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MX2009004561A - Derivados de pirazolilo con actividad analgesica y utiles en el tratamiento o profilaxis del dolor. - Google Patents

Derivados de pirazolilo con actividad analgesica y utiles en el tratamiento o profilaxis del dolor.

Info

Publication number
MX2009004561A
MX2009004561A MX2009004561A MX2009004561A MX2009004561A MX 2009004561 A MX2009004561 A MX 2009004561A MX 2009004561 A MX2009004561 A MX 2009004561A MX 2009004561 A MX2009004561 A MX 2009004561A MX 2009004561 A MX2009004561 A MX 2009004561A
Authority
MX
Mexico
Prior art keywords
treatment
pain
prophylaxis
analgesic activity
useful
Prior art date
Application number
MX2009004561A
Other languages
English (en)
Inventor
Alf Claesson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2009004561A publication Critical patent/MX2009004561A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Esta invención se relaciona con el uso novedoso de derivados de pirazolilo y sales farmacéuticamente aceptables de estas, las cuales se ha encontrado que poseen actividad analgésica y por consiguiente son útiles en el tratamiento o profilaxis de padecimientos de dolor en el cuerpo humano o animal, por ejemplo, en la elaboración de medicamentos para el tratamiento o prevención en un animal de sangre caliente como el hombre.
MX2009004561A 2006-11-01 2007-10-31 Derivados de pirazolilo con actividad analgesica y utiles en el tratamiento o profilaxis del dolor. MX2009004561A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86383906P 2006-11-01 2006-11-01
PCT/SE2007/000966 WO2008054291A1 (en) 2006-11-01 2007-10-31 Pyrazolyl derivatives with analgesic activity and therefore useful in the treatment or prophylaxis of pain.

Publications (1)

Publication Number Publication Date
MX2009004561A true MX2009004561A (es) 2009-05-11

Family

ID=39344535

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009004561A MX2009004561A (es) 2006-11-01 2007-10-31 Derivados de pirazolilo con actividad analgesica y utiles en el tratamiento o profilaxis del dolor.

Country Status (12)

Country Link
US (1) US20080108633A1 (es)
EP (1) EP2091540A4 (es)
JP (1) JP2010508345A (es)
KR (1) KR20090077063A (es)
CN (1) CN101534830A (es)
AU (1) AU2007314657A1 (es)
BR (1) BRPI0718003A2 (es)
CA (1) CA2668321A1 (es)
MX (1) MX2009004561A (es)
RU (1) RU2009112013A (es)
TW (1) TW200823196A (es)
WO (1) WO2008054291A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0104140D0 (sv) * 2001-12-07 2001-12-07 Astrazeneca Ab Novel Compounds
SI1846394T1 (sl) 2005-02-04 2012-06-29 Astrazeneca Ab Pirazolilaminopiridinski derivati uporabni kot kinazni inhibitorji
BRPI0607455A2 (pt) * 2005-02-16 2009-09-01 Astrazeneca Ab composto, processo para a preparação do mesmo, uso de um composto, e composição farmacêutica
JP2008540622A (ja) * 2005-05-16 2008-11-20 アストラゼネカ アクチボラグ 化合物
EP1945631B8 (en) * 2005-10-28 2013-01-02 AstraZeneca AB 4- (3-aminopyrazole) pyrimidine derivatives for use as tyrosine kinase inhibitors in the treatment of cancer
WO2008129255A1 (en) * 2007-04-18 2008-10-30 Astrazeneca Ab 5-aminopyrazol-3-yl-3h-imidazo [4,5-b] pyridine derivatives and their use for the treatment of cancer
UA99459C2 (en) * 2007-05-04 2012-08-27 Астразенека Аб 9-(pyrazol-3-yl)- 9h-purine-2-amine and 3-(pyraz0l-3-yl)-3h-imidazo[4,5-b]pyridin-5-amine derivatives and their use for the treatment of cancer
TW201006830A (en) * 2008-06-11 2010-02-16 Astrazeneca Ab Chemical compounds
MX2011003447A (es) * 2008-09-30 2011-07-29 Astrazeneca Ab Inhibidores heterociclicos de jak quinasa.
EP3443959A1 (en) * 2013-12-12 2019-02-20 Bio-Pharm Solutions Co., Ltd. Sulfamate derivative compounds for use in treating or alleviating pain
WO2015088271A1 (en) 2013-12-12 2015-06-18 Bio-Pharm Solutions, Co., Ltd. Sulfamate derivative compound for use in preventing or treating epilepsy
ES2663804T3 (es) * 2013-12-12 2018-04-17 Bio-Pharm Solutions Co., Ltd. Compuestos derivados de sulfamato para su uso en el tratamiento o el alivio del dolor
JP6427039B2 (ja) * 2015-03-04 2018-11-21 株式会社浜松ファーマリサーチ 非ヒト霊長類の二足歩行時の体動痛の評価方法
BR112021019911A2 (pt) * 2019-05-15 2021-12-07 Claes Thulin 4-[5-[(rac)-1-[5-(3-clorofenil)-3-isoxazolil]etoxi]-4-metil-4h-1,2,4-triazol-3-il]piridina para uso na prevenção e/ou no tratamento da dor em um animal
US11987582B2 (en) * 2021-01-27 2024-05-21 Abion Inc. Maleate salts of triazolopyrazine derivatives, compositions, methods of use, and processes of manufacturing the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001288374A1 (en) * 2000-09-01 2002-03-22 Glaxo Group Limited Substituted oxindole derivatives as tyrosine kinase inhibitors
MY141220A (en) * 2003-11-17 2010-03-31 Astrazeneca Ab Pyrazole derivatives as inhibitors of receptor tyrosine kinases
AU2005260031B2 (en) * 2004-06-25 2008-10-09 Amgen Inc. Condensed triazoles and indazoles useful in treating citokines mediated diseases and other diseases
AU2005289426A1 (en) * 2004-09-27 2006-04-06 Amgen Inc. Substituted heterocyclic compounds and methods of use
CN101208093A (zh) * 2005-04-27 2008-06-25 阿斯利康(瑞典)有限公司 吡唑-嘧啶衍生物在治疗疼痛中的用途
JP2008540622A (ja) * 2005-05-16 2008-11-20 アストラゼネカ アクチボラグ 化合物

Also Published As

Publication number Publication date
AU2007314657A1 (en) 2008-05-08
CN101534830A (zh) 2009-09-16
JP2010508345A (ja) 2010-03-18
EP2091540A4 (en) 2010-11-17
WO2008054291A1 (en) 2008-05-08
RU2009112013A (ru) 2010-12-10
BRPI0718003A2 (pt) 2013-11-19
CA2668321A1 (en) 2008-05-08
TW200823196A (en) 2008-06-01
US20080108633A1 (en) 2008-05-08
EP2091540A1 (en) 2009-08-26
KR20090077063A (ko) 2009-07-14

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