[go: up one dir, main page]

MX2007004321A - Micro acidos ribonucleicos. - Google Patents

Micro acidos ribonucleicos.

Info

Publication number
MX2007004321A
MX2007004321A MX2007004321A MX2007004321A MX2007004321A MX 2007004321 A MX2007004321 A MX 2007004321A MX 2007004321 A MX2007004321 A MX 2007004321A MX 2007004321 A MX2007004321 A MX 2007004321A MX 2007004321 A MX2007004321 A MX 2007004321A
Authority
MX
Mexico
Prior art keywords
target sequence
down regulation
micrornas
useful
regulaterna
Prior art date
Application number
MX2007004321A
Other languages
English (en)
Inventor
Nam-Hai Chua
Jose Reyes Toboda
Xiuren Zhang
Takashi Soyano
Qi-Wen Niu Niu
Shih-Shun Lin
Original Assignee
Univ Rockefeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rockefeller filed Critical Univ Rockefeller
Publication of MX2007004321A publication Critical patent/MX2007004321A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8262—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield involving plant development
    • C12N15/827—Flower development or morphology, e.g. flowering promoting factor [FPF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8283—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
    • C12N2310/141—MicroRNAs, miRNAs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Physiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

La invencion provee metodos y composiciones utiles en la supresion de secuencias de objetivo, validacion de secuencias de objetivo e hipo regulacion de secuencias de objetivo. La invencion provee constructos de polinucleotido utiles para silenciamiento de genes o hipo regulacion de ARN, asi como tambien celulas, plantas y semillas que comprenden los polinucleotidos. La invencion tambien provee un metodo para lautilizacion de microARN para silenciar una secuencia de objetivo o para hipo regular ARN.
MX2007004321A 2004-10-12 2005-10-12 Micro acidos ribonucleicos. MX2007004321A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
USPCT/US04/33379 2004-10-12
US67108905P 2005-04-14 2005-04-14
PCT/US2005/036373 WO2006044322A2 (en) 2004-10-12 2005-10-12 Micrornas

Publications (1)

Publication Number Publication Date
MX2007004321A true MX2007004321A (es) 2007-06-07

Family

ID=36203437

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007004321A MX2007004321A (es) 2004-10-12 2005-10-12 Micro acidos ribonucleicos.

Country Status (10)

Country Link
US (2) US8975471B2 (es)
EP (1) EP1809748B1 (es)
JP (1) JP2008522585A (es)
CN (1) CN101076592B (es)
AR (1) AR050972A1 (es)
AU (1) AU2005295948A1 (es)
BR (1) BRPI0516874A (es)
CA (1) CA2583690C (es)
MX (1) MX2007004321A (es)
WO (1) WO2006044322A2 (es)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2018431B1 (en) 2006-05-12 2011-08-10 Bayer BioScience N.V. Novel stress-related micro-RNA molecules and uses thereof
ES2655700T3 (es) 2006-08-31 2018-02-21 Monsanto Technology, Llc ARN pequeños en fase
US20080081330A1 (en) * 2006-09-28 2008-04-03 Helicos Biosciences Corporation Method and devices for analyzing small RNA molecules
WO2008074025A2 (en) * 2006-12-13 2008-06-19 Idiverse, Inc. Novel genes and rna molecules that confer stress tolerance
EP2099917B1 (en) 2007-01-11 2015-07-22 Bayer CropScience NV Differential expression of subgenome specific alleles in cotton and uses thereof
US20100125919A1 (en) * 2007-01-18 2010-05-20 Lionel Navarro Methods and compositions for modulating the mirna pathway
EP2115141A4 (en) * 2007-02-20 2010-08-04 Monsanto Technology Llc miRNA FROM INVERTEBRATES
WO2008143786A1 (en) * 2007-05-14 2008-11-27 The Rockefeller University Production of artificial micrornas using synthetic microrna precursors
AU2008260103B2 (en) 2007-05-31 2014-04-03 University Of Iowa Research Foundation Reduction of off-target RNA interference toxicity
EP2192925A4 (en) * 2007-08-23 2013-04-03 Keren Pharmaceuticals TARGETING RNA WITH EXTERNAL GUIDE SEQUENCES
US8115055B2 (en) * 2007-12-18 2012-02-14 E.I. Du Pont De Nemours And Company Down-regulation of gene expression using artificial microRNAs
EP2257628A4 (en) 2008-03-04 2011-11-02 Univ Washington State COMPOSITIONS AND METHODS FOR THE DIFFERENTIAL REGULATION OF THE INSETICITY OF FATTY ACIDS IN MEMBRANLIPIDES AND SEED OIL
CN104969864A (zh) 2008-05-26 2015-10-14 拜尔作物科学公司 改变产纤维植物中纤维强度的方法和手段
WO2010042575A1 (en) * 2008-10-08 2010-04-15 Monsanto Technology Llc Transgenic plants with enhanced agronomic traits
US8309530B2 (en) 2009-02-04 2012-11-13 Washington State University Compositions and methods for modulating ghrelin-mediated conditions
CN102803496A (zh) 2009-06-10 2012-11-28 淡马锡生命科学研究院有限公司 用于棉花中基因功能性分析的病毒诱导的基因沉默(vigs)
CN101710362B (zh) * 2009-12-10 2011-07-20 浙江大学 一种基于支持向量机的microRNA靶位点预测的方法
CN102985545A (zh) * 2010-06-30 2013-03-20 巴斯夫植物科学有限公司 新型微小rna前体及其在调控靶基因表达中的用途
CN101976296B (zh) * 2010-09-10 2012-05-23 浙江大学 结合基于下一代测序数据的植物microRNA靶位互作网络预测的方法
CN103270158A (zh) * 2010-10-15 2013-08-28 昆士兰大学 小的病毒rna分子及其用途
EP2673286B1 (en) 2011-02-12 2019-07-03 University of Iowa Research Foundation Therapeutic compounds
WO2012143805A1 (en) * 2011-04-21 2012-10-26 Basf Plant Science Company Gmbh Methods of modifying lignin biosynthesis and improving digestibility
ES2635115T3 (es) * 2012-01-23 2017-10-02 E. I. Du Pont De Nemours And Company Regulación por disminución de expresión génica utilizando micro ARN artificiales para silenciar genes biosintéticos de ácidos grasos
US10105351B2 (en) 2012-03-14 2018-10-23 University Of Central Florida Research Foundation, Inc. Neurofibromatoses therapeutic agents and screening for same
WO2013158032A1 (en) 2012-04-19 2013-10-24 Temasek Life Sciences Laboratory Limited Methods for increasing cotton fiber length
CN102703500B (zh) * 2012-05-30 2014-03-12 清华大学 利用植物病毒载体进行miRNA靶标模拟序列构建和表达的方法
US20140030792A1 (en) * 2012-07-23 2014-01-30 Radhakrishnan Rathnachalam Therapeutic Anti-Virus VLPS
US10190126B2 (en) * 2012-10-28 2019-01-29 A.B. Seeds Ltd. Transgenic plants with modified sugar content and methods of generating same
CN103088061B (zh) * 2013-01-15 2016-08-03 中国科学院微生物研究所 一种rna及载体在制备预防和/或治疗肝癌产品中的应用
US10612020B2 (en) 2013-12-26 2020-04-07 Tokyo Medical University Artificial mimic miRNA for controlling gene expression, and use of same
BR112016014986A2 (pt) * 2013-12-27 2018-01-23 Bonac Corporation mirna tipo correspondência artificial, composição e método para suprimir expressão de um gene alvo, composição farmacêutica, método para tratar uma doença, e, ácido nucleico de fita única
AU2015264263B2 (en) 2014-05-20 2021-08-05 University Of Iowa Research Foundation Huntington's disease therapeutic compounds
WO2016038511A1 (en) * 2014-09-10 2016-03-17 The New Zealand Institute For Plant And Food Research Limited Methods and materials for producing fruit of altered size
EP3206696A4 (en) * 2014-10-14 2018-08-08 Texas Tech University System Multiplexed shrnas and uses thereof
EP3209775A4 (en) 2014-10-22 2018-09-12 Temasek Life Sciences Laboratory Limited Terpene synthases from ylang ylang (cananga odorata var. fruticosa)
RU2740032C2 (ru) 2014-12-27 2020-12-30 Бонак Корпорейшн ВСТРЕЧАЮЩИЕСЯ В ПРИРОДЕ миРНК ДЛЯ КОНТРОЛИРОВАНИЯ ЭКСПРЕССИИ ГЕНОВ И ИХ ПРИМЕНЕНИЕ
CN104774837B (zh) * 2015-03-13 2018-02-02 浙江省医学科学院 9种植物微小核糖核苷酸及其应用
HK1244031A1 (en) 2015-03-27 2018-07-27 Bonac Corporation Single-chain nucleic acid molecule having delivery function and gene expression control ability
CN106167801B (zh) * 2016-09-30 2018-08-28 山东大学 大豆威廉姆斯82中NAC膜结合转录因子基因GmNTL1及其应用
WO2019103581A1 (ko) * 2017-11-27 2019-05-31 (주)프로스테믹스 이중 가닥의 올리고뉴클레오티드 및 그 제조 방법
CN111621588A (zh) * 2020-06-08 2020-09-04 华中农业大学 光亮果皮番茄品种选育的分子标记及其应用
CN112210555B (zh) * 2020-09-18 2022-02-22 大连理工大学 番茄抗晚疫病基因Sly-miR166b及其克隆方法与应用方法
CN114908089B (zh) * 2021-02-08 2024-03-15 上海细胞治疗集团有限公司 3’utr的构建方法和应用
CN114606236B (zh) * 2022-04-21 2024-01-05 南通大学 一种翘芪复方中药汤剂来源的微小核糖核酸及其制备方法和应用
CN115083516B (zh) * 2022-07-13 2023-03-21 北京先声医学检验实验室有限公司 一种基于靶向RNA测序技术检测基因融合的Panel设计和评估方法
CN117210463B (zh) * 2023-09-12 2024-03-19 扬州大学 一种与莲藕根状茎淀粉合成相关的miRNA及其应用
CN118516400B (zh) * 2024-07-24 2024-10-29 吉林农业大学 gma-miR169c基因在调控植物脂肪酸合成中的应用
CN120648688B (zh) * 2025-08-21 2025-11-07 中国农业科学院烟草研究所(中国烟草总公司青州烟草研究所) 与植物抗病毒相关的miR159a及其在提高植物对病毒抗性中的应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506559B1 (en) * 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
WO1999053050A1 (en) 1998-04-08 1999-10-21 Commonwealth Scientific And Industrial Research Organisation Methods and means for obtaining modified phenotypes
CA2386270A1 (en) * 1999-10-15 2001-04-26 University Of Massachusetts Rna interference pathway genes as tools for targeted genetic interference
WO2003070918A2 (en) 2002-02-20 2003-08-28 Ribozyme Pharmaceuticals, Incorporated Rna interference by modified short interfering nucleic acid
PT1309726E (pt) * 2000-03-30 2010-03-08 Whitehead Biomedical Inst Mediadores de interferência por rna específicos de sequência de rna
CA2453183C (en) 2001-07-12 2016-05-10 University Of Massachusetts In vivo production of small interfering rnas that mediate gene silencing
AU2002329667A1 (en) 2001-07-30 2003-02-17 Uta Griesenbach Specific inhibition of gene expression by small double stranded rnas
US7166771B2 (en) * 2002-06-21 2007-01-23 Monsanto Technology Llc Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs
ES2465574T3 (es) * 2002-05-03 2014-06-06 Duke University Un método para regular la expresión génica
BR0312580A (pt) * 2002-07-10 2006-10-10 Univ Kansas State composições e métodos para controlar nematódeos parasitas
WO2004009779A2 (en) * 2002-07-19 2004-01-29 University Of South Carolina Compositions and methods for the modulation of gene expression in plants
WO2004066183A2 (en) 2003-01-22 2004-08-05 European Molecular Biology Laboratory Microrna
US7750144B2 (en) * 2003-06-02 2010-07-06 University Of Massachusetts Methods and compositions for enhancing the efficacy and specificity of RNA silencing
WO2004111191A2 (en) * 2003-06-02 2004-12-23 University Of Massachusetts Methods and compositions for controlling efficacy of rna silencing
CA2527958C (en) * 2003-06-02 2014-04-08 University Of Massachusetts Methods and compositions for enhancing the efficacy and specificity of rnai
US20050144669A1 (en) * 2003-07-01 2005-06-30 Whitehead Institute For Biomedical Research MicroRNAs in plants
US7071380B1 (en) * 2003-08-29 2006-07-04 Agrigenesis Biosciences Limited Control of floral induction
CA2541914C (en) * 2003-10-09 2012-07-24 E.I. Du Pont De Nemours And Company Gene silencing by using micro-rna molecules

Also Published As

Publication number Publication date
WO2006044322A2 (en) 2006-04-27
CA2583690C (en) 2016-04-05
WO2006044322A3 (en) 2007-01-04
CN101076592B (zh) 2013-08-21
CN101076592A (zh) 2007-11-21
US8975471B2 (en) 2015-03-10
EP1809748B1 (en) 2012-12-26
JP2008522585A (ja) 2008-07-03
CA2583690A1 (en) 2006-04-27
AR050972A1 (es) 2006-12-06
US20060130176A1 (en) 2006-06-15
BRPI0516874A (pt) 2008-09-23
AU2005295948A1 (en) 2006-04-27
EP1809748A4 (en) 2009-03-25
US20150159157A1 (en) 2015-06-11
EP1809748A2 (en) 2007-07-25

Similar Documents

Publication Publication Date Title
MX2007004321A (es) Micro acidos ribonucleicos.
WO2005035769A3 (en) Gene silencing by using micro-rna molecules
MX2009003616A (es) Secuencias de microarn del maiz.
WO2005079397A3 (en) Anti-microrna oligonucleotide molecules
EP4170029A3 (en) Modifying the specifity of plant non-coding rna molecules for silencing gene expression
MY165006A (en) Method and compositions for producing fatty alcohols
WO2008091703A3 (en) Chemically modified oligonucleotides for use in modulating micro rna and uses thereof
WO2008133643A3 (en) Plant micrornas and methods of use thereof
WO2010042664A3 (en) Method and compositions for producing fatty aldehydes
WO2009006297A3 (en) Methods for altering the genome of a monocot plant cell
WO2006046148A3 (en) Rna constructs
UA103887C2 (ru) Способ получения стойкого к гербицидам растения
WO2007014275A3 (en) Targeted integration and expression of exogenous nucleic acid sequences
WO2008151058A3 (en) Methods of generating pluripotent cells from somatic cells
WO2005007196A3 (en) Lipid encapsulated interfering rna
WO2007095496A3 (en) Selecting and stabilizing dsrna constructs
WO2007021896A3 (en) Chemically modified oligonucleotides for use in modulating micro rna and uses thereof
WO2008061537A3 (en) Oligonucleotides for modulating target rna activity
WO2007146980A3 (en) Improved epsp synthases: compositions and methods of use
MX2009013064A (es) Composiciones y metodos de uso de la interferencia de arn para el control de nematodos.
WO2005112609A3 (en) Promotion of somatic embryogenesis in plants by pga37 gene expression
NZ595626A (en) Wood and cell wall gene microarray
WO2010022194A3 (en) Compositions and methods for generation of pluripotent stem cells
WO2007014075A3 (en) Rnai modulation of the rho-a gene in research models
GB2458419A (en) Vector for expressing NC protein of HIV and method for producing NC protein using the same

Legal Events

Date Code Title Description
FG Grant or registration