BRPI0821689A2 - Processo para a produção de derivados de piridina substituídos por heterociclo - Google Patents
Processo para a produção de derivados de piridina substituídos por heterocicloInfo
- Publication number
- BRPI0821689A2 BRPI0821689A2 BRPI0821689-4A BRPI0821689A BRPI0821689A2 BR PI0821689 A2 BRPI0821689 A2 BR PI0821689A2 BR PI0821689 A BRPI0821689 A BR PI0821689A BR PI0821689 A2 BRPI0821689 A2 BR PI0821689A2
- Authority
- BR
- Brazil
- Prior art keywords
- production
- pyridine derivatives
- substituted pyridine
- heterocycle substituted
- heterocycle
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- C07D213/643—2-Phenoxypyridines; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1679107P | 2007-12-26 | 2007-12-26 | |
| PCT/JP2008/073545 WO2009081970A1 (ja) | 2007-12-26 | 2008-12-25 | ヘテロ環置換ピリジン誘導体の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0821689A2 true BRPI0821689A2 (pt) | 2015-06-16 |
Family
ID=40801269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0821689-4A BRPI0821689A2 (pt) | 2007-12-26 | 2008-12-25 | Processo para a produção de derivados de piridina substituídos por heterociclo |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8410277B2 (pt) |
| EP (1) | EP2226320A4 (pt) |
| JP (1) | JPWO2009081970A1 (pt) |
| CN (1) | CN101910159B (pt) |
| BR (1) | BRPI0821689A2 (pt) |
| CA (1) | CA2709664A1 (pt) |
| IL (1) | IL206391A0 (pt) |
| RU (1) | RU2474581C2 (pt) |
| WO (1) | WO2009081970A1 (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1669348A4 (en) | 2003-09-30 | 2009-03-11 | Eisai R&D Man Co Ltd | NEW ANTIPILIC AGENT CONTAINING A HETEROCYCLIC COMPOUND |
| WO2006106711A1 (ja) | 2005-03-30 | 2006-10-12 | Eisai R & D Management Co., Ltd. | ピリジン誘導体を含有する抗真菌剤 |
| TWI385169B (zh) | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | 經雜環取代之吡啶衍生物及含有彼之抗真菌劑 |
| EP2065377B1 (en) | 2006-09-21 | 2011-11-23 | Eisai R&D Management Co., Ltd. | Pyridine derivative substituted by heteroaryl ring, and antifungal agent comprising the same |
| TW200841879A (en) | 2007-04-27 | 2008-11-01 | Eisai R&D Man Co Ltd | Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same |
| CN102702185A (zh) | 2007-04-27 | 2012-10-03 | 卫材R&D管理有限公司 | 杂环取代吡啶衍生物的盐的结晶 |
| US8513287B2 (en) | 2007-12-27 | 2013-08-20 | Eisai R&D Management Co., Ltd. | Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same |
| WO2010032874A1 (ja) * | 2008-09-19 | 2010-03-25 | 住友化学株式会社 | 農業用組成物 |
| US8188119B2 (en) | 2008-10-24 | 2012-05-29 | Eisai R&D Management Co., Ltd | Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same |
| WO2011051198A2 (de) | 2009-10-30 | 2011-05-05 | Bayer Cropscience Ag | Pyridin-derivate als pflanzenschutzmittel |
| US9234112B2 (en) * | 2013-06-05 | 2016-01-12 | Korea Institute Of Machinery & Materials | Metal precursor powder, method of manufacturing conductive metal layer or pattern, and device including the same |
| JP2016164126A (ja) * | 2013-07-02 | 2016-09-08 | 日本曹達株式会社 | アミノピリジン誘導体および農園芸用殺菌剤 |
| CN109721640B (zh) * | 2017-10-31 | 2025-01-14 | 鲁南制药集团股份有限公司 | 一种卡泊芬净中间体及其合成方法 |
| IL275121B2 (en) | 2017-12-07 | 2025-11-01 | Amplyx Pharmaceuticals Inc | Heterocycle substituted pyridine derivative antifungal agents |
| US11771688B2 (en) | 2018-06-25 | 2023-10-03 | Amplyx Pharmaceuticals, Inc. | Pyridine derivatives substituted by heterocyclic ring and amino group |
| CA3121202A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3844227A1 (de) | 1988-12-29 | 1990-07-05 | Basf Ag | 3(2h)-pyridazinonderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen |
| GB2276161A (en) | 1993-03-17 | 1994-09-21 | Glaxo Group Ltd | Aniline and benzanilide derivatives |
| US5444050A (en) | 1994-04-29 | 1995-08-22 | Texas Biotechnology Corporation | Binding of E-selectin or P-selectin to sialyl Lewisx or sialyl-Lewisa |
| FR2737721B1 (fr) * | 1995-08-08 | 1997-09-05 | Roussel Uclaf | Nouveaux composes biphenyles, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicament et les compositions pharmaceutiques les contenant |
| ES2179490T3 (es) | 1997-05-08 | 2003-01-16 | Merck Sharp & Dohme | Derivados de 1,2,4-triazolo(3,4-a)ftalazina sustituidos como ligandos de gaba alfa 5. |
| DE19917979A1 (de) | 1999-04-21 | 2000-10-26 | Clariant Gmbh | Verfahren zur Herstellung von substituierten Phenyl-boronsäuren |
| NZ541266A (en) | 2000-07-07 | 2006-11-30 | Eisai Co Ltd | DNA encoding proteins participating in fungal cell wall synthesis |
| PL365441A1 (en) | 2001-04-05 | 2005-01-10 | Torrent Pharmaceuticals Ltd. | Heterocyclic compounds for aging-related and diabetic vascular complications |
| JP2005501822A (ja) | 2001-06-27 | 2005-01-20 | メルク フロスト カナダ アンド カンパニー | 置換８−アリールキノリン系ｐｄｅ４阻害薬 |
| JP2006502962A (ja) | 2002-01-18 | 2006-01-26 | ビーエーエスエフ アクチェンゲゼルシャフト | ペルオキシドによる皮膚損傷を防止するための化粧用又は皮膚用製剤 |
| WO2003104227A1 (de) | 2002-01-20 | 2003-12-18 | Bayer Healthcare Ag | 2-heteroarylcarbonsäureamide |
| EP1549632A4 (en) | 2002-05-28 | 2005-11-09 | Dimensional Pharm Inc | NEW THIOPHENAMIDINE, COMPOSITIONS AND METHOD FOR THE TREATMENT OF COMPLEMENTED DISEASES AND SUFFERING |
| US7153968B2 (en) * | 2002-06-25 | 2006-12-26 | Merck Frosst Canada, Ltd. | 8-(biaryl)quinoline PDE4 inhibitors |
| KR20050115337A (ko) | 2003-04-30 | 2005-12-07 | 디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 | 단백질 티로신 포스파타제 ―１ｂ의 억제제로서의 치환된아미노 카르복실산 |
| WO2004100947A2 (en) | 2003-05-06 | 2004-11-25 | Smithkline Beecham Corporation | Novel chemical compounds |
| EP1669348A4 (en) | 2003-09-30 | 2009-03-11 | Eisai R&D Man Co Ltd | NEW ANTIPILIC AGENT CONTAINING A HETEROCYCLIC COMPOUND |
| JP2006248938A (ja) * | 2005-03-09 | 2006-09-21 | Kyowa Hakko Kogyo Co Ltd | 含ホウ素キナゾリン誘導体 |
| US7572808B2 (en) * | 2005-06-17 | 2009-08-11 | Bristol-Myers Squibb Company | Triazolopyridine cannabinoid receptor 1 antagonists |
| CA2626767C (en) | 2005-10-31 | 2012-01-17 | Eisai R&D Management Co., Ltd. | Heterocyclic substituted pyridine derivatives and antifungal agent containing same |
| TWI385169B (zh) | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | 經雜環取代之吡啶衍生物及含有彼之抗真菌劑 |
| RU2380365C1 (ru) * | 2005-10-31 | 2010-01-27 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Гетероциклические замещенные производные пиримидина и содержащий их противогрибковый агент |
| PE20121506A1 (es) | 2006-07-14 | 2012-11-26 | Amgen Inc | Compuestos triazolopiridinas como inhibidores de c-met |
| US9259426B2 (en) * | 2006-07-20 | 2016-02-16 | Gilead Sciences, Inc. | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections |
| EP2049520A4 (en) * | 2006-08-07 | 2011-01-05 | Ironwood Pharmaceuticals Inc | indole compounds |
| WO2008023248A2 (en) | 2006-08-24 | 2008-02-28 | Wockhardt Research Centre | Novel macrolides and ketolides having antimicrobial activity |
| MX2009008531A (es) | 2007-02-16 | 2009-08-26 | Amgen Inc | Cetonas de heterociclilo que contienen nitrogeno y su uso como inhibidores de c-met. |
| CN102702185A (zh) | 2007-04-27 | 2012-10-03 | 卫材R&D管理有限公司 | 杂环取代吡啶衍生物的盐的结晶 |
| US8202873B2 (en) | 2007-05-11 | 2012-06-19 | Eli Lilly And Company | 2-[4-(pyrazol-4-ylalkyl)piperazin-1-yl]-3-phenyl pyrazines as 5-HT7 receptor antagonists |
| US20090197880A1 (en) | 2007-07-13 | 2009-08-06 | Genelabs Technologies, Inc. | Anti-viral compounds, compositions, and methods of use |
| UY31507A1 (es) * | 2007-12-03 | 2009-07-17 | Derivados de piridina activadores de guanilato ciclasa soluble |
-
2008
- 2008-12-25 JP JP2009547127A patent/JPWO2009081970A1/ja active Pending
- 2008-12-25 RU RU2010125902/04A patent/RU2474581C2/ru not_active IP Right Cessation
- 2008-12-25 BR BRPI0821689-4A patent/BRPI0821689A2/pt not_active IP Right Cessation
- 2008-12-25 WO PCT/JP2008/073545 patent/WO2009081970A1/ja not_active Ceased
- 2008-12-25 CN CN2008801230268A patent/CN101910159B/zh not_active Expired - Fee Related
- 2008-12-25 EP EP08863620A patent/EP2226320A4/en not_active Withdrawn
- 2008-12-25 CA CA2709664A patent/CA2709664A1/en not_active Abandoned
- 2008-12-25 US US12/809,011 patent/US8410277B2/en not_active Expired - Fee Related
-
2010
- 2010-06-15 IL IL206391A patent/IL206391A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2009081970A1 (ja) | 2011-05-06 |
| RU2010125902A (ru) | 2012-02-10 |
| WO2009081970A1 (ja) | 2009-07-02 |
| US8410277B2 (en) | 2013-04-02 |
| EP2226320A1 (en) | 2010-09-08 |
| RU2474581C2 (ru) | 2013-02-10 |
| CA2709664A1 (en) | 2009-07-02 |
| EP2226320A4 (en) | 2012-07-11 |
| IL206391A0 (en) | 2010-12-30 |
| US20110263845A1 (en) | 2011-10-27 |
| CN101910159B (zh) | 2013-06-19 |
| CN101910159A (zh) | 2010-12-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |