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MA33434B1 - Traitement de bouffées de chaleur, de symptômes vasomoteurs et de sueurs nocturnes par des précurseurs de stéroïdes sexuels en combinaison avec des modulateurs sélectifs du récepteur de l'oestrogène - Google Patents

Traitement de bouffées de chaleur, de symptômes vasomoteurs et de sueurs nocturnes par des précurseurs de stéroïdes sexuels en combinaison avec des modulateurs sélectifs du récepteur de l'oestrogène

Info

Publication number
MA33434B1
MA33434B1 MA34540A MA34540A MA33434B1 MA 33434 B1 MA33434 B1 MA 33434B1 MA 34540 A MA34540 A MA 34540A MA 34540 A MA34540 A MA 34540A MA 33434 B1 MA33434 B1 MA 33434B1
Authority
MA
Morocco
Prior art keywords
symptoms
precursors
treatment
loss
administration
Prior art date
Application number
MA34540A
Other languages
Arabic (ar)
English (en)
Inventor
Fernand Labrie
Original Assignee
Endorech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43306950&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA33434(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Endorech Inc filed Critical Endorech Inc
Publication of MA33434B1 publication Critical patent/MA33434B1/fr

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    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
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  • Public Health (AREA)
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  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'INVENTION PORTE SUR DE NOUVEAUX PROCÉDÉS POUR LA RÉDUCTION OU L'ÉLIMINATION DE L'INCIDENCE DE BOUFFÉES DE CHALEUR, DE SYMPTÔMES VASOMOTEURS ET DE SUEURS NOCTURNES TOUT EN DIMINUANT LE RISQUE D'ACQUÉRIR UN CANCER DU SEIN, DE L'UTÉRUS OU DE L'ENDOMÈTRE ET EN PRÉSENTANT DE PLUS UN EFFET BÉNÉFIQUE PAR L'INHIBITION DU DÉVELOPPEMENT DE L'OSTÉOPOROSE, DE L'HYPERCHOLESTÉROLÉMIE, DE L'HYPERLIPIDÉMIE, DE L'ATHÉROSCLÉROSE, DE L'HYPERTENSION, DE LA RÉSISTANCE À L'INSULINE, DU DIABÈTE DE TYPE 2, DE LA PERTE DE MASSE MUSCULAIRE, DE L'ADIPOSITÉ, DE LA MALADIE D'ALZHEIMER, DE LA PERTE DE COGNITION, DE LA PERTE DE MÉMOIRE OU DE LA SÉCHERESSE VAGINALE CHEZ DES ANIMAUX À SANG CHAUD SUSCEPTIBLES, COMPRENANT LES ÊTRES HUMAINS, QUI ENTRAÎNE L'ADMINISTRATION D'UNE CERTAINE QUANTITÉ D'UN PRÉCURSEUR DE STÉROÏDE SEXUEL, EN PARTICULIER LA DÉHYDROÉPIANDROSTÉRONE (DHEA) ET UN ANTI-'STROGÈNE OU UN MODULATEUR SÉLECTIF DU RÉCEPTEUR DE L''STROGÈNE SÉLECTIF, EN PARTICULIER DES COMPOSÉS BENZOPYRANES. L'INVENTION PORTE ÉGALEMENT SUR DES COMPOSITIONS PHARMACEUTIQUES DESTINÉES À L'ADMINISTRATION D'UN OU DE PLUSIEURS AGENTS ACTIFS ET SUR UN OU PLUSIEURS NÉCESSAIRES UTILES À L'INVENTION.
MA34540A 2009-06-16 2010-06-16 Traitement de bouffées de chaleur, de symptômes vasomoteurs et de sueurs nocturnes par des précurseurs de stéroïdes sexuels en combinaison avec des modulateurs sélectifs du récepteur de l'oestrogène MA33434B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18754909P 2009-06-16 2009-06-16
US12/791,174 US20100317635A1 (en) 2009-06-16 2010-06-01 Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators
PCT/CA2010/000898 WO2010145010A1 (fr) 2009-06-16 2010-06-16 Traitement de bouffées de chaleur, de symptômes vasomoteurs et de sueurs nocturnes par des précurseurs de stéroïdes sexuels en combinaison avec des modulateurs sélectifs du récepteur de l'œstrogène

Publications (1)

Publication Number Publication Date
MA33434B1 true MA33434B1 (fr) 2012-07-03

Family

ID=43306950

Family Applications (1)

Application Number Title Priority Date Filing Date
MA34540A MA33434B1 (fr) 2009-06-16 2010-06-16 Traitement de bouffées de chaleur, de symptômes vasomoteurs et de sueurs nocturnes par des précurseurs de stéroïdes sexuels en combinaison avec des modulateurs sélectifs du récepteur de l'oestrogène

Country Status (20)

Country Link
US (4) US20100317635A1 (fr)
EP (3) EP3178480A1 (fr)
JP (4) JP2012530074A (fr)
KR (10) KR20210048609A (fr)
CN (3) CN104352504A (fr)
AR (1) AR077119A1 (fr)
AU (1) AU2010262722A1 (fr)
BR (1) BRPI1011561A2 (fr)
CA (2) CA2765446A1 (fr)
CL (1) CL2011003172A1 (fr)
EA (1) EA201200016A1 (fr)
HK (1) HK1204550A1 (fr)
IL (2) IL216963A (fr)
MA (1) MA33434B1 (fr)
MX (1) MX338290B (fr)
NZ (1) NZ597583A (fr)
SG (3) SG177497A1 (fr)
TW (1) TWI612044B (fr)
WO (1) WO2010145010A1 (fr)
ZA (1) ZA201109198B (fr)

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US8268806B2 (en) 2007-08-10 2012-09-18 Endorecherche, Inc. Pharmaceutical compositions
EP2580210B1 (fr) 2010-06-10 2017-03-01 Seragon Pharmaceuticals, Inc. Modulateur du récepteur oestrogénique et utilisation de ces derniers
CN103796643B (zh) * 2011-07-19 2016-06-22 潘塔希生物科学股份有限公司 含有脱氢表雄酮(dhea)的片剂
EP2791132A4 (fr) 2011-12-14 2015-08-05 Seragon Pharmaceuticals Inc Modulateurs des récepteurs des strogènes et ses utilisations
AP2014007657A0 (en) 2011-12-16 2014-05-31 Olema Pharmaceuticals Inc Novel benzopyran compounds, compositions and uses thereof
WO2013134311A1 (fr) * 2012-03-07 2013-09-12 Ligand Pharmaceuticals, Inc. Voies des hormones stéroïdiennes et du cholestérol sous la forme d'un système homéostatique unifié
WO2014008159A1 (fr) * 2012-07-03 2014-01-09 The University Of North Carolina At Chapel Hill Agents de dégradation sélectifs de récepteur des œstrogènes pour le traitement de tumeurs résistantes au tamoxifène
WO2014203129A1 (fr) 2013-06-19 2014-12-24 Olema Pharmaceuticals, Inc. Combinaisons de composés benzopyrane, leurs compositions et utilisations
WO2014203132A1 (fr) 2013-06-19 2014-12-24 Olema Pharmaceuticals, Inc. Composés de benzopyran substitués, leurs compositions et utilisations
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