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ME01914B - Derivati 3,4,4a,10b-tetrahidro-1h-tiopirano-[4,3-c]izohinolina - Google Patents

Derivati 3,4,4a,10b-tetrahidro-1h-tiopirano-[4,3-c]izohinolina

Info

Publication number
ME01914B
ME01914B MEP-2014-114A MEP11414A ME01914B ME 01914 B ME01914 B ME 01914B ME P11414 A MEP11414 A ME P11414A ME 01914 B ME01914 B ME 01914B
Authority
ME
Montenegro
Prior art keywords
tiopirano
izohinolina
derivati
test
Prior art date
Application number
MEP-2014-114A
Other languages
English (en)
Inventor
Degenhard Marx
Clemens Braun
Dieter Flockerzi
Thomas Stengel
Alexander Mann
Harald Ohmer
Ulrich Kautz
Steffen Weinbrenner
Stefan Fischer
Christof Zitt
Armin Hatzelmann
Torsten Dunkern
Christian Hesslinger
Thomas Maier
Hermann Tenor
Raimund Külzer
Original Assignee
Takeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Gmbh filed Critical Takeda Gmbh
Publication of ME01914B publication Critical patent/ME01914B/me

Links

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
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    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
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    • A61P9/12Antihypertensives

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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
MEP-2014-114A 2009-12-18 2010-12-15 Derivati 3,4,4a,10b-tetrahidro-1h-tiopirano-[4,3-c]izohinolina ME01914B (me)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP09179982 2009-12-18
US31555210P 2010-03-19 2010-03-19
EP10790569.7A EP2513119B1 (en) 2009-12-18 2010-12-15 3,4,4a,10b-tetrahydro-1h-thiopyrano-[4,3-c]isoquinoline derivatives
PCT/EP2010/069704 WO2011073231A1 (en) 2009-12-18 2010-12-15 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4, 3-c] ISOQUINOLINE DERIVATIVES

Publications (1)

Publication Number Publication Date
ME01914B true ME01914B (me) 2015-05-20

Family

ID=41718903

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2014-114A ME01914B (me) 2009-12-18 2010-12-15 Derivati 3,4,4a,10b-tetrahidro-1h-tiopirano-[4,3-c]izohinolina

Country Status (29)

Country Link
US (1) US9018175B2 (me)
EP (2) EP2513119B1 (me)
JP (1) JP5645961B2 (me)
KR (1) KR20120123313A (me)
CN (1) CN102652136B (me)
AR (1) AR079451A1 (me)
AU (1) AU2010332955B8 (me)
BR (1) BR112012014058A8 (me)
CA (1) CA2784013A1 (me)
CO (1) CO6551705A2 (me)
DK (1) DK2513119T3 (me)
EA (1) EA023212B1 (me)
ES (2) ES2505290T3 (me)
GE (1) GEP20146105B (me)
HR (1) HRP20140893T1 (me)
ME (1) ME01914B (me)
MX (1) MX2012006696A (me)
NZ (1) NZ601115A (me)
PH (1) PH12012501125A1 (me)
PL (1) PL2513119T3 (me)
PT (1) PT2513119E (me)
RS (1) RS53544B1 (me)
SG (2) SG180824A1 (me)
SI (1) SI2513119T1 (me)
SM (1) SMT201400185B (me)
TW (1) TWI468411B (me)
UA (1) UA107689C2 (me)
WO (1) WO2011073231A1 (me)
ZA (1) ZA201204135B (me)

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