MX2007009914A - Uso de agonistas selectivos para el receptor-beta de estrogeno para la mucositis inducida por radiacion o por quimioterapia y para la cistitis inducida por radiacion. - Google Patents
Uso de agonistas selectivos para el receptor-beta de estrogeno para la mucositis inducida por radiacion o por quimioterapia y para la cistitis inducida por radiacion.Info
- Publication number
- MX2007009914A MX2007009914A MX2007009914A MX2007009914A MX2007009914A MX 2007009914 A MX2007009914 A MX 2007009914A MX 2007009914 A MX2007009914 A MX 2007009914A MX 2007009914 A MX2007009914 A MX 2007009914A MX 2007009914 A MX2007009914 A MX 2007009914A
- Authority
- MX
- Mexico
- Prior art keywords
- radiation
- mucosistis
- chemotherapy
- induced
- estrogen receptor
- Prior art date
Links
- 201000007608 radiation cystitis Diseases 0.000 title abstract 3
- 239000000556 agonist Substances 0.000 title 1
- 238000002512 chemotherapy Methods 0.000 title 1
- 229940011871 estrogen Drugs 0.000 title 1
- 239000000262 estrogen Substances 0.000 title 1
- 238000001959 radiotherapy Methods 0.000 title 1
- 206010028116 Mucosal inflammation Diseases 0.000 abstract 2
- 201000010927 Mucositis Diseases 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
La presente invencion provee un metodo para tratar o inhibir la mucositis o la cistitis por radiacion, utilizando un ligando selectivo para ER??; la presente invencion tambien provee composiciones, incluyendo composiciones farmaceuticas, que contienen el ligando selectivo para ER?? y un medicamento tradicional para la mucositis o cistitis por radiacion.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65337605P | 2005-02-16 | 2005-02-16 | |
| PCT/US2006/005000 WO2006088784A1 (en) | 2005-02-16 | 2006-02-14 | Use of estrogen receptor-b selective agonists for radiation-or chemotherapy-induced mucosistis and radiation cystitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007009914A true MX2007009914A (es) | 2007-09-25 |
Family
ID=36597596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007009914A MX2007009914A (es) | 2005-02-16 | 2006-02-14 | Uso de agonistas selectivos para el receptor-beta de estrogeno para la mucositis inducida por radiacion o por quimioterapia y para la cistitis inducida por radiacion. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20060211672A1 (es) |
| EP (1) | EP1848427A1 (es) |
| JP (1) | JP2008530210A (es) |
| KR (1) | KR20070103456A (es) |
| CN (1) | CN101119721A (es) |
| AR (1) | AR053332A1 (es) |
| AU (1) | AU2006214515A1 (es) |
| BR (1) | BRPI0608154A2 (es) |
| CA (1) | CA2596984A1 (es) |
| CR (1) | CR9263A (es) |
| GT (1) | GT200600064A (es) |
| IL (1) | IL185009A0 (es) |
| MX (1) | MX2007009914A (es) |
| NI (1) | NI200700182A (es) |
| NO (1) | NO20073901L (es) |
| PE (1) | PE20061092A1 (es) |
| RU (1) | RU2007128819A (es) |
| TW (1) | TW200640451A (es) |
| WO (1) | WO2006088784A1 (es) |
| ZA (1) | ZA200706785B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0707655A2 (pt) * | 2006-02-14 | 2011-05-10 | Wyeth Corp | composiÇço farmacÊutica aquosa, mÉtodo para preparar uma composiÇço farmacÊutica, produto, mÉtodo para tratar um indivÍduo sofrendo de artrite ou endometriose, e, kit |
| US9604931B2 (en) | 2007-01-22 | 2017-03-28 | Gtx, Inc. | Nuclear receptor binding agents |
| KR101763674B1 (ko) | 2007-01-22 | 2017-08-01 | 지티엑스, 인코포레이티드 | 핵 수용체에 결합하는 물질 |
| US9623021B2 (en) * | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
| US20150018398A1 (en) * | 2013-07-15 | 2015-01-15 | The Regents Of The University Of California | Methods of using estrogen receptor-beta ligands as radiation mitigators |
| EP3906508B1 (en) * | 2018-12-31 | 2024-03-13 | Intel Corporation | Securing systems employing artificial intelligence |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5496828A (en) * | 1994-08-22 | 1996-03-05 | Eli Lilly And Company | Methods of inhibiting ulcerative mucositis |
| JP2000506529A (ja) * | 1996-03-11 | 2000-05-30 | イーライ・リリー・アンド・カンパニー | 間質性膀胱炎の処置または予防方法 |
| SK9592002A3 (en) * | 2000-01-28 | 2003-12-02 | Endorech Inc | A method for reduction or elimination of the incidence of menopausal symptoms, method of treatment or decreasing the risk of an acquiring disease, a pharmaceutical composition and a kit |
| MXPA03004546A (es) * | 2000-11-22 | 2003-09-10 | Rxkinetix Inc | Tratamiento de mucositis. |
| PT1997478E (pt) * | 2001-02-15 | 2013-12-10 | Access Pharma Inc | Formulações líquidas para a prevenção e para o tratamento de doenças e distúrbios das mucosas |
| UA83620C2 (ru) * | 2001-12-05 | 2008-08-11 | Уайт | Замещенные бензоксазолы и их аналоги как эстрогенные агенты |
| US6914074B2 (en) * | 2001-12-13 | 2005-07-05 | Wyeth | Substituted phenyl naphthalenes as estrogenic agents |
| TW200301107A (en) * | 2001-12-13 | 2003-07-01 | Wyeth Corp | Substituted 6H-dibenzo[c,h]chromenes as estrogenic agents |
| US20030220377A1 (en) * | 2002-05-08 | 2003-11-27 | Richard Chesworth | Indole compounds and their use as estrogen agonists/antagonists |
| CL2004000985A1 (es) * | 2003-05-16 | 2005-01-14 | Wyeth Corp | Compuestos derivados de fenilquinolinas; composicion farmaceutica, proceso de preparacion; y uso para tratar osteoporosis, enfermedad de paget, dano vascular, osteoartritis, cancer oseo, cancer ovarico, cancer prostatico, hipercolesterolemia, aterosc |
-
2006
- 2006-02-14 CA CA002596984A patent/CA2596984A1/en not_active Abandoned
- 2006-02-14 GT GT200600064A patent/GT200600064A/es unknown
- 2006-02-14 AR ARP060100515A patent/AR053332A1/es not_active Application Discontinuation
- 2006-02-14 KR KR1020077018755A patent/KR20070103456A/ko not_active Withdrawn
- 2006-02-14 BR BRPI0608154A patent/BRPI0608154A2/pt not_active IP Right Cessation
- 2006-02-14 MX MX2007009914A patent/MX2007009914A/es unknown
- 2006-02-14 TW TW095104866A patent/TW200640451A/zh unknown
- 2006-02-14 WO PCT/US2006/005000 patent/WO2006088784A1/en not_active Ceased
- 2006-02-14 CN CNA2006800049774A patent/CN101119721A/zh active Pending
- 2006-02-14 AU AU2006214515A patent/AU2006214515A1/en not_active Abandoned
- 2006-02-14 RU RU2007128819/14A patent/RU2007128819A/ru unknown
- 2006-02-14 JP JP2007556226A patent/JP2008530210A/ja active Pending
- 2006-02-14 US US11/353,611 patent/US20060211672A1/en not_active Abandoned
- 2006-02-14 EP EP06734914A patent/EP1848427A1/en not_active Withdrawn
- 2006-02-14 PE PE2006000172A patent/PE20061092A1/es not_active Application Discontinuation
-
2007
- 2007-07-20 CR CR9263A patent/CR9263A/es not_active Application Discontinuation
- 2007-07-25 NI NI200700182A patent/NI200700182A/es unknown
- 2007-07-25 NO NO20073901A patent/NO20073901L/no not_active Application Discontinuation
- 2007-08-02 IL IL185009A patent/IL185009A0/en unknown
- 2007-08-15 ZA ZA200706785A patent/ZA200706785B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20073901L (no) | 2007-11-15 |
| AR053332A1 (es) | 2007-05-02 |
| NI200700182A (es) | 2008-05-13 |
| CN101119721A (zh) | 2008-02-06 |
| WO2006088784A1 (en) | 2006-08-24 |
| EP1848427A1 (en) | 2007-10-31 |
| IL185009A0 (en) | 2008-08-07 |
| US20060211672A1 (en) | 2006-09-21 |
| AU2006214515A1 (en) | 2006-08-24 |
| TW200640451A (en) | 2006-12-01 |
| BRPI0608154A2 (pt) | 2016-10-11 |
| KR20070103456A (ko) | 2007-10-23 |
| GT200600064A (es) | 2006-11-09 |
| JP2008530210A (ja) | 2008-08-07 |
| CR9263A (es) | 2007-11-23 |
| ZA200706785B (en) | 2009-08-26 |
| RU2007128819A (ru) | 2009-03-27 |
| CA2596984A1 (en) | 2006-08-24 |
| PE20061092A1 (es) | 2006-12-05 |
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