MA38774A1 - Substituted pyrazolo-pyridinamines inhibitors of mknk1 kinase for use in hyperproliferative and / or angiogenesis disorders. - Google Patents
Substituted pyrazolo-pyridinamines inhibitors of mknk1 kinase for use in hyperproliferative and / or angiogenesis disorders.Info
- Publication number
- MA38774A1 MA38774A1 MA38774A MA38774A MA38774A1 MA 38774 A1 MA38774 A1 MA 38774A1 MA 38774 A MA38774 A MA 38774A MA 38774 A MA38774 A MA 38774A MA 38774 A1 MA38774 A1 MA 38774A1
- Authority
- MA
- Morocco
- Prior art keywords
- compounds
- hyperproliferative
- pyridinamines
- inhibitors
- substituted pyrazolo
- Prior art date
Links
- 230000033115 angiogenesis Effects 0.000 title abstract 2
- 230000003463 hyperproliferative effect Effects 0.000 title abstract 2
- MJEPPEQNLZSPAP-UHFFFAOYSA-N 1h-pyrazolo[4,3-b]pyridin-3-amine Chemical class C1=CN=C2C(N)=NNC2=C1 MJEPPEQNLZSPAP-UHFFFAOYSA-N 0.000 title 1
- 101150115334 Mknk1 gene Proteins 0.000 title 1
- 108091000080 Phosphotransferase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 102000020233 phosphotransferase Human genes 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000005229 pyrazolopyridines Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La présente invention porte sur des composés pyrazolopyridine substitués représentés par la formule générale (i), tels que décrits et définis dans la description, sur des procédés de préparation desdits composés, sur des composés intermédiaires utiles pour la préparation desdits composés, sur des associations et des compositions pharmaceutiques comprenant lesdits composés et sur l'utilisation desdits composés pour la fabrication d'une composition pharmaceutique pour le traitement ou la prophylaxie d'une maladie, en particulier d'un trouble hyperprolifératif et/ou relatif à l'angiogenèse, en tant qu'agent unique ou en association avec d'autres principes actifs.The present invention relates to substituted pyrazolopyridine compounds represented by the general formula (i), as described and defined in the description, to processes for the preparation of said compounds, to intermediate compounds useful for the preparation of said compounds, to combinations and pharmaceutical compositions comprising said compounds and the use of said compounds for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular a hyperproliferative and / or angiogenesis disorder, as a as a single agent or in combination with other active ingredients.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13175526 | 2013-07-08 | ||
| PCT/EP2014/064347 WO2015004024A1 (en) | 2013-07-08 | 2014-07-04 | Substituted pyrazolo-pyridinamines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA38774A1 true MA38774A1 (en) | 2018-05-31 |
Family
ID=48745840
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA38774A MA38774A1 (en) | 2013-07-08 | 2014-07-04 | Substituted pyrazolo-pyridinamines inhibitors of mknk1 kinase for use in hyperproliferative and / or angiogenesis disorders. |
Country Status (2)
| Country | Link |
|---|---|
| AR (1) | AR096826A1 (en) |
| MA (1) | MA38774A1 (en) |
-
2014
- 2014-07-04 MA MA38774A patent/MA38774A1/en unknown
- 2014-07-07 AR ARP140102510A patent/AR096826A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR096826A1 (en) | 2016-02-03 |
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