MX2008002275A - Asociacion de un agente hipnotico de duracion de accion larga y un agente hipnotico de duracion de accion corta y su aplicacion en terapeutica. - Google Patents
Asociacion de un agente hipnotico de duracion de accion larga y un agente hipnotico de duracion de accion corta y su aplicacion en terapeutica.Info
- Publication number
- MX2008002275A MX2008002275A MX2008002275A MX2008002275A MX2008002275A MX 2008002275 A MX2008002275 A MX 2008002275A MX 2008002275 A MX2008002275 A MX 2008002275A MX 2008002275 A MX2008002275 A MX 2008002275A MX 2008002275 A MX2008002275 A MX 2008002275A
- Authority
- MX
- Mexico
- Prior art keywords
- hypnotic agent
- acting hypnotic
- combination
- short
- long
- Prior art date
Links
- 239000003326 hypnotic agent Substances 0.000 title abstract 4
- 230000001225 therapeutic effect Effects 0.000 title 1
- 102000005962 receptors Human genes 0.000 abstract 3
- 108020003175 receptors Proteins 0.000 abstract 3
- SVUOLADPCWQTTE-UHFFFAOYSA-N 1h-1,2-benzodiazepine Chemical compound N1N=CC=CC2=CC=CC=C12 SVUOLADPCWQTTE-UHFFFAOYSA-N 0.000 abstract 2
- 229940049706 benzodiazepine Drugs 0.000 abstract 2
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 abstract 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 abstract 1
- 229940121723 Melatonin receptor agonist Drugs 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 229910001424 calcium ion Inorganic materials 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical class COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 abstract 1
- 239000002974 melatonin derivative Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229950000688 phenothiazine Drugs 0.000 abstract 1
- 208000019116 sleep disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La invencion se refiere a la asociacion de un agente hipnotico de duracion de accion corta elegida entre un modulador de los receptores GABA-A, una benzodiazepina, las fenotiazinas, un derivados de la melatonina un agonistas de los receptores de la melatonina y de un agente hipnotico de duracion de accion larga elegida entre un modulador de los receptores GABA-A, una benzodiazepina, un antagonista de los receptores 5HT2A, un modulador de los iones calcio para tratar los trastornos de sueno. La invencion se refiere igualmente alas formulaciones galenicas que encierran esta asociacion.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0508643A FR2889811B1 (fr) | 2005-08-19 | 2005-08-19 | Association d'un agent hypnotique a duree d'action longue et d'un agent hypnotique a duree d'action courte, composition pharmaceutique la contenant et son application en therapeutique. |
| PCT/FR2006/001830 WO2007020337A1 (fr) | 2005-08-19 | 2006-07-27 | Association d'un agent hypnotique a duree d'action longue et d'un agent hypnotique a duree d'action courte et son application therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008002275A true MX2008002275A (es) | 2008-03-27 |
Family
ID=36273351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008002275A MX2008002275A (es) | 2005-08-19 | 2006-07-27 | Asociacion de un agente hipnotico de duracion de accion larga y un agente hipnotico de duracion de accion corta y su aplicacion en terapeutica. |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US20080181943A1 (es) |
| EP (1) | EP1919473B1 (es) |
| JP (1) | JP5215851B2 (es) |
| KR (1) | KR20080039909A (es) |
| CN (1) | CN101267819B (es) |
| AR (1) | AR055123A1 (es) |
| AU (1) | AU2006281334B2 (es) |
| BR (1) | BRPI0614792A2 (es) |
| CA (1) | CA2618212C (es) |
| CR (1) | CR9695A (es) |
| EA (1) | EA014294B1 (es) |
| EC (1) | ECSP088131A (es) |
| FR (1) | FR2889811B1 (es) |
| HN (1) | HN2008000278A (es) |
| IL (1) | IL188823A0 (es) |
| MA (1) | MA29766B1 (es) |
| MX (1) | MX2008002275A (es) |
| NO (1) | NO20081250L (es) |
| NZ (1) | NZ565880A (es) |
| SG (1) | SG165316A1 (es) |
| TN (1) | TNSN08027A1 (es) |
| TW (1) | TW200738238A (es) |
| UA (1) | UA93209C2 (es) |
| WO (1) | WO2007020337A1 (es) |
| ZA (1) | ZA200800968B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200626137A (en) * | 2004-12-13 | 2006-08-01 | Takeda Pharmaceuticals Co | Preventive or therapeutic agent for sleep disorder |
| WO2009084023A2 (en) * | 2007-10-19 | 2009-07-09 | Glenmark Generics Limited | Amorphous ramelteon and process for the preparation thereof |
| WO2009082268A2 (ru) | 2007-12-21 | 2009-07-02 | Alla Chem, Llc | ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ |
| US20120108669A1 (en) * | 2008-11-13 | 2012-05-03 | Sanofi-Aventis | Method of treating sleep disorders using eplivanserin |
| FR2938534B1 (fr) | 2008-11-14 | 2012-10-26 | Sanofi Aventis | Procede de preparation de l'hemifumarate d'eplivanserine |
| US20100196286A1 (en) * | 2008-12-01 | 2010-08-05 | Armer Thomas A | Inhalation delivery methods and devices |
| US8555875B2 (en) | 2008-12-23 | 2013-10-15 | Map Pharmaceuticals, Inc. | Inhalation devices and related methods for administration of sedative hypnotic compounds |
| JP5726766B2 (ja) | 2009-02-13 | 2015-06-03 | ロマーク ラボラトリーズ エル.シー. | ニタゾキサニドの制御放出医薬配合物 |
| EP2255726A1 (en) * | 2009-05-26 | 2010-12-01 | Sanofi-Aventis | Spectral profile of SWS enhancing drugs |
| EP2255807A1 (en) * | 2009-05-26 | 2010-12-01 | Sanofi-Aventis | Method of treating sleep disorders using the combination of eplivanserin and zolpidem |
| WO2012109695A1 (en) * | 2011-02-16 | 2012-08-23 | Casal Y Galzov Ramon Ernesto | Drug compositions for the treatment of insomnia |
| US9700548B2 (en) | 2011-06-09 | 2017-07-11 | Requis Pharmaceuticals Inc. | Antihistamines combined with dietary supplements for improved health |
| CN102579383A (zh) * | 2012-04-09 | 2012-07-18 | 南京正科制药有限公司 | 右佐匹克隆缓释片 |
| PT3102189T (pt) * | 2014-02-06 | 2019-12-11 | Bo Chen Lan | Composição e método para melhorar o sono |
| CN108289849A (zh) | 2015-06-26 | 2018-07-17 | 韩国联合制药株式会社 | 莫沙必利与雷贝拉唑的复合制剂 |
| CN105596313B (zh) * | 2016-02-17 | 2018-06-29 | 新乡医学院第一附属医院 | 一种具有反向药理功能的用于治疗失眠的胶囊制剂 |
| CN105997958B (zh) * | 2016-07-12 | 2019-03-26 | 中国人民解放军白求恩医务士官学校 | 一种口腔外用制剂及其制备方法 |
| RS61024B1 (sr) * | 2016-10-31 | 2020-12-31 | Neurim Pharma 1991 | Mini-tablete melatonina i postupak za njihovu proizvodnju |
| JP7053665B2 (ja) * | 2016-12-30 | 2022-04-12 | 南京明徳新薬研発有限公司 | Egfr阻害としてのキナゾリン系化合物 |
| CN118384147A (zh) | 2018-01-30 | 2024-07-26 | 爱普宁公司(特拉华) | 用于治疗睡眠呼吸暂停的方法和组合物 |
| AU2019384157A1 (en) | 2018-11-21 | 2021-06-17 | Certego Therapeutics Inc. | Gaboxadol for reducing risk of suicide and rapid relief of depression |
| CA3129270A1 (en) * | 2019-02-08 | 2020-08-13 | The Brigham And Women's Hospital, Inc. | Methods and compositions for treating sleep apnea |
| WO2021236876A2 (en) | 2020-05-20 | 2021-11-25 | Certego Therapeutics Inc. | Ring deuterated gaboxadol and its use for the treatment of psychiatric disorders |
| FR3116439B1 (fr) * | 2020-11-26 | 2023-08-04 | Laboratoire Dielen | Comprimé pelliculé contenant au moins un principe actif, adapté à l’administration par voie orale dudit au moins un principe actif chez des sujets humains |
| CN115919806A (zh) * | 2022-12-22 | 2023-04-07 | 南京乐韬生物科技有限公司 | 一种gaba缓释胶囊的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4060599A (en) * | 1998-06-09 | 1999-12-30 | Takeda Chemical Industries Ltd. | Pharmaceutical composition for treating or preventing sleep disorders |
| JP3509637B2 (ja) * | 1998-06-09 | 2004-03-22 | 武田薬品工業株式会社 | 睡眠障害予防治療剤 |
| EP1005863A1 (en) * | 1998-12-04 | 2000-06-07 | Synthelabo | Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof |
| DK1691811T3 (da) * | 2003-12-11 | 2014-10-20 | Sunovion Pharmaceuticals Inc | Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression |
| WO2005063297A2 (en) * | 2003-12-24 | 2005-07-14 | Sepracor Inc. | Melatonin combination therapy for improving sleep quality |
| TW200626137A (en) * | 2004-12-13 | 2006-08-01 | Takeda Pharmaceuticals Co | Preventive or therapeutic agent for sleep disorder |
| CA2614244A1 (en) * | 2005-07-06 | 2007-01-11 | Sepracor Inc. | Combinations of eszopiclone and an antidepressant |
| EP1937265A2 (en) * | 2005-08-19 | 2008-07-02 | Aventis Pharmaceuticals Inc. | Comination of a hypnotic agent and r(+)-alpha-(2,3-dimethoxy-phenyl)-1-[2-(4-fluorophenl)ethyl]-4-piperidinemethanol and therapeutic application thereof |
| SG140147A1 (en) * | 2005-08-19 | 2008-03-28 | Aventis Pharma Inc | Combination of a hypnotic agent and substituted bis aryl and heteroaryl compound and therapeutic application thereof |
-
2005
- 2005-08-19 FR FR0508643A patent/FR2889811B1/fr not_active Expired - Fee Related
-
2006
- 2006-07-27 ZA ZA200800968A patent/ZA200800968B/xx unknown
- 2006-07-27 MX MX2008002275A patent/MX2008002275A/es active IP Right Grant
- 2006-07-27 CA CA2618212A patent/CA2618212C/fr not_active Expired - Fee Related
- 2006-07-27 CN CN2006800342549A patent/CN101267819B/zh not_active Expired - Fee Related
- 2006-07-27 EP EP06794228A patent/EP1919473B1/fr active Active
- 2006-07-27 UA UAA200803488A patent/UA93209C2/ru unknown
- 2006-07-27 AU AU2006281334A patent/AU2006281334B2/en not_active Ceased
- 2006-07-27 BR BRPI0614792-5A patent/BRPI0614792A2/pt not_active IP Right Cessation
- 2006-07-27 EA EA200800618A patent/EA014294B1/ru not_active IP Right Cessation
- 2006-07-27 SG SG201006201-6A patent/SG165316A1/en unknown
- 2006-07-27 WO PCT/FR2006/001830 patent/WO2007020337A1/fr not_active Ceased
- 2006-07-27 JP JP2008526520A patent/JP5215851B2/ja not_active Expired - Fee Related
- 2006-07-27 NZ NZ565880A patent/NZ565880A/en not_active IP Right Cessation
- 2006-07-27 KR KR1020087003865A patent/KR20080039909A/ko not_active Abandoned
- 2006-08-16 TW TW095130112A patent/TW200738238A/zh unknown
- 2006-08-17 AR ARP060103587A patent/AR055123A1/es not_active Application Discontinuation
-
2008
- 2008-01-16 IL IL188823A patent/IL188823A0/en unknown
- 2008-01-18 TN TNP2008000027A patent/TNSN08027A1/en unknown
- 2008-01-22 EC EC2008008131A patent/ECSP088131A/es unknown
- 2008-01-28 CR CR9695A patent/CR9695A/es not_active Application Discontinuation
- 2008-02-11 US US12/029,011 patent/US20080181943A1/en not_active Abandoned
- 2008-02-19 HN HN2008000278A patent/HN2008000278A/es unknown
- 2008-03-07 MA MA30725A patent/MA29766B1/fr unknown
- 2008-03-10 NO NO20081250A patent/NO20081250L/no not_active Application Discontinuation
-
2010
- 2010-07-29 US US12/846,078 patent/US20100291204A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| FR2889811A1 (fr) | 2007-02-23 |
| KR20080039909A (ko) | 2008-05-07 |
| EP1919473B1 (fr) | 2012-12-05 |
| JP5215851B2 (ja) | 2013-06-19 |
| HK1124541A1 (en) | 2009-07-17 |
| AU2006281334B2 (en) | 2012-10-18 |
| ECSP088131A (es) | 2008-02-20 |
| IL188823A0 (en) | 2008-12-29 |
| EA014294B1 (ru) | 2010-10-29 |
| UA93209C2 (ru) | 2011-01-25 |
| AU2006281334A1 (en) | 2007-02-22 |
| CA2618212A1 (fr) | 2007-02-22 |
| CA2618212C (fr) | 2014-03-25 |
| FR2889811B1 (fr) | 2009-10-09 |
| WO2007020337A1 (fr) | 2007-02-22 |
| CN101267819B (zh) | 2012-05-30 |
| JP2009504713A (ja) | 2009-02-05 |
| EA200800618A1 (ru) | 2008-06-30 |
| AR055123A1 (es) | 2007-08-08 |
| ZA200800968B (en) | 2009-04-29 |
| HN2008000278A (es) | 2011-03-30 |
| MA29766B1 (fr) | 2008-09-01 |
| US20080181943A1 (en) | 2008-07-31 |
| NZ565880A (en) | 2011-07-29 |
| CR9695A (es) | 2008-02-20 |
| SG165316A1 (en) | 2010-10-28 |
| TNSN08027A1 (en) | 2009-07-14 |
| TW200738238A (en) | 2007-10-16 |
| CN101267819A (zh) | 2008-09-17 |
| US20100291204A1 (en) | 2010-11-18 |
| NO20081250L (no) | 2008-05-13 |
| EP1919473A1 (fr) | 2008-05-14 |
| BRPI0614792A2 (pt) | 2011-04-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TNSN08027A1 (en) | Combination of a long-acting hypnotic agent and a short-acting hypnotic agent and therapeutic use of same | |
| SV2005002148A (es) | "compuestos moduladores de la actividad c-kit y usos de los mismos" | |
| AP1542A (en) | Glucocorticoid receptor modulators. | |
| BRPI0418092A (pt) | combinação terapêutica para melhora cognitiva e transtornos psicóticos | |
| IL184932A0 (en) | Glucagon receptor antagonists, preperation and therapeutic uses | |
| IL181700A0 (en) | Quinazoline derivatives and pharmaceutical compositions containing the same | |
| MXPA05013733A (es) | 2-aminobenzotiazoles como agonistas inversos del receptor de cb1. | |
| EA200970302A1 (ru) | Тиофенпиразолопиримидиновые соединения | |
| BR0104834A (pt) | Moduladores de receptores de glucocorticóides | |
| SV2009003212A (es) | Inhibidores de metaloproteasa derivados de heterociclicos ref. prd2727svpct | |
| BR0314488A (pt) | Composto, composição farmacêutica e métodos de tratamento | |
| IL188942A0 (en) | Benzimidazole derivatives and pharmaceutical compositions containing the same | |
| ATE327974T1 (de) | Modulatoren des glucocorticoid-rezeptors | |
| DK1551803T3 (da) | Azabicycloderivater som muskarine receptorantagonister | |
| EA200700027A1 (ru) | Антагонисты рецептора глюкагона, их получение и терапевтическое применение | |
| BRPI0517438A (pt) | composto, método para tratar a condição associada com atividade de receptor muscarìnico m4, uso do composto, e, composição farmacêutica | |
| HRP20041014B1 (hr) | Novi spojevi kao modulatori opioidnog receptora | |
| PT1673354E (pt) | Arilindenopiridinas e arilindenopirimidinas e sua utilização como antagonistas do receptor da adenosina a2a | |
| TW200631956A (en) | Azabenzoxazoles for the treatment of CNS disorders | |
| IL179206A0 (en) | Pyrrolylpyrimidine derivatives and pharmaceutical compositions containing the same | |
| MX2007003545A (es) | Composiciones y metodos para tratar trastornos cognitivos. | |
| EA200601592A1 (ru) | Фармацевтическая композиция, содержащая ингибитор pde4 или pde3/4 и антагонист гистаминового рецептора | |
| IL183339A0 (en) | Pyrolidine-2-one derivatives and pharmaceutical compositions containing them | |
| YU60803A (sh) | Upotreba antagonista gal3 receptora u lečenju depresije i/ili uznemirenosti i jedinjenja korisna u tim postupcima | |
| AU2003288858A1 (en) | Use of cyclolignans as inhibitors of igf-1 receptor for treatment of malignat diseases |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |