MEP12408A - Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptors - Google Patents

Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptors

Info

Publication number: MEP12408A
Authority: ME; Montenegro
Prior art keywords: ligands; receptors; acyloxypyrrolidine; derivatives; acyloxypyrrolidine derivatives
Prior art date: 2002-07-19

Application number

MEP-124/08A

Other languages

Bosnian (bs)

English (en)

Inventor

Alain Aulombard

Georges Garcia

Antoine Pradines

Gal Claudine Serradeil-Le

Jean Wagnon

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-19

Filing date

2003-07-17

Publication date

2010-06-10

2003-07-17 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2010-06-10 Publication of MEP12408A publication Critical patent/MEP12408A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Obesity (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Anesthesiology (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

MEP-124/08A 2002-07-19 2003-07-17 Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptors MEP12408A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0209242A FR2842527B1 (fr)	2002-07-19	2002-07-19	Derives d'acyloxypyrolidine, leur preparation et leur application en therapeutique
PCT/FR2003/002262 WO2004009585A2 (fr)	2002-07-19	2003-07-17	Derives d'acyloxypyrrolidine et leur utilisation en tant que ligands des recepteurs v1b et v1a de avp

Publications (1)

Publication Number	Publication Date
MEP12408A true MEP12408A (en)	2010-06-10

Family

ID=29797610

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MEP-124/08A MEP12408A (en)	2002-07-19	2003-07-17	Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptors

Country Status (27)

Country	Link
US (1)	US7202267B2 (zh)
EP (1)	EP1525198B1 (zh)
JP (1)	JP4264414B2 (zh)
CN (1)	CN100425608C (zh)
AR (1)	AR040571A1 (zh)
AT (1)	ATE312092T1 (zh)
AU (1)	AU2003271815B8 (zh)
BR (1)	BR0312800A (zh)
CA (1)	CA2492224A1 (zh)
DE (1)	DE60302670T2 (zh)
DK (1)	DK1525198T3 (zh)
EA (1)	EA008444B1 (zh)
ES (1)	ES2254962T3 (zh)
FR (1)	FR2842527B1 (zh)
HR (1)	HRP20041231A2 (zh)
IL (1)	IL165942A (zh)
IS (1)	IS2487B (zh)
ME (1)	MEP12408A (zh)
MX (1)	MXPA05000822A (zh)
NO (1)	NO20050292L (zh)
NZ (1)	NZ537615A (zh)
PL (1)	PL375309A1 (zh)
RS (1)	RS20050018A (zh)
TW (1)	TWI274751B (zh)
UA (1)	UA78805C2 (zh)
WO (1)	WO2004009585A2 (zh)
ZA (1)	ZA200500478B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1659121A4 (en)	2003-08-28	2008-11-26	Taisho Pharmaceutical Co Ltd	1,3-dihydro-2H-indol-2-one derivative
TW200643015A (en)	2005-03-11	2006-12-16	Akzo Nobel Nv	2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives
DE102005015957A1 (de) *	2005-03-31	2006-10-05	Abbott Gmbh & Co. Kg	Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
CA2610400A1 (en)	2005-06-07	2006-12-14	Pharmacopeia, Inc.	Azinone and diazinone v3 inhibitors for depression and stress disorders
EP2069315B1 (en)	2006-09-11	2011-09-07	N.V. Organon	Quinazolinone and isoquinolinone acetamide derivatives
CN103864658B (zh) *	2014-03-06	2016-06-15	南京工业大学	氮杂环丁酮衍生物及其制备方法与应用
CN104447489B (zh) *	2014-12-29	2017-01-11	南京工业大学	3,4-二芳基马来酰亚胺衍生物及其制备方法与应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2804114B1 (fr) *	2000-01-25	2002-03-08	Sanofi Synthelabo	Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant

2002
- 2002-07-19 FR FR0209242A patent/FR2842527B1/fr not_active Expired - Fee Related
2003
- 2003-07-15 AR AR20030102539A patent/AR040571A1/es unknown
- 2003-07-17 UA UAA200500286A patent/UA78805C2/uk unknown
- 2003-07-17 JP JP2004522252A patent/JP4264414B2/ja not_active Expired - Fee Related
- 2003-07-17 PL PL03375309A patent/PL375309A1/xx not_active IP Right Cessation
- 2003-07-17 EP EP03753652A patent/EP1525198B1/fr not_active Expired - Lifetime
- 2003-07-17 EA EA200500032A patent/EA008444B1/ru not_active IP Right Cessation
- 2003-07-17 CA CA002492224A patent/CA2492224A1/en not_active Abandoned
- 2003-07-17 MX MXPA05000822A patent/MXPA05000822A/es active IP Right Grant
- 2003-07-17 BR BR0312800-8A patent/BR0312800A/pt not_active IP Right Cessation
- 2003-07-17 ES ES03753652T patent/ES2254962T3/es not_active Expired - Lifetime
- 2003-07-17 DE DE60302670T patent/DE60302670T2/de not_active Expired - Lifetime
- 2003-07-17 AU AU2003271815A patent/AU2003271815B8/en not_active Ceased
- 2003-07-17 DK DK03753652T patent/DK1525198T3/da active
- 2003-07-17 AT AT03753652T patent/ATE312092T1/de active
- 2003-07-17 ME MEP-124/08A patent/MEP12408A/xx unknown
- 2003-07-17 HR HR20041231A patent/HRP20041231A2/hr not_active Application Discontinuation
- 2003-07-17 RS YUP-2005/0018A patent/RS20050018A/sr unknown
- 2003-07-17 WO PCT/FR2003/002262 patent/WO2004009585A2/fr not_active Ceased
- 2003-07-17 CN CNB038218178A patent/CN100425608C/zh not_active Expired - Fee Related
- 2003-07-17 NZ NZ537615A patent/NZ537615A/en not_active IP Right Cessation
- 2003-07-18 TW TW092119736A patent/TWI274751B/zh not_active IP Right Cessation
2004
- 2004-12-22 IL IL165942A patent/IL165942A/en not_active IP Right Cessation
2005
- 2005-01-12 IS IS7641A patent/IS2487B/is unknown
- 2005-01-18 ZA ZA200500478A patent/ZA200500478B/xx unknown
- 2005-01-19 NO NO20050292A patent/NO20050292L/no not_active Application Discontinuation
- 2005-01-19 US US11/038,384 patent/US7202267B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP4264414B2 (ja)	2009-05-20
BR0312800A (pt)	2005-04-19
AU2003271815A1 (en)	2004-02-09
AU2003271815B2 (en)	2009-03-12
WO2004009585A3 (fr)	2004-05-06
WO2004009585A2 (fr)	2004-01-29
EP1525198A2 (fr)	2005-04-27
DK1525198T3 (da)	2006-04-18
US7202267B2 (en)	2007-04-10
HRP20041231A2 (en)	2005-02-28
PL375309A1 (en)	2005-11-28
IS2487B (is)	2008-12-15
DE60302670T2 (de)	2006-09-07
RS20050018A (sr)	2007-06-04
JP2005537271A (ja)	2005-12-08
AU2003271815B8 (en)	2009-04-30
ATE312092T1 (de)	2005-12-15
MXPA05000822A (es)	2005-08-29
IS7641A (is)	2005-01-12
UA78805C2 (en)	2007-04-25
EP1525198B1 (fr)	2005-12-07
AR040571A1 (es)	2005-04-13
TWI274751B (en)	2007-03-01
HK1074444A1 (zh)	2005-11-11
CN100425608C (zh)	2008-10-15
IL165942A (en)	2010-04-15
NO20050292L (no)	2005-04-19
US20050192335A1 (en)	2005-09-01
FR2842527A1 (fr)	2004-01-23
CA2492224A1 (en)	2004-01-29
CN1681806A (zh)	2005-10-12
IL165942A0 (en)	2006-01-15
TW200410957A (en)	2004-07-01
EA008444B1 (ru)	2007-06-29
ES2254962T3 (es)	2006-06-16
EA200500032A1 (ru)	2005-08-25
NZ537615A (en)	2006-11-30
FR2842527B1 (fr)	2005-01-28
DE60302670D1 (de)	2006-01-12
ZA200500478B (en)	2006-07-26

Publication	Publication Date	Title
ATE233256T1 (de)	2003-03-15	2-pyrimidinamin derivaten und verfahrens zu deren herstellung
AR034792A1 (es)	2004-03-17	Derivados de 1-fenilsulfonil-1,3-dihidro-2h-indol-2-ona, su preparacion y su aplicacion en terapeutica
DK0794949T3 (da)	1999-05-03	Hidtil ukendte 3,5-dioxo-(2H,4H)-1,2,4-triazinderivater, fremstilling heraf og deres anvendelse som lægemidler
DK1074542T3 (da)	2006-08-14	Sulfonamidholdige indolforbindelser
HRP20070203T3 (hr)	2007-06-30	Derivati n-[fenil(alkilpiperidin-2-il)metil]benzamida, njihovo dobivanje i njihova primjena u terapiji
HRP20090162T1 (en)	2009-05-31	Quinolinone-carboxamide compounds as 5-ht4 receptor agonists
HRP20040429B1 (hr)	2007-10-31	Derivati sulfonamida, njihova priprema i upotrebakao lijekova
DE60033964D1 (de)	2007-04-26	Phenoxypropanolamin-derivate, ihre herstellung und therapeutische verwendung
NO20071008L (no)	2007-02-21	Fremgangsmate for fremstilling av N-piperidino-1,5-difenylpyrazol-3-karboksamidderivater
DK0918776T3 (da)	2004-07-12	Totalsyntese af antitumor acylfulvener
DE3876813D1 (de)	1993-02-04	3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a.
ATE503746T1 (de)	2011-04-15	Neue imidazolidinderivate
DK1447400T3 (da)	2008-12-08	Bicyklisk forbindelse
DK0784055T3 (da)	2003-06-02	Pyrimidinylpyrazolderivater
MEP12408A (en)	2010-06-10	Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptors
NO971142L (no)	1997-03-12	Bis-(2-halogenetyl)aminofenylsubstituerte distamycinderivater som antitumor- og antivirale midler
NZ221699A (en)	1990-03-27	Pyridazinone derivatives; pharmaceutical compositions and intermediates
TW200607808A (en)	2006-03-01	Pyrido-pyrimidine derivatives, preparation thereof and application thereof
IS6452A (is)	2002-06-28	Ný tetrahýdrópýridín, framleiðsluaðferð og lyfjasamsetningar sem innihalda þau
ATE215555T1 (de)	2002-04-15	17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose
NO20041704L (no)	2004-04-26	Substituerte alkylaminopyridazinonderivater, fremgangsmater for deres fremstilling og farmasoytiske sammensetninger som inneholder disse
ATE250597T1 (de)	2003-10-15	N-benzolsulfonyl-l-prolin derivate, verfahren zu ihrer herstellung und ihre therapeutische verwendung
YU78001A (sh)	2004-07-15	Derivati 6-(((aril i heteroaril)oksi)metil) naftalen-2- karboksimidamida, njihovo dobijanje i terapeutska primena
DK0782574T3 (da)	2002-05-06	Bicycliske carboxiamider som 5-HT1A-receptorligander
DE60221250D1 (de)	2007-08-30	Bis(5-aryl-2-pyridyl)derivate