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MD4349C1 - Соединение N-(3-метоксифенил)-2-(пиридин-2-илметилен)-гидразинкарботиоамид - ингибитор пролиферации клеток MeW-164 меланомы человека - Google Patents

Соединение N-(3-метоксифенил)-2-(пиридин-2-илметилен)-гидразинкарботиоамид - ингибитор пролиферации клеток MeW-164 меланомы человека Download PDF

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Publication number
MD4349C1
MD4349C1 MDA20140062A MD20140062A MD4349C1 MD 4349 C1 MD4349 C1 MD 4349C1 MD A20140062 A MDA20140062 A MD A20140062A MD 20140062 A MD20140062 A MD 20140062A MD 4349 C1 MD4349 C1 MD 4349C1
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Moldova
Prior art keywords
human melanoma
ylmethylene
mew
methoxyphenyl
compound
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MDA20140062A
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English (en)
Romanian (ro)
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MD4349B1 (ru
Inventor
Аурелиан ГУЛЯ
Анджей ЛИПКОВСКИЙ
Ольга ГАРБУЗ
Джоанна МАТАЛИНСКА
Виктор ЦАПКОВ
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Государственный Университет Молд0
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Priority to MDA20140062A priority Critical patent/MD4349C1/ru
Publication of MD4349B1 publication Critical patent/MD4349B1/ru
Publication of MD4349C1 publication Critical patent/MD4349C1/ru

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Изобретение относится к химии и медицине, а именно к органическому соединению класса тиоамидов, который может найти применение в медицине в качестве цитостатика для профилактики и лечения меланомы человека.Сущность изобретения заключается в синтезе соединения N-(3-метоксифенил)-2-(пиридин-2-илметилен)-гидразинкарботиоамида формулы:,который проявляет свойство ингибирования пролиферации клеток MeW-164меланомы человека.
MDA20140062A 2014-06-23 2014-06-23 Соединение N-(3-метоксифенил)-2-(пиридин-2-илметилен)-гидразинкарботиоамид - ингибитор пролиферации клеток MeW-164 меланомы человека MD4349C1 (ru)

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MDA20140062A MD4349C1 (ru) 2014-06-23 2014-06-23 Соединение N-(3-метоксифенил)-2-(пиридин-2-илметилен)-гидразинкарботиоамид - ингибитор пролиферации клеток MeW-164 меланомы человека

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MDA20140062A MD4349C1 (ru) 2014-06-23 2014-06-23 Соединение N-(3-метоксифенил)-2-(пиридин-2-илметилен)-гидразинкарботиоамид - ингибитор пролиферации клеток MeW-164 меланомы человека

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MD4349B1 MD4349B1 (ru) 2015-05-31
MD4349C1 true MD4349C1 (ru) 2015-12-31

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4520C1 (ru) * 2016-12-16 2018-05-31 Государственный Университет Молд0 N-(4-бутоксифенил)-2-(пиридин-2-илметилиден)гидразинкарботиоамид в качестве ингибитора роста клеток T-47D рака молочной железы

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CN101260121A (zh) * 2007-03-07 2008-09-10 卡南吉医药科技（上海）有限公司 杂芳环缩氨基硫脲与过渡金属的络合物及其在制备抗肿瘤药物中的应用
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* Cited by examiner, † Cited by third party
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US5721259A (en) * 1992-05-13 1998-02-24 Yale University Method of using 2-formylpyridine thiosemicarbazone compounds
CN102210698A (zh) * 2004-01-02 2011-10-12 维奥恩药品公司 包含3-氨基吡啶-2-甲醛缩氨基硫脲的癌症治疗
CN101260121A (zh) * 2007-03-07 2008-09-10 卡南吉医药科技（上海）有限公司 杂芳环缩氨基硫脲与过渡金属的络合物及其在制备抗肿瘤药物中的应用
MD3655G2 (ru) * 2007-09-03 2009-02-28 Государственный Университет Молд0 Ингибитор миелоидной лейкемии человека на основе бис(2-гидрокси-8-фенил-трицикло/7.3.1.0.2,7/-тридекан-13-он-тиосемикарбазонато)меди
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WO2010006438A1 (en) * 2008-07-17 2010-01-21 Critical Outcome Technologies Inc. Thiosemicarbazone inhibitor compounds and cancer treatment methods
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MD3995B1 (en) * 2009-05-11 2009-12-31 Universitatea De Stat Din Moldova Use of di(Á-Ophenoxy)-di{[2-(4-aminobenzenesulfamido)-5-ethyl-1,3,4-thiadiazole]-3,5-dibromosalicylidenethiosemicarbazonato(-1)-copper} as inhibitor of mammary cancer T-47D cell proliferation
MD3996B1 (en) * 2009-05-25 2009-12-31 Universitatea De Stat Din Moldova Perchlorates of 5-R-salicylidene-4-phenylthiosemicarbazonato(1-)-aquacopper(II) possessing properties of inhibitors of 17Beta-HSD enzyme activity (type 1)
MD4190B1 (en) * 2011-06-16 2012-12-31 Univ De Stat Din Moldova Inhibitor of human myeloid leukemia based on {bis¢2-(3,5-dibrom-2-hydroxyphenyl)-2-oxoethyl-piperidin-1-carbodithioato(1-)-O,O′]copper}
MD4215B1 (en) * 2012-07-09 2013-04-30 Univ De Stat Din Moldova Inhibitor of human myeloid leukemia based on N-(4-(5-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-2-(pyridin-2-ylmethylen)-hydrazinecarbothioamide

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