MA40713A1 - Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie du cancer du pancréas et d'autres cancers - Google Patents
Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie du cancer du pancréas et d'autres cancersInfo
- Publication number
- MA40713A1 MA40713A1 MA40713A MA40713A MA40713A1 MA 40713 A1 MA40713 A1 MA 40713A1 MA 40713 A MA40713 A MA 40713A MA 40713 A MA40713 A MA 40713A MA 40713 A1 MA40713 A1 MA 40713A1
- Authority
- MA
- Morocco
- Prior art keywords
- immunotherapy
- cancers
- pancreatic cancer
- present
- peptide combination
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 206010061902 Pancreatic neoplasm Diseases 0.000 title 1
- 238000009169 immunotherapy Methods 0.000 title 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 title 1
- 201000002528 pancreatic cancer Diseases 0.000 title 1
- 208000008443 pancreatic carcinoma Diseases 0.000 title 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 230000005975 antitumor immune response Effects 0.000 abstract 1
- 238000002619 cancer immunotherapy Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000001024 immunotherapeutic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001174—Proteoglycans, e.g. glypican, brevican or CSPG4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Reproductive Health (AREA)
Abstract
La présente invention concerne des peptides, des protéines, des acides nucléiques et des cellules à utiliser dans dans méthodes immunothérapeutiques. La présente invention concerne en particulier l'immunothérapie du cancer. La présente invention concerne en outre des épitopes peptidiques tumoraux de cellules t, seuls ou combinés à d'autres peptides tumoraux, qui peuvent par exemple servir d'ingrédients pharmaceutiques actifs de compositions vaccinales qui stimulent les réponses immunitaires antitumorales,
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201504502A GB201504502D0 (en) | 2015-03-17 | 2015-03-17 | Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers |
| PCT/EP2016/055817 WO2016146751A1 (fr) | 2015-03-17 | 2016-03-17 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie du cancer du pancréas et d'autres cancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA40713A1 true MA40713A1 (fr) | 2018-11-30 |
Family
ID=53016273
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA46648A MA46648B2 (fr) | 2015-03-17 | 2016-03-17 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie du cancer du pancréas et d'autres cancers |
| MA40713A MA40713A1 (fr) | 2015-03-17 | 2016-03-17 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie du cancer du pancréas et d'autres cancers |
| MA46647A MA46647A1 (fr) | 2015-03-17 | 2016-03-17 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie du cancer du pancréas et d'autres cancers |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA46648A MA46648B2 (fr) | 2015-03-17 | 2016-03-17 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie du cancer du pancréas et d'autres cancers |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA46647A MA46647A1 (fr) | 2015-03-17 | 2016-03-17 | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie du cancer du pancréas et d'autres cancers |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US10076560B2 (fr) |
| EP (1) | EP3270952A1 (fr) |
| JP (1) | JP6715856B2 (fr) |
| KR (1) | KR102718168B1 (fr) |
| CN (2) | CN107428810B (fr) |
| AR (2) | AR121587A2 (fr) |
| AU (4) | AU2016232140B2 (fr) |
| BR (1) | BR112017019217A2 (fr) |
| CA (1) | CA2979506A1 (fr) |
| CR (3) | CR20210233A (fr) |
| EA (1) | EA037783B1 (fr) |
| GB (1) | GB201504502D0 (fr) |
| MA (3) | MA46648B2 (fr) |
| MX (1) | MX2017011857A (fr) |
| PE (1) | PE20171515A1 (fr) |
| SG (2) | SG10202001404VA (fr) |
| TW (2) | TWI726872B (fr) |
| UA (1) | UA123392C2 (fr) |
| WO (1) | WO2016146751A1 (fr) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2943565B1 (fr) | 2013-01-14 | 2018-03-28 | Fred Hutchinson Cancer Research Center | Compositions et procédés pour l'administration de cellules immunitaires pour traiter des cellules tumorales non résécables ou non réséquées et une récidive de tumeur |
| HK1247842A1 (zh) | 2015-03-17 | 2018-10-05 | Immatics Biotechnologies Gmbh | 用於胰腺癌和其他癌症免疫治疗的新型肽和肽组合物 |
| EP3374399A1 (fr) | 2015-11-11 | 2018-09-19 | Opi Vi- IP Holdco LLC | Composition et méthodes pour anticorps anti-tnfr2 |
| CA3008641A1 (fr) | 2015-12-16 | 2017-06-22 | Gritstone Oncology, Inc. | Identification de neogenes, fabrication et utilisation |
| GB201604490D0 (en) | 2016-03-16 | 2016-04-27 | Immatics Biotechnologies Gmbh | Peptides combination of peptides for use in immunotherapy against cancers |
| JP7075125B2 (ja) | 2016-05-25 | 2022-05-25 | イマティクス バイオテクノロジーズ ゲーエムベーハー | 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ |
| GB201609193D0 (en) | 2016-05-25 | 2016-07-06 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides as targets for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers |
| NZ754222A (en) | 2016-12-08 | 2022-02-25 | Immatics Biotechnologies Gmbh | T cell receptors with improved pairing |
| DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
| JP7295360B2 (ja) * | 2016-12-21 | 2023-06-21 | モナーク・バイオサイエンシズ・インコーポレイテッド | 固形腫瘍細胞及びエスケープバリアントを治療するための足場 |
| CN111533797A (zh) * | 2017-04-10 | 2020-08-14 | 伊玛提克斯生物技术有限公司 | 用于癌症免疫治疗的肽及其肽组合物 |
| EP3630807B1 (fr) | 2017-05-25 | 2025-08-13 | Leidos, Inc. | Peptides d'inhibiteurs doubles de pd-1 et ctla-4 |
| DE102017115966A1 (de) | 2017-07-14 | 2019-01-17 | Immatics Biotechnologies Gmbh | Polypeptidmolekül mit verbesserter zweifacher Spezifität |
| BR112020000769A2 (pt) | 2017-07-14 | 2020-07-21 | Immatics Biotechnologies Gmbh | anticorpo de dupla especificidade, moléculas polipeptídicas, ácido nucleico, célula hospedeira, composição farmacêutica e método de tratamento de uma doença ou condição |
| EP3694532B1 (fr) | 2017-10-10 | 2025-02-26 | Gritstone bio, Inc. | Identification de néo-antigènes au moyen de points chauds |
| WO2019104203A1 (fr) | 2017-11-22 | 2019-05-31 | Gritstone Oncology, Inc. | Réduction de la présentation d'épitope de jonction pour des néo-antigènes |
| DE102017127984B4 (de) | 2017-11-27 | 2019-12-05 | Immatics US, Inc. | Verfahren für die Vermehrung und Aktivierung von γδ-T-Zellen |
| EP3749753B1 (fr) | 2018-02-09 | 2025-04-02 | Immatics US, Inc. | Procédés de fabrication de lymphocytes t |
| AU2018410849B2 (en) | 2018-02-27 | 2025-02-27 | Leidos, Inc. | PD-1 peptide inhibitors |
| WO2019175384A2 (fr) * | 2018-03-16 | 2019-09-19 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Peptides antigéniques dérivés de l'urocortine 3 et leurs utilisations pour le diagnostic et le traitement du diabète de type 1 |
| EP3765065A2 (fr) * | 2018-03-16 | 2021-01-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Peptides antigéniques dérivés de sécrétogranine v et leurs utilisations pour le diagnostic et le traitement du diabète de type 1 |
| DE102018108612A1 (de) | 2018-03-21 | 2019-09-26 | Immatics US, Inc. | Verfahren zur erhöhung der persistenz von adoptiv infundierten t-zellen |
| TW202039535A (zh) | 2018-12-18 | 2020-11-01 | 德商英麥提克生物技術股份有限公司 | B*08限制肽和肽組合物抗癌免疫治療和相關方法 |
| WO2020191172A1 (fr) | 2019-03-19 | 2020-09-24 | Immatics US, Inc. | Cultures de cellules t cd28, leurs compositions et leurs méthodes d'utilisation |
| EP3972696A1 (fr) | 2019-05-22 | 2022-03-30 | Leidos, Inc. | Peptides se liant à lag3 |
| CA3141505A1 (fr) | 2019-05-27 | 2020-12-03 | Immatics US, Inc. | Vecteurs viraux et leur utilisation dans une therapie cellulaire adoptive |
| ES2991645T3 (es) | 2019-06-06 | 2024-12-04 | Immatics Biotechnologies Gmbh | Clasificación con contraselección mediante péptidos de secuencia similar |
| US20210032370A1 (en) | 2019-08-02 | 2021-02-04 | Immatics Biotechnologies Gmbh | Recruiting agent further binding an mhc molecule |
| CN115427554A (zh) | 2020-02-24 | 2022-12-02 | 伊玛提克斯美国公司 | 扩增t细胞治疗癌症和相关恶性肿瘤的方法 |
| DE102020111571A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| DE102020106710A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| EP4143346B1 (fr) * | 2020-04-29 | 2026-01-07 | Eg Biomed Co., Ltd. | Méthode de détection précoce du cancer colorectal |
| JP7560850B2 (ja) * | 2020-07-01 | 2024-10-03 | 学校法人関西医科大学 | 尿路系上皮腫瘍関連病変を検出するためのバイオマーカー |
| EP4188947A2 (fr) | 2020-07-31 | 2023-06-07 | Leidos, Inc. | Peptides se liant à lag3 |
| WO2022040631A1 (fr) | 2020-08-21 | 2022-02-24 | Immatics US, Inc. | Procédés d'isolement de lymphocytes t sélectionnés cd8+ |
| US11987646B2 (en) | 2020-10-12 | 2024-05-21 | Leidos, Inc. | Immunomodulatory peptides |
| CN112557347B (zh) * | 2020-11-12 | 2023-10-24 | 渤海大学 | 一种黏液层中乳糜粒子迁移模型的制备及检测方法 |
| CN112462066B (zh) * | 2020-12-03 | 2023-05-19 | 中南大学湘雅医院 | Fam3c蛋白及其特异性抗体在制备检测鼻咽癌试剂盒中的应用、试剂盒及其应用 |
| KR20230135589A (ko) | 2020-12-31 | 2023-09-25 | 이매틱스 유에스 인코포레이티드 | Cd8 폴리펩타이드, 조성물 및 이의 사용 방법 |
| CN112760383B (zh) * | 2021-03-02 | 2023-07-21 | 上海欧易生物医学科技有限公司 | 应用于肺腺癌细胞亚群的一组qRT-PCR内参基因及其应用 |
| CN114163513B (zh) * | 2021-03-24 | 2025-02-25 | 深圳市新靶向生物科技有限公司 | 一种与肝癌驱动基因突变相关的抗原肽组合及其应用 |
| EP4334350A1 (fr) | 2021-05-05 | 2024-03-13 | Immatics Biotechnologies GmbH | Polypeptides de liaison à l'antigène bma031 |
| EP4392441A1 (fr) | 2021-08-24 | 2024-07-03 | Immatics US, Inc. | Sélection de cellules immunitaires à l'aide de complexes peptide-cmh générés par échange de ligands conditionnel |
| WO2023044488A1 (fr) | 2021-09-20 | 2023-03-23 | Immatics US, Inc. | Déplétion monocytaire des populations de lymphocytes t pour une thérapie par lymphocytes t |
| WO2023056240A2 (fr) | 2021-09-28 | 2023-04-06 | Frontaim Biomedicines, Inc. | Formats multiples de complexes moléculaires |
| US20230192886A1 (en) | 2021-11-08 | 2023-06-22 | Immatics Biotechnologies Gmbh | Adoptive cell therapy combination treatment and compositions thereof |
| KR102618065B1 (ko) * | 2021-12-10 | 2023-12-22 | 성균관대학교산학협력단 | 췌장암 진단용 조성물 및 이를 이용한 췌장암 진단 방법 |
| CN114214406A (zh) * | 2021-12-15 | 2022-03-22 | 天津医科大学总医院 | 一种用于评价肿瘤患者免疫治疗反应性和评估肿瘤预后的三联标志物及其应用 |
| IL316515A (en) | 2022-04-28 | 2024-12-01 | Immatics Us Inc | Membrane-bound IL15 CD8 proteins, cells, compositions and methods for their use |
| WO2023212691A1 (fr) | 2022-04-28 | 2023-11-02 | Immatics US, Inc. | Polypeptides récepteurs de tgfβ négatifs dominants, polypeptides cd8, cellules, compositions et leurs méthodes d'utilisation |
| EP4514821A1 (fr) | 2022-04-28 | 2025-03-05 | Immatics US, Inc. | Polypeptides d'il-12, polypeptides d'il-15, polypeptides d'il-18, polypeptides de cd8, compositions et leurs procédés d'utilisation |
| WO2023215825A1 (fr) | 2022-05-05 | 2023-11-09 | Immatics US, Inc. | Procédés d'amélioration de l'efficacité d'un lymphocyte t |
| US20250134931A1 (en) | 2023-11-01 | 2025-05-01 | Immatics US, Inc. | Membrane-bound il-15, cd8 polypeptides, cells, compositions, and methods of using thereof |
| CN119724622B (zh) * | 2024-11-25 | 2025-12-12 | 中国人民解放军总医院第五医学中心 | 一种评价ptt对胰腺癌治疗效果的方法、系统及设备 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5610031A (en) * | 1993-10-27 | 1997-03-11 | The General Hospital Corporation | B1k chain of laminin and methods of use |
| US6316213B1 (en) * | 1997-03-19 | 2001-11-13 | The Board Of Trustees Of The University Of Arkansas | Methods for the early diagnosis of ovarian, breast and lung cancer |
| WO1999064627A2 (fr) * | 1998-06-06 | 1999-12-16 | Genostic Pharma Limited | Sondes utilisees pour profilage genetique |
| AU3395900A (en) * | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| CA2392764A1 (fr) * | 1999-12-10 | 2001-06-14 | Epimmune Inc. | Induction de reponses immunes cellulaires a l'antigene carcinoembryonnaire a l'aide des compositions renfermant des peptides et des acides nucleiques |
| CA2393730A1 (fr) * | 1999-12-13 | 2001-06-14 | Epimmune Inc. | Compositions de vaccins et peptides d'antigene associes a une tumeur de hla-a2 de classe i |
| CN1469926A (zh) * | 2000-03-29 | 2004-01-21 | 科里克萨有限公司 | 治疗和诊断肺癌的组合物和方法 |
| WO2003010327A2 (fr) | 2001-02-21 | 2003-02-06 | Curagen Corporation | Nouvelles proteines et acides nucleiques les codant |
| US20030021796A1 (en) * | 2001-05-04 | 2003-01-30 | Leszek Ignatowicz | Method of enhancing T cell immunity by selection of antigen specific T cells |
| WO2003104428A2 (fr) * | 2002-01-21 | 2003-12-18 | Vaccinex, Inc. | Gene s'exprimant de façon differentielle dans le cancer du sein et de la vessie et polypeptides codes |
| JP2003321494A (ja) * | 2002-02-26 | 2003-11-11 | Daiichi Fine Chemical Co Ltd | プロmmp−7の活性化調節方法 |
| US20070224201A1 (en) * | 2002-10-02 | 2007-09-27 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| US20060252922A1 (en) * | 2002-12-04 | 2006-11-09 | Macina Roberto A | Compositions, splice variants and methods relating to colon specific genes and proteins |
| PL1731605T3 (pl) * | 2004-03-31 | 2010-08-31 | Int Inst Cancer Immunology Inc | Nowotworowe peptydy antygenowe pochodzące z WT1 |
| DK1760089T3 (da) * | 2005-09-05 | 2009-11-16 | Immatics Biotechnologies Gmbh | Tumor-associeret peptides bindende til human leukocyte antigen (HLA) class I eller II molecules og relateret anti-cancer vaccine |
| GB0611116D0 (en) * | 2006-06-06 | 2006-07-19 | Oxford Genome Sciences Uk Ltd | Proteins |
| WO2009015842A2 (fr) * | 2007-07-27 | 2009-02-05 | Immatics Biotechnologies Gmbh | Nouveaux épitopes immunogènes destinés à l'immunothérapie |
| EP2127664A1 (fr) * | 2008-02-15 | 2009-12-02 | Max-Delbrück-Centrum | Changement de l'état de charge de molécules MHC par des dipeptides |
| US20110117645A1 (en) * | 2008-03-31 | 2011-05-19 | Oriental Yeast Co., Ltd. | Method for proliferation of pluripotent stem cells |
| PT2119726E (pt) * | 2008-05-14 | 2015-03-30 | Immatics Biotechnologies Gmbh | Novos e poderosos peptídeos para mhc classe ii derivados de survinina e neurocano |
| WO2010047938A2 (fr) * | 2008-10-21 | 2010-04-29 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Détection de peptides d'activation mmp dans des échantillons biologiques |
| GB201004551D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| WO2011119484A1 (fr) * | 2010-03-23 | 2011-09-29 | Iogenetics, Llc | Procédés bioinformatiques pour déterminer la liaison de peptides |
| WO2013040142A2 (fr) * | 2011-09-16 | 2013-03-21 | Iogenetics, Llc | Procédés bio-informatiques de détermination de liaisons peptidiques |
| CA2840472A1 (fr) * | 2011-06-22 | 2012-12-27 | Oncocyte Corporation | Methodes et compositions pour traitement et diagnostique d'un cancer de la vessie |
| US20140206574A1 (en) * | 2011-08-31 | 2014-07-24 | Karen Chapman | Methods and Compositons for the Treatment and Diagnosis of Cancer |
| US20140065620A1 (en) * | 2011-12-29 | 2014-03-06 | Mayo Foundation For Medical Education And Research | Nucleic acids for detecting breast cancer |
| TWI777197B (zh) * | 2013-08-05 | 2022-09-11 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(六) |
| CN104163862B (zh) * | 2013-12-04 | 2017-02-08 | 魏敏杰 | 与人mhc‑i类分子结合的grp78多肽表位 |
| CN104306976A (zh) * | 2014-04-26 | 2015-01-28 | 深圳市康尔诺生物技术有限公司 | 一种高效的肿瘤个体化免疫治疗方法及其应用 |
-
2015
- 2015-03-17 GB GB201504502A patent/GB201504502D0/en not_active Ceased
-
2016
- 2016-03-17 SG SG10202001404VA patent/SG10202001404VA/en unknown
- 2016-03-17 CR CR20210233A patent/CR20210233A/es unknown
- 2016-03-17 MA MA46648A patent/MA46648B2/fr unknown
- 2016-03-17 TW TW105108310A patent/TWI726872B/zh active
- 2016-03-17 MA MA40713A patent/MA40713A1/fr unknown
- 2016-03-17 CN CN201680015234.0A patent/CN107428810B/zh active Active
- 2016-03-17 US US15/073,528 patent/US10076560B2/en active Active
- 2016-03-17 CN CN202110838669.8A patent/CN113563456A/zh active Pending
- 2016-03-17 AU AU2016232140A patent/AU2016232140B2/en not_active Ceased
- 2016-03-17 MA MA46647A patent/MA46647A1/fr unknown
- 2016-03-17 TW TW109140068A patent/TWI769586B/zh active
- 2016-03-17 BR BR112017019217-9A patent/BR112017019217A2/pt not_active Application Discontinuation
- 2016-03-17 WO PCT/EP2016/055817 patent/WO2016146751A1/fr not_active Ceased
- 2016-03-17 JP JP2017547530A patent/JP6715856B2/ja active Active
- 2016-03-17 CR CR20210234A patent/CR20210234A/es unknown
- 2016-03-17 CA CA2979506A patent/CA2979506A1/fr active Pending
- 2016-03-17 PE PE2017001485A patent/PE20171515A1/es unknown
- 2016-03-17 EP EP16710223.5A patent/EP3270952A1/fr active Pending
- 2016-03-17 CR CR20170419A patent/CR20170419A/es unknown
- 2016-03-17 UA UAA201707771A patent/UA123392C2/uk unknown
- 2016-03-17 KR KR1020177025935A patent/KR102718168B1/ko active Active
- 2016-03-17 MX MX2017011857A patent/MX2017011857A/es unknown
- 2016-03-17 EA EA201791853A patent/EA037783B1/ru unknown
- 2016-03-17 SG SG11201706155XA patent/SG11201706155XA/en unknown
-
2018
- 2018-01-12 US US15/869,471 patent/US10357551B2/en active Active
-
2020
- 2020-08-18 AU AU2020220073A patent/AU2020220073B2/en not_active Ceased
- 2020-08-18 AU AU2020220070A patent/AU2020220070B2/en not_active Ceased
- 2020-08-18 AU AU2020220072A patent/AU2020220072B2/en not_active Ceased
-
2021
- 2021-02-24 AR ARP210100472A patent/AR121587A2/es unknown
- 2021-02-24 AR ARP210100473A patent/AR121588A2/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA40713A1 (fr) | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie du cancer du pancréas et d'autres cancers | |
| MA40813A1 (fr) | Nouveaux peptides et combinaison de peptides destinés à être utilisés dans l'immunothérapie contre diverses tumeurs | |
| MA40794A1 (fr) | Nouveaux peptides et combinaisons de peptides et d'échafaudages destinés à être utilisés en immunothérapie contre le carcinome hépatocellulaire (chc) et d'autres cancers | |
| MA41879A1 (fr) | Nouveaux peptides et combinaison de peptides à utiliser en immunothérapie contre le cancer de la prostate et d'autres cancers | |
| MA41717A1 (fr) | Nouveaux peptides et combinaison de peptides destinés à être utilisés en immunothérapie contre le cancer ovarien épithélial et d'autres cancers | |
| MA39907B1 (fr) | Nouvelle immunothérapie contre plusieurs tumeurs, du sang, notamment la leucémie aiguë myéloïde (lam) | |
| MA43466A1 (fr) | Traitements du cancer de l'utérus | |
| MA43075A1 (fr) | Nouveaux peptides et combinaison de peptides pour une utilisation dans l'immunothérapie contre le lymphome non hodgkinien et d'autres cancers | |
| MA42021A1 (fr) | Nouveaux peptides et combinaison de peptides à utiliser en immunothérapie contre le cancer du poumon à petites cellules et d'autres cancers | |
| MA42020A1 (fr) | Peptides et combinaison de peptides à utiliser en immunothérapie contre le cancer du sein et d'autres cancers | |
| MA42073A1 (fr) | Nouveaux peptides et combinaison de peptides destinés à être utilisés dans l'immunothérapie contre divers cancers | |
| MA42072A1 (fr) | Nouveaux peptides et combinaison de peptides à utiliser en immunothérapie contre la cll et d'autres cancers | |
| MA41520B2 (fr) | Nouveaux peptides et combinaison de peptides à utiliser en immunothérapie contre le cancer de l'ovaire et d'autres cancers | |
| MA42294A (fr) | Nouveaux peptides et combinaison de peptides à utiliser en immunothérapie contre le cancer de l'ovaire et d'autres cancers | |
| MA41393A1 (fr) | Nouveaux peptides et combinaisons de peptides et échafaudages formés de ceux-ci destinés à être utilisés en immunothérapie contre le carcinome colorectal (crc) et d'autres cancers | |
| MA43618A1 (fr) | Nouveaux peptides, association de peptides en tant que cibles et destinés à être utilisés en immunothérapie contre le cancer de la vésicule biliaire et le cholangiocarcinome et autres cancers | |
| MA43460A1 (fr) | Nouveaux peptides, combinaisons de peptides et supports pour utilisation dans le traitementimmunothérapeutique de divers cancers | |
| MA43477A1 (fr) | Immunothérapie contre le mélanome et d'autres cancers | |
| MA41521A1 (fr) | Nouveaux épitopes de cellules et nouvelle combinaison d'épitopes de cellules destinés à être utilisés dans l'immunothérapie du myélome et d'autres cancers | |
| EA201690868A1 (ru) | Персонализированная иммунотерапия нескольких видов нейрональных опухолей и опухолей головного мозга | |
| MA43327A1 (fr) | Peptides et combinaison de peptides à utiliser en immunothérapie contre le cancer du poumon non à petites cellules et d'autres cancers | |
| EA201690016A1 (ru) | Новый метод иммунотерапии нескольких видов опухолей, таких как рак легкого, включая нмрл | |
| MA43482A1 (fr) | Nouveaux peptides et combinaison de peptides pour une utilisation dans l'immunothérapie contre la leucémie myéloïde aiguë (lma) et d'autres cancers | |
| MA42022A1 (fr) | Nouveaux peptides, combinaisons de peptides et supports pour utilisation dans le traitement immunothérapeutique de divers cancers | |
| EA201990696A1 (ru) | Персонализированная иммунотерапия нескольких видов нейрональных опухолей и опухолей головного мозга |