05 | ノバルティス アーゲー | 眼科疾患の処置に有用な補体因子B阻害剤としての2−(1H−インドール−4−イルメチル)−3H−イミダゾ[4,5−b]ピリジン−6−カルボニトリル誘導体 |
| EA034575B1 (ru) * | 2013-04-18 | 2020-02-21 | Фондацьоне Телетон | Эффективная доставка больших генов посредством двойных aav векторов |
| SG10201906382QA (en) | 2013-05-01 | 2019-08-27 | Ionis Pharmaceuticals Inc | Compositions and methods for modulating hbv and ttr expression |
| EP3011345B1 (en) | 2013-08-07 | 2017-10-04 | Alexion Pharmaceuticals, Inc. | Atypical hemolytic uremic syndrome (ahus) biomarker proteins |
| PE20160500A1 (es) * | 2013-09-13 | 2016-05-21 | Ionis Pharmaceuticals Inc | Moduladores del factor del complemento b |
| JP2016535042A (ja) | 2013-10-30 | 2016-11-10 | ノバルティス アーゲー | 2−ベンジル−ベンゾイミダゾール補体因子b阻害剤およびその使用 |
| US11053291B2 (en) | 2014-02-19 | 2021-07-06 | University Of Florida Research Foundation, Incorporated | Delivery of Nrf2 as therapy for protection against reactive oxygen species |
| WO2015138628A1 (en) * | 2014-03-11 | 2015-09-17 | University Of Florida Research Foundation, Inc. | Use of aav-expressed m013 protein as an anti-inflammatory therapeutic |
| US10155983B2 (en) | 2014-03-31 | 2018-12-18 | Machaon Diagnostics, Inc. | Method of diagnosis of complement-mediated thrombotic microangiopathies |
| SG10201809953QA (en) | 2014-05-01 | 2018-12-28 | Ionis Pharmaceuticals Inc | Compositions and methods for modulating complement factor b expression |
| US12396889B2 (en) | 2014-05-12 | 2025-08-26 | Gholam A. Peyman | Lamellar corneal autologous or homologous graft in refractive surgery |
| US11666777B2 (en) * | 2014-05-12 | 2023-06-06 | Gholam A. Peyman | Photodynamic therapy technique for preventing damage to the fovea of the eye or another body portion of a patient |
| DE102014107380A1 (de) | 2014-05-26 | 2015-11-26 | Eberhard Karls Universität Tübingen Medizinische Fakultät | Verfahren zur Diagnose einer durch den alternativen Weg des Komplementsystems vermittelten Krankheit oder eines Risikos hierfür |
| GB201519086D0 (en) * | 2015-10-28 | 2015-12-09 | Syncona Partners Llp | Gene Therapy |
| WO2017202776A1 (en) * | 2016-05-23 | 2017-11-30 | Luxembourg Institute Of Health (Lih) | Multifunctional heteromultimeric constructs. |
| WO2018005552A1 (en) | 2016-06-27 | 2018-01-04 | Achillion Pharmaceuticals, Inc. | Quinazoline and indole compounds to treat medical disorders |
| CN121343934A (zh) * | 2017-05-10 | 2026-01-16 | 制药五有限责任公司 | 对补体灭活作用具有抗性的用于治疗癌症的包膜病毒 |
| WO2019173283A1 (en) | 2018-03-05 | 2019-09-12 | Marquette University | Method and apparatus for non-invasive hemoglobin level prediction |
| US20210393802A1 (en) * | 2018-11-14 | 2021-12-23 | Regenxbio Inc. | Gene therapy for neuronal ceroid lipofuscinoses |
| US11707505B2 (en) * | 2019-11-15 | 2023-07-25 | King Faisal Specialist Hospital & Research Centre | VCP and factor H as viral entry inhibitors |
| WO2021202836A1 (en) * | 2020-04-01 | 2021-10-07 | The Trustees Of The University Of Pennsylvania | Factor b inhibitors and uses thereof |
| BR112022026127A2 (pt) * | 2020-06-24 | 2023-01-17 | Bioverativ Therapeutics Inc | Métodos para remoção de fator viii livre de preparações de vetores lentivirais modificados para expressar referida proteína |
| JP7766325B2 (ja) * | 2021-10-13 | 2025-11-10 | 学校法人慈恵大学 | レンチウイルスベクター、細胞及び細胞製剤 |
| WO2023230171A2 (en) * | 2022-05-24 | 2023-11-30 | University Of Pittsburgh - Of Thecommonwealth System Of Highereducation | Compositions and methods of treating corneal scarring |
| EP4584255A1 (en) | 2022-09-10 | 2025-07-16 | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. | 2-substituted piperidine derivatives, preparation methods and medicinal uses thereof |
| WO2024206928A1 (en) | 2023-03-30 | 2024-10-03 | Pharma Cinq, Llc | VECTOR ENCODING ROD-DERIVED CONE VIABILITY FACTOR AND HUMAN IgK SIGNAL SEQUENCE |
| AU2024261191A1 (en) | 2023-04-27 | 2025-11-06 | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. | Salt of piperidylindole compound and preparation method therefor |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5679546A (en) * | 1993-09-24 | 1997-10-21 | Cytomed, Inc. | Chimeric proteins which block complement activation |
| US5869615A (en) * | 1994-01-03 | 1999-02-09 | Washington University | Modified complement proteases |
| US6956107B2 (en) * | 1998-02-20 | 2005-10-18 | Tanox, Inc. | Inhibitors of complement activation |
| ES2316446T3 (es) * | 2000-04-29 | 2009-04-16 | University Of Iowa Research Foundation | Diagnostico y terapeutica para trastornos relacionados con la degeneracion macular. |
| PT1713503E (pt) * | 2004-02-10 | 2013-11-14 | Nat Jewish Health | Inibição do factor b, a via alternativa do complemento e métodos relacionados |
| US20060178348A1 (en) * | 2005-01-24 | 2006-08-10 | Pozen Inc. | Compositions and therapeutic methods utilizing a combination of a protein extravasation inhibitor and an NSAID |
| US20070037183A1 (en) * | 2005-03-07 | 2007-02-15 | Trustees Of Boston University | Diagnostic and therapeutic target for macular degeneration |
| AU2006304804B2 (en) * | 2005-10-21 | 2011-06-02 | Vertex Pharmaceuticals Incorporated | Modified proteases that inhibit complement activation |
-
2008
- 2008-02-29 KR KR1020097020557A patent/KR20090122465A/ko not_active Ceased
- 2008-02-29 AU AU2008221287A patent/AU2008221287A1/en not_active Abandoned
- 2008-02-29 MX MX2009009200A patent/MX2009009200A/es not_active Application Discontinuation
- 2008-02-29 EP EP08731123A patent/EP2134173A4/en not_active Withdrawn
- 2008-02-29 JP JP2009551874A patent/JP5332064B2/ja not_active Expired - Fee Related
- 2008-02-29 NZ NZ578873A patent/NZ578873A/en not_active IP Right Cessation
- 2008-02-29 US US12/529,177 patent/US20100120665A1/en not_active Abandoned
- 2008-02-29 CA CA002678774A patent/CA2678774A1/en not_active Abandoned
- 2008-02-29 WO PCT/US2008/055498 patent/WO2008106644A2/en not_active Ceased
-
2009
- 2009-08-12 IL IL200368A patent/IL200368A0/en unknown
-
2014
- 2014-06-23 AU AU2014203398A patent/AU2014203398A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP5332064B2 (ja) | 2013-11-06 |
| WO2008106644A3 (en) | 2008-11-20 |
| EP2134173A2 (en) | 2009-12-23 |
| JP2010520224A (ja) | 2010-06-10 |
| AU2014203398A1 (en) | 2014-07-10 |
| NZ578873A (en) | 2012-01-12 |
| WO2008106644A2 (en) | 2008-09-04 |
| EP2134173A4 (en) | 2010-11-10 |
| IL200368A0 (en) | 2010-04-29 |
| AU2008221287A1 (en) | 2008-09-04 |
| US20100120665A1 (en) | 2010-05-13 |
| CA2678774A1 (en) | 2008-09-04 |
| KR20090122465A (ko) | 2009-11-30 |
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