MX2009008707A - Procedimiento para preparar fenilhidracinas sustituidas. - Google Patents
Procedimiento para preparar fenilhidracinas sustituidas.Info
- Publication number
- MX2009008707A MX2009008707A MX2009008707A MX2009008707A MX2009008707A MX 2009008707 A MX2009008707 A MX 2009008707A MX 2009008707 A MX2009008707 A MX 2009008707A MX 2009008707 A MX2009008707 A MX 2009008707A MX 2009008707 A MX2009008707 A MX 2009008707A
- Authority
- MX
- Mexico
- Prior art keywords
- hydrazine
- preparing substituted
- substituted phenylhydrazines
- formula
- phenylhydrazines
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000004031 phenylhydrazines Chemical class 0.000 title abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 6
- NWZSZGALRFJKBT-KNIFDHDWSA-N (2s)-2,6-diaminohexanoic acid;(2s)-2-hydroxybutanedioic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O.NCCCC[C@H](N)C(O)=O NWZSZGALRFJKBT-KNIFDHDWSA-N 0.000 abstract 1
- NPXCSDPOOVOVDQ-UHFFFAOYSA-N 1,2-dichloro-3-fluorobenzene Chemical compound FC1=CC=CC(Cl)=C1Cl NPXCSDPOOVOVDQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C241/02—Preparation of hydrazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/10—Hydrazines
- C07C243/22—Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Un procedimiento para preparar fenilhidracinas sustituidas de la fórmula I (ver fórmula I) en la que R tiene el significado indicado en la descripción, el cual comprende el paso de hacer reaccionar un diclorofluorobenceno de la fórmula II (ver fórmula II) con una fuente de hidracina seleccionada de entre hidracina, hidrato de hidracina y sales de hidracina por adición de ácido, y que opcionalmente se lleva a cabo en presencia de al menos un disolvente orgánico.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07104341 | 2007-03-16 | ||
| PCT/EP2008/052346 WO2008113661A2 (en) | 2007-03-16 | 2008-02-27 | Process for preparing substituted phenylhydrazines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009008707A true MX2009008707A (es) | 2009-08-24 |
Family
ID=38176774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009008707A MX2009008707A (es) | 2007-03-16 | 2008-02-27 | Procedimiento para preparar fenilhidracinas sustituidas. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100010263A1 (es) |
| EP (1) | EP2137136A2 (es) |
| JP (1) | JP2010521433A (es) |
| KR (1) | KR20090127349A (es) |
| CN (1) | CN101631766A (es) |
| AR (1) | AR068968A1 (es) |
| AU (1) | AU2008228423A1 (es) |
| BR (1) | BRPI0808555A2 (es) |
| CA (1) | CA2679858A1 (es) |
| EA (1) | EA200901174A1 (es) |
| IL (1) | IL200389A0 (es) |
| MX (1) | MX2009008707A (es) |
| WO (1) | WO2008113661A2 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5540067B2 (ja) | 2009-03-16 | 2014-07-02 | ビーエーエスエフ ソシエタス・ヨーロピア | ピラゾール誘導体の調製方法 |
| CN111380975A (zh) * | 2018-12-30 | 2020-07-07 | 江苏万邦生化医药集团有限责任公司 | 马来酸阿法替尼中间体ⅱ中水合肼的检测分析方法 |
| CN117720432A (zh) * | 2022-11-08 | 2024-03-19 | 启东亚太药业有限公司 | 一种芳基肼类化合物的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4388472A (en) * | 1979-07-18 | 1983-06-14 | Imperial Chemical Industries Plc | Substituted diphenyl ethers |
| US4590315A (en) * | 1984-10-15 | 1986-05-20 | Occidental Chemical Corporation | Process for the preparation of halo aromatic compounds |
| DE3447211A1 (de) * | 1984-12-22 | 1986-06-26 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von substituierten phenylhydrazinen |
| DE3725661A1 (de) * | 1987-08-03 | 1989-02-23 | Bayer Ag | 1-arylpyrazole |
-
2008
- 2008-02-27 MX MX2009008707A patent/MX2009008707A/es not_active Application Discontinuation
- 2008-02-27 KR KR1020097021493A patent/KR20090127349A/ko not_active Withdrawn
- 2008-02-27 BR BRPI0808555-2A patent/BRPI0808555A2/pt not_active Application Discontinuation
- 2008-02-27 CA CA002679858A patent/CA2679858A1/en not_active Abandoned
- 2008-02-27 US US12/529,066 patent/US20100010263A1/en not_active Abandoned
- 2008-02-27 EA EA200901174A patent/EA200901174A1/ru unknown
- 2008-02-27 AU AU2008228423A patent/AU2008228423A1/en not_active Abandoned
- 2008-02-27 JP JP2009553101A patent/JP2010521433A/ja not_active Withdrawn
- 2008-02-27 CN CN200880008440A patent/CN101631766A/zh active Pending
- 2008-02-27 WO PCT/EP2008/052346 patent/WO2008113661A2/en not_active Ceased
- 2008-02-27 EP EP08717156A patent/EP2137136A2/en not_active Withdrawn
- 2008-03-14 AR ARP080101088A patent/AR068968A1/es not_active Application Discontinuation
-
2009
- 2009-08-13 IL IL200389A patent/IL200389A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008113661A2 (en) | 2008-09-25 |
| AU2008228423A1 (en) | 2008-09-25 |
| CN101631766A (zh) | 2010-01-20 |
| WO2008113661A3 (en) | 2008-12-04 |
| US20100010263A1 (en) | 2010-01-14 |
| JP2010521433A (ja) | 2010-06-24 |
| EA200901174A1 (ru) | 2010-04-30 |
| IL200389A0 (en) | 2010-04-29 |
| KR20090127349A (ko) | 2009-12-10 |
| EP2137136A2 (en) | 2009-12-30 |
| AR068968A1 (es) | 2009-12-23 |
| CA2679858A1 (en) | 2008-09-25 |
| BRPI0808555A2 (pt) | 2014-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |