MX2008009579A - Metodo para el tratamiento de dolor neuropatico. - Google Patents
Metodo para el tratamiento de dolor neuropatico.Info
- Publication number
- MX2008009579A MX2008009579A MX2008009579A MX2008009579A MX2008009579A MX 2008009579 A MX2008009579 A MX 2008009579A MX 2008009579 A MX2008009579 A MX 2008009579A MX 2008009579 A MX2008009579 A MX 2008009579A MX 2008009579 A MX2008009579 A MX 2008009579A
- Authority
- MX
- Mexico
- Prior art keywords
- neuropathic pain
- treatment
- compounds
- slp
- pain
- Prior art date
Links
- 208000004296 neuralgia Diseases 0.000 title abstract 2
- 208000021722 neuropathic pain Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000002193 Pain Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Se proporcionan compuestos y métodos útiles para prevenir y tratar dolor, por ejemplo, en un sujeto que necesita de los mismos. Los compuestos pueden ser agentes de "modulación SIP" que son capaces de inducir un cambio detectable en la actividad del receptor SIP.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76258906P | 2006-01-27 | 2006-01-27 | |
| PCT/US2007/002422 WO2007089715A2 (en) | 2006-01-27 | 2007-01-29 | Method for treatment of neuropathic pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008009579A true MX2008009579A (es) | 2008-09-25 |
Family
ID=38179799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008009579A MX2008009579A (es) | 2006-01-27 | 2007-01-29 | Metodo para el tratamiento de dolor neuropatico. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8008286B2 (es) |
| EP (1) | EP1986623A2 (es) |
| JP (1) | JP2009528274A (es) |
| KR (1) | KR20080086546A (es) |
| CN (1) | CN101378741A (es) |
| AU (1) | AU2007209961A1 (es) |
| BR (1) | BRPI0707281A2 (es) |
| CA (1) | CA2640366A1 (es) |
| IL (1) | IL193040A0 (es) |
| MX (1) | MX2008009579A (es) |
| RU (1) | RU2008134702A (es) |
| WO (1) | WO2007089715A2 (es) |
| ZA (1) | ZA200806349B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1827606A2 (en) | 2004-12-06 | 2007-09-05 | University Of Virginia Patent Foundation | Aryl amide sphingosine 1-phosphate analogs |
| WO2007092638A1 (en) * | 2006-02-09 | 2007-08-16 | University Of Virginia Patent Foundation | Bicyclic sphingosine 1-phosphate analogs |
| AU2007323540A1 (en) | 2006-11-21 | 2008-05-29 | University Of Virginia Patent Foundation | Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity |
| CA2669124A1 (en) * | 2006-11-21 | 2008-05-29 | University Of Virginia Patent Foundation | Benzocycloheptyl analogs having sphingosine 1-phosphate receptor activity |
| JP2010510249A (ja) | 2006-11-21 | 2010-04-02 | ユニバーシティ オブ バージニア パテント ファンデーション | スフィンゴシン=1−燐酸アゴニスト活性を有するテトラリンアナログ |
| WO2008079380A1 (en) | 2006-12-21 | 2008-07-03 | Abbott Laboratories | Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane carboxylates |
| EP2177521A1 (en) | 2008-10-14 | 2010-04-21 | Almirall, S.A. | New 2-Amidothiadiazole Derivatives |
| EP2202232A1 (en) | 2008-12-26 | 2010-06-30 | Laboratorios Almirall, S.A. | 1,2,4-oxadiazole derivatives and their therapeutic use |
| EP2210890A1 (en) | 2009-01-19 | 2010-07-28 | Almirall, S.A. | Oxadiazole derivatives as S1P1 receptor agonists |
| EP2305660A1 (en) | 2009-09-25 | 2011-04-06 | Almirall, S.A. | New thiadiazole derivatives |
| EP2343287A1 (en) | 2009-12-10 | 2011-07-13 | Almirall, S.A. | New 2-aminothiadiazole derivatives |
| EP2366702A1 (en) | 2010-03-18 | 2011-09-21 | Almirall, S.A. | New oxadiazole derivatives |
| EP2390252A1 (en) | 2010-05-19 | 2011-11-30 | Almirall, S.A. | New pyrazole derivatives |
| US9682078B2 (en) * | 2011-03-18 | 2017-06-20 | University Of Virginia Patent Foundation | Compositions and methods for tissue engineering and cell based therapies |
| TWI613182B (zh) | 2013-02-21 | 2018-02-01 | 必治妥美雅史谷比公司 | 雙環化合物 |
| AR101591A1 (es) | 2014-08-20 | 2016-12-28 | Bristol Myers Squibb Co | Compuestos bicíclicos sustituidos |
| KR102805359B1 (ko) * | 2019-11-14 | 2025-05-12 | 삼성전자주식회사 | 비트라인 전압을 제어하는 저항성 메모리 장치 |
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| DE1056139B (de) | 1956-03-31 | 1959-04-30 | Hoechst Ag | Verfahren zur Herstellung von alpha-Amino-beta-oxy-carbonsaeureaniliden |
| US3153092A (en) | 1961-07-17 | 1964-10-13 | Smith Kline French Lab | 1-methyl-2-phenylcyclopropylamine derivatives |
| DE3544373A1 (de) | 1985-12-14 | 1987-06-19 | Hoechst Ag | Verfahren zur herstellung von phosphinothricin-carboxamiden |
| ATE72816T1 (de) * | 1986-11-21 | 1992-03-15 | Ciba Geigy Ag | Neue substituierte alkandiphosphonsaeuren. |
| US5646281A (en) * | 1990-12-28 | 1997-07-08 | Neurogen Corporation | Certain 4-piperidino- and piperazinomethyl-2-phenyl imidazole derivatives; dopamine receptor subtype specific ligands |
| DE4134156A1 (de) * | 1991-10-11 | 1993-04-15 | Schering Ag | 9-substituierte bicyclo(3.3.0)octan-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung |
| JPH06135936A (ja) | 1992-10-24 | 1994-05-17 | Fuji Kagaku Kogyo Kk | 新規なナフタレン誘導体及びその中間体 |
| JPH06135935A (ja) | 1992-10-24 | 1994-05-17 | Fuji Kagaku Kogyo Kk | 新規なナフタレン誘導体およびその中間体 |
| AU1865499A (en) * | 1997-12-30 | 1999-07-26 | Allelix Biopharmaceuticals Inc. | Identification of lysolipid receptors involved in inflammatory response |
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| US6875757B2 (en) * | 2000-03-17 | 2005-04-05 | University Of Tennessee Research Foundation | LPA receptor agonists and antagonists and methods of use |
| EP1339390A2 (en) * | 2000-12-06 | 2003-09-03 | Pharmacia Corporation | Laboratory scale milling process |
| DE60234092D1 (de) * | 2001-01-30 | 2009-12-03 | Univ Virginia | Agonisten und antagonisten von sphingosin-1-phosphatrezeptoren |
| MXPA03008755A (es) | 2001-03-26 | 2004-02-18 | Novartis Ag | Derivados de 2-amino-propanol. |
| JP2002316985A (ja) | 2001-04-20 | 2002-10-31 | Sankyo Co Ltd | ベンゾチオフェン誘導体 |
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| BR0306811A (pt) | 2002-01-11 | 2004-10-26 | Sankyo Co | Composto, éster farmacologicamente aceitável do mesmo, composição farmacêutica e métodos para prevenção ou tratamento de doenças autoimunes, da artrite reumatóide e da rejeição causada pelo transplante de vários órgãos em um mamìfero |
| AU2003216054B2 (en) | 2002-01-18 | 2007-01-04 | Merck & Co., Inc. | Selective S1P1/Edg1 receptor agonists |
| GB0217152D0 (en) | 2002-07-24 | 2002-09-04 | Novartis Ag | Organic compounds |
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| AU2004240586A1 (en) | 2003-05-15 | 2004-12-02 | Merck & Co., Inc. | 3-(2-amino-1-azacyclyl)-5-aryl-1,2,4-oxadiazoles as S1P receptor agonists |
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| MXPA05012459A (es) * | 2003-05-19 | 2006-02-22 | Irm Llc | Compuestos y composiciones inmunosupresoras. |
| EP1481680A1 (en) * | 2003-05-30 | 2004-12-01 | Aventis Pharma Deutschland GmbH | Use of S1P |
| US20070043014A1 (en) | 2003-10-01 | 2007-02-22 | Merck & Co., Inc. | 3,5-Aryl, heteroaryl or cycloalkyl substituted-1,2,4-oxadiazoles as s1p receptor agonists |
| US7638637B2 (en) * | 2003-11-03 | 2009-12-29 | University Of Virginia Patent Foundation | Orally available sphingosine 1-phosphate receptor agonists and antagonists |
| GB0411929D0 (en) | 2004-05-27 | 2004-06-30 | Novartis Ag | Organic compounds |
| EP1760071A4 (en) | 2004-06-23 | 2008-03-05 | Ono Pharmaceutical Co | COMPOUND WITH S1P RECEPTOR BINDING ABILITY AND USE THEREOF |
| WO2006020951A1 (en) | 2004-08-13 | 2006-02-23 | Praecis Pharmaceuticals, Inc. | Methods and compositions for modulating sphingosine-1-phosphate (s1p) receptor activity |
| US20060223866A1 (en) * | 2004-08-13 | 2006-10-05 | Praecis Pharmaceuticals, Inc. | Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity |
| EP1827606A2 (en) * | 2004-12-06 | 2007-09-05 | University Of Virginia Patent Foundation | Aryl amide sphingosine 1-phosphate analogs |
| CA2596990A1 (en) * | 2005-02-14 | 2006-08-24 | University Of Virginia Patent Foundation | Sphingosine 1-phosphate agonists comprising cycloalkanes and 5 -membered heterocycles substituted by amino and phenyl groups |
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| AU2007323540A1 (en) | 2006-11-21 | 2008-05-29 | University Of Virginia Patent Foundation | Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity |
| CA2669124A1 (en) | 2006-11-21 | 2008-05-29 | University Of Virginia Patent Foundation | Benzocycloheptyl analogs having sphingosine 1-phosphate receptor activity |
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| JP2010536791A (ja) | 2007-08-15 | 2010-12-02 | ユニバーシティ オブ バージニア パテント ファンデーション | 二環式スフィンゴシン1−リン酸アナログ |
| CN101874015A (zh) | 2007-09-28 | 2010-10-27 | 弗吉尼亚大学专利基金会 | 苄基-环烷基鞘氨醇1-磷酸酯受体调节剂 |
| WO2009146112A1 (en) | 2008-04-02 | 2009-12-03 | University Of Virginia Patent Foundation | Compositions and methods for inhibiting sphingosine kinase |
-
2007
- 2007-01-29 AU AU2007209961A patent/AU2007209961A1/en not_active Abandoned
- 2007-01-29 JP JP2008552487A patent/JP2009528274A/ja active Pending
- 2007-01-29 KR KR1020087020888A patent/KR20080086546A/ko not_active Withdrawn
- 2007-01-29 CN CNA2007800037540A patent/CN101378741A/zh active Pending
- 2007-01-29 WO PCT/US2007/002422 patent/WO2007089715A2/en not_active Ceased
- 2007-01-29 EP EP07717121A patent/EP1986623A2/en not_active Withdrawn
- 2007-01-29 RU RU2008134702/04A patent/RU2008134702A/ru not_active Application Discontinuation
- 2007-01-29 CA CA002640366A patent/CA2640366A1/en not_active Abandoned
- 2007-01-29 BR BRPI0707281-3A patent/BRPI0707281A2/pt not_active IP Right Cessation
- 2007-01-29 MX MX2008009579A patent/MX2008009579A/es not_active Application Discontinuation
-
2008
- 2008-07-22 ZA ZA200806349A patent/ZA200806349B/xx unknown
- 2008-07-24 IL IL193040A patent/IL193040A0/en unknown
- 2008-07-25 US US12/179,816 patent/US8008286B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2640366A1 (en) | 2007-08-09 |
| KR20080086546A (ko) | 2008-09-25 |
| WO2007089715A2 (en) | 2007-08-09 |
| BRPI0707281A2 (pt) | 2011-04-26 |
| US8008286B2 (en) | 2011-08-30 |
| US20090062238A1 (en) | 2009-03-05 |
| AU2007209961A1 (en) | 2007-08-09 |
| WO2007089715A3 (en) | 2007-09-27 |
| CN101378741A (zh) | 2009-03-04 |
| RU2008134702A (ru) | 2010-03-10 |
| ZA200806349B (en) | 2009-06-24 |
| EP1986623A2 (en) | 2008-11-05 |
| JP2009528274A (ja) | 2009-08-06 |
| IL193040A0 (en) | 2009-02-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |