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MX2008003188A - Procedimiento para la preparacion de compuestos ester oxazolidina y su conversion a florfenicol. - Google Patents

Procedimiento para la preparacion de compuestos ester oxazolidina y su conversion a florfenicol.

Info

Publication number
MX2008003188A
MX2008003188A MX2008003188A MX2008003188A MX2008003188A MX 2008003188 A MX2008003188 A MX 2008003188A MX 2008003188 A MX2008003188 A MX 2008003188A MX 2008003188 A MX2008003188 A MX 2008003188A MX 2008003188 A MX2008003188 A MX 2008003188A
Authority
MX
Mexico
Prior art keywords
florfenicol
conversion
preparing ester
oxazolidine compounds
ester oxazolidine
Prior art date
Application number
MX2008003188A
Other languages
English (en)
Inventor
James C Towson
Original Assignee
Schering Plough Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough Ltd filed Critical Schering Plough Ltd
Publication of MX2008003188A publication Critical patent/MX2008003188A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se describe un procedimiento para la preparacion de compuestos de ester oxazolidina; estos compuestos son intermediarios utiles en el procedimiento para elaborar Florfenicol.
MX2008003188A 2005-09-07 2006-08-31 Procedimiento para la preparacion de compuestos ester oxazolidina y su conversion a florfenicol. MX2008003188A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71468505P 2005-09-07 2005-09-07
PCT/US2006/034370 WO2007030405A2 (en) 2005-09-07 2006-08-31 A process for preparing ester oxazolidine compounds and their conversion to florfenicol

Publications (1)

Publication Number Publication Date
MX2008003188A true MX2008003188A (es) 2008-03-18

Family

ID=37684114

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2008003188A MX2008003188A (es) 2005-09-07 2006-08-31 Procedimiento para la preparacion de compuestos ester oxazolidina y su conversion a florfenicol.
MX2008003187A MX2008003187A (es) 2005-09-07 2006-08-31 Un procedimiento mejorado para preparar compuestos de aminodiol protegidos con oxazodilina, utiles como intermediarios para el florfenicol.
MX2008003186A MX2008003186A (es) 2005-09-07 2006-08-31 Un procedimiento para preparar compuestos de aminodiol protegidos con oxazolidina utiles como intermediarios para florfenicol.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2008003187A MX2008003187A (es) 2005-09-07 2006-08-31 Un procedimiento mejorado para preparar compuestos de aminodiol protegidos con oxazodilina, utiles como intermediarios para el florfenicol.
MX2008003186A MX2008003186A (es) 2005-09-07 2006-08-31 Un procedimiento para preparar compuestos de aminodiol protegidos con oxazolidina utiles como intermediarios para florfenicol.

Country Status (19)

Country Link
US (3) US7786329B2 (es)
EP (3) EP1934189A2 (es)
JP (3) JP2009507074A (es)
KR (3) KR20080049039A (es)
CN (3) CN101300237A (es)
AU (3) AU2006287696A1 (es)
BR (3) BRPI0615764A2 (es)
CA (3) CA2621987A1 (es)
EC (3) ECSP088268A (es)
ES (1) ES2459205T3 (es)
IL (3) IL189828A0 (es)
MX (3) MX2008003188A (es)
NO (3) NO20081685L (es)
RU (3) RU2008112950A (es)
SI (1) SI1928820T1 (es)
TW (3) TW200804253A (es)
UA (1) UA93212C2 (es)
WO (3) WO2007030405A2 (es)
ZA (3) ZA200802047B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY146351A (en) 2003-05-29 2012-08-15 Schering Plough Ltd Compositions for treating infection in cattle and swine
EP1785414A1 (en) * 2005-11-09 2007-05-16 KRKA, tovarna zdravil, d.d., Novo mesto Process for the synthesis of intermediates of chloramphenicol or its analogues
CA2672795A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
CA2693922A1 (en) * 2007-07-25 2009-01-29 Intervet International B.V. Process for preparing oxazolidine-and oxazolidinone-aminodiols
US20090170954A1 (en) * 2007-12-14 2009-07-02 Schering-Plough Ltd. Process for Recovering Florfenicol and Florfenicol Analogs
CN102131772B (zh) * 2008-07-30 2015-03-11 英特威国际有限公司 用作氟苯尼考的中间体的*唑啉-保护的氨基二醇化合物的制备方法
CN101941927B (zh) * 2010-09-28 2012-10-03 湖北美天生物科技有限公司 氟苯尼考中间体(1r,2r)-2-氨基-1–(4-(甲砜基)苯基)-1,3-丙二醇的合成方法
AU2012251438A1 (en) 2011-05-02 2013-11-14 Pfizer Inc. Novel cephalosporins useful as antibacterial agents
CN103254103A (zh) * 2013-06-05 2013-08-21 南通金利油脂工业有限公司 氟化剂在制备氟苯尼考工艺中的应用
CN103965085B (zh) * 2014-04-17 2016-02-24 上海恒晟药业有限公司 一种取代1,2-氨基醇药物的制备方法
CN106278964B (zh) * 2016-07-31 2018-01-16 浙江润康药业有限公司 氟苯尼考的制备方法
CN111500652B (zh) * 2019-01-30 2024-03-26 苏州引航生物科技有限公司 一种制备氟苯尼考的方法
CN110302163A (zh) * 2019-07-23 2019-10-08 东莞正大康地饲料有限公司 一种氟苯尼考可溶性粉及其制备方法
CN110773207A (zh) * 2019-09-25 2020-02-11 陈红菊 一种在室温且无光条件下可完全分解甲醛的冷触媒材料及其制备方法
CN111423391A (zh) * 2020-03-18 2020-07-17 浙江康牧药业有限公司 一种氟苯尼考中间体的制备方法
CN113402475A (zh) * 2021-06-07 2021-09-17 山东国邦药业有限公司 一种氟苯尼考中间体的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002637A (en) * 1973-07-09 1977-01-11 Rohm And Haas Company Oxazolidine, oxazolidine-containing condensation and addition polymers and methods of producing them
EP0678506A3 (en) * 1983-06-02 1996-07-24 Zambon Spa Intermediates for the production of 1-phenyl-1-hydroxy-2-amino-3-fluoropropane derivatives.
IT1237798B (it) * 1989-10-20 1993-06-17 Zambon Spa Processo per l'inversione stereochimica di (2s,3s)-2-ammino-3-fenil-1 ,3-propandioli nei corrispondenti enantiomeri (2r,3r).
CA2142883A1 (en) * 1992-08-21 1994-03-03 Saizo Shibata Dioxacycloalkane compound having renin-inhibitory activity
US5663361A (en) * 1996-08-19 1997-09-02 Schering Corporation Process for preparing intermediates to florfenicol
JP2001240571A (ja) * 2000-03-01 2001-09-04 Udagawa Reiko フッ素アルコールの製造方法
BR0308289A (pt) * 2002-03-08 2005-01-11 Schering Plough Ltd Antibióticos do tipo florfenicol
US7126005B2 (en) * 2003-10-06 2006-10-24 Aurobindo Pharma Limited Process for preparing florfenicol

Also Published As

Publication number Publication date
IL189830A0 (en) 2008-11-03
TWI331139B (en) 2010-10-01
EP1928820B1 (en) 2014-01-29
MX2008003186A (es) 2008-03-18
MX2008003187A (es) 2008-03-18
US7786329B2 (en) 2010-08-31
ECSP088267A (es) 2008-04-28
ECSP088268A (es) 2008-04-28
TW200804253A (en) 2008-01-16
CN101300237A (zh) 2008-11-05
CN101300238A (zh) 2008-11-05
UA93212C2 (ru) 2011-01-25
ZA200802046B (en) 2008-12-31
BRPI0615767A2 (pt) 2011-05-24
WO2007030386A3 (en) 2007-05-24
TW200800924A (en) 2008-01-01
CA2621987A1 (en) 2007-03-15
JP2009507075A (ja) 2009-02-19
EP1934190A2 (en) 2008-06-25
US20070055066A1 (en) 2007-03-08
BRPI0615565A2 (pt) 2011-05-24
WO2007030386A2 (en) 2007-03-15
WO2007030405A3 (en) 2007-05-18
JP2009507842A (ja) 2009-02-26
RU2008112950A (ru) 2009-10-20
ES2459205T3 (es) 2014-05-08
ZA200802047B (en) 2008-12-31
ECSP088266A (es) 2008-04-28
CA2621971A1 (en) 2007-03-15
NO20081684L (no) 2008-06-05
KR101408596B1 (ko) 2014-06-17
KR20080049040A (ko) 2008-06-03
ZA200802048B (en) 2008-11-26
RU2008112946A (ru) 2009-10-20
WO2007030385A2 (en) 2007-03-15
US20070055080A1 (en) 2007-03-08
CA2621961A1 (en) 2007-03-15
CN101300227B (zh) 2013-07-03
WO2007030405A2 (en) 2007-03-15
IL189828A0 (en) 2008-11-03
WO2007030385A3 (en) 2007-05-24
RU2008112952A (ru) 2009-10-20
AU2006287697A1 (en) 2007-03-15
KR20080049039A (ko) 2008-06-03
CN101300227A (zh) 2008-11-05
KR20080041699A (ko) 2008-05-13
SI1928820T1 (sl) 2014-08-29
BRPI0615764A2 (pt) 2011-05-24
JP5113754B2 (ja) 2013-01-09
NO20081685L (no) 2008-06-05
JP2009507074A (ja) 2009-02-19
EP1934189A2 (en) 2008-06-25
NO20081686L (no) 2008-06-05
AU2006287696A1 (en) 2007-03-15
US20070055067A1 (en) 2007-03-08
AU2006287716A1 (en) 2007-03-15
TW200804254A (en) 2008-01-16
IL189829A0 (en) 2008-11-03
EP1928820A2 (en) 2008-06-11

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