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MA38847A1 - Formulation médicamenteuse à libération retardée - Google Patents

Formulation médicamenteuse à libération retardée

Info

Publication number
MA38847A1
MA38847A1 MA38847A MA38847A MA38847A1 MA 38847 A1 MA38847 A1 MA 38847A1 MA 38847 A MA38847 A MA 38847A MA 38847 A MA38847 A MA 38847A MA 38847 A1 MA38847 A1 MA 38847A1
Authority
MA
Morocco
Prior art keywords
release
delayed
soluble
delayed release
inner layer
Prior art date
Application number
MA38847A
Other languages
English (en)
Other versions
MA38847B2 (fr
Inventor
González Roberto Carlos Bravo
Thomas Buser
Felipe José Oliveira Varum
Abdul Waseh Basit
Ana Cristina Freire
Original Assignee
Tillotts Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tillotts Pharma Ag filed Critical Tillotts Pharma Ag
Publication of MA38847A1 publication Critical patent/MA38847A1/fr
Publication of MA38847B2 publication Critical patent/MA38847B2/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005—Coating of tablets or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/606—Salicylic acid; Derivatives thereof having amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Dans une formulation à libération retardée comprenant un noyau contenant un médicament et un enrobage à libération retardée pour assurer la libération intestinale, la libération du médicament dans le côlon est accélérée par l'inclusion d'une couche isolante entre le noyau et l'enrobage à libération retardée. L'enrobage à libération retardée comprend une couche interne et une couche externe. La couche externe comprend une substance polymère soluble en fonction du ph dont le seuil de ph avoisine ph 5 ou plus. La couche interne comprend une substance polymère soluble qui est soluble dans le liquide intestinal ou le liquide gastro-intestinal, ladite substance polymère soluble étant choisie dans le groupe constitué d'un polymère d'acide polycarboxylique qui est au moins partiellement neutralisé, et d'un polymère non ionique, à condition que, lorsque ladite substance polymère soluble est un polymère non ionique, ladite couche interne comprenne au moins un additif choisi parmi un agent tampon et une base.
MA38847A 2013-10-29 2013-10-29 Formulation médicamenteuse à libération retardée MA38847B2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2013/072648 WO2015062640A1 (fr) 2013-10-29 2013-10-29 Formulation médicamenteuse à libération retardée

Publications (2)

Publication Number Publication Date
MA38847A1 true MA38847A1 (fr) 2017-08-31
MA38847B2 MA38847B2 (fr) 2021-02-26

Family

ID=49515360

Family Applications (1)

Application Number Title Priority Date Filing Date
MA38847A MA38847B2 (fr) 2013-10-29 2013-10-29 Formulation médicamenteuse à libération retardée

Country Status (25)

Country Link
US (1) US10799515B2 (fr)
EP (2) EP3062776A1 (fr)
JP (1) JP6273356B2 (fr)
KR (2) KR102174942B1 (fr)
CN (2) CN110279669B (fr)
AU (2) AU2013404367B2 (fr)
BR (2) BR122020013726B1 (fr)
CA (1) CA2923063C (fr)
CR (1) CR20160192A (fr)
CU (1) CU20160055A7 (fr)
EA (1) EA032504B1 (fr)
HK (1) HK1222547A1 (fr)
IL (2) IL244260B (fr)
MA (1) MA38847B2 (fr)
MX (2) MX382146B (fr)
MY (1) MY189394A (fr)
NZ (2) NZ747731A (fr)
PH (2) PH12020551522A1 (fr)
SA (2) SA116370660B1 (fr)
SG (1) SG11201600501UA (fr)
TN (1) TN2016000119A1 (fr)
TW (3) TWI736031B (fr)
UA (1) UA117260C2 (fr)
WO (1) WO2015062640A1 (fr)
ZA (1) ZA201600630B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE036187T2 (hu) 2012-04-30 2018-06-28 Tillotts Pharma Ag Késleltetett leadású gyógyszerkészítmény
JP6830671B6 (ja) 2015-09-23 2021-03-10 エックスダブリューファルマ リミテッド γ−ヒドロキシ酪酸（ＧＨＢ）のプロドラッグ、その組成物および使用
EP3162362A1 (fr) * 2015-10-30 2017-05-03 Dr. Falk Pharma Gmbh Comprimé optimisé a une haute dose contenant de la mesalazine
EP3257501A1 (fr) 2016-06-14 2017-12-20 Tillotts Pharma AG Forme galénique unitaire multiple comprenant un noyau avec différentes unités de coeur recouvertes par un matériau muco-adhésif et un revêtement noyau gastro-résistant
MX2020007358A (es) * 2017-12-21 2020-09-07 Pepsico Inc Capsula de bebida efimera de multiples ingredientes para preparar una bebida.
EP3662898A1 (fr) * 2018-12-07 2020-06-10 Tillotts Pharma AG Formulation solide comprenant de la mésalamine
ES2994844T3 (en) * 2018-12-07 2025-02-03 Tillotts Pharma Ag Colonic drug delivery formulation
EP3662900A1 (fr) * 2018-12-07 2020-06-10 Tillotts Pharma AG Formulation d'administration de médicament colonique
EP3662895A1 (fr) 2018-12-07 2020-06-10 Tillotts Pharma AG Procédé de fabrication de noyaux de comprimés réduisant le 5-asa sans sucre
ES3002632T3 (en) 2018-12-07 2025-03-07 Tillotts Pharma Ag Delayed release drug formulation comprising an outerlayer with an enzymatically degradable polymer, its composition and its method of manufacturing
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CN114786652A (zh) * 2019-12-11 2022-07-22 赢创运营有限公司 用于治疗或预防疾病的剂型

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Also Published As

Publication number Publication date
WO2015062640A1 (fr) 2015-05-07
CA2923063C (fr) 2021-09-07
CA2923063A1 (fr) 2015-05-07
SA114360006B1 (ar) 2016-11-09
KR20200075041A (ko) 2020-06-25
HK1222547A1 (zh) 2017-07-07
EP3062776A1 (fr) 2016-09-07
CN110279669A (zh) 2019-09-27
AU2013404367A1 (en) 2016-02-18
MX2019002162A (es) 2019-06-17
TW202011945A (zh) 2020-04-01
NZ747731A (en) 2020-02-28
MX388063B (es) 2025-03-19
MY189394A (en) 2022-02-09
AU2013404367B2 (en) 2020-02-27
EA032504B1 (ru) 2019-06-28
AU2020201365B2 (en) 2021-09-16
TN2016000119A1 (en) 2017-10-06
PH12016500307A1 (en) 2016-05-16
KR102174942B1 (ko) 2020-11-06
TW201542243A (zh) 2015-11-16
US10799515B2 (en) 2020-10-13
IL265381A (en) 2019-05-30
US20160250232A1 (en) 2016-09-01
BR112016004863A8 (pt) 2020-02-11
KR102237356B1 (ko) 2021-04-08
JP2016535030A (ja) 2016-11-10
KR20160077040A (ko) 2016-07-01
MX382146B (es) 2025-03-13
JP6273356B2 (ja) 2018-01-31
PH12020551522A1 (en) 2022-11-14
NZ717159A (en) 2019-06-28
IL244260B (en) 2021-08-31
ZA201600630B (en) 2017-05-31
UA117260C2 (uk) 2018-07-10
CN105555260A (zh) 2016-05-04
TWI725458B (zh) 2021-04-21
TW201944984A (zh) 2019-12-01
MA38847B2 (fr) 2021-02-26
IL244260A0 (en) 2016-04-21
BR122020013726B1 (pt) 2022-11-01
CU20160055A7 (es) 2016-10-28
EA201690596A1 (ru) 2016-08-31
TWI680774B (zh) 2020-01-01
CR20160192A (es) 2016-07-13
CN110279669B (zh) 2022-02-15
CN105555260B (zh) 2021-04-23
SA116370660B1 (ar) 2019-02-24
SG11201600501UA (en) 2016-02-26
TWI736031B (zh) 2021-08-11
MX2016001840A (es) 2016-08-11
IL265381B (en) 2022-05-01
PH12016500307B1 (en) 2022-02-11
AU2020201365A1 (en) 2020-03-12
EP3542791A1 (fr) 2019-09-25
BR112016004863B1 (pt) 2022-09-20

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