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MX2007004740A - Derivados de 2-amido-4-feniltiazol, su preparacion y su aplicacion en terapeutica. - Google Patents

Derivados de 2-amido-4-feniltiazol, su preparacion y su aplicacion en terapeutica.

Info

Publication number
MX2007004740A
MX2007004740A MX2007004740A MX2007004740A MX2007004740A MX 2007004740 A MX2007004740 A MX 2007004740A MX 2007004740 A MX2007004740 A MX 2007004740A MX 2007004740 A MX2007004740 A MX 2007004740A MX 2007004740 A MX2007004740 A MX 2007004740A
Authority
MX
Mexico
Prior art keywords
amido
therapeutic use
preparation
phenylthiazole derivatives
general formula
Prior art date
Application number
MX2007004740A
Other languages
English (en)
Inventor
Pierre Casellas
Samir Jegham
Daniel Floutard
Pierre Fraisse
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of MX2007004740A publication Critical patent/MX2007004740A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La invencion tiene por objetos los derivados de 2-amido-4-feniltiazol, de la formula general (I) que sigue: (I) en el estado de base o de sal de adicion a un acido farmaceuticamente aceptable, en estado de hidratos o de solvatos, asi como en forma de enantiomeros, de diastereoisomeros y su mezcla. La invencion igualmente tiene por objeto composiciones farmaceuticas que contienen un compuesto de la formula general (I) y su aplicacion en terapeutica.
MX2007004740A 2004-10-19 2005-10-17 Derivados de 2-amido-4-feniltiazol, su preparacion y su aplicacion en terapeutica. MX2007004740A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0411083A FR2876692B1 (fr) 2004-10-19 2004-10-19 Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique
PCT/FR2005/002565 WO2006042954A1 (fr) 2004-10-19 2005-10-17 Dérivés de 2-amido-4-phenylthiazole, leur préparation et leur application en thérapeutique

Publications (1)

Publication Number Publication Date
MX2007004740A true MX2007004740A (es) 2007-06-18

Family

ID=34950743

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007004740A MX2007004740A (es) 2004-10-19 2005-10-17 Derivados de 2-amido-4-feniltiazol, su preparacion y su aplicacion en terapeutica.

Country Status (27)

Country Link
US (1) US7598392B2 (es)
EP (1) EP1807421B1 (es)
JP (1) JP2008517042A (es)
KR (1) KR20070085395A (es)
CN (1) CN101065376A (es)
AR (1) AR051334A1 (es)
AT (1) ATE502035T1 (es)
AU (1) AU2005296958A1 (es)
BR (1) BRPI0518231A2 (es)
CA (1) CA2584774A1 (es)
DE (1) DE602005026964D1 (es)
EA (1) EA200700901A1 (es)
EC (1) ECSP077402A (es)
FR (1) FR2876692B1 (es)
GT (1) GT200500292A (es)
IL (1) IL182624A0 (es)
MA (1) MA29017B1 (es)
MX (1) MX2007004740A (es)
NO (1) NO20072515L (es)
PA (1) PA8649901A1 (es)
PE (1) PE20060585A1 (es)
SV (1) SV2006002274A (es)
TN (1) TNSN07145A1 (es)
TW (1) TW200630364A (es)
UY (1) UY29169A1 (es)
WO (1) WO2006042954A1 (es)
ZA (1) ZA200703876B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2854158B1 (fr) 2003-04-25 2006-11-17 Sanofi Synthelabo Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique
FR2872813B1 (fr) 2004-07-09 2007-01-19 Sanofi Synthelabo Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique
TW200730476A (en) * 2005-12-12 2007-08-16 Genelabs Tech Inc N-(5-membered aromatic ring)-amido anti-viral compounds
FR2895989B1 (fr) 2006-01-06 2010-04-30 Sanofi Aventis Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique
WO2009076404A1 (en) * 2007-12-10 2009-06-18 Epix Delaware, Inc. Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor
EP2280766A1 (en) * 2007-12-11 2011-02-09 CytoPathfinder, Inc. Carboxamide compounds and their use as chemokine receptor agonists
PE20110105A1 (es) 2008-07-15 2011-02-25 Novartis Ag Derivados de heteroarilo como inhibidores de dgat1
EP4015504A1 (en) * 2008-12-22 2022-06-22 ChemoCentryx, Inc. C5ar antagonists
CN103402996B (zh) 2011-01-04 2015-02-11 诺瓦提斯公司 可用于治疗年龄相关性黄斑变性(amd)的吲哚化合物或其类似物
US9464081B2 (en) 2012-06-28 2016-10-11 Novartis Ag Pyrrolidine derivatives and their use as complement pathway modulators
EP2867225B1 (en) 2012-06-28 2017-08-09 Novartis AG Pyrrolidine derivatives and their use as complement pathway modulators
ES2710491T3 (es) 2012-06-28 2019-04-25 Novartis Ag Moduladores de la vía del complemento y sus usos
CN104640855B (zh) 2012-06-28 2017-08-29 诺华股份有限公司 补体途经调节剂及其用途
WO2014002053A1 (en) 2012-06-28 2014-01-03 Novartis Ag Pyrrolidine derivatives and their use as complement pathway modulators
CN104684910B (zh) 2012-07-12 2016-10-12 诺华股份有限公司 补体途经调节剂及其用途
MX2022010944A (es) 2020-03-03 2022-11-09 Pic Therapeutics Inc Inhibidores del factor de iniciacion de traduccion eucariotica 4e (eif4e) y sus usos.
WO2023028235A1 (en) 2021-08-25 2023-03-02 PIC Therapeutics, Inc. Eif4e inhibitors and uses thereof
CN118019739A (zh) 2021-08-25 2024-05-10 皮克医疗公司 Eif4e抑制剂及其用途
KR20240140019A (ko) * 2023-03-15 2024-09-24 현대약품 주식회사 신규한 화합물, 및 이를 포함하는 약학적 조성물

Family Cites Families (15)

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US2146898A (en) * 1937-12-06 1939-02-14 Int Harvester Co Potato digger
FR2406634A1 (fr) 1977-10-19 1979-05-18 Fabre Sa Pierre Immunostimulants derives d'amino thiazoles
FR2677356B1 (fr) 1991-06-05 1995-03-17 Sanofi Sa Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant.
EP0519449A1 (en) 1991-06-21 1992-12-23 Boehringer Mannheim Italia S.P.A. 2-Amino-4-aryl thiazoles with antiasthmatic and antiinflammatory activities on the respiratory tract
US6506751B1 (en) 1999-11-12 2003-01-14 Millennium Pharmaceuticals, Inc. Thiazolidinone compounds useful as chemokine inhibitors
US6852752B2 (en) * 1999-12-17 2005-02-08 Vicuron Pharmaceuticals Inc. Urea compounds, compositions and methods of use and preparation
US6797820B2 (en) * 1999-12-17 2004-09-28 Vicuron Pharmaceuticals Inc. Succinate compounds, compositions and methods of use and preparation
KR20030064852A (ko) 2000-12-22 2003-08-02 이시하라 산교 가부시끼가이샤 아닐린 유도체 또는 그의 염 및 이들을 함유하는사이토카인 생산 억제제
US7265134B2 (en) 2001-08-17 2007-09-04 Merck & Co., Inc. Tyrosine kinase inhibitors
TW200403058A (en) * 2002-04-19 2004-03-01 Bristol Myers Squibb Co Heterocyclo inhibitors of potassium channel function
FR2854158B1 (fr) * 2003-04-25 2006-11-17 Sanofi Synthelabo Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique
AR044098A1 (es) 2003-04-30 2005-08-24 Hoffmann La Roche Derivados de anilina, su elaboracion, composiciones farmaceuticas y su uso para elaborar medicamentos para el tratamiento del cancer
FR2872813B1 (fr) 2004-07-09 2007-01-19 Sanofi Synthelabo Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique
BRPI0519288A2 (pt) 2004-12-24 2009-01-06 Astrazeneca Ab compostos heterocÍclicos como antagonistas de ccr2b
FR2895989B1 (fr) 2006-01-06 2010-04-30 Sanofi Aventis Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
SV2006002274A (es) 2006-06-28
UY29169A1 (es) 2006-05-31
CA2584774A1 (fr) 2006-04-27
EP1807421A1 (fr) 2007-07-18
ECSP077402A (es) 2007-05-30
WO2006042954A8 (fr) 2008-03-13
US7598392B2 (en) 2009-10-06
MA29017B1 (fr) 2007-11-01
EP1807421B1 (fr) 2011-03-16
EA200700901A1 (ru) 2007-10-26
IL182624A0 (en) 2007-07-24
PE20060585A1 (es) 2006-08-18
WO2006042954A1 (fr) 2006-04-27
US20070259847A1 (en) 2007-11-08
CN101065376A (zh) 2007-10-31
NO20072515L (no) 2007-06-28
BRPI0518231A2 (pt) 2008-11-11
PA8649901A1 (es) 2006-06-02
AR051334A1 (es) 2007-01-03
FR2876692A1 (fr) 2006-04-21
AU2005296958A1 (en) 2006-04-27
JP2008517042A (ja) 2008-05-22
ATE502035T1 (de) 2011-04-15
DE602005026964D1 (de) 2011-04-28
KR20070085395A (ko) 2007-08-27
GT200500292A (es) 2006-05-11
ZA200703876B (en) 2008-12-31
TW200630364A (en) 2006-09-01
FR2876692B1 (fr) 2007-02-23
TNSN07145A1 (fr) 2008-11-21

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal