MX2009006074A - Uso de epotilonas en el tratamiento de la osteoporosis y enfermedades relacionadas. - Google Patents
Uso de epotilonas en el tratamiento de la osteoporosis y enfermedades relacionadas.Info
- Publication number
- MX2009006074A MX2009006074A MX2009006074A MX2009006074A MX2009006074A MX 2009006074 A MX2009006074 A MX 2009006074A MX 2009006074 A MX2009006074 A MX 2009006074A MX 2009006074 A MX2009006074 A MX 2009006074A MX 2009006074 A MX2009006074 A MX 2009006074A
- Authority
- MX
- Mexico
- Prior art keywords
- epothilones
- osteoporosis
- treatment
- related diseases
- dysbalance
- Prior art date
Links
- 208000001132 Osteoporosis Diseases 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 229930013356 epothilone Natural products 0.000 title abstract 2
- HESCAJZNRMSMJG-KKQRBIROSA-N epothilone A Chemical class C/C([C@@H]1C[C@@H]2O[C@@H]2CCC[C@@H]([C@@H]([C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O1)O)C)=C\C1=CSC(C)=N1 HESCAJZNRMSMJG-KKQRBIROSA-N 0.000 title abstract 2
- 210000000963 osteoblast Anatomy 0.000 abstract 1
- 210000002997 osteoclast Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención se relaciona con el uso de epotilonas naturales o sintéticas para el tratamiento, la prevención o la mitigación de enfermedades causadas por el desequilibrio de la actividad y osteoblástica, especialmente las osteoporosis.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06025424A EP1930004A1 (en) | 2006-12-08 | 2006-12-08 | Use of epothilones in the treatment of osteoporosis and related diseases |
| PCT/EP2007/010789 WO2008068043A1 (en) | 2006-12-08 | 2007-12-05 | Use of epothilones in the treatment of osteoporosis and related diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009006074A true MX2009006074A (es) | 2009-08-24 |
Family
ID=38008136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009006074A MX2009006074A (es) | 2006-12-08 | 2007-12-05 | Uso de epotilonas en el tratamiento de la osteoporosis y enfermedades relacionadas. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20080146626A1 (es) |
| EP (2) | EP1930004A1 (es) |
| KR (1) | KR20090087038A (es) |
| CN (1) | CN101553227A (es) |
| AR (1) | AR064214A1 (es) |
| AU (1) | AU2007327767A1 (es) |
| BR (1) | BRPI0719997A2 (es) |
| CA (1) | CA2672114A1 (es) |
| CL (1) | CL2007003553A1 (es) |
| IL (1) | IL198493A0 (es) |
| MX (1) | MX2009006074A (es) |
| TW (1) | TW200829239A (es) |
| UY (1) | UY30769A1 (es) |
| WO (1) | WO2008068043A1 (es) |
| ZA (1) | ZA200904755B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110300150A1 (en) | 2010-05-18 | 2011-12-08 | Scott Eliasof | Compositions and methods for treatment of autoimmune and other disease |
| RU2496511C1 (ru) * | 2012-04-20 | 2013-10-27 | Замертон Холдингс Лимитед | Фармацевтическая композиция, средство (варианты) и способ профилактики и лечения артрита, остеоартроза и остеохондроза позвоночника (варианты) |
| CN108430996A (zh) * | 2015-10-16 | 2018-08-21 | 威廉马歇莱思大学 | 埃博霉素类似物、合成方法、治疗方法及其药物缀合物 |
| CN110974824A (zh) * | 2019-12-18 | 2020-04-10 | 中国人民解放军陆军军医大学第一附属医院 | 埃博霉素b在制备防治炎症性骨丢失药物中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6320045B1 (en) * | 1997-12-04 | 2001-11-20 | Bristol-Myers Squibb Company | Process for the reduction of oxiranyl epothilones to olefinic epothilones |
| US6893859B2 (en) * | 2001-02-13 | 2005-05-17 | Kosan Biosciences, Inc. | Epothilone derivatives and methods for making and using the same |
| AU2002338336A1 (en) * | 2001-04-03 | 2002-10-21 | Kosan Biosciences, Inc. | Epothilone derivatives and methods for making and using the same |
| US20060069136A1 (en) * | 2004-09-24 | 2006-03-30 | Ulrich Klar | Use of Epothilones in the treatment of bone metastasis |
| EP1640004A1 (en) * | 2004-09-24 | 2006-03-29 | Schering Aktiengesellschaft | Use of epothilones in the treatment of bone metastases and bone tumors or cancers |
-
2006
- 2006-12-08 EP EP06025424A patent/EP1930004A1/en not_active Withdrawn
-
2007
- 2007-12-05 WO PCT/EP2007/010789 patent/WO2008068043A1/en not_active Ceased
- 2007-12-05 AU AU2007327767A patent/AU2007327767A1/en not_active Abandoned
- 2007-12-05 BR BRPI0719997-0A2A patent/BRPI0719997A2/pt not_active Application Discontinuation
- 2007-12-05 CN CNA200780045413XA patent/CN101553227A/zh active Pending
- 2007-12-05 MX MX2009006074A patent/MX2009006074A/es not_active Application Discontinuation
- 2007-12-05 EP EP07856543A patent/EP2101765A1/en not_active Withdrawn
- 2007-12-05 CA CA002672114A patent/CA2672114A1/en not_active Abandoned
- 2007-12-05 KR KR1020097011604A patent/KR20090087038A/ko not_active Withdrawn
- 2007-12-07 CL CL200703553A patent/CL2007003553A1/es unknown
- 2007-12-07 TW TW096146830A patent/TW200829239A/zh unknown
- 2007-12-07 UY UY30769A patent/UY30769A1/es not_active Application Discontinuation
- 2007-12-10 AR ARP070105516A patent/AR064214A1/es unknown
-
2008
- 2008-02-27 US US11/952,666 patent/US20080146626A1/en not_active Abandoned
-
2009
- 2009-04-30 IL IL198493A patent/IL198493A0/en unknown
- 2009-07-07 ZA ZA200904755A patent/ZA200904755B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200904755B (en) | 2010-09-29 |
| EP2101765A1 (en) | 2009-09-23 |
| AR064214A1 (es) | 2009-03-18 |
| CL2007003553A1 (es) | 2008-07-04 |
| IL198493A0 (en) | 2010-02-17 |
| BRPI0719997A2 (pt) | 2014-03-18 |
| CN101553227A (zh) | 2009-10-07 |
| UY30769A1 (es) | 2008-07-31 |
| EP1930004A1 (en) | 2008-06-11 |
| CA2672114A1 (en) | 2008-06-12 |
| KR20090087038A (ko) | 2009-08-14 |
| AU2007327767A1 (en) | 2008-06-12 |
| WO2008068043A1 (en) | 2008-06-12 |
| US20080146626A1 (en) | 2008-06-19 |
| TW200829239A (en) | 2008-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |