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MX2007010778A - Estabilizacion de actividad de enzima en biosensores electroquimicos. - Google Patents

Estabilizacion de actividad de enzima en biosensores electroquimicos.

Info

Publication number
MX2007010778A
MX2007010778A MX2007010778A MX2007010778A MX2007010778A MX 2007010778 A MX2007010778 A MX 2007010778A MX 2007010778 A MX2007010778 A MX 2007010778A MX 2007010778 A MX2007010778 A MX 2007010778A MX 2007010778 A MX2007010778 A MX 2007010778A
Authority
MX
Mexico
Prior art keywords
pqq
activity
stabilizing
electrochemical biosensors
glucose dehydrogenase
Prior art date
Application number
MX2007010778A
Other languages
English (en)
Inventor
Amy H Chu
Hope G Spradlin
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Publication of MX2007010778A publication Critical patent/MX2007010778A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/005Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006Enzyme electrodes involving specific analytes or enzymes for glucose
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/004Enzyme electrodes mediator-assisted
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Una composicion reactiva que contiene GDH-PQQ como una enzima-co-factor y es impresa por serigrafia sobre electrodos de trabajo y controlaelectrodos de biosensores electroquimicos, mantiene la actividad de los reactivos de la enzima a traves de la seleccion adecuada de los componentes. Una composicion preferida incluye polimeros hidrofilicos, silice amorfa no tratada, amortiguadores, surfactantes y un mediador. La figura mas representativa de la invencion es la numero 1a.
MX2007010778A 2005-03-04 2006-03-03 Estabilizacion de actividad de enzima en biosensores electroquimicos. MX2007010778A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65863405P 2005-03-04 2005-03-04
PCT/US2006/007875 WO2006096619A2 (en) 2005-03-04 2006-03-03 Stabilizing the activity of pqq-dependent glucose dehydrogenase in electrochemical biosensors

Publications (1)

Publication Number Publication Date
MX2007010778A true MX2007010778A (es) 2007-11-07

Family

ID=36677188

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007010778A MX2007010778A (es) 2005-03-04 2006-03-03 Estabilizacion de actividad de enzima en biosensores electroquimicos.

Country Status (14)

Country Link
US (3) US8921065B2 (es)
EP (1) EP1859048B1 (es)
JP (2) JP5020832B2 (es)
KR (1) KR20070114802A (es)
CN (1) CN101133162A (es)
AU (1) AU2006220770A1 (es)
BR (1) BRPI0607841A2 (es)
CA (1) CA2600132C (es)
MX (1) MX2007010778A (es)
NO (1) NO20074925L (es)
RU (1) RU2422534C2 (es)
TW (1) TW200643173A (es)
WO (1) WO2006096619A2 (es)
ZA (1) ZA200708312B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2402578T3 (es) * 2005-11-14 2013-05-06 Bayer Healthcare, Llc Reactivo de sensor de ensayo que tiene polímeros de celulosa
RU2450263C2 (ru) * 2006-09-22 2012-05-10 БАЙЕР ХЕЛТКЭА ЭлЭлСи Биосенсорная система, обладающая повышенной стабильностью и гематокритной эффективностью
EP2222866A1 (en) 2007-12-10 2010-09-01 Bayer HealthCare LLC Reagents and methods for detecting analytes
WO2009076412A1 (en) * 2007-12-10 2009-06-18 Bayer Healthcare Llc Method of depositing reagent material in a test sensor
US7678250B2 (en) * 2008-01-22 2010-03-16 Home Diagnostics, Inc. Reagent compositions for use in electrochemical detection
PL2318837T4 (pl) 2008-07-11 2016-10-31 Wzmocniony czujnik testu immunologicznego
US20100270152A1 (en) * 2009-04-24 2010-10-28 Lifescan Scotland Limited Enzymatic reagent ink
US8025788B2 (en) * 2009-04-24 2011-09-27 Lifescan Scotland Limited Method for manufacturing an enzymatic reagent ink
US20100273249A1 (en) * 2009-04-24 2010-10-28 Lifescan Scotland Limited Analytical test strips
US8409412B2 (en) 2010-08-23 2013-04-02 Lifescan Scotland, Ltd. Enzymatic reagent inks for use in test strips having a predetermined calibration code
KR20140064771A (ko) * 2011-07-06 2014-05-28 어드밴스드 리퀴드 로직, 아이엔씨. 비말 작동기 상의 시약 저장
KR101239381B1 (ko) 2012-05-02 2013-03-05 주식회사 아이센스 산화환원반응용 시약의 안정제 조성물
US9097659B2 (en) * 2013-03-14 2015-08-04 Bayer Healthcare Llc Maintaining electrode function during manufacture with a protective layer
MX2017015094A (es) * 2015-06-01 2018-08-14 Univ Queensland Biosensor electroquimico.
CN108802157A (zh) * 2018-06-22 2018-11-13 桂林中辉科技发展有限公司 一种总胆汁酸检测试剂、试纸及检测方法与应用
US20220225911A1 (en) * 2019-05-28 2022-07-21 W. L. Gore & Associates, Inc. Stabilized medical devices and associated methods
CN114923965B (zh) * 2022-03-18 2023-05-23 杭州微策生物技术股份有限公司 一种一体式多指标传感器及其制作方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5682884A (en) * 1983-05-05 1997-11-04 Medisense, Inc. Strip electrode with screen printing
WO1989009397A1 (en) * 1988-03-31 1989-10-05 Matsushita Electric Industrial Co., Ltd. Biosensor and process for its production
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5320732A (en) * 1990-07-20 1994-06-14 Matsushita Electric Industrial Co., Ltd. Biosensor and measuring apparatus using the same
US5429735A (en) * 1994-06-27 1995-07-04 Miles Inc. Method of making and amperometric electrodes
JP3775518B2 (ja) * 1995-11-22 2006-05-17 東洋紡績株式会社 Pqq依存性グルコースデヒドロゲナーゼ組成物およびグルコース測定用試薬組成物
US5708247A (en) * 1996-02-14 1998-01-13 Selfcare, Inc. Disposable glucose test strips, and methods and compositions for making same
US6241862B1 (en) * 1996-02-14 2001-06-05 Inverness Medical Technology, Inc. Disposable test strips with integrated reagent/blood separation layer
JP3370504B2 (ja) * 1996-03-13 2003-01-27 松下電器産業株式会社 バイオセンサ
US5660791A (en) * 1996-06-06 1997-08-26 Bayer Corporation Fluid testing sensor for use in dispensing instrument
US6059946A (en) * 1997-04-14 2000-05-09 Matsushita Electric Industrial Co., Ltd. Biosensor
US5798031A (en) * 1997-05-12 1998-08-25 Bayer Corporation Electrochemical biosensor
US6736957B1 (en) * 1997-10-16 2004-05-18 Abbott Laboratories Biosensor electrode mediators for regeneration of cofactors and process for using
US5997817A (en) * 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
US7407811B2 (en) * 1997-12-22 2008-08-05 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC excitation
US6656702B1 (en) * 1998-07-03 2003-12-02 Matsushita Electric Industrial Co., Ltd. Biosensor containing glucose dehydrogenase
JP3694424B2 (ja) * 1998-09-29 2005-09-14 松下電器産業株式会社 グルコースセンサ
DE19849000A1 (de) * 1998-10-23 2000-04-27 Roche Diagnostics Gmbh Funktionsschichten mit hoher Präzision, Verfahren zu ihrer Herstellung und Teststreifen enthaltend diese Funktionsschichten
CA2305922C (en) * 1999-08-02 2005-09-20 Bayer Corporation Improved electrochemical sensor design
DE60024965T2 (de) * 1999-10-05 2006-07-13 Matsushita Electric Industrial Co., Ltd., Kadoma Glukosesensor
US6627057B1 (en) * 1999-12-23 2003-09-30 Roche Diagnostic Corporation Microsphere containing sensor
US6780296B1 (en) * 1999-12-23 2004-08-24 Roche Diagnostics Corporation Thermally conductive sensor
DE60019547T2 (de) * 1999-12-27 2005-10-06 Matsushita Electric Industrial Co., Ltd., Kadoma Biosensor
KR100554649B1 (ko) * 2003-06-09 2006-02-24 주식회사 아이센스 전기화학적 바이오센서
WO2004113902A1 (en) 2003-06-20 2004-12-29 Roche Diagnostics Gmbh Reagent stripe for test strip
WO2005045415A1 (en) * 2003-10-31 2005-05-19 Lifescan Scotland Limited A meter for use in an improved method of reducing interferences in an electrochemical sensor using two different applied potentials

Also Published As

Publication number Publication date
US20190249214A1 (en) 2019-08-15
WO2006096619A3 (en) 2006-11-23
US20080199937A1 (en) 2008-08-21
ZA200708312B (en) 2008-11-26
CA2600132A1 (en) 2006-09-14
US20150076003A1 (en) 2015-03-19
JP2012198218A (ja) 2012-10-18
EP1859048A2 (en) 2007-11-28
RU2007136760A (ru) 2009-04-10
KR20070114802A (ko) 2007-12-04
RU2422534C2 (ru) 2011-06-27
JP5020832B2 (ja) 2012-09-05
WO2006096619A2 (en) 2006-09-14
JP2008532047A (ja) 2008-08-14
US8921065B2 (en) 2014-12-30
TW200643173A (en) 2006-12-16
EP1859048B1 (en) 2014-06-18
NO20074925L (no) 2007-11-02
BRPI0607841A2 (pt) 2009-06-13
JP5236824B2 (ja) 2013-07-17
AU2006220770A1 (en) 2006-09-14
CA2600132C (en) 2014-09-09
CN101133162A (zh) 2008-02-27

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