NO20041704L - Substituerte alkylaminopyridazinonderivater, fremgangsmater for deres fremstilling og farmasoytiske sammensetninger som inneholder disse - Google Patents

Substituerte alkylaminopyridazinonderivater, fremgangsmater for deres fremstilling og farmasoytiske sammensetninger som inneholder disse

Info

Publication number: NO20041704L
Authority: NO; Norway
Prior art keywords: sub; hydrogen; stands; alkyl; carbon atoms
Prior art date: 2001-09-27

Application number

NO20041704A

Other languages

English (en)

Other versions

NO325080B1 (no

Inventor

Aniko Miklosne Kovacs

Istvan Gacsalyi

Jozsef Barkoczy

Janos Wellmann

Laszlo Gabor Harsing

Peter Kotay Nagy

Gyorgy Levay

Andras Egyed

Gyula Simig

Eva Schmidt

Gabor Szenasi

Bernadett Martonne Marko

Csilla Leveleki

Hajnalka Kompagne

Original Assignee

Egyt Gyogyszervegyeszeti Gyar

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-27

Filing date

2004-04-26

Publication date

2004-04-26

2004-04-26 Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar

2004-04-26 Publication of NO20041704L publication Critical patent/NO20041704L/no

2008-01-28 Publication of NO325080B1 publication Critical patent/NO325080B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO20041704A 2001-09-27 2004-04-26 Substituerte alkylaminopyridazinonderivater, fremgangsmater til deres fremstilling, og farmasoytiske sammensetninger som inneholder disse, fremgangsmate til fremstilling av sammensetningen og anvendelse av derivatene til a fremstille farmasoytiske preparater. NO325080B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU0103912A HU227237B1 (en)	2001-09-27	2001-09-27	Substituted alkylpyridazinone derivatives, process for their preparation, pharmaceutical compositions containing them
PCT/HU2002/000096 WO2003027097A1 (en)	2001-09-27	2002-09-26	Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same

Publications (2)

Publication Number	Publication Date
NO20041704L true NO20041704L (no)	2004-04-26
NO325080B1 NO325080B1 (no)	2008-01-28

Family

ID=89979721

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO20041551A NO326370B1 (no)	2001-09-27	2004-04-16	Substituerte alkylaminopyridazinonderivater, fremgangsmate til fremstilling derav, anvendelse derav, farmasoytisk sammensetning som inneholder dem og fremgangsmate for fremstilling av sammensetningene
NO20041704A NO325080B1 (no)	2001-09-27	2004-04-26	Substituerte alkylaminopyridazinonderivater, fremgangsmater til deres fremstilling, og farmasoytiske sammensetninger som inneholder disse, fremgangsmate til fremstilling av sammensetningen og anvendelse av derivatene til a fremstille farmasoytiske preparater.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
NO20041551A NO326370B1 (no)	2001-09-27	2004-04-16	Substituerte alkylaminopyridazinonderivater, fremgangsmate til fremstilling derav, anvendelse derav, farmasoytisk sammensetning som inneholder dem og fremgangsmate for fremstilling av sammensetningene

Country Status (25)

Country	Link
US (2)	US6930110B2 (no)
EP (2)	EP1430047B1 (no)
JP (2)	JP2005508914A (no)
KR (2)	KR100911069B1 (no)
CN (3)	CN100368404C (no)
AT (2)	ATE288899T1 (no)
AU (2)	AU2002328166B2 (no)
BR (2)	BR0212932A (no)
CA (2)	CA2461510C (no)
CZ (2)	CZ2004528A3 (no)
DE (2)	DE60202970T2 (no)
DK (2)	DK1430034T3 (no)
EA (2)	EA006392B1 (no)
ES (2)	ES2237696T3 (no)
HU (1)	HU227237B1 (no)
MA (2)	MA27068A1 (no)
MX (2)	MXPA04002838A (no)
NO (2)	NO326370B1 (no)
NZ (2)	NZ532103A (no)
PL (2)	PL369256A1 (no)
PT (2)	PT1430034E (no)
SI (2)	SI1430047T1 (no)
SK (2)	SK1892004A3 (no)
WO (2)	WO2003027097A1 (no)
ZA (2)	ZA200402545B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1408976B3 (en) *	2001-07-20	2010-08-25	Psychogenics Inc.	Treatment for attention-deficit hyperactivity disorder
HU227592B1 (en) *	2002-11-13	2011-09-28	Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag	Use of substituted alkyl-piridazinone derivatives for the treatment of memory decline and learning malfunctions
EP2137179B1 (en) *	2007-03-15	2015-09-02	Merck Sharp & Dohme Corp.	Pyridazinone derivatives useful as glucan synthase inhibitors
CN120987912A (zh) *	2018-04-30	2025-11-21	内尔维亚诺医药科学有限公司	作为parp7抑制剂的哒嗪酮
CN109053693B (zh)	2018-09-20	2021-02-05	顺毅股份有限公司	哒嗪胺类化合物的制备及其应用
US12371421B2 (en)	2019-04-29	2025-07-29	Ribon Therapeutics, Inc.	Solid forms of a PARP7 inhibitor
WO2022188889A1 (zh) *	2021-03-12	2022-09-15	杭州英创医药科技有限公司	作为parp7抑制剂的化合物
CN115490671B (zh) *	2022-10-21	2024-05-14	水木未来(北京)科技有限公司	Parp7抑制剂及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH557820A (de) *	1970-11-12	1975-01-15	Sandoz Ag	Verfahren zur herstellung von neuen 2-(2-hydroxyalkyl)4,5-dihydro-pyridazin (2h)-3-onen.
IE62890B1 (en) *	1988-12-06	1995-03-08	Hafslund Nycomed Pharma	New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure
PL164079B1 (pl)	1990-06-15	1994-06-30	Akad Medyczna	posób wytwarzania nowych 2-amlnoalkilopochodnych 5-aminometyleno-6-/p-chlorofenylo /-4,5-dihydro-2H- plrydazyn -3-onu
HU209388B (en) *	1990-12-27	1994-05-30	Richter Gedeon Vegyeszet	Process for producing new 3/2h/-pyridazinones and pharmaceutical compositions comprising same
HU214320B (hu) *	1991-12-20	1998-03-02	EGIS Gyógyszergyár Rt.	Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására
HU224067B1 (hu)	1995-05-29	2005-05-30	Gyógyszerkutató Intézet Kft.	3(2H)-Piridazinon-származékok és e vegyületeket tartalmazó gyógyszerkészítmények
AU752967B2 (en) *	1998-06-05	2002-10-03	Egis Gyogyszergyar Rt.	Process for the preparation of a 3(2H)-pyridazinone- 4-substituted amino- 5-chloro- derivative

2001
- 2001-09-27 HU HU0103912A patent/HU227237B1/hu not_active IP Right Cessation
2002
- 2002-09-26 AT AT02767729T patent/ATE288899T1/de not_active IP Right Cessation
- 2002-09-26 SK SK1892004A patent/SK1892004A3/sk unknown
- 2002-09-26 AU AU2002328166A patent/AU2002328166B2/en not_active Ceased
- 2002-09-26 NZ NZ532103A patent/NZ532103A/en unknown
- 2002-09-26 CZ CZ2004528A patent/CZ2004528A3/cs unknown
- 2002-09-26 PT PT02767729T patent/PT1430034E/pt unknown
- 2002-09-26 AU AU2002330656A patent/AU2002330656B9/en not_active Ceased
- 2002-09-26 MX MXPA04002838A patent/MXPA04002838A/es active IP Right Grant
- 2002-09-26 US US10/491,151 patent/US6930110B2/en not_active Expired - Fee Related
- 2002-09-26 EA EA200400469A patent/EA006392B1/ru not_active IP Right Cessation
- 2002-09-26 CN CNB028189752A patent/CN100368404C/zh not_active Expired - Fee Related
- 2002-09-26 PL PL02369256A patent/PL369256A1/xx unknown
- 2002-09-26 BR BR0212932-9A patent/BR0212932A/pt not_active IP Right Cessation
- 2002-09-26 EP EP02762620A patent/EP1430047B1/en not_active Expired - Lifetime
- 2002-09-26 CA CA002461510A patent/CA2461510C/en not_active Expired - Fee Related
- 2002-09-26 MX MXPA04002836A patent/MXPA04002836A/es active IP Right Grant
- 2002-09-26 DK DK02767729T patent/DK1430034T3/da active
- 2002-09-26 BR BR0212839-0A patent/BR0212839A/pt not_active IP Right Cessation
- 2002-09-26 EA EA200400470A patent/EA006942B1/ru not_active IP Right Cessation
- 2002-09-26 CZ CZ2004532A patent/CZ2004532A3/cs unknown
- 2002-09-26 PL PL02369107A patent/PL369107A1/xx not_active IP Right Cessation
- 2002-09-26 DK DK02762620T patent/DK1430047T3/da active
- 2002-09-26 ES ES02767729T patent/ES2237696T3/es not_active Expired - Lifetime
- 2002-09-26 SK SK1902004A patent/SK1902004A3/sk unknown
- 2002-09-26 AT AT02762620T patent/ATE288910T1/de not_active IP Right Cessation
- 2002-09-26 KR KR1020047004607A patent/KR100911069B1/ko not_active Expired - Fee Related
- 2002-09-26 US US10/490,959 patent/US20050043314A1/en not_active Abandoned
- 2002-09-26 KR KR1020047004606A patent/KR100890667B1/ko not_active Expired - Fee Related
- 2002-09-26 CN CN200710104934XA patent/CN101099740B/zh not_active Expired - Fee Related
- 2002-09-26 WO PCT/HU2002/000096 patent/WO2003027097A1/en not_active Ceased
- 2002-09-26 WO PCT/HU2002/000097 patent/WO2003027078A1/en not_active Ceased
- 2002-09-26 DE DE60202970T patent/DE60202970T2/de not_active Expired - Lifetime
- 2002-09-26 DE DE60202969T patent/DE60202969T2/de not_active Expired - Lifetime
- 2002-09-26 SI SI200230109T patent/SI1430047T1/xx unknown
- 2002-09-26 CN CNB028204425A patent/CN1325489C/zh not_active Expired - Fee Related
- 2002-09-26 CA CA002461467A patent/CA2461467A1/en not_active Abandoned
- 2002-09-26 PT PT02762620T patent/PT1430047E/pt unknown
- 2002-09-26 SI SI200230107T patent/SI1430034T1/xx unknown
- 2002-09-26 EP EP02767729A patent/EP1430034B1/en not_active Expired - Lifetime
- 2002-09-26 JP JP2003530669A patent/JP2005508914A/ja active Pending
- 2002-09-26 ES ES02762620T patent/ES2237690T3/es not_active Expired - Lifetime
- 2002-09-26 NZ NZ532104A patent/NZ532104A/en unknown
- 2002-09-26 JP JP2003530685A patent/JP4472337B2/ja not_active Expired - Lifetime
2004
- 2004-03-24 MA MA27589A patent/MA27068A1/fr unknown
- 2004-03-24 MA MA27588A patent/MA27137A1/fr unknown
- 2004-03-31 ZA ZA200402545A patent/ZA200402545B/en unknown
- 2004-03-31 ZA ZA200402544A patent/ZA200402544B/en unknown
- 2004-04-16 NO NO20041551A patent/NO326370B1/no not_active IP Right Cessation
- 2004-04-26 NO NO20041704A patent/NO325080B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN101099740B (zh)	2010-09-08
EA006392B1 (ru)	2005-12-29
ZA200402544B (en)	2005-04-26
HK1069817A1 (en)	2005-06-03
JP2005503437A (ja)	2005-02-03
DE60202969D1 (de)	2005-03-17
HU0103912D0 (en)	2001-12-28
EP1430034A1 (en)	2004-06-23
DE60202970T2 (de)	2006-02-16
EA200400469A1 (ru)	2004-08-26
PT1430047E (pt)	2005-06-30
ZA200402545B (en)	2005-04-26
MXPA04002838A (es)	2004-07-05
MA27137A1 (fr)	2005-01-03
CN101099740A (zh)	2008-01-09
MXPA04002836A (es)	2004-07-05
KR100911069B1 (ko)	2009-08-06
HK1115728A1 (en)	2008-12-05
KR100890667B1 (ko)	2009-03-26
HK1069816A1 (en)	2005-06-03
NO325080B1 (no)	2008-01-28
HU227237B1 (en)	2010-12-28
CA2461510A1 (en)	2003-04-03
PL369256A1 (en)	2005-04-18
CZ2004532A3 (cs)	2004-08-18
AU2002330656A2 (en)	2003-04-07
CZ2004528A3 (cs)	2004-08-18
US20050043314A1 (en)	2005-02-24
AU2002330656B2 (en)	2009-04-09
ATE288910T1 (de)	2005-02-15
WO2003027078A1 (en)	2003-04-03
SI1430047T1 (en)	2005-08-31
MA27068A1 (fr)	2004-12-20
AU2002328166B2 (en)	2008-04-17
NZ532103A (en)	2005-08-26
SI1430034T1 (en)	2005-08-31
AU2002330656B9 (en)	2009-09-03
CA2461467A1 (en)	2003-04-03
EA200400470A1 (ru)	2004-08-26
ES2237696T3 (es)	2005-08-01
HUP0103912A3 (en)	2004-03-01
US6930110B2 (en)	2005-08-16
JP4472337B2 (ja)	2010-06-02
JP2005508914A (ja)	2005-04-07
NZ532104A (en)	2005-10-28
PT1430034E (pt)	2005-06-30
EP1430047B1 (en)	2005-02-09
ES2237690T3 (es)	2005-08-01
PL369107A1 (en)	2005-04-18
DK1430034T3 (da)	2005-05-30
AU2002328166A2 (en)	2003-04-07
CN1558904A (zh)	2004-12-29
DE60202969T2 (de)	2006-01-19
BR0212839A (pt)	2004-10-13
US20040242873A1 (en)	2004-12-02
EA006942B1 (ru)	2006-06-30
ATE288899T1 (de)	2005-02-15
EP1430047A1 (en)	2004-06-23
KR20040039446A (ko)	2004-05-10
SK1902004A3 (en)	2004-10-05
DE60202970D1 (de)	2005-03-17
KR20040039445A (ko)	2004-05-10
HUP0103912A2 (hu)	2003-07-28
BR0212932A (pt)	2004-10-13
DK1430047T3 (da)	2005-06-06
CN100368404C (zh)	2008-02-13
SK1892004A3 (en)	2004-10-05
CA2461510C (en)	2009-07-07
WO2003027097A1 (en)	2003-04-03
NO20041551L (no)	2004-06-10
CN1325489C (zh)	2007-07-11
CN1571783A (zh)	2005-01-26
NO326370B1 (no)	2008-11-17
EP1430034B1 (en)	2005-02-09

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HUP0100615A2 (hu)	2001-10-28	Szubsztituált 2-(2,6-dioxo-3-fluoro-piperidin-3-il)-izoindolinok és ezek alkalmazása TNFalfa-szint csökkentésére
HRP20040317A2 (en)	2006-06-30	1,8-naphthyridine derivatives as antidiabetics
ATE505462T1 (de)	2011-04-15	Neue biologischaktive molekü le
NO20041704L (no)	2004-04-26	Substituerte alkylaminopyridazinonderivater, fremgangsmater for deres fremstilling og farmasoytiske sammensetninger som inneholder disse
GB0223232D0 (en)	2002-11-13	Chemical compounds
TW200607808A (en)	2006-03-01	Pyrido-pyrimidine derivatives, preparation thereof and application thereof
AP1396A (en)	2005-04-19	1-Trifluoromethyl-4-hydroxy-7-piperidinylaminomethylchroman derivatives.
MXPA04003741A (es)	2004-07-23	Derivados novedosos de hidroxialquil indolocarbazol, metodo de preparacion y composiciones farmaceuticas que los contienen.
PL371520A1 (en)	2005-06-27	New piperidinyl-alkylamino-pyridazinone derivatives, a process for the preparation thereof and pharmaceutical compositions containing said compounds
HUP0302258A2 (hu)	2003-11-28	Fenoxifenil-alkánszulfonátok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
IS7034A (is)	2003-11-13	Díhýdróimidazó [5,1-A-] -SG(b)-karbólínafleiður, aðferð til framleiðslu þeirra og notkun sem lyf
DE60239324D1 (de)	2011-04-14	Phenyl- und pyridyl-piperidine mit tnf-wirkung
GB0223234D0 (en)	2002-11-13	Chemical compounds
EA200100156A3 (ru)	2001-10-22	Новые производные 6-сульфамоил-3-хинолилфосфоновой кислоты, способ их получения и содержащие их фармацевтические композиции
SE0100344D0 (sv)	2001-02-05	New Use

Legal Events

Date	Code	Title	Description
2010-04-26	MM1K	Lapsed by not paying the annual fees