[go: up one dir, main page]

MX2009008495A - Novedosos analogos de nucleosidos para el tratamiento de infecciones virales. - Google Patents

Novedosos analogos de nucleosidos para el tratamiento de infecciones virales.

Info

Publication number
MX2009008495A
MX2009008495A MX2009008495A MX2009008495A MX2009008495A MX 2009008495 A MX2009008495 A MX 2009008495A MX 2009008495 A MX2009008495 A MX 2009008495A MX 2009008495 A MX2009008495 A MX 2009008495A MX 2009008495 A MX2009008495 A MX 2009008495A
Authority
MX
Mexico
Prior art keywords
treatment
viral infections
nucleoside analogs
novel nucleoside
novel
Prior art date
Application number
MX2009008495A
Other languages
English (en)
Inventor
Jeyaraj Duraiswamy
Zheng Yin
Yen Liang Chen
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39462074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009008495(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2009008495A publication Critical patent/MX2009008495A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Esta invención se refiere a novedosos compuestos de nucleósido de la fórmula (I) que tienen diferentes aplicaciones medicinales, por ejemplo, para el tratamiento y/o la prevención de infecciones virales. (ver fórmula (I)).
MX2009008495A 2007-02-09 2008-02-07 Novedosos analogos de nucleosidos para el tratamiento de infecciones virales. MX2009008495A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07102027 2007-02-09
EP08150003 2008-01-02
PCT/EP2008/051527 WO2008095993A1 (en) 2007-02-09 2008-02-07 Novel nucleoside analogs for treatment of viral infections

Publications (1)

Publication Number Publication Date
MX2009008495A true MX2009008495A (es) 2009-08-20

Family

ID=39462074

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009008495A MX2009008495A (es) 2007-02-09 2008-02-07 Novedosos analogos de nucleosidos para el tratamiento de infecciones virales.

Country Status (18)

Country Link
US (1) US8278282B2 (es)
EP (1) EP2132216B1 (es)
JP (1) JP2010518047A (es)
KR (1) KR20090109102A (es)
CN (1) CN101600726B (es)
AR (1) AR065249A1 (es)
AT (1) ATE533774T1 (es)
AU (1) AU2008212752A1 (es)
BR (1) BRPI0807222A2 (es)
CA (1) CA2675462A1 (es)
CL (1) CL2008000409A1 (es)
EA (1) EA200901080A1 (es)
ES (1) ES2381093T3 (es)
MX (1) MX2009008495A (es)
PE (1) PE20090070A1 (es)
PT (1) PT2132216E (es)
TW (1) TW200838550A (es)
WO (1) WO2008095993A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR072906A1 (es) * 2008-08-06 2010-09-29 Novartis Ag Nucleosidos modificados utiles como antivirales
CN102526087B (zh) * 2010-12-30 2014-09-03 南开大学 核苷类化合物在制备治疗肠病毒71(ev71)感染疾病药物的应用
CN105669783B (zh) * 2014-12-03 2019-11-12 广东东阳光药业有限公司 一种制备呋喃糖的方法
MX2018001073A (es) 2015-08-06 2018-06-12 Chimerix Inc Nucleosidos de pirrolopirimidina y analogos de los mismos utiles como agentes antivirales.
EP3352781B1 (en) 2015-09-23 2020-12-16 Merck Sharp & Dohme Corp. 4'-substituted nucleoside reverse transcriptase inhibitors and preparations thereof
JP7129703B2 (ja) * 2016-04-28 2022-09-02 エモリー ユニバーシティー アルキン含有ヌクレオチド及びヌクレオシド治療組成物並びにそれらに関連した使用
TW201815821A (zh) * 2016-07-18 2018-05-01 美商再生元醫藥公司 抗茲卡病毒抗體及使用方法
JP2019524795A (ja) * 2016-08-12 2019-09-05 ヤンセン バイオファーマ インク． 置換ヌクレオシド、ヌクレオチド、及びそのアナログ
EP3684771B1 (en) 2017-09-21 2024-11-27 Chimerix, Inc. Morphic forms of 4-amino-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methyl-7h-pyrrolo(2,3-d)pyrimidine-5-carboxamide and uses thereof
WO2020219447A1 (en) 2019-04-23 2020-10-29 Elementis Specialties, Inc. Slurry compositions containing mixed branched alkyl organoclay compositions
EP4454650A4 (en) * 2021-12-22 2025-10-22 Cj Cheiljedang Corp ANTIVIRAL COMPOSITION COMPRISING NUCLEOSIDE ANALOGUES DERIVED FROM A NUCLEIC ACID AND A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
WO2024012568A1 (en) * 2022-07-15 2024-01-18 Sunshine Lake Pharma Co., Ltd. A key intermediate for preparing glucopyranosyl derivatives and preparation method thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1355916T1 (sl) * 2001-01-22 2007-04-30 Merck & Co Inc Nukleozidni derivati kot inhibitorji RNA-odvisne RNA virusne polimeraze
WO2003051352A1 (en) 2001-12-14 2003-06-26 Alcon, Inc. Aminoalkyl-benzofuran-5-ol compounds for the treatment of glaucoma
JP2005527499A (ja) * 2002-02-13 2005-09-15 メルク　エンド　カムパニー　インコーポレーテッド ヌクレオシド化合物を用いてオルトポックスウイルスの複製を阻害する方法
CN1653077A (zh) 2002-05-06 2005-08-10 健亚生物科技公司 治疗c型肝炎病毒感染的核苷衍生物
EP1572097A4 (en) * 2002-09-30 2010-02-17 Smithkline Beecham Corp NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF INFECTIONS WITH THE HEPATITIS C-VIRUS
US20040259934A1 (en) * 2003-05-01 2004-12-23 Olsen David B. Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds
MXPA06004680A (es) * 2003-10-27 2007-04-17 Genelabs Tech Inc Compuestos de nucleosido para el tratamiento de infecciones virales.

Also Published As

Publication number Publication date
ATE533774T1 (de) 2011-12-15
EP2132216A1 (en) 2009-12-16
EP2132216B1 (en) 2011-11-16
ES2381093T3 (es) 2012-05-23
WO2008095993A1 (en) 2008-08-14
BRPI0807222A2 (pt) 2014-04-29
EA200901080A1 (ru) 2010-02-26
US8278282B2 (en) 2012-10-02
JP2010518047A (ja) 2010-05-27
KR20090109102A (ko) 2009-10-19
US20100227833A1 (en) 2010-09-09
PE20090070A1 (es) 2009-03-19
AU2008212752A1 (en) 2008-08-14
CN101600726A (zh) 2009-12-09
CN101600726B (zh) 2013-03-27
PT2132216E (pt) 2012-02-20
AR065249A1 (es) 2009-05-27
CA2675462A1 (en) 2008-08-14
TW200838550A (en) 2008-10-01
CL2008000409A1 (es) 2008-08-29

Similar Documents

Publication Publication Date Title
MX2009008495A (es) Novedosos analogos de nucleosidos para el tratamiento de infecciones virales.
GEP201706793B (en) Substituted nucleosides, nucleotides and analogs thereof
PH12012502284A1 (en) Antiviral nucleoside analogs
MX2009013830A (es) Compuestos antivirales.
MX2009013827A (es) Compuestos antivirales.
MX2009011533A (es) Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.
GEP20135964B (en) Inhibitors of beta-secretase
WO2009026179A3 (en) Antiinfective proanthocyanidin compounds and methods of use thereof
WO2008127364A3 (en) Antiviral compounds and use thereof
MX2010005136A (es) Prevencion y tratamiento de infecciones secundarias tras una infeccion viral.
IN2012DN00869A (es)
GEP20156313B (en) Substituted nucleotide analogs
MA33803B1 (fr) Inhibiteur de bromodomaine de benzodiazépine
TW200738742A (en) Antiviral compounds
MX2012002031A (es) Moleculas pequeñas que contienen boro como agentes antiprotozoarios.
UA94749C2 (en) Benzimidazole modulators of vr1
WO2010029302A3 (en) Compounds for treating viral infections
PH12015502588A1 (en) 4`-fluoro-2`-methyl substituted nucleoside derivatives
MX2015011193A (es) Compuestos antivirales.
CA3010327A1 (en) Aryl substituted pyrimidines for use in influenza virus infection
ZA202001780B (en) Bezimidazole derivatives as adenosine receptor antagonists
WO2007120374A3 (en) Anti-arenaviral compounds
MX2016001855A (es) Nuevos aza-oxo-indoles para el tratamiento y profilaxis de la infeccion por virus sincitial respiratorio.
IN2014CN00572A (es)
MA32841B1 (fr) Composés de cycloundeca depsipeptides et leur utilisation comme médicament

Legal Events

Date Code Title Description
HH Correction or change in general
FG Grant or registration